ES2103032T3 - Vector particular biodegradable y procedimiento de sintesis. - Google Patents

Vector particular biodegradable y procedimiento de sintesis.

Info

Publication number
ES2103032T3
ES2103032T3 ES92911799T ES92911799T ES2103032T3 ES 2103032 T3 ES2103032 T3 ES 2103032T3 ES 92911799 T ES92911799 T ES 92911799T ES 92911799 T ES92911799 T ES 92911799T ES 2103032 T3 ES2103032 T3 ES 2103032T3
Authority
ES
Spain
Prior art keywords
biodegradable
particular vector
synthesis procedure
vector
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92911799T
Other languages
English (en)
Inventor
Daniel Samain
Miguel Ignacio De
Jaouad Meniali
Karim Ioualalen
Li Ding
Monique Cervilla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biovector Therapeutics SA
Original Assignee
Biovector Therapeutics SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovector Therapeutics SA filed Critical Biovector Therapeutics SA
Application granted granted Critical
Publication of ES2103032T3 publication Critical patent/ES2103032T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Laminated Bodies (AREA)
  • Wrappers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN VECTOR PARTICULAR BIODEGRADABLE, CARACTERIZADO EN QUE COMPRENDE: UN NUCLEO QUE CONSTITUYE UNA MATRIZ POLISACARIDICA U OLIGOSACRARIDICA RETICULADA, SOBRE LA CUAL ESTAN INJERTADOS UNOS LIGANDOS IONICOS, UNA PRIMERA CAPA LIPIDICA SEMIPERMEABLE, UNIDA AL NUCLEO POR ENLACES COVALENTES, UNA SEGUNDA CAPA DE COMPUESTOS ANFIFILOS, UNIDOS A LA PRIMERA CAPA LIPIDICA POR INTERACCIONES HIDROFOBAS. SE REFIERE TAMBIEN A UN PROCESO QUE PERMITE LA SINTESIS DE TAL VECTOR.
ES92911799T 1991-06-04 1992-06-04 Vector particular biodegradable y procedimiento de sintesis. Expired - Lifetime ES2103032T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9106743A FR2677249B1 (fr) 1991-06-04 1991-06-04 Vecteur particulaire biodegradable et procede de synthese.

Publications (1)

Publication Number Publication Date
ES2103032T3 true ES2103032T3 (es) 1997-08-16

Family

ID=9413451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92911799T Expired - Lifetime ES2103032T3 (es) 1991-06-04 1992-06-04 Vector particular biodegradable y procedimiento de sintesis.

Country Status (11)

Country Link
EP (1) EP0542969B1 (es)
JP (1) JPH06500570A (es)
KR (1) KR100258521B1 (es)
AT (1) ATE152619T1 (es)
CA (1) CA2088759A1 (es)
DE (1) DE69219561T2 (es)
DK (1) DK0542969T3 (es)
ES (1) ES2103032T3 (es)
FR (1) FR2677249B1 (es)
GR (1) GR3024217T3 (es)
WO (1) WO1992021329A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654006A (en) * 1993-02-12 1997-08-05 Mayo Foundation For Medical Education And Research Condensed-phase microparticle composition and method
ATE162397T1 (de) * 1993-02-12 1998-02-15 Mayo Foundation Zusammensetzung aus mikropartikeln in verdichteter phase und verfahren
FR2702160B1 (fr) * 1993-03-02 1995-06-02 Biovecteurs As Vecteurs particulaires synthétiques et procédé de préparation.
FR2704145B1 (fr) * 1993-04-21 1995-07-21 Pasteur Institut Vecteur particulaire et composition pharmaceutique le contenant.
FR2754828B1 (fr) * 1996-10-23 1998-12-24 Univ Toulouse Structure membranaire artificielle, procede et polymere pour sa preparation, procede de preparation de ce polymere, particule et film comprenant cette structure
FR2757876B1 (fr) * 1996-12-27 1999-04-09 Biovector Therapeutics Sa Conjuges d'un vecteur particulaire et d'oligonucleotides, leur procede de preparation et les compositions pharmaceutiques les contenant
FR2765496B1 (fr) * 1997-07-03 1999-09-24 Rosanne Raynal Microbilles appelees capsules a coeur polymerique capables de transporter des molecules, des principes actifs et/ou des cellules.
BRPI0801929A2 (pt) * 2008-05-13 2010-01-12 Santana Cristiano Alberto Ribeiro processo e composição farmacêutica compreendendo enzimas proteolìticas vegetais em nanopartìculas supramoleculares, para tratamento da doença de peyronie, colagenoses e patologias fibróticas e uso
US8716219B2 (en) * 2009-07-07 2014-05-06 Sabanci University Crosslinked protein nanocrystals, crosslinked protein nanoaggregates and method of preparation thereof
PT2506859T (pt) 2009-12-04 2016-08-12 Magle Ab Microesferas de amido hidrolisado com ligandos endógenos carregados
CN103958452B (zh) * 2011-09-29 2016-01-20 陶氏环球技术有限责任公司 原位制备水解酰卤化合物的方法
CA2881605A1 (en) 2012-08-14 2014-02-20 Aaron FROESE Internal structured self assembling liposomes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2631826B1 (fr) * 1988-05-27 1992-06-19 Centre Nat Rech Scient Vecteur particulaire utile notamment pour le transport de molecules a activite biologique et procede pour sa preparation
FR2646777B1 (fr) * 1989-05-12 1993-09-03 Bio Serae Lab Procede de preparation d'un produit particulaire antimicrobien, produit antimicrobien obtenu et applications

Also Published As

Publication number Publication date
CA2088759A1 (fr) 1992-12-05
JPH06500570A (ja) 1994-01-20
WO1992021329A1 (fr) 1992-12-10
KR930701158A (ko) 1993-06-11
GR3024217T3 (en) 1997-10-31
EP0542969B1 (fr) 1997-05-07
DE69219561D1 (de) 1997-06-12
FR2677249B1 (fr) 1995-03-17
EP0542969A1 (fr) 1993-05-26
ATE152619T1 (de) 1997-05-15
KR100258521B1 (ko) 2000-08-01
FR2677249A1 (fr) 1992-12-11
DK0542969T3 (da) 1997-11-03
DE69219561T2 (de) 1997-11-13

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