ES2106326T3 - Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica. - Google Patents
Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica.Info
- Publication number
- ES2106326T3 ES2106326T3 ES93905315T ES93905315T ES2106326T3 ES 2106326 T3 ES2106326 T3 ES 2106326T3 ES 93905315 T ES93905315 T ES 93905315T ES 93905315 T ES93905315 T ES 93905315T ES 2106326 T3 ES2106326 T3 ES 2106326T3
- Authority
- ES
- Spain
- Prior art keywords
- immunological
- substrate
- analytics
- procedure
- measurement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6091—Cartridges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
- G01N30/6039—Construction of the column joining multiple columns in series
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN RECIPIENTE DE REACCION DE UNA VIA, ABIERTO EN AMBOS EXTREMOS, PARA ANALISIS INMUNOLOGICO DE FASE SOLIDA, CON AL MENOS UN COMPONENTE REACTIVO INMUNOLOGICAMENTE APLICADO SOBRE UN SUBSTRATO CON UNA SUPERFICIE ACTIVA O ACTIVADA. EL COMPONENTE REACTIVO INDICADO DISPONE DE UNA DENSIDAD DE CARGA TAL, QUE EL CONSTITUYENTE A SER DETERMINADO ENLAZA CUANTITATIVAMENTE (ENLACE DE EQUILIBRIO) AL CONSTITUYENTE REACTIVO ANTES DE QUE EL LIQUIDO QUE FLUYE DEJE EL SUBSTRATO; SIENDO EL VOLUMEN DEL LECHO DE SUBSTRATO HASTA 600 MICROLITROS, Y LA VELOCIDAD DEL FLUJO DEL LIQUIDO A PARTIR DEL LECHO DE SUBSTRATO SE DETERMINA DE FORMA CORRESPONDIENTE. EL RECIPIENTE DE REACCION DE UNA VIA PUEDE SER UTILIZADO PARA MEDIR CONSTITUYENTES QUE PUEDEN SER DETERMINADOS SOBRE LA BASE DE REACCIONES INMUNES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4208732A DE4208732C2 (de) | 1992-03-18 | 1992-03-18 | Einwegreaktionsgefäß für die Festphasenimmunanalytik und Verfahren zur Messung von über Immunreaktionen bestimmbaren Komponenten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2106326T3 true ES2106326T3 (es) | 1997-11-01 |
Family
ID=6454401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93905315T Expired - Lifetime ES2106326T3 (es) | 1992-03-18 | 1993-03-08 | Reactor desechable para la analitica inmunologica en fase solida y procedimiento para la medicion de componentes determinables mediante una reaccion inmunologica. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0634015B1 (es) |
| JP (1) | JPH07504983A (es) |
| KR (1) | KR100270209B1 (es) |
| AT (1) | ATE158081T1 (es) |
| AU (1) | AU675781B2 (es) |
| BR (1) | BR9306086A (es) |
| CA (1) | CA2131007A1 (es) |
| CZ (1) | CZ217294A3 (es) |
| DE (2) | DE4208732C2 (es) |
| ES (1) | ES2106326T3 (es) |
| FI (1) | FI944320L (es) |
| HU (1) | HUT74558A (es) |
| NO (1) | NO943462D0 (es) |
| NZ (1) | NZ249491A (es) |
| RU (1) | RU2115122C1 (es) |
| SK (1) | SK109894A3 (es) |
| WO (1) | WO1993019368A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09507577A (ja) * | 1994-01-13 | 1997-07-29 | アビオン ベタイリゲンズ− ウント ベルワルトゥングスゲゼルシャフト ミット ベシュレンクテル ハフツング | 多対象同時測定用反応カラムと方法 |
| DE19528847C2 (de) * | 1995-08-05 | 1997-12-11 | Biotest Ag | Affinitätschromatographisches Verfahren zum Nachweis von Antigenen und/oder Antikörpern |
| DE19543240A1 (de) * | 1995-11-20 | 1997-05-22 | Abion Ohg | Einwegauftragsvorrichtung sowie Kit |
