ES2105798T3 - Amidas de acido sulfonamidocarbonilpiridin-2-carboxilico asi como sus piridin-n-oxidos, procedimiento para su preparacion y su empleo como medicamento. - Google Patents

Amidas de acido sulfonamidocarbonilpiridin-2-carboxilico asi como sus piridin-n-oxidos, procedimiento para su preparacion y su empleo como medicamento.

Info

Publication number
ES2105798T3
ES2105798T3 ES95103581T ES95103581T ES2105798T3 ES 2105798 T3 ES2105798 T3 ES 2105798T3 ES 95103581 T ES95103581 T ES 95103581T ES 95103581 T ES95103581 T ES 95103581T ES 2105798 T3 ES2105798 T3 ES 2105798T3
Authority
ES
Spain
Prior art keywords
sulfonamidocarbonylpiridin
piridin
oxides
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95103581T
Other languages
English (en)
Inventor
Klaus Dr Weidmann
Martin Dr Bickel
Volkmar Dr Gunzler-Pukall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2105798T3 publication Critical patent/ES2105798T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A SULFONAMIDO CARBONILPIRIDINA 2 AMIDA ACIDO CARBOXILICO Y SU OXIDO N - PIRIDINA, SEGUN LA FORMULA GENERAL I LOS COMPUESTOS CONOCIDOS ENCUENTRAN UTILIZACION COMO MEDICAMENTO CONTRA ENFERMEDADES FIBROTICAS, COMO ELEMENTOS FIBROSUPRESIVOS Y COMO INHIBIDORES DE PROLILHIDROXILASA Y DE LA BIOSINTESIS DE COLAGENO.
ES95103581T 1994-03-25 1995-03-13 Amidas de acido sulfonamidocarbonilpiridin-2-carboxilico asi como sus piridin-n-oxidos, procedimiento para su preparacion y su empleo como medicamento. Expired - Lifetime ES2105798T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410423A DE4410423A1 (de) 1994-03-25 1994-03-25 Sulfonamidocarbonylpyridin-2-carbonsäureamide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ES2105798T3 true ES2105798T3 (es) 1997-10-16

Family

ID=6513863

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95103581T Expired - Lifetime ES2105798T3 (es) 1994-03-25 1995-03-13 Amidas de acido sulfonamidocarbonilpiridin-2-carboxilico asi como sus piridin-n-oxidos, procedimiento para su preparacion y su empleo como medicamento.

Country Status (19)

Country Link
US (1) US5610172A (es)
EP (1) EP0673931B1 (es)
JP (1) JPH07278109A (es)
KR (1) KR950032124A (es)
CN (1) CN1114312A (es)
AT (1) ATE156815T1 (es)
AU (1) AU689199B2 (es)
CA (1) CA2145476A1 (es)
CZ (1) CZ287768B6 (es)
DE (2) DE4410423A1 (es)
DK (1) DK0673931T3 (es)
ES (1) ES2105798T3 (es)
FI (1) FI951386L (es)
GR (1) GR3024860T3 (es)
HU (1) HUT72059A (es)
NO (1) NO304308B1 (es)
NZ (1) NZ270783A (es)
PL (1) PL180042B1 (es)
ZA (1) ZA952408B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191368B1 (en) 1995-09-12 2001-02-20 Tessera, Inc. Flexible, releasable strip leads
CN102552263A (zh) 2001-12-06 2012-07-11 法布罗根股份有限公司 提高内源性红细胞生成素(epo)的方法
EP2295060B1 (en) 2001-12-06 2018-10-31 Fibrogen, Inc. Treatment or prevention of ischemic or hypoxic conditions
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US7618940B2 (en) 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US8614204B2 (en) * 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US7764995B2 (en) * 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) * 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US7828711B2 (en) * 2004-08-16 2010-11-09 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular growth and regeneration using ventricular assist device
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
AU2006259352A1 (en) 2005-06-15 2006-12-28 Fibrogen, Inc. Use of HIF 1alfa modulators for treatment of cancer
US7774057B2 (en) 2005-09-06 2010-08-10 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression for cardiac protection
WO2007114612A1 (en) * 2006-03-30 2007-10-11 Lg Electronics Inc. A method and apparatus for decoding/encoding a video signal
BRPI0713350B1 (pt) 2006-06-26 2022-04-12 Akebia Therapeutics Inc Composto, e, composição
US8962530B2 (en) * 2007-06-27 2015-02-24 Regents Of The University Of Colorado Inflammatory bowel disease therapies
NO2686520T3 (es) 2011-06-06 2018-03-17
SG10201910773VA (en) 2013-06-13 2020-01-30 Akebia Therapeutics Inc Compositions and methods for treating anemia
AR099354A1 (es) 2013-11-15 2016-07-20 Akebia Therapeutics Inc Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acético, composiciones, y sus usos
AU2016209126A1 (en) 2015-01-23 2017-08-10 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
US11324734B2 (en) 2015-04-01 2022-05-10 Akebia Therapeutics, Inc. Compositions and methods for treating anemia
EP3790863A1 (en) 2018-05-09 2021-03-17 Akebia Therapeutics Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
CZ287768B6 (en) 2001-01-17
US5610172A (en) 1997-03-11
DE59500488D1 (de) 1997-09-18
EP0673931A1 (de) 1995-09-27
CN1114312A (zh) 1996-01-03
ZA952408B (en) 1995-11-27
EP0673931B1 (de) 1997-08-13
DK0673931T3 (da) 1998-03-16
NZ270783A (en) 1997-02-24
GR3024860T3 (en) 1998-01-30
NO304308B1 (no) 1998-11-30
AU689199B2 (en) 1998-03-26
NO951146D0 (no) 1995-03-24
FI951386A7 (fi) 1995-09-26
PL307848A1 (en) 1995-10-02
DE4410423A1 (de) 1995-09-28
JPH07278109A (ja) 1995-10-24
HU9500865D0 (en) 1995-05-29
CZ73395A3 (en) 1995-11-15
NO951146L (no) 1995-09-26
HK1012338A1 (en) 1999-07-30
ATE156815T1 (de) 1997-08-15
FI951386A0 (fi) 1995-03-23
HUT72059A (en) 1996-03-28
PL180042B1 (en) 2000-12-29
CA2145476A1 (en) 1995-09-26
KR950032124A (ko) 1995-12-20
FI951386L (fi) 1995-09-26
AU1504295A (en) 1995-10-05

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