ES2106794T3 - Utilizacion del inositol-trifosfato para el tratamiento de inflamaciones. - Google Patents
Utilizacion del inositol-trifosfato para el tratamiento de inflamaciones.Info
- Publication number
- ES2106794T3 ES2106794T3 ES92107778T ES92107778T ES2106794T3 ES 2106794 T3 ES2106794 T3 ES 2106794T3 ES 92107778 T ES92107778 T ES 92107778T ES 92107778 T ES92107778 T ES 92107778T ES 2106794 T3 ES2106794 T3 ES 2106794T3
- Authority
- ES
- Spain
- Prior art keywords
- inositol
- triphosphate
- inflammations
- treatment
- isomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- MMWCIQZXVOZEGG-HOZKJCLWSA-N [(1S,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-4,6-diphosphonooxycyclohexyl] dihydrogen phosphate Chemical compound O[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(O)=O MMWCIQZXVOZEGG-HOZKJCLWSA-N 0.000 title abstract 3
- 206010061218 Inflammation Diseases 0.000 title 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910052804 chromium Inorganic materials 0.000 abstract 1
- 239000011651 chromium Substances 0.000 abstract 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract 1
- 229910052753 mercury Inorganic materials 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
USO DEL TRIFOSFATO DE INOSITOL PARA EL TRATAMIENTO DE LAS ENFERMEDADES ASOCIADAS CON INTOXICACIONES POR METALES. SE PRESENTA UN COMPUESTO FARMACEUTICO QUE CONTIENE COMO INGREDIENTE FARMACOLOGICAMENTE ACTIVO AL MENOS UN ISOMERO DEL TRIFOSFATO DE INOSITOL (IP3) EN UNA CANTIDAD SUFICIENTE PARA REDUCIR EL EFECTO NEGATIVO DEL PLOMO, MERCURIO, NIQUEL O CROMO EN EL CUERPO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8601709A SE465305B (sv) | 1986-04-16 | 1986-04-16 | Anvaendning av inositolfosfat foer framstaellning av ett laekemedel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2106794T3 true ES2106794T3 (es) | 1997-11-16 |
Family
ID=20364198
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92107778T Expired - Lifetime ES2106794T3 (es) | 1986-04-16 | 1987-04-15 | Utilizacion del inositol-trifosfato para el tratamiento de inflamaciones. |
| ES87105574T Expired - Lifetime ES2054628T3 (es) | 1986-04-16 | 1987-04-15 | Utilizacion del trifosfato de inositol para el tratamiento de la intoxicacion por metales. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87105574T Expired - Lifetime ES2054628T3 (es) | 1986-04-16 | 1987-04-15 | Utilizacion del trifosfato de inositol para el tratamiento de la intoxicacion por metales. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5019566A (es) |
| EP (2) | EP0508488B1 (es) |
| JP (1) | JP2528115B2 (es) |
| AT (1) | ATE157251T1 (es) |
| DE (2) | DE3752112T2 (es) |
| ES (2) | ES2106794T3 (es) |
| SE (1) | SE465305B (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128332A (en) * | 1984-10-23 | 1992-07-07 | Perstorp Ab | Method of treating cardiovascular diseases using inositoltrisphosphate |
| JPH01287035A (ja) * | 1988-05-13 | 1989-11-17 | Sanwa Kagaku Kenkyusho Co Ltd | 薬物並びにアルコール性中毒の予防剤とその治療剤 |
| JPH01294730A (ja) * | 1988-05-23 | 1989-11-28 | Mitsubishi Kasei Vinyl Co | ポリエステル系可塑剤 |
| SE464059C (sv) * | 1988-09-15 | 1997-06-02 | Perstorp Ab | Användning av inositoltrifosfat för framställning av läkemedel |
| US5427956A (en) * | 1989-03-08 | 1995-06-27 | The University Of Virginia Patent Foundation | Quantitative analysis for diabetic condition predictor |
| US5428066A (en) * | 1989-03-08 | 1995-06-27 | Larner; Joseph | Method of reducing elevated blood sugar in humans |
| US5750348A (en) * | 1989-03-08 | 1998-05-12 | The University Of Virginia Patents Foundation | Method for detecting insulin resistance |
| CA2019878A1 (en) * | 1989-09-13 | 1991-03-13 | Robert Sabin | Method of treatment of rheumatoid arthritis using phytic acid |
| JPH03115290A (ja) * | 1989-09-28 | 1991-05-16 | Yokohama Rubber Co Ltd:The | 1d―ミオイノシトール―1―リン酸の合成法 |
| SE8904355D0 (sv) * | 1989-12-21 | 1989-12-21 | Perstorp Ab | Medicament |
| SE9002278L (sv) * | 1990-06-28 | 1991-12-29 | Perstorp Ab | Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel |
| WO1995005830A1 (en) * | 1993-08-20 | 1995-03-02 | The Regents Of The University Of California | Polyanion anti-inflammatory agents |
| SE502989C2 (sv) * | 1993-11-22 | 1996-03-04 | Perstorp Ab | Användning av en inositoltrisfosfatester för beredning av läkemedel |
| US5536499A (en) * | 1995-02-24 | 1996-07-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cosmetic compositions for reducing or preventing signs of cellulite |
| US5523090A (en) * | 1995-02-24 | 1996-06-04 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Skin treatment composition |
