ES2101332T3 - Procedimiento para la obtencion de policarboxilatos a base de polisacaridos. - Google Patents

Procedimiento para la obtencion de policarboxilatos a base de polisacaridos.

Info

Publication number
ES2101332T3
ES2101332T3 ES93917384T ES93917384T ES2101332T3 ES 2101332 T3 ES2101332 T3 ES 2101332T3 ES 93917384 T ES93917384 T ES 93917384T ES 93917384 T ES93917384 T ES 93917384T ES 2101332 T3 ES2101332 T3 ES 2101332T3
Authority
ES
Spain
Prior art keywords
polysaccharides
groups
procedure
obtaining
polycarboxylates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93917384T
Other languages
English (en)
Inventor
Konrad Engelskirchen
Herbert Fischer
Hans-Wilhelm Verholt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Application granted granted Critical
Publication of ES2101332T3 publication Critical patent/ES2101332T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/18—Oxidised starch
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/02—Oxycellulose; Hydrocellulose; Cellulosehydrate, e.g. microcrystalline cellulose
    • C08B15/04—Carboxycellulose, e.g. prepared by oxidation with nitrogen dioxide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/22—Carbohydrates or derivatives thereof
    • C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
    • C11D3/223—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin oxidised

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA LA ELABORACION DE ACIDOS POLICARBOXILICOS O SUS SALES A PARTIR DE POLISACARIDOS MEDIANTE OXIDACION CON DIOXIDO DE NITROGENO/TETROXIDO DE DINITROGENO, CON LA CONVERSION DE AL MENOS UNA PARTE DE LOS GRUPOS DE ALCOHOL PRIMARIO DE LOS POLISACARIDOS EN GRUPOS CARBOXIL Y DONDE DE FORMA APROPIADA SE PRODUCE AL MENOS UNA NEUTRALIZACION PARCIAL DE LOS GRUPOS DE ACIDO CARBOXILICO, SIENDO ACORTADO EL TIEMPO DE REACCION REQUERIDO Y REDUCIDO LA CANTIDAD NECESARIA DE DIOXIDO DE NITROGENO. SE CONSIGUE ESENCIALMENTE QUE LA REACCION DE OXIDACION ESTE ACOMPAÑADA POR TEMPERATURAS POR ENCIMA DEL AMBIENTE EN PRESENCIA DE OXIGENO. LOS POLICARBOXILATOS RESULTANTES SON, POR EJEMPLO, UTILIZADOS COMO FORMADORES O CONFORMADORES DE AGENTES DE LAVADO O DE LIMPIEZA.
ES93917384T 1992-02-11 1993-02-03 Procedimiento para la obtencion de policarboxilatos a base de polisacaridos. Expired - Lifetime ES2101332T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4203923A DE4203923A1 (de) 1992-02-11 1992-02-11 Verfahren zur herstellung von polycarboxylaten auf polysaccharid-basis

Publications (1)

Publication Number Publication Date
ES2101332T3 true ES2101332T3 (es) 1997-07-01

Family

ID=6451390

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93917384T Expired - Lifetime ES2101332T3 (es) 1992-02-11 1993-02-03 Procedimiento para la obtencion de policarboxilatos a base de polisacaridos.

Country Status (6)

Country Link
US (1) US5541316A (es)
EP (1) EP0625992B1 (es)
JP (1) JPH07503495A (es)
DE (2) DE4203923A1 (es)
ES (1) ES2101332T3 (es)
WO (1) WO1993016110A1 (es)

Families Citing this family (329)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317519A1 (de) * 1993-05-26 1994-12-01 Henkel Kgaa Herstellung von Polycarboxylaten auf Polysaccharid-Basis
DE4330339A1 (de) * 1993-09-08 1995-03-09 Henkel Kgaa Scale-Inhibitor auf Kohlehydratbasis
DE4403323A1 (de) * 1993-09-23 1995-08-10 Henkel Kgaa Extrudierte Wasch- oder Reinigungsmittel mit verbesserten Löseeigenschaften
DE4400024A1 (de) * 1994-01-03 1995-07-06 Henkel Kgaa Silikatische Builder und ihre Verwendung in Wasch- und Reinigungsmitteln sowie Mehrstoffgemische für den Einsatz auf diesem Sachgebiet
DE4402851A1 (de) * 1994-01-31 1995-08-03 Henkel Kgaa Wirbelschicht-Oxidationsverfahren zur Herstellung von Polycarboxylaten auf Polysaccharid-Basis
DE4404279A1 (de) * 1994-02-10 1995-08-17 Henkel Kgaa Tablette mit Buildersubstanzen
DE4405511A1 (de) * 1994-02-22 1995-08-24 Henkel Kgaa Waschmittel mit amorphen silikatischen Buildersubstanzen
US5691295A (en) * 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
DE4406592A1 (de) * 1994-03-01 1995-09-07 Henkel Kgaa Verbesserte Mehrstoffgemische auf Basis wasserlöslicher Alkalisilikatverbindungen und ihre Verwendung, insbesondere zum Einsatz als Builder in Wasch- und Reinigungsmitteln
DE4415362A1 (de) * 1994-05-02 1995-11-09 Henkel Kgaa Verfahren zur Herstellung silikatischer Buildergranulate mit erhöhtem Schüttgewicht
DE4422433A1 (de) * 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
DE4426443A1 (de) * 1994-07-26 1996-02-01 Henkel Kgaa Verbessertes Verfahren zur Herstellung von Polycarboxylaten durch Oxidation von Polysacchariden
DE4429550A1 (de) * 1994-08-19 1996-02-22 Henkel Kgaa Verfahren zur Herstellung von Wasch- oder Reinigungsmitteltabletten
DE4439681A1 (de) * 1994-11-07 1996-05-09 Henkel Kgaa Verwendung von Polyglucosan-Oxidationsprodukten als Builder in Reinigungsmitteln für harte Oberflächen
DE4439679A1 (de) * 1994-11-07 1996-05-09 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Herstellung von Wasch- und Reinigungsmitteltabletten durch Mikrowellen- und Heißluftbehandlung
DE19500644B4 (de) * 1995-01-12 2010-09-09 Henkel Ag & Co. Kgaa Sprühgetrocknetes Waschmittel oder Komponente hierfür
DE19501269A1 (de) 1995-01-18 1996-07-25 Henkel Kgaa Amorphes Alkalisilikat-Compound
DE19507717A1 (de) * 1995-03-07 1996-09-12 Henkel Kgaa Verfahren zur Herstellung von neutralisierten Polycarboxylaten auf Polysaccharid-Basis
DE19510313A1 (de) * 1995-03-22 1996-09-26 Henkel Kgaa Verbessertes Oxidationsverfahren zur Herstellung von Polycarboxylaten aus Polysacchariden
DE19515072A1 (de) * 1995-04-28 1996-10-31 Cognis Bio Umwelt Cellulasehaltiges Waschmittel
US6313081B1 (en) 1995-04-28 2001-11-06 Henkel Kommanditgesellschaft Auf Aktien (Kgaa) Detergents comprising cellulases
GB9509287D0 (en) * 1995-05-06 1995-06-28 Solvay Interox Ltd Detergent builder/activators
DE19525378A1 (de) * 1995-07-12 1997-01-16 Henkel Kgaa Amorphes Alkalisilicat-Compound
DE19545729A1 (de) 1995-12-08 1997-06-12 Henkel Kgaa Bleich- und Waschmittel mit enzymatischem Bleichsystem
DE19600018A1 (de) 1996-01-03 1997-07-10 Henkel Kgaa Waschmittel mit bestimmten oxidierten Oligosacchariden
DE19605688A1 (de) * 1996-02-16 1997-08-21 Henkel Kgaa Übergangsmetallkomplexe als Aktivatoren für Persauerstoffverbindungen
