ES2106803T3 - Procedimiento para la preparacion de vinilglicina opticamente activa, en forma libre o protegida, a traves de una hidrolisis enzimatica, selectiva en cuanto a los enantiomeros. - Google Patents
Procedimiento para la preparacion de vinilglicina opticamente activa, en forma libre o protegida, a traves de una hidrolisis enzimatica, selectiva en cuanto a los enantiomeros.Info
- Publication number
- ES2106803T3 ES2106803T3 ES92114528T ES92114528T ES2106803T3 ES 2106803 T3 ES2106803 T3 ES 2106803T3 ES 92114528 T ES92114528 T ES 92114528T ES 92114528 T ES92114528 T ES 92114528T ES 2106803 T3 ES2106803 T3 ES 2106803T3
- Authority
- ES
- Spain
- Prior art keywords
- enantiomers
- vinylglycin
- enzymatic
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CUHFCSMYBZBTIT-UHFFFAOYSA-N 2-(ethenylamino)acetic acid Chemical compound OC(=O)CNC=C CUHFCSMYBZBTIT-UHFFFAOYSA-N 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 230000007062 hydrolysis Effects 0.000 title 1
- 238000006460 hydrolysis reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- RQVLGLPAZTUBKX-VKHMYHEASA-N L-vinylglycine Chemical compound C=C[C@H](N)C(O)=O RQVLGLPAZTUBKX-VKHMYHEASA-N 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
EL ENANTIOMERO D Y L DE LA VINILOGLICINA O DE LOS DERIVADOS DE LA VINILOGLICINA, SE PUEDE OBTENER DE ACUERDO CON LA INVENCION, CUANDO SE CONVIERTE LA MEZCLA RACEMICA DE LA VINILOGLICINA O DE LAS ETAPAS PREVIAS DE LA VINILOGLICINA EN MEDIO ACUOSO O ACUOSOORGANICO CON UNA ENCIMA ACTIVA PROTEOLITICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4128956 | 1991-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2106803T3 true ES2106803T3 (es) | 1997-11-16 |
Family
ID=6439560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92114528T Expired - Lifetime ES2106803T3 (es) | 1991-08-30 | 1992-08-26 | Procedimiento para la preparacion de vinilglicina opticamente activa, en forma libre o protegida, a traves de una hidrolisis enzimatica, selectiva en cuanto a los enantiomeros. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0529601B1 (es) |
| JP (1) | JPH05211891A (es) |
| AT (1) | ATE155819T1 (es) |
| DE (1) | DE59208719D1 (es) |
| ES (1) | ES2106803T3 (es) |
| GR (1) | GR3024726T3 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2399062C (en) * | 2000-02-11 | 2010-01-12 | Shire Biochem Inc. | Stereoselective synthesis of nucleoside analogues |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2927534A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung |
| US4806680A (en) * | 1986-03-17 | 1989-02-21 | Merck & Co., Inc. | 3-halovinylglycine antibacterial agents |
-
1992
- 1992-08-26 AT AT92114528T patent/ATE155819T1/de not_active IP Right Cessation
- 1992-08-26 EP EP92114528A patent/EP0529601B1/de not_active Expired - Lifetime
- 1992-08-26 ES ES92114528T patent/ES2106803T3/es not_active Expired - Lifetime
- 1992-08-26 DE DE59208719T patent/DE59208719D1/de not_active Expired - Fee Related
- 1992-08-28 JP JP4230480A patent/JPH05211891A/ja active Pending
-
1997
- 1997-09-16 GR GR970402369T patent/GR3024726T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE59208719D1 (de) | 1997-08-28 |
| EP0529601B1 (de) | 1997-07-23 |
| ATE155819T1 (de) | 1997-08-15 |
| GR3024726T3 (en) | 1997-12-31 |
| JPH05211891A (ja) | 1993-08-24 |
| EP0529601A1 (de) | 1993-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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