| EP0728468A3 (en) | 1995-02-26 | 2000-07-19 | Unilever Plc | Cosmetic compositions for treating itchy skin |
| US5552148A (en) * | 1995-06-07 | 1996-09-03 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Petroleum jelly with inositol phosphates |
| US5614511A (en) * | 1996-03-11 | 1997-03-25 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cosmetic compositions for treating itchy skin |
| SE9602463D0 (sv) * | 1996-06-24 | 1996-06-24 | Perstorp Ab | The use of growth factor modulating compounds |
| US6949517B1 (en) * | 1996-06-24 | 2005-09-27 | Matti Siren | Method of treating inflammatory, tissue repair and infectious conditions |
| US5998485A (en) * | 1997-06-16 | 1999-12-07 | Cedars-Sinai Medical Center | Method for modulating immune response with inositol |
| US6221856B1 (en) | 1999-02-03 | 2001-04-24 | Inologic, Inc. | Inositol derivatives for inhibiting superoxide anion production |
| FR2828206B1 (fr) * | 2001-08-03 | 2004-09-24 | Centre Nat Rech Scient | Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire |
| WO2003092700A1 (en) | 2002-04-29 | 2003-11-13 | Gmp Oxycell, Inc. | Inositol pyrophosphates, and methods of use thereof |
| FI20021570A0 (fi) * | 2002-09-03 | 2002-09-03 | Gallen Kallela Siren Janne | Päällystetyn kirurgisen stentin paranneltu rakenne |
| US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| US7745423B2 (en) | 2004-07-06 | 2010-06-29 | NormOxys, Inc | Calcium/sodium salt of inositol tripyrophosphate as an allosteric effector of hemoglobin |
| US20060106000A1 (en) * | 2004-07-06 | 2006-05-18 | Claude Nicolau | Use of inositol-tripyrophosphate in treating tumors and diseases |
| US20060258626A1 (en) * | 2004-07-06 | 2006-11-16 | Claude Nicolau | Use of inositol-tripyrophosphate in treating tumors and diseases |
| WO2006102060A1 (en) * | 2005-03-18 | 2006-09-28 | Oxyplus, Inc. | Calcium salt of myo-inositol 1,6:2,3:4,5 tripyrophosphate as an allosteric effector of hemoglobin |
| US20090214474A1 (en) * | 2006-11-01 | 2009-08-27 | Barbara Brooke Jennings | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
| US20080103116A1 (en) * | 2006-11-01 | 2008-05-01 | Jennings-Spring Barbara L | Method of treatment and compositions of D-chiro inositol and phosphates thereof |
| US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
| CA2688233A1 (en) * | 2007-05-01 | 2008-11-06 | Normoxys, Inc. | Erythropoietin complementation or replacement |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2723938A (en) * | 1952-12-05 | 1955-11-15 | Bristol Lab Inc | Aqueous penicillin suspensions comprising inositol phosphoric acids and their salts |
| US3591665A (en) * | 1967-09-08 | 1971-07-06 | Mitsui Toatsu Chemicals | Process for producing phytic acid |
| SE465951B (sv) * | 1984-10-23 | 1991-11-25 | Perstorp Ab | Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav |
| JPH0338824A (ja) * | 1989-07-06 | 1991-02-19 | Nec Corp | 半導体細線の製造方法 |
| JPH0354924A (ja) * | 1989-07-24 | 1991-03-08 | Alpine Electron Inc | ダイバーシティラジオ受信機 |
| JP3136659B2 (ja) * | 1991-07-17 | 2001-02-19 | 松下電器産業株式会社 | 空気清浄器 |
-
1986
- 1986-04-16 SE SE8601709A patent/SE465305B/sv not_active IP Right Cessation
-
1987
- 1987-04-15 DE DE3752112T patent/DE3752112T2/de not_active Expired - Fee Related
- 1987-04-15 AT AT92107778T patent/ATE157251T1/de not_active IP Right Cessation
- 1987-04-15 ES ES92107778T patent/ES2106794T3/es not_active Expired - Lifetime
- 1987-04-15 DE DE3789576T patent/DE3789576T2/de not_active Expired - Fee Related
- 1987-04-15 EP EP92107778A patent/EP0508488B1/en not_active Expired - Lifetime
- 1987-04-15 ES ES87105574T patent/ES2054628T3/es not_active Expired - Lifetime
- 1987-04-15 EP EP87105574A patent/EP0252227B1/en not_active Expired - Lifetime
- 1987-04-16 JP JP62092107A patent/JP2528115B2/ja not_active Expired - Lifetime
-
1988
- 1988-03-28 US US07/173,985 patent/US5019566A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0252227B1 (en) | 1994-04-13 |
| EP0508488A3 (en) | 1992-10-28 |
| DE3752112D1 (de) | 1997-10-02 |
| EP0508488B1 (en) | 1997-08-27 |
| ES2054628T3 (es) | 1994-08-16 |
| DE3789576T2 (de) | 1994-08-25 |
| SE8601709D0 (sv) | 1986-04-16 |
| US5019566A (en) | 1991-05-28 |
| ATE157251T1 (de) | 1997-09-15 |
| DE3789576D1 (de) | 1994-05-19 |
| EP0508488A2 (en) | 1992-10-14 |
| SE8601709L (sv) | 1987-10-17 |
| JP2528115B2 (ja) | 1996-08-28 |
| JPS6310727A (ja) | 1988-01-18 |
| SE465305B (sv) | 1991-08-26 |
| DE3752112T2 (de) | 1998-01-15 |
| EP0252227A2 (en) | 1988-01-13 |
| EP0252227A3 (en) | 1990-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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