EP0891415A1 (de) 1996-04-01 1999-01-20 Henkel Kommanditgesellschaft auf Aktien Reinigungsmittel mit oligoamminaktivatorkomplexen für persauerstoffverbindungen
DE19620411A1 (de) 1996-04-01 1997-10-02 Henkel Kgaa Übergangsmetallamminkomplexe als Aktivatoren für Persauerstoffverbindungen
DE19616693A1 (de) * 1996-04-26 1997-11-06 Henkel Kgaa Enolester als Bleichaktivatoren für Wasch- und Reinigungsmittel
DE19709411A1 (de) 1997-03-07 1998-09-10 Henkel Kgaa Waschmittelformkörper
DE19713852A1 (de) 1997-04-04 1998-10-08 Henkel Kgaa Aktivatoren für Persauerstoffverbindungen in Wasch- und Reinigungsmitteln
DE19725508A1 (de) 1997-06-17 1998-12-24 Clariant Gmbh Wasch- und Reinigungsmittel
DE19732749A1 (de) 1997-07-30 1999-02-04 Henkel Kgaa Glucanasehaltiges Waschmittel
DE19732751A1 (de) 1997-07-30 1999-02-04 Henkel Kgaa Neue Beta-Glucanase aus Bacillus
DE19732750A1 (de) 1997-07-30 1999-02-04 Henkel Kgaa Glucanasehaltiges Reinigungsmittel für harte Oberflächen
US6200498B1 (en) 1997-08-29 2001-03-13 Henkel Kommanditgesellschaft Auf Aktien Process for producing paraffin-containing foam regulators
US6440940B1 (en) 1997-12-18 2002-08-27 Peter J. Doyle Bioresorbable alginate derivatives
DE19801186A1 (de) 1998-01-15 1999-07-22 Henkel Kgaa Verfahren zur Herstellung gefärbter Wasch- und Reinigungsmittel
DE19824705A1 (de) 1998-06-03 1999-12-09 Henkel Kgaa Amylase und Protease enthaltende Wasch- und Reinigungsmittel
DE19850100A1 (de) 1998-10-29 2000-05-04 Henkel Kgaa Polymer-Granulate durch Wirbelschichtgranulation
DE19914811A1 (de) 1999-03-31 2000-10-05 Henkel Kgaa Enzym- und bleichaktivatorhaltige Wasch- und Reinigungsmittel
WO2001004258A1 (de) 1999-07-09 2001-01-18 Henkel Kommanditgesellschaft Auf Aktien Wasch- oder reinigungsmittel-portion
DE19936613B4 (de) 1999-08-04 2010-09-02 Henkel Ag & Co. Kgaa Verfahren zur Herstellung eines Waschmittels mit löslichem Buildersystem
DE19940547A1 (de) 1999-08-26 2001-03-01 Henkel Kgaa Wasch- oder Reinigungsmittelformkörper mit Partialcoating
DE19944218A1 (de) 1999-09-15 2001-03-29 Cognis Deutschland Gmbh Waschmitteltabletten
US6610752B1 (en) 1999-10-09 2003-08-26 Cognis Deutschland Gmbh Defoamer granules and processes for producing the same
US6686327B1 (en) 1999-10-09 2004-02-03 Cognis Deutschland Gmbh & Co. Kg Shaped bodies with improved solubility in water
DE19953792A1 (de) 1999-11-09 2001-05-17 Cognis Deutschland Gmbh Waschmitteltabletten
DE19956803A1 (de) 1999-11-25 2001-06-13 Cognis Deutschland Gmbh Tensidgranulate mit verbesserter Auflösegeschwindigkeit
DE19956802A1 (de) 1999-11-25 2001-06-13 Cognis Deutschland Gmbh Waschmitteltabletten
DE19962885A1 (de) * 1999-12-24 2001-07-05 Cognis Deutschland Gmbh Wasch- und Reinigungsmittelformkörper mit verbesserten Zerfallseigenschaften
DE19962886A1 (de) 1999-12-24 2001-07-05 Cognis Deutschland Gmbh Tensidgranulate mit verbesserter Auflösegeschwindigkeit
DE19962883A1 (de) * 1999-12-24 2001-07-12 Cognis Deutschland Gmbh Waschmitteltabletten
DE19962859A1 (de) * 1999-12-24 2001-07-12 Cognis Deutschland Gmbh Feste Waschmittel
DE10002009A1 (de) * 2000-01-19 2001-07-26 Cognis Deutschland Gmbh Tensidgranulate
DE10003124A1 (de) 2000-01-26 2001-08-09 Cognis Deutschland Gmbh Verfahren zur Herstellung von Tensidgranulaten
DE10004677A1 (de) * 2000-02-03 2001-08-09 Cognis Deutschland Gmbh Tensidmischung mit Fettalkoholalkoxylaten aus pflanzlichen Rohstoffen
DE10005017A1 (de) * 2000-02-04 2001-08-09 Cognis Deutschland Gmbh Duftstofftabletten
DE10012949A1 (de) * 2000-03-16 2001-09-27 Henkel Kgaa Kieselsäureester-Mischungen
DE10019344A1 (de) 2000-04-18 2001-11-08 Cognis Deutschland Gmbh Wasch- und Reinigungsmittel
DE10019405A1 (de) 2000-04-19 2001-10-25 Cognis Deutschland Gmbh Verfahren zur Herstellung von Waschmittelgranulaten
DE10031620A1 (de) 2000-06-29 2002-01-10 Cognis Deutschland Gmbh Flüssigwaschmittel
DE10038845A1 (de) * 2000-08-04 2002-02-21 Henkel Kgaa Teilchenförmig konfektionierte Acetonitril-Derivate als Bleichaktivatoren in festen Waschmitteln
DE10044472A1 (de) 2000-09-08 2002-03-21 Cognis Deutschland Gmbh Waschmittel
DE10044471A1 (de) 2000-09-08 2002-03-21 Cognis Deutschland Gmbh Waschmittel
DE10046251A1 (de) 2000-09-19 2002-03-28 Cognis Deutschland Gmbh Wasch- und Reinigungsmittel auf Basis von Alkyl- und/oder Alkenyloligoglycosiden und Fettalkoholen
DE10058645A1 (de) 2000-11-25 2002-05-29 Clariant Gmbh Verwendung von cyclischen Zuckerketonen als Katalysatoren für Persauerstoffverbindungen
DE10064985A1 (de) 2000-12-23 2002-07-11 Henkel Kgaa Wasch- und Reinigungsmittelformkörper mit Beschichtung
DE10102248A1 (de) 2001-01-19 2002-07-25 Clariant Gmbh Verwendung von Übergangsmetallkomplexen mit Oxim-Liganden als Bleichkatalysatoren
DE10105801B4 (de) * 2001-02-07 2004-07-08 Henkel Kgaa Wasch- und Reinigungsmittel umfassend feine Mikropartikel mit Reinigungsmittelbestandteilen
DE10113334A1 (de) * 2001-03-20 2002-09-26 Cognis Deutschland Gmbh Quartäre Tenside
DE10118270A1 (de) * 2001-04-12 2002-10-17 Cognis Deutschland Gmbh Wasch- und Reinigungsmittelformittelkörper mit verbesserten Zerfallseigenschaften
CN1575308B (zh) 2001-10-22 2010-04-28 汉高两合股份公司 对棉有活性、具有去污能力的以氨基甲酸酯为基础的聚合物
DE10163856A1 (de) 2001-12-22 2003-07-10 Cognis Deutschland Gmbh Hydroxymischether und Polymere in Form von festen Mitteln als Vorcompound für Wasch-, Spül- und Reinigungsmittel
US20050119151A1 (en) * 2002-04-10 2005-06-02 Konstanze Mayer Textile cleaning agent which is gentle on textiles
US7448556B2 (en) * 2002-08-16 2008-11-11 Henkel Kgaa Dispenser bottle for at least two active fluids
DE10257387A1 (de) * 2002-12-06 2004-06-24 Henkel Kgaa Mehrkomponenten-Flüssigwaschmittel
US20050215449A1 (en) * 2002-11-20 2005-09-29 Josef Penninger Textile care product
DE10257389A1 (de) 2002-12-06 2004-06-24 Henkel Kgaa Flüssiges saures Waschmittel
DE10351321A1 (de) * 2003-02-10 2004-08-26 Henkel Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch eine Kombination von Cellulosderivaten
ES2285421T3 (es) 2003-02-10 2007-11-16 Henkel Kommanditgesellschaft Auf Aktien Agente de lavado o de limpieza, que continen un agente de blanqueo, con sistema adyuvante, soluble en agua, y un derivado de la celulosa con capacidad para el desprendimiento de la suciedad.
