DK0842193T3 - Somatostatin-analoge cykliske peptider med hæmmende aktivitet på væksthormon - Google Patents

Somatostatin-analoge cykliske peptider med hæmmende aktivitet på væksthormon

Info

Publication number: DK0842193T3
Authority: DK; Denmark
Prior art keywords: growth hormone; inhibitory activity; cyclic peptides; pct; somatostatin analog
Prior art date: 1995-07-28

Application number

DK96927035T

Other languages

English (en)

Inventor

Romano Deghenghi

Original Assignee

Romano Deghenghi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-28

Filing date

1996-07-17

Publication date

2002-04-29

1996-07-17 Application filed by Romano Deghenghi filed Critical Romano Deghenghi

2002-04-29 Application granted granted Critical

2002-04-29 Publication of DK0842193T3 publication Critical patent/DK0842193T3/da

Links

102000018997 Growth Hormone Human genes 0.000 title abstract 2
108010051696 Growth Hormone Proteins 0.000 title abstract 2
239000000122 growth hormone Substances 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title abstract 2
102000001189 Cyclic Peptides Human genes 0.000 title 1
108010069514 Cyclic Peptides Proteins 0.000 title 1
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
230000001093 anti-cancer Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Food Science & Technology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK96927035T 1995-07-28 1996-07-17 Somatostatin-analoge cykliske peptider med hæmmende aktivitet på væksthormon DK0842193T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT95MI001670A IT1277391B1 (it)	1995-07-28	1995-07-28	Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita
PCT/EP1996/003149 WO1997005167A1 (en)	1995-07-28	1996-07-17	Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone

Publications (1)

Publication Number	Publication Date
DK0842193T3 true DK0842193T3 (da)	2002-04-29

Family

ID=11372091

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96927035T DK0842193T3 (da)	1995-07-28	1996-07-17	Somatostatin-analoge cykliske peptider med hæmmende aktivitet på væksthormon

Country Status (14)

Country	Link
US (1)	US5962409A (da)
EP (1)	EP0842193B1 (da)
JP (1)	JPH11510147A (da)
KR (1)	KR100321448B1 (da)
AT (1)	ATE213742T1 (da)
AU (1)	AU6700996A (da)
BR (1)	BR9609801A (da)
CA (1)	CA2227980A1 (da)
DE (1)	DE69619530T2 (da)
DK (1)	DK0842193T3 (da)
ES (1)	ES2171704T3 (da)
IT (1)	IT1277391B1 (da)
PT (1)	PT842193E (da)
WO (1)	WO1997005167A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6579967B1 (en)	1999-12-14	2003-06-17	The Salk Institute For Biological Studies	Receptor-selective somatostatin analogs
GB0018891D0 (en)	2000-08-01	2000-09-20	Novartis Ag	Organic compounds
US7019109B2 (en) *	2001-03-16	2006-03-28	The Salk Institute For Bilogical Studies	SSTR1-selective analogs
US20040121407A1 (en) *	2002-09-06	2004-06-24	Elixir Pharmaceuticals, Inc.	Regulation of the growth hormone/IGF-1 axis
CN1317031C (zh) *	2005-09-14	2007-05-23	上海第二医科大学附属新华医院	增强实体肿瘤细胞化疗敏感性的高效混合制剂
EP2275103B1 (en)	2005-11-21	2014-04-23	Novartis AG	mTOR inhibitors in the treatment of endocrine tumors
JP6211418B2 (ja) *	2011-09-04	2017-10-11	株式会社糖鎖工学研究所	糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4725577A (en) *	1985-04-25	1988-02-16	Administrators Of The Tulane Educational Fund	Biologically active lysine containing octapeptides
US4904642A (en) *	1985-09-12	1990-02-27	The Administrators Of The Tulane Educational Fund	Therapeutic somatostatin analogs
GR862206B (en) *	1985-09-12	1986-12-31	Univ Tulane	Therapeutic somatostatin analogs
IT1240643B (it) *	1990-05-11	1993-12-17	Mediolanum Farmaceutici Spa	Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
HU207104B (en) *	1991-01-25	1993-03-01	Biosignal Kutato Fejlesztoe Kf	Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
AU657770B2 (en) *	1991-06-03	1995-03-23	Mallinckrodt Medical, Inc.	Radiolabelled somatostatin derivatives, their preparation and use
WO1992021283A1 (en) *	1991-06-06	1992-12-10	Somanetics Corporation	Optical cerebral oximeter

