ES2109373T3 - Nueva proteina inhibidora de trombina a partir de garrapatas. - Google Patents

Nueva proteina inhibidora de trombina a partir de garrapatas.

Info

Publication number
ES2109373T3
ES2109373T3 ES92920588T ES92920588T ES2109373T3 ES 2109373 T3 ES2109373 T3 ES 2109373T3 ES 92920588 T ES92920588 T ES 92920588T ES 92920588 T ES92920588 T ES 92920588T ES 2109373 T3 ES2109373 T3 ES 2109373T3
Authority
ES
Spain
Prior art keywords
glu
phe
seq
pct
ticks
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92920588T
Other languages
English (en)
Inventor
Thomas Friedrich
Wolfgang Koerwer
Burkhard Kroeger
Siegfried Bialojan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2109373T3 publication Critical patent/ES2109373T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UNA NUEVA PROTEINA DE ACAROS (GARRAPATAS) INHIBIDORA DE TROMBINA CON UN PESO MOLECULAR DE QUIZAS 26.000 DALTON Y PRESENTA SECUENCIAS PARCIALES DE AMINOACIDOS VAL-ALA-LYS-PHE-ALA-XASN-SER-GLY-SER-GLU-THR-GLY, HIS, ALA-Y-PHE-GLU, ARG-VAL-SER-ASP-PHEGLU Y PHE-VAL-TYR-THR-ILE-GLU; DONDE X E Y PUEDEN SER IGUALES O DIFERENTES Y SON AMINOACIDOS PRESENTES NATURALMENTE. LA PROTEINA ES APROPIADA PARA EL TRATAMIENTO DE ENFERMEDADES.
ES92920588T 1991-10-31 1992-09-23 Nueva proteina inhibidora de trombina a partir de garrapatas. Expired - Lifetime ES2109373T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4136087A DE4136087A1 (de) 1991-10-31 1991-10-31 Neues thrombininhibitorisches protein aus zecken

Publications (1)

Publication Number Publication Date
ES2109373T3 true ES2109373T3 (es) 1998-01-16

Family

ID=6443924

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92920588T Expired - Lifetime ES2109373T3 (es) 1991-10-31 1992-09-23 Nueva proteina inhibidora de trombina a partir de garrapatas.

Country Status (10)

Country Link
US (1) US5585350A (es)
EP (1) EP0610246B1 (es)
JP (1) JPH07500827A (es)
AT (1) ATE161046T1 (es)
CA (1) CA2121246A1 (es)
DE (2) DE4136087A1 (es)
DK (1) DK0610246T3 (es)
ES (1) ES2109373T3 (es)
MX (1) MX9206055A (es)
WO (1) WO1993009231A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19917114B4 (de) * 1999-04-15 2004-05-06 Fritz Schäfer GmbH Kastenförmiger, einen Datenspeicher aufweisender Behälter aus Kunststoff
EP1879626A4 (en) * 2005-04-19 2011-03-23 Massachusetts Inst Technology AMPHIPHILIC POLYMERS AND METHOD FOR USE THEREOF
US10590302B2 (en) 2014-06-17 2020-03-17 Arkema Inc. High solids, low viscosity urethane-linkage containing latex and method of production thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2024697A1 (en) * 1989-09-07 1991-03-08 George P. Vlasuk Protein having anticoagulant properties
DE3931839A1 (de) * 1989-09-23 1991-04-04 Basf Ag Neue proteine und ihre herstellung

Also Published As

Publication number Publication date
US5585350A (en) 1996-12-17
EP0610246A1 (de) 1994-08-17
JPH07500827A (ja) 1995-01-26
DE59209064D1 (de) 1998-01-22
MX9206055A (es) 1993-04-01
WO1993009231A1 (de) 1993-05-13
DE4136087A1 (de) 1993-05-06
ATE161046T1 (de) 1997-12-15
EP0610246B1 (de) 1997-12-10
DK0610246T3 (da) 1998-01-12
CA2121246A1 (en) 1993-05-13

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