DE10351325A1 (de) * 2003-02-10 2004-08-26 Henkel Kgaa Wasch- oder Reinigungsmittel mit wasserlöslichem Buildersystem und schmutzablösevermögendem Cellulosederivat
ATE350447T1 (de) * 2003-02-10 2007-01-15 Henkel Kgaa Erhöhung der wasseraufnahmefähigkeit von textilien
WO2004069972A1 (de) * 2003-02-10 2004-08-19 Henkel Kommanditgesellschaft Auf Aktien Bleichmittelhaltiges waschmittel mit baumwollaktivem schmutzablösevermögendem cellulosederivat
JP2006517245A (ja) * 2003-02-10 2006-07-20 ヘンケル・コマンディットゲゼルシャフト・アウフ・アクチエン 発泡調節剤としてのセルロース誘導体の使用
ATE363525T1 (de) * 2003-02-10 2007-06-15 Henkel Kgaa Verstärkung der reinigungsleistung von waschmitteln durch cellulosederivat und hygroskopisches polymer
DE10311852A1 (de) * 2003-03-17 2004-10-14 Henkel Kgaa Textilbehandlungsmittel
DE10338070A1 (de) * 2003-08-19 2005-03-17 Henkel Kgaa Auf Substratoberflächen aufziehende Mittel
CN1886427B (zh) * 2003-11-28 2012-05-23 伊士曼化工公司 纤维素共聚体和氧化方法
DE102004007860A1 (de) * 2004-02-17 2005-09-15 Henkel Kgaa Spenderflasche für Flüssigwaschmittel, die aus mindestens zwei Teilzusammensetzungen bestehen
DE102004016497B4 (de) * 2004-04-03 2007-04-26 Henkel Kgaa Verfahren zur Herstellung von Granulaten und deren Einsatz in Wasch- und/oder Reinigungsmitteln
DE102004018790B4 (de) * 2004-04-15 2010-05-06 Henkel Ag & Co. Kgaa Wasserlöslich umhüllte Bleichmittelteilchen
DE102004018789A1 (de) * 2004-04-15 2005-11-10 Henkel Kgaa Flüssiges Wasch- oder Reinigungsmittel mit wasserlöslich umhülltem Bleichmittel
DE102004020015A1 (de) * 2004-04-21 2005-11-10 Henkel Kgaa Textilpflegemittel
DE102004021732A1 (de) * 2004-04-30 2005-11-24 Henkel Kgaa Textilplegemittel mit amingruppenhaltigem Celluloseether
DE102004024816A1 (de) * 2004-05-17 2005-12-15 Henkel Kgaa Bleichverstärkerkombination für den Einsatz in Wasch- und Reinigungsmitteln
EP1747259A1 (de) * 2004-05-17 2007-01-31 Henkel Kommanditgesellschaft auf Aktien Waschmittel mit gegebenenfalls in situ erzeugtem bleichverstärkendem übergangsmetallkomplex
FR2873700B1 (fr) * 2004-07-29 2006-11-24 Centre Nat Rech Scient Cnrse Procede d'oxydation controlee de polysaccharides
DE102004054620A1 (de) * 2004-11-11 2006-06-08 Henkel Kgaa Geranonitril-Substitut
US20060264346A1 (en) * 2005-05-19 2006-11-23 Sullivan Mary K Timed-release cleansing and/or treatment formulation and method for making and using the same
DE102005026522B4 (de) 2005-06-08 2007-04-05 Henkel Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch Polymer
DE102005026544A1 (de) 2005-06-08 2006-12-14 Henkel Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch Polymer
DE102005039580A1 (de) 2005-08-19 2007-02-22 Henkel Kgaa Farbschützendes Waschmittel
DE102005062268A1 (de) 2005-12-24 2007-08-02 Henkel Kgaa Pulverförmige Stylingmittel und deren Spendersysteme
DE102006011087A1 (de) * 2006-03-08 2007-09-13 Henkel Kgaa Aminoalkyl-Gruppen enthaltende Wirkstoffträger auf Silizium-Basis
CZ298350B6 (cs) * 2006-03-10 2007-09-05 Synthesia, A.S. Zpusob prípravy bioresorbovatelné oxidované celulózy
DE102006012018B3 (de) * 2006-03-14 2007-11-15 Henkel Kgaa Farbschützendes Waschmittel
WO2007115168A2 (en) 2006-03-31 2007-10-11 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of eg5 gene
DE102006018344A1 (de) * 2006-04-19 2007-10-31 Henkel Kgaa Umhüllte Imidoperoxocarbonsäureteilchen
WO2007134614A1 (de) * 2006-05-18 2007-11-29 Henkel Ag & Co. Kgaa Farbschützendes waschmittel
US7812150B2 (en) 2006-05-19 2010-10-12 Alnylam Pharmaceuticals, Inc. RNAi modulation of Aha and therapeutic uses thereof
WO2007137220A2 (en) 2006-05-22 2007-11-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of ikk-b gene
AP3018A (en) 2007-03-29 2014-10-31 Alnylam Pharmaceuticals Inc Compositions and methods for inhibiting expressionof a gene from the ebola
DE102007016391A1 (de) 2007-04-03 2008-10-09 Henkel Ag & Co. Kgaa Farbschützendes Wasch- oder Reinigungsmittel
AU2008335202A1 (en) 2007-12-10 2009-06-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of Factor VII gene
SG188121A1 (en) 2008-03-05 2013-03-28 Alnylam Pharmaceuticals Inc Compositions and methods for inhibiting expression of eg5 and vegf genes
JP2009263641A (ja) * 2008-03-31 2009-11-12 Kao Corp ポリウロン酸塩の製造方法
JP5544107B2 (ja) * 2008-03-31 2014-07-09 花王株式会社 高分子ビルダー
EP2261262A4 (en) * 2008-03-31 2013-07-10 Kao Corp METHOD FOR PRODUCING POLYURONATE
US9376648B2 (en) * 2008-04-07 2016-06-28 The Procter & Gamble Company Foam manipulation compositions containing fine particles
EP3208337A1 (en) 2008-09-02 2017-08-23 Alnylam Pharmaceuticals, Inc. Compositions for combined inhibition of mutant egfr and il-6 expression
EP3584320A1 (en) 2008-09-25 2019-12-25 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
DK2344639T3 (en) 2008-10-20 2015-07-27 Alnylam Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETINE
CA2746514C (en) 2008-12-10 2018-11-27 Alnylam Pharmaceuticals, Inc. Gnaq targeted dsrna compositions and methods for inhibiting expression
FR2940293B1 (fr) 2008-12-18 2013-12-20 Kalys Nouveau procede d'hydrolyse controlee des polysaccharides.