| EP0879416A1 (de) * | 1996-01-30 | 1998-11-25 | Abion Beteiligungs- Und Verwaltungsgesellschaft Mbh | Im durchfluss beladbares trägermaterial für festphasenassays |
| GB9708961D0 (en) * | 1997-05-02 | 1997-06-25 | Ringel Karl Peter | Immunoassay |
| WO1999024138A1 (en) * | 1997-11-12 | 1999-05-20 | Life Technologies, Inc. | Device and methods for purifying biological molecules using low volumes of chromatographic and adsorptive media |
| DE29803712U1 (de) * | 1998-03-04 | 1998-04-23 | Macherey, Nagel GmbH & Co. Handelsgesellschaft, 52355 Düren | Vorrichtung zur Behandlung von Biomolekülen |
| US6177009B1 (en) | 1998-04-03 | 2001-01-23 | Macherey, Nagel Gmbh & Co. | Apparatus for treating biomolecules |
| DE10057195A1 (de) * | 2000-11-17 | 2002-05-23 | Robert Loesel | Reaktionsgefäß mit Membranboden |
| DE10247430A1 (de) * | 2002-10-11 | 2004-04-29 | Fresenius Hemocare Gmbh | Verfahren zur Bestimmung des Gehalts an Endotoxinen in Flüssigkeiten |
| DE20218503U1 (de) | 2002-11-28 | 2003-03-06 | Macherey, Nagel GmbH & Co. Handelsgesellschaft, 52355 Düren | Trennvorrichtung zur Behandlung von Biomolekülen |
| DE102007025311A1 (de) | 2007-05-30 | 2008-12-04 | Senova Gesellschaft für Biowissenschaft und Technik mbH | Quantitativer heterogener schneller Bindungsassay mit breitem dynamischen Bereich und einfacher photometrischer Detektion |
| RU2395093C9 (ru) * | 2007-10-31 | 2010-11-20 | Учреждение Российской академии наук Институт общей физики им. А.М. Прохорова РАН (ИОФ РАН) | Устройство для твердофазного иммуноанализа и способ твердофазного иммуноанализа |
| GB0802355D0 (en) * | 2008-02-08 | 2008-03-12 | Univ Greenwich | Modified SPE adsorbent cartridge |
| EP2264461A1 (de) | 2009-06-19 | 2010-12-22 | FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie | Vorrichtung zur Durchführung eines affinitätschromatographischen Probentests |
| WO2012016720A1 (en) * | 2010-08-05 | 2012-02-09 | Vibod Gmbh | New columns for incubation and isolation of chemical and/or biological samples |
| EP2487490A1 (de) | 2011-02-11 | 2012-08-15 | FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie | Heterogener Bindungsassay mit verbesserter optischer Auswertbarkeit oder poröse Festphase für Bindungsassays mit verbesserter optischer Auswertbarkeit |
| EP2775987A4 (en) * | 2011-11-10 | 2015-11-25 | Biofire Diagnostics Llc | LOADING PHYOLS |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1907014A1 (de) * | 1969-02-12 | 1970-09-03 | Haller Dr Wolfgang | Verfahren zur Trennung von Blutkomponenten,insbesondere von immunologisch aktiven Globulinen,von anderen Komponenten |
| US4039652A (en) * | 1973-10-11 | 1977-08-02 | Miles Laboratories, Inc. | Column method of immunoassay employing an immobilized binding partner |
| US4151254A (en) * | 1975-06-16 | 1979-04-24 | Union Carbide Corporation | Adsorption columns for use in radioimmunoassays |
| US4145406A (en) * | 1977-04-11 | 1979-03-20 | Miles Laboratories, Inc. | Specific binding - adsorbent assay method and test means |
| SE458643B (sv) * | 1984-12-07 | 1989-04-17 | Pharmacia Ab | Anordning med kolonnelement uppdelat i provparti och referenspatri |
| JPH087217B2 (ja) * | 1986-04-09 | 1996-01-29 | オリンパス光学工業株式会社 | アフイニテイ−クロマトグラフイ−を応用した免疫学的測定方法 |
