ES2105567T3 - Ceramidas, su procedimiento de preparacion y sus aplicaciones en cosmetica. - Google Patents

Ceramidas, su procedimiento de preparacion y sus aplicaciones en cosmetica.

Info

Publication number
ES2105567T3
ES2105567T3 ES94402272T ES94402272T ES2105567T3 ES 2105567 T3 ES2105567 T3 ES 2105567T3 ES 94402272 T ES94402272 T ES 94402272T ES 94402272 T ES94402272 T ES 94402272T ES 2105567 T3 ES2105567 T3 ES 2105567T3
Authority
ES
Spain
Prior art keywords
ceramids
cosmetics
applications
preparation procedure
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94402272T
Other languages
English (en)
Inventor
Didier Semeria
Michel Philippe
Claude Mahieu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9451732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2105567(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of ES2105567T3 publication Critical patent/ES2105567T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/04Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06Lipsticks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • A61Q1/10Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00Manicure or pedicure preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

LAS CERAMIDAS SEGUN LA INVENCION SON COMPUESTOS QUE RESPONDEN A LA FORMULA: EN LA QUE: R1 ES UN RADICAL ALKILO O ALCENILO EN C11 A C21; R21 ES UN RADICAL HIDROXIALKILO LINEAL O RAMIFICADO EN C1 A C29 O UN RADICAL HIDROXIALKILO EN C7 A C29, ESTANDO ESTOS COMPUESTOS EN FORMA DE UNA MEZCLA RACEMICA DE LOS DIASTEREOISOMEROS ERITRO Y TREO, PARA LA PARTE AMINODIOL, EN LAS PROPORCIONES ERITRO : TREO DE 85 : 15 A 20 : 80. APLICACION EN LAS COMPOSICIONES COSMETICAS Y DERMOFARMACEUTICAS.
ES94402272T 1993-10-12 1994-10-11 Ceramidas, su procedimiento de preparacion y sus aplicaciones en cosmetica. Expired - Lifetime ES2105567T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9312106A FR2711138B1 (fr) 1993-10-12 1993-10-12 Céramides, leur procédé de préparation et leurs applications en cosmétique et en dermopharmacie.

Publications (1)

Publication Number Publication Date
ES2105567T3 true ES2105567T3 (es) 1997-10-16

Family

ID=9451732

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94402272T Expired - Lifetime ES2105567T3 (es) 1993-10-12 1994-10-11 Ceramidas, su procedimiento de preparacion y sus aplicaciones en cosmetica.

Country Status (16)