WO2010099341A1 (en) 2009-02-26 2010-09-02 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of mig-12 gene
EP2406376A1 (en) 2009-03-12 2012-01-18 Alnylam Pharmaceuticals, Inc. LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES
AP3574A (en) 2009-08-14 2016-02-08 Alnylam Pharmaceuticals Inc Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus
ES2893199T3 (es) 2010-03-29 2022-02-08 Alnylam Pharmaceuticals Inc Terapia de ARNbc para amiloidosis ocular relacionada con transtiretina (TTR)
JP2013523162A (ja) 2010-04-06 2013-06-17 アルナイラム ファーマシューティカルズ， インコーポレイテッド Ｃｄ２７４／ｐｄ−ｌ１遺伝子の発現を阻害するための組成物および方法
AU2011261434B2 (en) 2010-06-02 2015-11-26 Alnylam Pharmaceuticals, Inc. Compositions and methods directed to treating liver fibrosis
WO2012064824A1 (en) 2010-11-09 2012-05-18 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes
US9127275B2 (en) 2010-12-10 2015-09-08 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of klf-1 and bcl11a genes
WO2012078967A2 (en) 2010-12-10 2012-06-14 Alnylam Pharmaceuticals, Inc. Compositions and methods for increasing erythropoietin (epo) production
DE102011010818A1 (de) 2011-02-10 2012-08-16 Clariant International Ltd. Verwendung von Übergangsmetallkomplexen als Bleichkatalysatoren in Wasch- und Reinigungsmitteln
KR102365961B1 (ko) 2011-03-29 2022-02-23 알닐람 파마슈티칼스 인코포레이티드 Tmprss6 유전자의 발현을 억제하기 위한 조성물 및 방법
JP2014511694A (ja) 2011-04-03 2014-05-19 ザ ジェネラル ホスピタル コーポレーション ドゥーイング ビジネス アズ マサチューセッツ ジェネラル ホスピタル 修飾型ｒｎａ（ｍｏｄ−ｒｎａ）を使用する効率的なインビボタンパク質発現
KR20230084331A (ko) 2011-06-21 2023-06-12 알닐람 파마슈티칼스 인코포레이티드 아포리포단백질 c-iii(apoc3) 유전자의 발현 억제를 위한 조성물 및 방법
MX360782B (es) 2011-06-21 2018-11-16 Alnylam Pharmaceuticals Inc Composiciones de arni similares a angiopoyetina 3 (angptl3) y metodos para su uso.
EP3388068A1 (en) 2011-06-21 2018-10-17 Alnylam Pharmaceuticals, Inc. Composition and methods for inhibition of expression of protein c (proc) genes
EP2723390B1 (en) 2011-06-23 2017-12-27 Alnylam Pharmaceuticals, Inc. Serpina1 sirnas: compositions of matter and methods of treatment
WO2013019857A2 (en) 2011-08-01 2013-02-07 Alnylam Pharmaceuticals, Inc. Method for improving the success rate of hematopoietic stem cell transplants
WO2013059740A1 (en) 2011-10-21 2013-04-25 Foundation Medicine, Inc. Novel alk and ntrk1 fusion molecules and uses thereof
US9133461B2 (en) 2012-04-10 2015-09-15 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the ALAS1 gene
US9127274B2 (en) 2012-04-26 2015-09-08 Alnylam Pharmaceuticals, Inc. Serpinc1 iRNA compositions and methods of use thereof
US20150148531A1 (en) * 2012-05-15 2015-05-28 Teknologian Tutkimuskeskus Vtt Method for the manufacture of carbonyl derivatives of polysaccharides
ES2949394T3 (es) 2012-11-05 2023-09-28 Found Medicine Inc Moléculas de fusión novedosas y usos de las mismas
WO2014071358A2 (en) 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel ntrk1 fusion molecules and uses thereof
CA3150658A1 (en) 2013-01-18 2014-07-24 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
WO2014130922A1 (en) 2013-02-25 2014-08-28 Trustees Of Boston University Compositions and methods for treating fungal infections
SG10201912286TA (en) 2013-03-14 2020-02-27 Alnylam Pharmaceuticals Inc COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
EP2981617B1 (en) 2013-04-04 2023-07-05 President and Fellows of Harvard College Therapeutic uses of genome editing with crispr/cas systems
AP2015008862A0 (en) 2013-05-22 2015-11-30 Alnylam Pharmaceuticals Inc Tmprss6 irna compositions and methods of use thereof
CN113018307A (zh) 2013-05-22 2021-06-25 阿尔尼拉姆医药品有限公司 SERPINA1 iRNA组合物及其使用方法
US20160113911A1 (en) 2013-06-06 2016-04-28 The General Hospital Corporation Methods and compositions for the treatment of cancer
AU2014317975B2 (en) * 2013-09-06 2017-10-26 Dow Global Technologies Llc Metal oxide particles with uniform multilayer polymer coatings
EP3052626A1 (en) 2013-10-02 2016-08-10 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the lect2 gene
US10119143B2 (en) 2013-10-04 2018-11-06 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the ALAS1 gene
US10053692B2 (en) 2013-10-21 2018-08-21 The General Hospital Corporation Methods relating to circulating tumor cell clusters and the treatment of cancer
DE102013019269A1 (de) 2013-11-15 2015-06-03 Weylchem Switzerland Ag Geschirrspülmittel sowie dessen Verwendung
MX382900B (es) 2013-12-12 2025-03-13 Alnylam Pharmaceuticals Inc COMPOSICIONES DE ÁCIDO RIBONUCLEICO DE INTERFERENCIA (ARNi) CONTRA EL COMPONENTE DEL COMPLEMENTO Y MÉTODOS PARA SU USO.