| JPH07119769B2 (ja) * | 1986-10-01 | 1995-12-20 | 株式会社日立製作所 | 自動分析装置 |
| DE3717211A1 (de) * | 1987-05-22 | 1988-12-01 | Diagen Inst Molekularbio | Vorrichtung und verfahren zur trennung und reinigung von molekuelen |
| US4892710A (en) * | 1987-07-07 | 1990-01-09 | Bioprobe International, Inc. | Cartridge assembly with multi-purpose closure tubing |
| DD268161A1 (de) * | 1987-11-27 | 1989-05-24 | Staatliches Inst Fuer Immunpra | Verfahren zur herstellung von bakteriellen antigenen |
| GB8928501D0 (en) * | 1989-12-18 | 1990-02-21 | Unilever Plc | Reagents |
| US5183740A (en) * | 1990-02-23 | 1993-02-02 | The United States Of America As Represented By The Secretary Of The Navy | Flow immunosensor method and apparatus |
| DE4126436A1 (de) * | 1990-09-17 | 1992-03-19 | Abion Ohg | Einwegreaktionsgefaess fuer die festphasenimmunanalytik und verfahren zur messung von ueber immunreaktionen bestimmbaren komponenten |
-
1992
- 1992-03-18 DE DE4208732A patent/DE4208732C2/de not_active Expired - Fee Related
-
1993
- 1993-03-08 KR KR1019940703222A patent/KR100270209B1/ko not_active Expired - Fee Related
- 1993-03-08 WO PCT/EP1993/000520 patent/WO1993019368A1/de not_active Ceased
- 1993-03-08 AT AT93905315T patent/ATE158081T1/de active
- 1993-03-08 RU RU94041215A patent/RU2115122C1/ru active
- 1993-03-08 CA CA002131007A patent/CA2131007A1/en not_active Abandoned
- 1993-03-08 DE DE59307345T patent/DE59307345D1/de not_active Expired - Lifetime
- 1993-03-08 JP JP5516208A patent/JPH07504983A/ja active Pending
- 1993-03-08 SK SK1098-94A patent/SK109894A3/sk unknown
- 1993-03-08 EP EP93905315A patent/EP0634015B1/de not_active Expired - Lifetime
- 1993-03-08 CZ CZ942172A patent/CZ217294A3/cs unknown
- 1993-03-08 AU AU36316/93A patent/AU675781B2/en not_active Ceased
- 1993-03-08 ES ES93905315T patent/ES2106326T3/es not_active Expired - Lifetime
- 1993-03-08 HU HU9402654A patent/HUT74558A/hu unknown
- 1993-03-08 NZ NZ249491A patent/NZ249491A/en unknown
- 1993-03-08 BR BR9306086A patent/BR9306086A/pt not_active Application Discontinuation
- 1993-03-08 FI FI944320A patent/FI944320L/fi not_active Application Discontinuation
-
1994
- 1994-09-16 NO NO943462A patent/NO943462D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE4208732C2 (de) | 1995-04-27 |
| FI944320A7 (fi) | 1994-09-16 |
| ATE158081T1 (de) | 1997-09-15 |
| AU675781B2 (en) | 1997-02-20 |
| WO1993019368A1 (de) | 1993-09-30 |
| CA2131007A1 (en) | 1993-09-30 |
| NO943462L (no) | 1994-09-16 |
| NZ249491A (en) | 1996-06-25 |
| KR100270209B1 (ko) | 2001-01-15 |
| BR9306086A (pt) | 1997-11-18 |
| SK109894A3 (en) | 1995-05-10 |
| RU2115122C1 (ru) | 1998-07-10 |
| DE4208732A1 (de) | 1993-09-30 |
| FI944320A0 (fi) | 1994-09-16 |
| AU3631693A (en) | 1993-10-21 |
| KR950701076A (ko) | 1995-02-20 |
| CZ217294A3 (en) | 1995-02-15 |
| EP0634015A1 (de) | 1995-01-18 |
| EP0634015B1 (de) | 1997-09-10 |
| HU9402654D0 (en) | 1994-11-28 |
| NO943462D0 (no) | 1994-09-16 |
| HUT74558A (en) | 1997-01-28 |
| FI944320L (fi) | 1994-09-16 |
| RU94041215A (ru) | 1996-10-10 |
| JPH07504983A (ja) | 1995-06-01 |
| DE59307345D1 (de) | 1997-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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