Country Link
US (2) US5665778A (es)
EP (1) EP0647617B1 (es)
JP (1) JP3687997B2 (es)
KR (1) KR100298306B1 (es)
CN (1) CN1043227C (es)
AT (1) ATE155773T1 (es)
BR (1) BR9404071A (es)
CA (1) CA2117939C (es)
DE (1) DE69404412T2 (es)
DK (1) DK0647617T3 (es)
ES (1) ES2105567T3 (es)
FR (1) FR2711138B1 (es)
GR (1) GR3024901T3 (es)
HU (1) HU222500B1 (es)
PL (1) PL177020B1 (es)
RU (1) RU2141944C1 (es)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2729296B1 (fr) * 1995-01-12 1997-03-28 Europlanaire Compositions pharmaceutiques comprenant une superoxyde dismutase
DE19533330A1 (de) * 1995-09-11 1997-03-13 Beiersdorf Ag Gegen Hautkrebs wirksame topische Zubereitungen
FR2740031B1 (fr) 1995-10-20 1997-11-28 Oreal Nouvelle composition reductrice et nouveau procede pour la deformation permanente des cheveux
FR2740035B1 (fr) * 1995-10-20 1997-11-28 Oreal Procede de teinture des fibres keratiniques et composition mise en oeuvre au cours de ce procede
FR2740036B1 (fr) * 1995-10-20 1997-11-28 Oreal Nouvelle composition oxydante et nouveau procede pour la deformation permanente ou la decoloration des cheveux
FR2740034B1 (fr) * 1995-10-23 1997-11-21 Oreal Composition pour le traitement des matieres keratiniques comprenant au moins un polymere fixant et au moins un compose de type ceramide et procedes
FR2747567B1 (fr) * 1996-04-22 1998-05-22 Oreal Utilisation de ceramide pour le traitement des ongles
FR2750046B1 (fr) * 1996-06-19 1998-09-04 Oreal Compositions sous forme d'un gel aqueux comprenant un ceramide ou un compose de type ceramide
DE19637966C1 (de) * 1996-09-18 1998-02-12 Wella Ag Mittel zum Färben von Haaren
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
KR19980034991A (ko) * 1996-11-11 1998-08-05 안용찬 비천연세라미드 관련화합물 및 이를 함유하는 피부외용제
AU6781198A (en) * 1997-05-09 1998-11-27 Avon Products Inc. Cosmetic sticks containing microcapsules
FR2770523B1 (fr) 1997-11-04 1999-12-31 Oreal Compose de type ceramide, procede de preparation et utilisation
US6379659B1 (en) 1997-11-18 2002-04-30 Takasago International Corporation Keratin fiber strengthening agent and method for strengthening keratin fiber
FR2775977B1 (fr) * 1998-03-10 2000-06-23 Oreal Composes lipidiques derives des bases sphingoides, leur procede de preparation et leurs utilisations en cosmetique et en dermopharmacie
FR2776510B1 (fr) 1998-03-31 2002-11-29 Oreal Derives de polyamino-acides et leur utilisation dans des compositions de traitement des fibres keratiniques
DE19847149A1 (de) * 1998-10-13 2000-04-20 Max Planck Gesellschaft Pseudo-Ceramide
FR2799650B1 (fr) 1999-10-14 2001-12-07 Oreal Procede pour limiter la penetration dans la peau et/ou les fibres keratiniques d'un agent cosmetique et/ou pharmaceutique actif
FR2799956B1 (fr) * 1999-10-20 2001-12-07 Oreal Compositions cosmetiques contenant un copolymere vintldimethicone/dimethicone en emulsion aqueuse et un epaississant associatif et leurs utilisations
RU2162318C1 (ru) * 2000-03-23 2001-01-27 Открытое акционерное общество "Косметическое объединение "Свобода" Крем косметический
AU2001255199A1 (en) * 2000-03-28 2001-10-08 The Liposome Company, Inc. Ceramide derivatives and method of use
JP4350269B2 (ja) 2000-05-11 2009-10-21 高砂香料工業株式会社 化粧料添加用組成物
FR2811556B1 (fr) * 2000-07-11 2002-09-06 Oreal Composition comprenant un precurseur de ceramides, utilisation pour ameliorer l'epiderme naturel ou reconstruit , equivalent de peau obtenu
DE10050782A1 (de) 2000-10-13 2002-04-25 Goldwell Gmbh Haarpflegemittel
US7128924B2 (en) * 2001-02-12 2006-10-31 Council Of Scientific & Industrial Research Safe, eco-friendly, health protective herbal colors and aroma useful for cosmaceutical applications
AU2002326461A1 (en) * 2001-07-30 2003-02-17 Pragmatic Vision International, Llc A dissolving agent for melanin and methods of applying such an agent to keratinous fibers
US20030047292A1 (en) 2001-09-13 2003-03-13 Skyline Displays, Inc. Modular multi-configurable display system
JP2003327519A (ja) * 2002-05-10 2003-11-19 Kao Corp 染毛剤組成物
EP1534218B1 (fr) * 2002-09-06 2009-12-16 L'oreal Composition de maquillage des fibres keratiniques notamment des fibres keratiniques comme les cils
DE10255554A1 (de) * 2002-11-28 2004-06-17 Goldschmidt Ag Emulgator-Wachs-Gele auf Wasserbasis
CN100438852C (zh) * 2002-12-25 2008-12-03 花王株式会社 毛发清洁剂
FR2858550B1 (fr) * 2003-08-06 2007-05-18 Oreal Composition de maquillage de matieres keratiniques notamment de fibres keratiniques, comme les cils.
US20050069508A1 (en) * 2003-08-06 2005-03-31 Karl Pays Cosmetic composition comprising a dispersion of at least one wax in at least one volatile oil
US8211449B2 (en) * 2004-06-24 2012-07-03 Dpt Laboratories, Ltd. Pharmaceutically elegant, topical anhydrous aerosol foam
FR2874610A1 (fr) * 2004-09-02 2006-03-03 Oreal Nouveaux ceramides, leur preparation, leur utilisation pour former des dispersions de spherules, compositions les comprenant, et procede de traitement
FR2877842B1 (fr) * 2004-11-13 2008-12-12 Unilever Nv Naamlooze Vennoots Produit aerosol anti-transpirant
DE102005057593A1 (de) * 2005-07-08 2007-01-11 Schwan-Stabilo Cosmetics Gmbh & Co. Kg Zubereitung, insbesondere kosmetische Zubereitung, sowie ihre Herstellung und Verwendung
FR2894961B1 (fr) * 2005-12-16 2008-05-16 Oreal Utilisation de ceramides pour depigmenter la peau
KR20090103869A (ko) 2006-11-02 2009-10-01 메루샹가부시키가이샤 세라미드 합성 촉진제, 화장료, 피부 외용제, 노화 방지 방법 및 주름 개선방법
FR2911271B1 (fr) * 2007-01-12 2012-12-07 Oreal Utilisation de precurseurs de ceramide a titre d'agent protecteur des levres fragiles
EP1955692A1 (fr) * 2007-01-12 2008-08-13 L'oreal Utilisation d'actifs permettant d'augmenter la teneur en céramides dans les lèvres, à titre d'agent protecteur des lèvres fragiles
EP2111842A1 (fr) 2008-03-28 2009-10-28 L'Oréal Composition tinctoriale comprenant du chlorure d'ammonium, procédé de coloration de fibres kératiniques et dispositif
CA2803523A1 (en) 2010-06-30 2012-01-05 Galderma S.A. Moisturizing composition with spf 30
FR2973237A1 (fr) 2011-03-31 2012-10-05 Oreal Procede de traitement cosmetique fractionne utilisant un laser ou des micro-aiguilles
FR2987742B1 (fr) 2012-03-09 2014-09-26 Oreal Procede de traitement pour la protection et la reparation des fibres keratiniques mettant en œuvre des polysaccharides oxydes
FR2988602B1 (fr) 2012-03-27 2014-09-05 Oreal Procede cosmetique de soin et/ou de maquillage des matieres keratiniques
US9861702B2 (en) 2012-10-22 2018-01-09 Wisconsin Alumni Research Foundation Lipid-conjugated rhamnose for immune system recruitment and oncotherapy
EP2727929A1 (en) * 2012-10-30 2014-05-07 Wittycell Method of preparation of alpha galactosyl ceramides compounds
FR3001144B1 (fr) 2013-01-18 2015-07-17 Oreal Composition cosmetique solide souple comprenant des tensioactifs anioniques et des agents conditionneurs polymeriques, et procede de traitement cosmetique
FR3001147B1 (fr) 2013-01-18 2015-07-17 Oreal Composition cosmetique solide souple, comprenant des tensioactifs anio-niques et des particules solides, et procede de traitement cosmetique
FR3001145B1 (fr) 2013-01-18 2015-07-17 Oreal Composition cosmetique solide souple comprenant des tensioactifs anio-niques et des polyols, et procede de traitement cosmetique
FR3010308B1 (fr) 2013-09-12 2016-11-25 Oreal Procede de traitement des fibres keratiniques avec un compose d'acide pyridine dicarboxylique
FR3010309B1 (fr) 2013-09-12 2017-03-10 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose de sphingosine
FR3010312B1 (fr) 2013-09-12 2015-09-11 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose d'acide pyridine dicarboxylique
DE102013225843A1 (de) * 2013-12-13 2015-06-18 Henkel Ag & Co. Kgaa Kosmetische Zusammensetzung enthaltend eine Kombination aus Carbonsäure-N-alkylpolyhydroxyalkylamiden und Ceramiden
JP6510177B2 (ja) 2014-04-01 2019-05-08 ロレアル ナノ又はマイクロエマルションの形態の組成物
JP6537788B2 (ja) 2014-06-25 2019-07-03 ロレアル ナノエマルション若しくはマイクロエマルションの形態の又はラメラ構造を有する組成物
CN105732412B (zh) * 2016-03-10 2017-07-28 陕西中医药大学 一种用于治疗中风的酰胺类化合物及其制备方法
KR102703167B1 (ko) * 2016-09-27 2024-09-06 (주)아모레퍼시픽 유사 세라마이드 화합물 및 그 제조방법
KR102496498B1 (ko) * 2016-10-14 2023-02-07 주식회사 다이셀 화장료 조성물
JP2018087149A (ja) 2016-11-28 2018-06-07 ロレアル ナノ又はマイクロエマルションの形態の組成物
JP2019196311A (ja) 2018-04-16 2019-11-14 ロレアル O/w型の形態の組成物
CN112759535B (zh) * 2019-11-01 2024-04-05 广东东阳光药业股份有限公司 一种pf-06651600中间体的制备方法
WO2023184210A1 (en) 2022-03-30 2023-10-05 L'oreal Composition for caring for keratin materials
CN120693143A (zh) 2023-03-29 2025-09-23 莱雅公司 用于清洁皮肤的组合物
FR3148912B1 (fr) 2023-05-24 2026-02-20 Oreal Composition comprenant des polymères cationiques et anioniques
EP4734935A1 (en) 2023-06-30 2026-05-06 L'oreal Composition for conditioning the hair