DE102013226098A1 (de) 2013-12-16 2015-06-18 Henkel Kgaa Silylenolether von Riechstoffketonen oder -aldehyden
DE102013226216A1 (de) 2013-12-17 2015-06-18 Henkel Ag & Co. Kgaa Michael-Systeme für die Duftstoff-Stabilisierung
DE102013226602A1 (de) 2013-12-19 2015-06-25 Henkel Ag & Co. Kgaa Verwendung von CNGA2-Agonisten zur Verstärkung der olfaktorischen Wirkung eines Riechstoffs
CN106456694B (zh) 2013-12-20 2020-06-30 通用医疗公司 与循环肿瘤细胞相关的方法和测定法
AU2015217301A1 (en) 2014-02-11 2016-08-25 Alnylam Pharmaceuticals, Inc. Ketohexokinase (KHK) iRNA compositions and methods of use thereof
WO2015124189A1 (de) 2014-02-20 2015-08-27 Henkel Ag & Co. Kgaa Wasch- oder reinigungsmittel mit verbessertem schaumverhalten unter hoher schmutzbelastung
TW201607559A (zh) 2014-05-12 2016-03-01 阿尼拉製藥公司 治療ｓｅｒｐｉｎｃ１相關疾患之方法和組成物
CN106574268B (zh) 2014-05-22 2021-02-05 阿尔尼拉姆医药品有限公司 血管紧张素原（AGT）iRNA组合物及其使用方法
JP2017518307A (ja) 2014-06-02 2017-07-06 チルドレンズ メディカル センター コーポレーション 免疫調節のための方法および組成物
EP2963103A1 (de) 2014-07-04 2016-01-06 Henkel AG & Co. KGaA pH-sensitive Nanokapseln
JP2017526367A (ja) 2014-08-29 2017-09-14 チルドレンズ メディカル センター コーポレーション 癌の処置のための方法および組成物
PL3185957T3 (pl) 2014-08-29 2022-11-14 Alnylam Pharmaceuticals, Inc. Patisiran do zastosowania w leczeniu amyloidozy związanej z transtyretyną
WO2016040589A1 (en) 2014-09-12 2016-03-17 Alnylam Pharmaceuticals, Inc. Polynucleotide agents targeting complement component c5 and methods of use thereof
TWI755351B (zh) 2014-10-10 2022-02-21 美商艾爾妮蘭製藥公司 用於抑制ｈａｏ１（羥酸氧化酶１（乙醇酸鹽氧化酶））基因表現的組合物及方法
EP3207138B1 (en) 2014-10-17 2020-07-15 Alnylam Pharmaceuticals, Inc. Polynucleotide agents targeting aminolevulinic acid synthase-1 (alas1) and uses thereof
EP3904519A1 (en) 2014-10-30 2021-11-03 Genzyme Corporation Polynucleotide agents targeting serpinc1 (at3) and methods of use thereof
HRP20192177T1 (hr) 2014-11-10 2020-02-21 Alnylam Pharmaceuticals, Inc. Rnai pripravci za virus hepatitisa b (hbv) i postupci njihove upotrebe
CN113846101A (zh) 2014-11-17 2021-12-28 阿尔尼拉姆医药品有限公司 载脂蛋白C3（APOC3）iRNA组合物及其使用方法
JP2018510621A (ja) 2015-02-13 2018-04-19 アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． パタチン様ホスホリパーゼドメイン含有３（ＰＮＰＬＡ３）ｉＲＮＡ組成物およびその使用方法
DE102015002877B4 (de) 2015-03-09 2024-09-12 Henkel Ag & Co. Kgaa Wasch- oder reinigungsaktive Extrudate, deren Herstellung und Verwendung in granularen Wasch- oder Reinigungsmitteln
CN115537396A (zh) 2015-03-27 2022-12-30 哈佛学院校长同事会 经过修饰的t细胞及其制备和使用方法
WO2016164746A1 (en) 2015-04-08 2016-10-13 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the lect2 gene
EP3307316A1 (en) 2015-06-12 2018-04-18 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions and methods of use thereof
WO2016205323A1 (en) 2015-06-18 2016-12-22 Alnylam Pharmaceuticals, Inc. Polynucleotde agents targeting hydroxyacid oxidase (glycolate oxidase, hao1) and methods of use thereof
WO2016209862A1 (en) 2015-06-23 2016-12-29 Alnylam Pharmaceuticals, Inc. Glucokinase (gck) irna compositions and methods of use thereof
WO2017011286A1 (en) 2015-07-10 2017-01-19 Alnylam Pharmaceuticals, Inc. Insulin-like growth factor binding protein, acid labile subunit (igfals) and insulin-like growth factor 1 (igf-1) irna compositions and methods of use thereof
EP4393495A3 (en) 2015-09-02 2024-09-25 Alnylam Pharmaceuticals, Inc. Programmed cell death 1 ligand 1 (pd-l1) irna compositions and methods of use thereof
IL259795B2 (en) 2015-12-07 2024-04-01 Genzyme Corp Methods and compositions for treating a serpinc1-associated disorder
DE102015016402A1 (de) 2015-12-18 2017-06-22 Weylchem Wiesbaden Gmbh Feinteilige Bleichkatalysatoren, Verfahren zu deren Herstellung und deren Verwendung
DE102016201295A1 (de) 2016-01-28 2017-08-03 Henkel Ag & Co. Kgaa C8-10-Alkylamidoalkylbetain als Antiknitterwirkstoff
MA45295A (fr) 2016-04-19 2019-02-27 Alnylam Pharmaceuticals Inc Composition d'arni de protéine de liaison de lipoprotéines haute densité (hdlbp/vigiline) et procédés pour les utiliser
EP3469083A1 (en) 2016-06-10 2019-04-17 Alnylam Pharmaceuticals, Inc. COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
WO2018112320A1 (en) 2016-12-16 2018-06-21 Alnylam Pharmaceuticals, Inc. Methods for treating or preventing ttr-associated diseases using transthyretin (ttr) irna compositions
DE102017206013A1 (de) 2017-04-07 2018-10-11 Henkel Ag & Co. Kgaa Wasch- oder Reinigungsmittel mit verbessertem Schaumverhalten
CN118384268A (zh) 2017-04-18 2024-07-26 阿尔尼拉姆医药品有限公司 具有乙肝病毒（hbv）感染的受试者的治疗方法
CN111093771A (zh) 2017-07-10 2020-05-01 建新公司 在患有血友病的受试者中治疗出血事件的方法和组合物
EP3652317A1 (en) 2017-07-13 2020-05-20 Alnylam Pharmaceuticals, Inc. Lactate dehydrogenase a (ldha) irna compositions and methods of use thereof
US11806360B2 (en) 2017-09-19 2023-11-07 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating transthyretin (TTR) mediated amyloidosis
DE102017123282A1 (de) 2017-10-06 2019-04-11 Henkel Ag & Co. Kgaa Hydrolyselabile Silylenolether von Riechstoffketonen oder -aldehyden
DE102017124612A1 (de) 2017-10-20 2019-04-25 Henkel Ag & Co. Kgaa Hydrolyselabile Dienolsilylether von Riechstoffketonen oder -aldehyden
DE102017124611A1 (de) 2017-10-20 2019-04-25 Henkel Ag & Co. Kgaa Thermolabile Duftspeicherstoffe von Riechstoffketonen
SG11202002940QA (en) 2017-11-01 2020-04-29 Alnylam Pharmaceuticals Inc Complement component c3 irna compositions and methods of use thereof
EP3710587A1 (en) 2017-11-16 2020-09-23 Alnylam Pharmaceuticals, Inc. Kisspeptin 1 (kiss1) irna compositions and methods of use thereof
EP3714054A1 (en) 2017-11-20 2020-09-30 Alnylam Pharmaceuticals, Inc. Serum amyloid p component (apcs) irna compositions and methods of use thereof
DE102017127776A1 (de) 2017-11-24 2019-05-29 Henkel Ag & Co. Kgaa Hydrolyselabile Heterocyclen von Riechstoffketonen oder -aldehyden
JP2021508491A (ja) 2017-12-18 2021-03-11 アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 高移動度グループボックス−１（ＨＭＧＢ１）ｉＲＮＡ組成物及びその使用方法
TWI851574B (zh) 2018-05-14 2024-08-11 美商阿尼拉製藥公司 血管收縮素原（ＡＧＴ）ｉＲＮＡ組成物及其使用方法
EP3578629B1 (de) 2018-06-07 2023-06-07 Henkel AG & Co. KGaA Verfahren zur herstellung eines flüssigen wasch- oder reinigungsmittels mit einer konservierungsmittelfreien farbstofflösung
KR102918289B1 (ko) 2018-08-13 2026-01-28 알닐람 파마슈티칼스 인코포레이티드 B형 간염 바이러스 (HBV) dsRNA 제제 조성물 및 이의 사용 방법
