ES2109217T3 - Determinante peptidico asociado con la inmunidad. - Google Patents
Determinante peptidico asociado con la inmunidad.Info
- Publication number
- ES2109217T3 ES2109217T3 ES88307608T ES88307608T ES2109217T3 ES 2109217 T3 ES2109217 T3 ES 2109217T3 ES 88307608 T ES88307608 T ES 88307608T ES 88307608 T ES88307608 T ES 88307608T ES 2109217 T3 ES2109217 T3 ES 2109217T3
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- peptidic
- immunity
- motif
- followed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000036039 immunity Effects 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
SE PROPORCIONAN NUEVOS PEPTIDOS QUE IMPLICAN SECUENCIAS DE PROTEINAS DE INTERES, QUE INCLUYEN UN MOTIVO QUE COMPRENDE UN AMINOACIDO CARGADO, SEGUIDO POR DOS AMINOACIDOS HIDROFOBICOS, CONTINUADOS EN LA POSICION PROXIMA O LA SIGUIENTE POR UN AMINOACIDO POLAR, Y PUDIENDO ESTAR EL AMINOACIDO CARGADO O EL POLAR SUSTITUIDOS POR GLICINA. ESTOS PEPTIDOS SON ESTIMULANTES DE LAS CELULAS - T Y PERMITEN LA MODULACION DE LA RESPUESTA INMUNE, ILUSTRADA POR LA TOLERANCIA DEL HUESPED A PROTEINAS NEUROLOGICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8669487A | 1987-08-17 | 1987-08-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2109217T3 true ES2109217T3 (es) | 1998-01-16 |
Family
ID=22200262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88307608T Expired - Lifetime ES2109217T3 (es) | 1987-08-17 | 1988-08-17 | Determinante peptidico asociado con la inmunidad. |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP0304279B1 (es) |
| JP (1) | JPH01131124A (es) |
| AT (1) | ATE159952T1 (es) |
| CA (1) | CA1340012C (es) |
| DE (1) | DE3856059T2 (es) |
| ES (1) | ES2109217T3 (es) |
| GR (1) | GR3025673T3 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869054A (en) * | 1987-06-24 | 1999-02-09 | Autoimmune Inc. | Treatment of multiple sclerosis by oral administration of autoantigens |
| US5849298A (en) * | 1987-06-24 | 1998-12-15 | Autoimmune Inc. | Treatment of multiple sclerosis by oral administration of bovine myelin |
| US6039947A (en) * | 1987-06-24 | 2000-03-21 | Autoimmune, Inc. | Peptides derived from immunodominant epitopes of myelin basic protein |
| US5645820A (en) * | 1987-06-24 | 1997-07-08 | Autoimmune, Inc. | Treatment of autoimmune diseases by aerosol administration of autoantigens |
| US5641474A (en) * | 1987-06-24 | 1997-06-24 | Autoimmune, Inc. | Prevention of autoimmune diseases by aerosol administration of autoantigens |
| US5843445A (en) * | 1987-06-24 | 1998-12-01 | Autoimmune, Inc. | Method of treating rheumatoid arthritis with type II collagen |
| EP0359783B2 (en) † | 1987-06-24 | 2002-04-17 | Autoimmune, Inc. | Treatment of autoimmune diseases by oral administration of autoantigens |
| US6645504B1 (en) | 1987-06-24 | 2003-11-11 | Autoimmune Inc. | Bystander suppression of type I diabetes by oral administration of glucagon |
| US5776459A (en) * | 1989-07-19 | 1998-07-07 | Connetics Corporation | TCR V beta 5 peptides |
| US5614192A (en) * | 1989-07-19 | 1997-03-25 | Connective Therapeutics, Inc. | T cell receptor peptides as therapeutics for immune-related disease |
| US5547669A (en) | 1989-11-03 | 1996-08-20 | Immulogic Pharma Corp | Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I |
| US6066621A (en) * | 1989-12-10 | 2000-05-23 | Yeda Research And Development Co. Ltd. | Synthetic peptides for the treatment of myasthenia gravis |
| US6077509A (en) * | 1990-03-30 | 2000-06-20 | Autoimmune, Inc. | Peptide fragments of myelin basic protein |
| HUT69942A (en) * | 1990-10-15 | 1995-09-28 | Brigham & Womens Hospital | Treatment of autoimmun diseases by oral administration of autoantigenes |
| US5652211A (en) * | 1991-02-11 | 1997-07-29 | Biosynth S.R.L. | Peptides for neutralizing the toxicity of Lipid A |
| US5371186A (en) * | 1991-02-11 | 1994-12-06 | Biosynth S.R.L. | Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock |
| US5817629A (en) * | 1991-10-22 | 1998-10-06 | The Governors Of The University Of Alberta | Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients |
| US6252040B1 (en) | 1991-10-22 | 2001-06-26 | The Governors Of The University Of Alberta | Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients |
| US6329499B1 (en) | 1994-11-18 | 2001-12-11 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein |
| US6379670B1 (en) | 1994-11-18 | 2002-04-30 | Neurocrine Biosciences, Inc. | Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein |
| AU5296796A (en) * | 1995-02-28 | 1996-09-18 | National Jewish Center For Immunology And Respiratory Function | Peptidyl compounds comprising an itim motif which regulate hematopoietic function and their use |
| US5856446A (en) * | 1995-07-07 | 1999-01-05 | Autoimmune Inc. | Method of treating rheumatoid arthritis with low dose type II collagen |
| CN1301756A (zh) * | 1999-12-29 | 2001-07-04 | 复旦大学 | 一种新的多肽——髓磷脂p0蛋白14和编码这种多肽的多核苷酸 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0359783B2 (en) * | 1987-06-24 | 2002-04-17 | Autoimmune, Inc. | Treatment of autoimmune diseases by oral administration of autoantigens |
-
1988
- 1988-08-16 CA CA000574902A patent/CA1340012C/en not_active Expired - Fee Related
- 1988-08-17 DE DE3856059T patent/DE3856059T2/de not_active Expired - Fee Related
- 1988-08-17 ES ES88307608T patent/ES2109217T3/es not_active Expired - Lifetime
- 1988-08-17 AT AT88307608T patent/ATE159952T1/de not_active IP Right Cessation
- 1988-08-17 EP EP88307608A patent/EP0304279B1/en not_active Revoked
- 1988-08-17 EP EP97106788A patent/EP0805162A1/en not_active Withdrawn
- 1988-08-17 JP JP63203305A patent/JPH01131124A/ja active Pending
-
1997
- 1997-12-16 GR GR970403322T patent/GR3025673T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE159952T1 (de) | 1997-11-15 |
| EP0304279A2 (en) | 1989-02-22 |
| GR3025673T3 (en) | 1998-03-31 |
| DE3856059D1 (de) | 1997-12-11 |
| JPH01131124A (ja) | 1989-05-24 |
| EP0304279A3 (en) | 1990-05-16 |
| EP0304279B1 (en) | 1997-11-05 |
| CA1340012C (en) | 1998-08-25 |
| EP0805162A1 (en) | 1997-11-05 |
| DE3856059T2 (de) | 1998-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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