ES2109606T3 - Compuestos de yodo vitamina d3 y metodo para su preparacion. - Google Patents

Compuestos de yodo vitamina d3 y metodo para su preparacion.

Info

Publication number
ES2109606T3
ES2109606T3 ES94303389T ES94303389T ES2109606T3 ES 2109606 T3 ES2109606 T3 ES 2109606T3 ES 94303389 T ES94303389 T ES 94303389T ES 94303389 T ES94303389 T ES 94303389T ES 2109606 T3 ES2109606 T3 ES 2109606T3
Authority
ES
Spain
Prior art keywords
compounds
vitamin
iodine compounds
preparation
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94303389T
Other languages
English (en)
Inventor
Hector Floyd Deluca
Rafal R Sicinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/060,230 external-priority patent/US5371249A/en
Priority claimed from US08/060,231 external-priority patent/US5380720A/en
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of ES2109606T3 publication Critical patent/ES2109606T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE VITAMINA D3 1(ALFA) ARACION DE COMPUESTOS DE VITAMINA D3 1(ALFA) YODADA. LOS COMPUESTOS DE 22 YODO IVAMENTE ALTA AFINIDAD DE ENLACE PARA EL RECEPTOR DE VITAMINA D DEMOSTRANDO SU POTENCIAL PARA ELEVADA ACTIVIDAD BIOLOGICA EN VIVO. ADEMAS, ESTOS COMPUESTOS INDUCEN RELATIVAMENTE ALTA DIFERENCIACION DE CELULAS MALIGNAS. TAMBIEN, ESTOS COMPUESTOS DE 22 STOS COMPUESTOS MUESTRAN POR TANTO ESPERANZA EN EL TRATAMIENTO DE LA OSTEOPOROSIS.
ES94303389T 1993-05-11 1994-05-11 Compuestos de yodo vitamina d3 y metodo para su preparacion. Expired - Lifetime ES2109606T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/060,230 US5371249A (en) 1993-05-11 1993-05-11 Iodo vitamin D3 compounds and method for preparing same
US08/060,231 US5380720A (en) 1993-05-11 1993-05-11 Iodo vitamin D3 compounds and method for preparing same

Publications (1)

Publication Number Publication Date
ES2109606T3 true ES2109606T3 (es) 1998-01-16

Family

ID=26739712

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94303389T Expired - Lifetime ES2109606T3 (es) 1993-05-11 1994-05-11 Compuestos de yodo vitamina d3 y metodo para su preparacion.

Country Status (5)

Country Link
EP (1) EP0624573B1 (es)
JP (1) JPH06329622A (es)
DE (1) DE69406183T2 (es)
DK (1) DK0624573T3 (es)
ES (1) ES2109606T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1777220A1 (en) * 2005-09-28 2007-04-25 Centre National de la Recherche Scientifique Vitamin D derivatives active on the vitamin D nuclear receptor, preparation and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3664909D1 (en) * 1985-05-30 1989-09-14 Taisho Pharmaceutical Co Ltd Vitamin d3 derivatives
EP0363211B1 (en) * 1988-10-05 1994-07-06 Asahi Kasei Kogyo Kabushiki Kaisha 1Alpha or 24R,25-Dihydroxy vitamin D3 derivatives, process for their production and assay method using the same
DK0528209T3 (da) * 1991-08-09 2000-03-27 Hoffmann La Roche Fremgangsmåde til fremstilling af mellemprodukter til D-Vitaminderivater og nye forbindelser

Also Published As

Publication number Publication date
DE69406183T2 (de) 1998-05-20
JPH06329622A (ja) 1994-11-29
EP0624573B1 (en) 1997-10-15
EP0624573A1 (en) 1994-11-17
DE69406183D1 (de) 1997-11-20
DK0624573T3 (da) 1997-12-01

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