EP3837367A1 (en) 2018-08-16 2021-06-23 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of the lect2 gene
CN118667811A (zh) 2018-09-18 2024-09-20 阿尔尼拉姆医药品有限公司 己酮糖激酶(KHK)iRNA组合物及其使用方法
US10913951B2 (en) 2018-10-31 2021-02-09 University of Pittsburgh—of the Commonwealth System of Higher Education Silencing of HNF4A-P2 isoforms with siRNA to improve hepatocyte function in liver failure
US11155771B2 (en) 2018-11-09 2021-10-26 Henkel Ag & Co. Kgaa Method for preparing a liquid washing or cleaning agent using a preservative-free dye solution
US12485136B2 (en) 2018-12-03 2025-12-02 Takeda Pharmaceuticals U.S.A., Inc. Methods for the treatment of trinucleotide repeat expansion disorders associated with MLH3 activity
PL4285929T3 (pl) 2018-12-20 2026-03-23 Humabs Biomed Sa Terapia skojarzona hbv
CN113631709A (zh) 2018-12-20 2021-11-09 普拉克西斯精密药物股份有限公司 用于治疗kcnt1相关病症的组合物和方法
EP3911335A1 (en) 2019-01-16 2021-11-24 Genzyme Corporation Serpinc1 irna compositions and methods of use thereof
CA3139325A1 (en) 2019-05-13 2020-11-19 Vir Biotechnology, Inc. Compositions and methods for treating hepatitis b virus (hbv) infection
EP4007812A1 (en) 2019-08-01 2022-06-08 Alnylam Pharmaceuticals, Inc. Serpin family f member 2 (serpinf2) irna compositions and methods of use thereof
WO2021022108A2 (en) 2019-08-01 2021-02-04 Alnylam Pharmaceuticals, Inc. CARBOXYPEPTIDASE B2 (CPB2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
WO2021030522A1 (en) 2019-08-13 2021-02-18 Alnylam Pharmaceuticals, Inc. SMALL RIBOSOMAL PROTEIN SUBUNIT 25 (RPS25) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
CN114616331B (zh) 2019-09-03 2024-10-22 阿尔尼拉姆医药品有限公司 抑制lect2基因表达的组合物和方法
WO2021067747A1 (en) 2019-10-04 2021-04-08 Alnylam Pharmaceuticals, Inc. Compositions and methods for silencing ugt1a1 gene expression
EP4045652A1 (en) 2019-10-18 2022-08-24 Alnylam Pharmaceuticals, Inc. Solute carrier family member irna compositions and methods of use thereof
JP7676377B2 (ja) 2019-10-22 2025-05-14 アルナイラム ファーマシューティカルズ， インコーポレイテッド 補体成分Ｃ３ ｉＲＮＡ組成物およびその使用方法
US20230040920A1 (en) 2019-11-01 2023-02-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for silencing dnajb1-prkaca fusion gene expression
CN119499394A (zh) 2019-11-01 2025-02-25 阿尔尼拉姆医药品有限公司 亨廷顿（HTT）iRNA药剂组合物及其使用方法
WO2021096763A1 (en) 2019-11-13 2021-05-20 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating an angiotensinogen- (agt-) associated disorder
EP4061945A1 (en) 2019-11-22 2022-09-28 Alnylam Pharmaceuticals, Inc. Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
CA3164599A1 (en) 2019-12-13 2021-06-17 Alnylam Pharmaceuticals, Inc. Human chromosome 9 open reading frame 72 (c9orf72) irna agent compositions and methods of use thereof
TW202138559A (zh) 2019-12-16 2021-10-16 美商阿尼拉製藥公司 含類ＰＡＴＡＴＩＮ磷脂酶結構域３（ＰＮＰＬＡ３）ｉＲＮＡ組成物及其使用方法
WO2021154941A1 (en) 2020-01-31 2021-08-05 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
MX2022009763A (es) 2020-02-10 2022-09-09 Alnylam Pharmaceuticals Inc Composiciones y metodos para silenciar la expresion del factor de crecimiento endotelial vascular a (vegf-a).
KR20220143106A (ko) 2020-02-18 2022-10-24 알닐람 파마슈티칼스 인코포레이티드 아포지질단백질 C3 (APOC3) iRNA 조성물 및 이의 사용 방법
WO2021178607A1 (en) 2020-03-05 2021-09-10 Alnylam Pharmaceuticals, Inc. Complement component c3 irna compositions and methods of use thereof for treating or preventing complement component c3-associated diseases
BR112022017822A2 (pt) 2020-03-06 2022-11-08 Alnylam Pharmaceuticals Inc Composições de irna de cetoexocinase (khk) e métodos de uso das mesmas
EP4121534A1 (en) 2020-03-18 2023-01-25 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating subjects having a heterozygous alanine-glyoxylate aminotransferase gene (agxt) variant
CN116209759A (zh) 2020-03-26 2023-06-02 阿尔尼拉姆医药品有限公司 冠状病毒iRNA组合物及其使用方法
US20230190785A1 (en) 2020-03-30 2023-06-22 Alnylam Pharmaceuticals, Inc. Compositions and methods for silencing dnajc15 gene expression
US12534731B2 (en) 2020-04-01 2026-01-27 Alnylam Pharmaceuticals, Inc. Alpha-2A adrenergic receptor (ADRA2A) iRNA agent compositions and methods of use thereof
MX2022012493A (es) 2020-04-06 2022-10-27 Alnylam Pharmaceuticals Inc Composiciones y metodos para el silenciamiento de la expresion de miocilina (myoc).
EP4133077A1 (en) 2020-04-07 2023-02-15 Alnylam Pharmaceuticals, Inc. Transmembrane serine protease 2 (tmprss2) irna compositions and methods of use thereof
WO2021206917A1 (en) 2020-04-07 2021-10-14 Alnylam Pharmaceuticals, Inc. ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
AU2021251754A1 (en) 2020-04-07 2022-11-03 Alnylam Pharmaceuticals, Inc. Compositions and methods for silencing SCN9A expression
AU2021263554A1 (en) 2020-04-27 2022-12-08 Alnylam Pharmaceuticals, Inc. Apolipoprotein E (APOE) iRNA agent compositions and methods of use thereof
KR20230017789A (ko) 2020-04-30 2023-02-06 알닐람 파마슈티칼스 인코포레이티드 보체 인자 B (CFB) iRNA 조성물 및 이의 사용 방법
EP4150086A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of leucine rich repeat kinase 2 (lrrk2)
WO2021231692A1 (en) 2020-05-15 2021-11-18 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of otoferlin (otof)
EP4150076A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of methyl-cpg binding protein 2 (mecp2)
EP4150089A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of retinoschisin 1 (rs1)
EP4150087A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of gap junction protein beta 2 (gjb2)
WO2021231675A1 (en) 2020-05-15 2021-11-18 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of argininosuccinate synthetase (ass1)
EP4150078A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of argininosuccinate lyase (asl)
EP4150077A1 (en) 2020-05-15 2023-03-22 Korro Bio, Inc. Methods and compositions for the adar-mediated editing of transmembrane channel-like protein 1 (tmc1)
WO2021237097A1 (en) 2020-05-21 2021-11-25 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting marc1 gene expression
CN115885042A (zh) 2020-05-22 2023-03-31 波涛生命科学有限公司 双链寡核苷酸组合物及其相关方法
AR122534A1 (es) 2020-06-03 2022-09-21 Triplet Therapeutics Inc Métodos para el tratamiento de los trastornos de expansión por repetición de nucleótidos asociados con la actividad de msh3