1995
- 1995-07-28 IT IT95MI001670A patent/IT1277391B1/it active IP Right Grant
1996
- 1996-07-17 BR BR9609801A patent/BR9609801A/pt not_active IP Right Cessation
- 1996-07-17 AT AT96927035T patent/ATE213742T1/de not_active IP Right Cessation
- 1996-07-17 EP EP96927035A patent/EP0842193B1/en not_active Expired - Lifetime
- 1996-07-17 AU AU67009/96A patent/AU6700996A/en not_active Abandoned
- 1996-07-17 WO PCT/EP1996/003149 patent/WO1997005167A1/en not_active Ceased
- 1996-07-17 DE DE69619530T patent/DE69619530T2/de not_active Expired - Fee Related
- 1996-07-17 ES ES96927035T patent/ES2171704T3/es not_active Expired - Lifetime
- 1996-07-17 PT PT96927035T patent/PT842193E/pt unknown
- 1996-07-17 US US08/983,363 patent/US5962409A/en not_active Expired - Fee Related
- 1996-07-17 KR KR1019980700622A patent/KR100321448B1/ko not_active Expired - Fee Related
- 1996-07-17 JP JP9507186A patent/JPH11510147A/ja not_active Ceased
- 1996-07-17 CA CA002227980A patent/CA2227980A1/en not_active Abandoned
- 1996-07-17 DK DK96927035T patent/DK0842193T3/da active

Also Published As

Publication number	Publication date
ES2171704T3 (es)	2002-09-16
AU6700996A (en)	1997-02-26
ITMI951670A1 (it)	1997-01-28
EP0842193B1 (en)	2002-02-27
IT1277391B1 (it)	1997-11-10
KR100321448B1 (ko)	2002-07-31
US5962409A (en)	1999-10-05
ATE213742T1 (de)	2002-03-15
KR19990035961A (ko)	1999-05-25
ITMI951670A0 (it)	1995-07-28
BR9609801A (pt)	1999-07-06
CA2227980A1 (en)	1997-02-13
EP0842193A1 (en)	1998-05-20
PT842193E (pt)	2002-06-28
HK1008225A1 (en)	1999-05-07
JPH11510147A (ja)	1999-09-07
DE69619530T2 (de)	2002-08-08
WO1997005167A1 (en)	1997-02-13
DE69619530D1 (de)	2002-04-04

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FI950887L (fi)	1995-02-27	MAGE-3-geenistä peräisin oleva ja HLA-A1-proteiinin tarjoama eristetty nonapeptidi ja sen käytöt
EP0528858A4 (en)	1993-04-28	Inhibitors of dipeptidyl-aminopeptidase type iv
ATE133181T1 (de)	1996-02-15	Dehydrodidemnin b
AU7328601A (en)	2002-01-21	Skin care compositions containing silicone elastomers
BR9811956B1 (pt)	2010-06-01	naftiridinonas e composição farmacêutica compreendendo as mesmas.
NO962664D0 (no)	1996-06-21	Forbindelser med veksthormonfrigjörende egenskaper
DK0960127T3 (da)	2010-03-29	Isoleret dimert fibroblastaktiverende protein-alfa og anvendelser deraf
FI942228A0 (fi)	1994-05-13	Bacillus licheniformiksen x-amylaasipromoottorin variantista johdettu Bacillus-promoottori
ATE190352T1 (de)	2000-03-15	Dorsalgewebe beeinflussender faktor und zusammensetzungen
ATE364079T1 (de)	2007-06-15	Peptide mit gdp-austauschfaktorartiger wirkung, dafür kodierende nukleinsäuresequenzen, ihre herstellung und verwendung
BR9607335A (pt)	1997-11-25	Compostos 1-aril-2-acrilamino-etano e seu uso como neuroquinina especialmente antogonistas de neuroquinina 1
IT1299583B1 (it)	2000-03-16	Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica
ES2058479T3 (es)	1994-11-01	Compuestos peptidicos.
NO980296L (no)	1998-01-23	Forbedrede terapeutiske midler
BR9609801A (pt)	1999-07-06	Petídos cíclicos análogos de somatostina com atividade inibitória do desenvolvimento de hormónio
IL122606A (en)	2005-11-20	(S)-hydroxa-nitrile-lyase
MX9604762A (es)	1997-04-30	Nuevas sulfonamidas y procedimiento para su preparacion.
AU6722498A (en)	1998-09-22	Disubstituted biphenyloxazolines
ES2109373T3 (es)	1998-01-16	Nueva proteina inhibidora de trombina a partir de garrapatas.
FR2654430B1 (fr)	1995-01-06	Nouveaux derives de peptides, utilisables comme inhibiteurs des collagenases bacteriennes.
NO982151L (no)	1998-07-03	Hemoregulatoriske forbindelser
ITRM920045A0 (it)	1992-01-21	Composizioni farmaceutiche ad attivita' anti-aging.
ITRM920044A0 (it)	1992-01-21	Composizioni farmaceutiche ad attivita' anti-aging.
ITRM920043A0 (it)	1992-01-21	Composizioni farmaceutiche ad attivita' anti-aging.