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EP0633875B1 (en) * 1992-04-03 1997-01-02 Gist-Brocades N.V. Selective n-acylation of amino alcohols

Also Published As

Publication number Publication date
BR9404071A (pt) 1995-06-13
DE69404412T2 (de) 1997-12-04
FR2711138A1 (fr) 1995-04-21
HU9402945D0 (en) 1995-02-28
US5665778A (en) 1997-09-09
PL177020B1 (pl) 1999-09-30
PL305416A1 (en) 1995-04-18
CN1112108A (zh) 1995-11-22
EP0647617A1 (fr) 1995-04-12
FR2711138B1 (fr) 1995-11-24
DK0647617T3 (da) 1998-03-02
JP3687997B2 (ja) 2005-08-24
DE69404412D1 (de) 1997-09-04
HU222500B1 (hu) 2003-07-28
CA2117939C (fr) 2006-05-02
CA2117939A1 (fr) 1995-04-13
CN1043227C (zh) 1999-05-05
HUT71595A (en) 1996-01-29
GR3024901T3 (en) 1998-01-30
EP0647617B1 (fr) 1997-07-23
RU94036748A (ru) 1996-08-10
JPH07165690A (ja) 1995-06-27
US5959127A (en) 1999-09-28
KR100298306B1 (ko) 2001-10-22
RU2141944C1 (ru) 1999-11-27
KR950011400A (ko) 1995-05-15
ATE155773T1 (de) 1997-08-15

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