WO2021252557A1 (en) 2020-06-09 2021-12-16 Alnylam Pharmaceuticals, Inc. Rnai compositions and methods of use thereof for delivery by inhalation
WO2021252649A2 (en) 2020-06-09 2021-12-16 Alnylam Pharmaceuticals, Inc. Sirna compositions and methods for silencing gpam (glycerol-3-phosphate acyltransferase 1, mitochondrial) expression
BR112022024420A2 (pt) 2020-06-18 2023-01-17 Alnylam Pharmaceuticals Inc Composições de irna de xantina desidrogenase (xdh) e métodos de uso das mesmas
US20230242621A1 (en) 2020-06-24 2023-08-03 Vir Biotechnology, Inc. Engineered hepatitis b virus neutralizing antibodies and uses thereof
WO2022066847A1 (en) 2020-09-24 2022-03-31 Alnylam Pharmaceuticals, Inc. Dipeptidyl peptidase 4 (dpp4) irna compositions and methods of use thereof
EP4225917A1 (en) 2020-10-05 2023-08-16 Alnylam Pharmaceuticals, Inc. G protein-coupled receptor 75 (gpr75) irna compositions and methods of use thereof
WO2022087041A1 (en) 2020-10-21 2022-04-28 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating primary hyperoxaluria
WO2022087329A1 (en) 2020-10-23 2022-04-28 Alnylam Pharmaceuticals, Inc. Mucin 5b (muc5b) irna compositions and methods of use thereof
EP4244355A1 (en) 2020-11-13 2023-09-20 Alnylam Pharmaceuticals, Inc. Coagulation factor v (f5) irna compositions and methods of use thereof
EP4256053A1 (en) 2020-12-01 2023-10-11 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhibition of hao1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression
EP4259795A1 (en) 2020-12-08 2023-10-18 Alnylam Pharmaceuticals, Inc. Coagulation factor x (f10) irna compositions and methods of use thereof
AU2021409740A1 (en) 2020-12-23 2023-07-06 Flagship Pioneering Innovations Vi, Llc Compositions of modified trems and uses thereof
WO2022150260A1 (en) 2021-01-05 2022-07-14 Alnylam Pharmaceuticals, Inc. COMPLEMENT COMPONENT 9 (C9) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
IL304880A (en) 2021-02-12 2023-10-01 Alnylam Pharmaceuticals Inc Superoxide dismutase 1 (sod1) irna compositions and methods of use thereof for treating or preventing superoxide dismutase 1- (sod1-) associated neurodegenerative diseases
JP2024509783A (ja) 2021-02-25 2024-03-05 アルナイラム ファーマシューティカルズ， インコーポレイテッド プリオンタンパク質（ｐｒｎｐ）ｉｒｎａ組成物およびその使用方法
WO2022182574A1 (en) 2021-02-26 2022-09-01 Alnylam Pharmaceuticals, Inc. KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
JP2024508896A (ja) 2021-03-04 2024-02-28 アルナイラム ファーマシューティカルズ， インコーポレイテッド アンジオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびその使用方法
EP4305169A1 (en) 2021-03-12 2024-01-17 Alnylam Pharmaceuticals, Inc. Glycogen synthase kinase 3 alpha (gsk3a) irna compositions and methods of use thereof
BR112023019981A2 (pt) 2021-03-29 2023-12-12 Alnylam Pharmaceuticals Inc Composições do agente irna de huntingtina (htt) e métodos de uso das mesmas
EP4314293A1 (en) 2021-04-01 2024-02-07 Alnylam Pharmaceuticals, Inc. Proline dehydrogenase 2 (prodh2) irna compositions and methods of use thereof
TW202309280A (zh) 2021-04-26 2023-03-01 美商艾拉倫製藥股份有限公司 跨膜絲胺酸蛋白酶６（ＴＭＰＲＳＳ６）ｉＲＮＡ組成物及其使用方法
WO2022232343A1 (en) 2021-04-29 2022-11-03 Alnylam Pharmaceuticals, Inc. Signal transducer and activator of transcription factor 6 (stat6) irna compositions and methods of use thereof
EP4334448A1 (en) 2021-05-03 2024-03-13 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating transthyretin (ttr) mediated amyloidosis
EP4341401A1 (en) 2021-05-18 2024-03-27 Alnylam Pharmaceuticals, Inc. Sodium-glucose cotransporter-2 (sglt2) irna compositions and methods of use thereof
WO2022246023A1 (en) 2021-05-20 2022-11-24 Korro Bio, Inc. Methods and compositions for adar-mediated editing
WO2022256283A2 (en) 2021-06-01 2022-12-08 Korro Bio, Inc. Methods for restoring protein function using adar
JP2024522996A (ja) 2021-06-02 2024-06-25 アルナイラム ファーマシューティカルズ， インコーポレイテッド パタチン様ホスホリパーゼドメイン含有３（ＰＮＰＬＡ３）ｉＲＮＡ組成物およびその使用方法
WO2022256290A2 (en) 2021-06-04 2022-12-08 Alnylam Pharmaceuticals, Inc. HUMAN CHROMOSOME 9 OPEN READING FRAME 72 (C9ORF72) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
EP4351541A2 (en) 2021-06-08 2024-04-17 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating or preventing stargardt's disease and/or retinal binding protein 4 (rbp4)-associated disorders
JP2022191822A (ja) * 2021-06-16 2022-12-28 大日精化工業株式会社 酸化多糖及びその製造方法、並びに酸化多糖分散体
WO2023278410A1 (en) 2021-06-29 2023-01-05 Korro Bio, Inc. Methods and compositions for adar-mediated editing
US20230194709A9 (en) 2021-06-29 2023-06-22 Seagate Technology Llc Range information detection using coherent pulse sets with selected waveform characteristics
JP2024527304A (ja) 2021-06-30 2024-07-24 アルナイラム ファーマシューティカルズ， インコーポレイテッド アンジオテンシノーゲン（ａｇｔ）関連障害を治療するための方法および組成物
WO2023003805A1 (en) 2021-07-19 2023-01-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating subjects having or at risk of developing a non-primary hyperoxaluria disease or disorder
WO2023003995A1 (en) 2021-07-23 2023-01-26 Alnylam Pharmaceuticals, Inc. Beta-catenin (ctnnb1) irna compositions and methods of use thereof
JP2024529437A (ja) 2021-07-29 2024-08-06 アルナイラム ファーマシューティカルズ， インコーポレイテッド ３－ヒドロキシ－３－メチルグリタル－ＣＯＡレダクターゼ（ＨＭＧＣＲ）ｉＲＮＡ組成物およびその使用方法
IL310244A (en) 2021-08-03 2024-03-01 Alnylam Pharmaceuticals Inc Transthyretin (TTR) IRNA compositions and methods of using them
MX2024001445A (es) 2021-08-04 2024-02-27 Alnylam Pharmaceuticals Inc Composiciones de acido ribonucleico de interferencia (arni) y metodos para silenciar el angiotensinogeno (agt).
JP2024534766A (ja) 2021-08-13 2024-09-26 アルナイラム ファーマシューティカルズ， インコーポレイテッド 第ＸＩＩ因子（Ｆ１２）ｉＲＮＡ組成物およびその使用方法
AU2022339821A1 (en) 2021-08-31 2024-03-07 Alnylam Pharmaceuticals, Inc. Cell death-inducing dffa-like effector b (cideb) irna compositions and methods of use thereof
WO2023044370A2 (en) 2021-09-17 2023-03-23 Alnylam Pharmaceuticals, Inc. Irna compositions and methods for silencing complement component 3 (c3)
AU2022345881A1 (en) 2021-09-20 2024-03-21 Alnylam Pharmaceuticals, Inc. Inhibin subunit beta e (inhbe) modulator compositions and methods of use thereof
MX2024003519A (es) 2021-09-24 2024-04-01 Alnylam Pharmaceuticals Inc Composiciones de agentes de acido ribonucleico de interferencia (arni) de proteina tau asociada a microtubulos (mapt) y sus metodos de uso.
