ES2107646T3 - Metodo y aparato para obtener protesis vasculares. - Google Patents

Metodo y aparato para obtener protesis vasculares.

Info

Publication number
ES2107646T3
ES2107646T3 ES93810297T ES93810297T ES2107646T3 ES 2107646 T3 ES2107646 T3 ES 2107646T3 ES 93810297 T ES93810297 T ES 93810297T ES 93810297 T ES93810297 T ES 93810297T ES 2107646 T3 ES2107646 T3 ES 2107646T3
Authority
ES
Spain
Prior art keywords
cells
tissue
carrier material
suspension
embedded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93810297T
Other languages
English (en)
Inventor
Werner Mueller-Glauser
Franz Rieser
Pedro Bittmann
Eric Dardel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sulzer Medizinaltechnik AG
Original Assignee
Sulzer Medizinaltechnik AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sulzer Medizinaltechnik AG filed Critical Sulzer Medizinaltechnik AG
Application granted granted Critical
Publication of ES2107646T3 publication Critical patent/ES2107646T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/062Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/18Use of ingredients of undetermined constitution or reaction products thereof
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92Method or apparatus for preparing or treating prosthetic
    • Y10S623/921Blood vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL METODO DE ACUERDO CON LA INVENCION, REPRESENTA UNA MEJORA DEL METODO CONOCIDO EN SI PARA LA FABRICACION DE PROTESIS, EL CUAL SE COMPONE DE UN PORTADOR ARTIFICIAL PREFORMADO, EN CUYA ZONA SUPERFICIAL SE IMPLANTAN CELULAS Y ASOCIACIONES DE CELULAS DEL PROPIO CUERPO, LAS CUALES DESPUES DE LA IMPLANTACION INICIAN UN REVESTIMIENTO DE LA SUPERFICIE DE LA PROTESIS O DE PARTES DE ESTA SUPERFICIE CON UNA CAPA VIVA. SE HA VISTO QUE TAMBIEN CUANDO LAS CELULAS Y ASOCIACIONES DE CELULAS A IMPLANTAR PROCEDEN DE UN TEJIDO, QUE ADEMAS DE ESTAS CELULAS TAMBIEN CONTIENE OTRAS CELULAS Y COMPONENTES DE TEJIDOS NO CELULARES, NO ES NECESARIO UN AISLAMIENTO DE LAS CELULAS DESEADAS ANTES DEL IMPLANTE. POR ESTE MOTIVO DE ACUERDO CON EL METODO DE LA INVENCION, SE PUEDE RENUNCIAR A UNA PREPARACION COMPLICADA Y DE LARGA DURACION DEL MATERIAL DEL TEJIDO EMPLEADO PARA EL AISLAMIENTO DE LAS CELULAS DESEADAS, TAL COMO SE DESCRIBE PARA EL CORRESPONDIENTE METODO CONFORME AL ESTADO DE LA TECNICA. EL MATERIAL DEL TEJIDO, EN ESENCIA SE TRITURA MECANICAMENTE Y SE SUSPENDE Y, CUANDO ES NECESARIO, ADICIONALMENTE DE MODO ENZIMATICO EN PARTICULAS DE TEJIDO, CUYAS DIMENSIONES ESTAN ENTRE LOS LIMITES MAS ESTRECHOS POSIBLES Y EL MATERIAL PORTANTE PREFORMADO SE TRATA CON LA SUSPENSION, PARA LO CUAL CON MATERIAL PORTANTE POROSO, SE FILTRA LA SUSPENSION POR EL MATERIAL, CON MATERIAL PORTANTE POCO POROSO O NO POROSO, SE LLEVA LA SUSPENSION POR CENTRIFUGACION A LA SUPERFICIE DEL MATERIAL PORTANTE. EN OPOSICION A LOS CORRESPONDIENTES METODOS SEGUN EL ESTADO DE LA TECNICA, SE PUEDE REALIZAR EL METODO DE ACUERDO CON LA INVENCION EN MUY POCO TIEMPO GRACIAS A LA MEJORA, POR TANTO, DIRECTAMENTE DURANTE LA OPERACION Y EN UN SISTEMA CERRADO.
ES93810297T 1992-05-11 1993-04-22 Metodo y aparato para obtener protesis vasculares. Expired - Lifetime ES2107646T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH149892 1992-05-11

Publications (1)

Publication Number Publication Date
ES2107646T3 true ES2107646T3 (es) 1997-12-01

Family

ID=4211862

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93810297T Expired - Lifetime ES2107646T3 (es) 1992-05-11 1993-04-22 Metodo y aparato para obtener protesis vasculares.

