ES2098247T3 - Preparacion medicamentosa polimerizada hidro-soluble de elevado peso molecular. - Google Patents

Preparacion medicamentosa polimerizada hidro-soluble de elevado peso molecular.

Info

Publication number
ES2098247T3
ES2098247T3 ES90302962T ES90302962T ES2098247T3 ES 2098247 T3 ES2098247 T3 ES 2098247T3 ES 90302962 T ES90302962 T ES 90302962T ES 90302962 T ES90302962 T ES 90302962T ES 2098247 T3 ES2098247 T3 ES 2098247T3
Authority
ES
Spain
Prior art keywords
hydro
molecular weight
high molecular
medicinal preparation
soluble polymerized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90302962T
Other languages
English (en)
Inventor
Yasuhisa Sakurai
Teruo Okano
Kazunori Kataoka
Noriko Yamada
Shohei Inoue
Masayuki Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Science and Technology Agency
Original Assignee
Research Development Corp of Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Corp of Japan filed Critical Research Development Corp of Japan
Application granted granted Critical
Publication of ES2098247T3 publication Critical patent/ES2098247T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)

Abstract

SE PRESENTA UN COPOLIMERO DE BLOQUE SOLUBLE EN AGUA QUE COMPRENDE UN SEGMENTO HIDROFILICO Y UN SEGMENTO HIDROFOBICO QUE CONTIENE UNA PARTE DE CADENA LATERAL FARMACOLOGICAMENTE ACTIVA. EL PRIMER SEGMENTO HIDROFILICO DEL PRESENTE INVENTO ES GLICOL DE POLIETILENO ADECUADO, POLISACARIDOS O POLIACRILAMIDO. EL SEGMENTO HIDROFOBICO INCLUYE ACIDO POLIASPARTICO, ACIDO POLIGLUCTAMICO, POLILISINA, O DERIVADOS DE LOS MISMOS.
ES90302962T 1989-05-11 1990-03-20 Preparacion medicamentosa polimerizada hidro-soluble de elevado peso molecular. Expired - Lifetime ES2098247T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1116082A JP2517760B2 (ja) 1989-05-11 1989-05-11 水溶性高分子化医薬製剤

Publications (1)

Publication Number Publication Date
ES2098247T3 true ES2098247T3 (es) 1997-05-01

Family

ID=14678267

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90302962T Expired - Lifetime ES2098247T3 (es) 1989-05-11 1990-03-20 Preparacion medicamentosa polimerizada hidro-soluble de elevado peso molecular.

Country Status (8)

Country Link
US (2) US5412072A (es)
EP (1) EP0397307B1 (es)
JP (1) JP2517760B2 (es)
KR (1) KR920006912B1 (es)
AU (1) AU640927B2 (es)
CA (1) CA2016505C (es)
DE (1) DE69029006T2 (es)
ES (1) ES2098247T3 (es)

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US5693751A (en) 1997-12-02
CA2016505C (en) 2001-02-13
JPH02300133A (ja) 1990-12-12
AU5469990A (en) 1990-11-15
JP2517760B2 (ja) 1996-07-24
KR900017574A (ko) 1990-12-19
AU640927B2 (en) 1993-09-09
KR920006912B1 (ko) 1992-08-22
EP0397307A2 (en) 1990-11-14
CA2016505A1 (en) 1990-11-11
DE69029006D1 (de) 1996-12-05
US5412072A (en) 1995-05-02
EP0397307A3 (en) 1991-04-10
EP0397307B1 (en) 1996-10-30
DE69029006T2 (de) 1997-03-06

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