CA3234835A1 (en) 2021-10-22 2023-04-27 Korro Bio, Inc. Methods and compositions for disrupting nrf2-keap1 protein interaction by adar mediated rna editing
TW202334418A (zh) 2021-10-29 2023-09-01 美商艾拉倫製藥股份有限公司 杭丁頓（ＨＴＴ）ｉＲＮＡ劑組成物及其使用方法
JP2024541989A (ja) 2021-10-29 2024-11-13 アルナイラム ファーマシューティカルズ， インコーポレイテッド 補体因子Ｂ（ＣＦＢ）ｉＲＮＡ組成物およびその使用方法
WO2023141314A2 (en) 2022-01-24 2023-07-27 Alnylam Pharmaceuticals, Inc. Heparin sulfate biosynthesis pathway enzyme irna agent compositions and methods of use thereof
EP4242287A1 (en) 2022-03-07 2023-09-13 Henkel AG & Co. KGaA Laundry detergent
JP2025527531A (ja) 2022-08-18 2025-08-22 アルナイラム ファーマシューティカルズ， インコーポレイテッド ユニバーサル非標的ｓｉｒｎａ組成物およびその使用方法
EP4569113A1 (en) 2022-09-15 2025-06-18 Regeneron Pharmaceuticals, Inc. 17b-hydroxysteroid dehydrogenase type 13 (hsd17b13) irna compositions and methods of use thereof
TW202449152A (zh) 2023-02-09 2024-12-16 美商艾拉倫製藥股份有限公司 Ｒｅｖｅｒｓｉｒ分子及其使用方法
WO2024220746A2 (en) 2023-04-21 2024-10-24 Flagship Pioneering Innovations Vii, Llc Rnai agents targeting fatty acid synthase and related methods
DE202023000933U1 (de) 2023-04-27 2023-05-08 WeylChem Performance Products GmbH Geschirrspülmittel sowie dessen Verwendung
AU2024287308A1 (en) 2023-07-13 2025-12-18 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025024493A1 (en) 2023-07-25 2025-01-30 Flagship Pioneering Innovations Vii, Llc Cas endonucleases and related methods
WO2025024486A2 (en) 2023-07-25 2025-01-30 Flagship Pioneering Innovations Vii, Llc Cas endonucleases and related methods
CN121605192A (zh) 2023-08-04 2026-03-03 阿尔尼拉姆医药品有限公司 用于治疗ctnnb1-相关病症的方法和组合物
WO2025072331A1 (en) 2023-09-26 2025-04-03 Flagship Pioneering Innovations Vii, Llc Cas nucleases and related methods
WO2025072713A1 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Polymyxins for delivery of agents to the kidney
WO2025072672A2 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Slc6a19-targeting modulatory nucleic acid agents
WO2025072699A1 (en) 2023-09-27 2025-04-03 Judo Bio, Inc. Aminoglycosides for delivery of agents to the kidney
WO2025076031A2 (en) 2023-10-03 2025-04-10 Alnylam Pharmaceuticals, Inc. Peritoneal macrophages comprising a nanoparticle encapsulating a nucleic acid molecule and methods of use thereof
WO2025117877A2 (en) 2023-12-01 2025-06-05 Flagship Pioneering Innovations Vii, Llc Cas nucleases and related methods
WO2025128799A1 (en) 2023-12-12 2025-06-19 Korro Bio, Inc. Double-stranded rna-editing oligonucleotides and uses thereof
US20250263702A1 (en) 2024-02-19 2025-08-21 Flagship Pioneering Innovations Vii, Llc Rnai agents targeting cideb and related methods
WO2025199231A2 (en) 2024-03-20 2025-09-25 Vertex Pharmaceuticals Incorporated Mucin-5b (muc5b) targeted sirna and antisense oligonucleotides and methods of use thereof
WO2025217275A2 (en) 2024-04-10 2025-10-16 Flagship Pioneering Innovations Vii, Llc Immune cell targeted compositions and related methods
WO2025259747A2 (en) 2024-06-12 2025-12-18 Alnylam Pharmaceuticals, Inc. Dystrophy myotonic protein kinase (dmpk) irna compositions and methods of use thereof
WO2025259743A1 (en) 2024-06-12 2025-12-18 Alnylam Pharmaceuticals, Inc. Dual conjugate compounds for extrahepatic delivery
WO2026055461A1 (en) 2024-09-05 2026-03-12 Aperture Therapeutics, Inc. Antibody oligonucleotide conjugates comprising an antisense polynucleotide agent conjugated to a cd33 antibody and methods of use thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2472590A (en) * 1945-03-02 1949-06-07 Eastman Kodak Co Oxidation of starch with nitrogen dioxide
DE941282C (de) * 1953-04-19 1956-04-05 Harry Pauling Dipl Ing Verfahren und Vorrichtung zum Oxydieren von Cellulose oder cellulosehaltigen Stoffenmittels Stickstoffdioxyd
BE527849A (es) * 1953-04-19
US3478752A (en) * 1968-07-16 1969-11-18 Sutton Res Corp Cellulosic smoking product and method in the preparation of same
US3665000A (en) * 1969-12-23 1972-05-23 Fmc Corp Tricarboxystarch derivatives
US3740339A (en) * 1971-06-28 1973-06-19 Int Paper Co Detergent formulation containing cured 6-carboxy cellulose as a sequestrant
AT330930B (de) * 1973-04-13 1976-07-26 Henkel & Cie Gmbh Verfahren zur herstellung von festen, schuttfahigen wasch- oder reinigungsmitteln mit einem gehalt an calcium bindenden substanzen
DE2436843A1 (de) * 1974-07-31 1976-02-12 Akzo Gmbh Stoffgemisch aus oxydationsprodukten von cellulose, hemicellulosen und lignin
JPS51149388A (en) * 1975-06-17 1976-12-22 Sumitomo Chem Co Ltd A process for preparing the carboxylated pullulan
US4333484A (en) * 1978-08-02 1982-06-08 Philip Morris Incorporated Modified cellulosic smoking material and method for its preparation
DE2918441A1 (de) * 1979-05-08 1980-11-13 Krupp Gmbh Verfahren zum lichtbogenschweissen und zuschlagstoff zum durchfuehren des verfahrens
SE421938B (sv) * 1980-06-05 1982-02-08 Mo Och Domsjoe Ab Forfarande for behandling av cellulosamassa med kveveoxider fore syrgasblekning
US4347056A (en) * 1981-02-17 1982-08-31 Yasnitsky Boris G Method of making absorbable surgical threads
SE451149B (sv) * 1983-01-26 1987-09-07 Mo Och Domsjoe Ab Apparatur for kontinuerlig behandling av vatteninnehallande lignocellulosamaterial med kveveoxid och syre
DE3303153A1 (de) * 1983-01-31 1984-08-02 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von hochsubstituierten carboxyalkylcellulosen und deren mischethern
US4531000A (en) * 1984-10-05 1985-07-23 British Columbia Research Council Processes for the preparation of branched, water soluble cellulose products
FR2653442A1 (fr) * 1989-10-23 1991-04-26 Roquette Freres Composition pour produits de lavage, son procede de preparation et produit de lavage la contenant.
FR2659979B1 (fr) * 1990-03-23 1994-04-29 Roquette Freres Produit de lavage a teneur reduite ou nulle en phosphates.
US5180398A (en) * 1990-12-20 1993-01-19 Johnson & Johnson Medical, Inc. Cellulose oxidation by a perfluorinated hydrocarbon solution of nitrogen dioxide
US5414079A (en) * 1993-08-03 1995-05-09 Biocontrol Incorporated Oxidized cellulose

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EP0625992A1 (de) 1994-11-30
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