Country Status (10)

Country Link
US (1) US5634879A (es)
EP (1) EP0570331B1 (es)
JP (1) JPH0686809A (es)
KR (1) KR930023017A (es)
AT (1) ATE157856T1 (es)
AU (1) AU665813B2 (es)
DE (1) DE59307303D1 (es)
DK (1) DK0570331T3 (es)
ES (1) ES2107646T3 (es)
GR (1) GR3024888T3 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996001641A1 (de) * 1994-07-08 1996-01-25 Sulzer Medizinaltechnik Ag Verfahren zur herstellung von implantationsmaterialien
FR2722974B1 (fr) * 1994-07-29 1997-04-25 Marie Therese Zabot Procede de modification de la surface interne des protheses synthetiques utilisees en chirurgie vasculaire
US5976104A (en) * 1994-08-19 1999-11-02 Lifenet Research Foundation Recirculation method for cleaning essentially intact bone grafts using pressure mediated flow of solutions and bone grafts produced thereby
US6206917B1 (en) * 1997-05-02 2001-03-27 St. Jude Medical, Inc. Differential treatment of prosthetic devices
DE19834396C2 (de) * 1998-07-30 2000-07-13 Daimlerchrysler Aerospace Ag Verfahren zur Oberflächenbeschichtung medizinischer Implantate
EP1392333A2 (en) * 2000-08-03 2004-03-03 The University of Utah Research Foundation Manipulation of arterial-venous identity
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
KR100930139B1 (ko) 2001-12-07 2009-12-07 사이토리 테라퓨틱스, 인크. 처리된 리포애스퍼레이트 세포로 환자를 치료하기 위한시스템 및 방법
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7595043B2 (en) 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US8404229B2 (en) 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US20050048035A1 (en) 2001-12-07 2005-03-03 Fraser John K. Methods of using regenerative cells in the treatment of stroke and related diseases and disorders
US7744597B2 (en) 2002-06-26 2010-06-29 Lifenet Health Device and process for producing fiber products and fiber products produced thereby
US7494811B2 (en) 2003-05-01 2009-02-24 Lifenet Health In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
US20050055085A1 (en) * 2003-09-04 2005-03-10 Rivron Nicolas C. Implantable medical devices having recesses
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US7759120B2 (en) * 2005-03-02 2010-07-20 Kps Bay Medical, Inc. Seeding implantable medical devices with cells
US20060199265A1 (en) * 2005-03-02 2006-09-07 Wolf Michael F Seeding implantable medical devices with cells
WO2008124494A1 (en) * 2007-04-03 2008-10-16 The Cleveland Clinic Foundation Enrichment of tissue-derived adult stem cells based on retained extracellular matrix material
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
US20100112696A1 (en) * 2008-11-03 2010-05-06 Baxter International Inc. Apparatus And Methods For Processing Tissue To Release Cells
US8309343B2 (en) 2008-12-01 2012-11-13 Baxter International Inc. Apparatus and method for processing biological material
GB0901207D0 (en) 2009-01-26 2009-03-11 Innospec Ltd Chelating agents and methods relating thereto
AU2010242780B2 (en) 2009-05-01 2016-04-21 Puregraft Llc Systems, methods and compositions for optimizing tissue and cell enriched grafts
IT1400069B1 (it) * 2010-05-20 2013-05-17 Tremolada Dispositivo e metodo per la preparazione di tessuto, in particolare tessuto adiposo per trapianto ottenuto da materiale adiposo lobulare estratto tramite liposuzione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US5230693A (en) * 1985-06-06 1993-07-27 Thomas Jefferson University Implantable prosthetic device for implantation into a human patient having a surface treated with microvascular endothelial cells
CH670759A5 (es) * 1986-06-02 1989-07-14 Sulzer Ag
JP2678945B2 (ja) * 1989-04-17 1997-11-19 有限会社ナイセム 人工血管とその製造方法及び人工血管用基質
EP0444270A1 (en) * 1990-02-26 1991-09-04 Thomas Jefferson University Endothelial cell deposition device
NZ237832A (en) * 1990-04-17 1994-05-26 Curative Tech Inc Coating a prosthetic surface with mammalian cells
ATE117527T1 (de) * 1990-06-15 1995-02-15 Sulzer Medizinaltechnik Ag Verfahren zur herstellung von mit lebenden zellen beladenen, porösen, schlauchförmigen prothesen aus kunststoff.

Also Published As

Publication number Publication date
ATE157856T1 (de) 1997-09-15
JPH0686809A (ja) 1994-03-29
US5634879A (en) 1997-06-03
AU3677193A (en) 1993-11-18
AU665813B2 (en) 1996-01-18
DE59307303D1 (de) 1997-10-16
DK0570331T3 (da) 1997-12-15
EP0570331B1 (de) 1997-09-10
GR3024888T3 (en) 1998-01-30
KR930023017A (ko) 1993-12-18
EP0570331A1 (de) 1993-11-18

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