ES2111517T3 - Sustratos poliarilicos activados y conjugados. - Google Patents

Sustratos poliarilicos activados y conjugados.

Info

Publication number
ES2111517T3
ES2111517T3 ES88304516T ES88304516T ES2111517T3 ES 2111517 T3 ES2111517 T3 ES 2111517T3 ES 88304516 T ES88304516 T ES 88304516T ES 88304516 T ES88304516 T ES 88304516T ES 2111517 T3 ES2111517 T3 ES 2111517T3
Authority
ES
Spain
Prior art keywords
substrates
polyarilic
conjugated
activated
solid substrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88304516T
Other languages
English (en)
Inventor
Brian Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RHONE POULENC RORER PHARMA
Aventis Pharmaceuticals Inc
Original Assignee
RHONE POULENC RORER PHARMA
Rhone Poulenc Rorer Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RHONE POULENC RORER PHARMA, Rhone Poulenc Rorer Pharmaceuticals Inc filed Critical RHONE POULENC RORER PHARMA
Application granted granted Critical
Publication of ES2111517T3 publication Critical patent/ES2111517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA INVENCION SE REFIERE A SUSTRATOS SOLIDOS Y A METODOS PARA SU PREPARACION EN LOS QUE SE CONSIGUE UNA FUNCIONALIZACION MEJORADA DE LOS SUSTRATOS SOLIDOS, PARA QUE SE PUEDAN OBTENER NIVELES MAS ALTOS DE UNION A UNA AMPLIA VARIEDAD DE GRUPOS. LA SUPERFICIE SE NITRA CON UN AGENTE DE NITRONIO, CON LO QUE LOS GRUPOS NITRO PUEDEN SER MODIFICADOS DE DIVERSAS MANERAS PARA QUE SIRVAN COMO SITIOS DE UNION. LOS SUSTRATOS SOLIDOS RESULTANTES ENCUENTRAN EMPLEO EN TERAPEUTICA, DIAGNOSIS Y TRATAMIENTO.
ES88304516T 1987-05-19 1988-05-18 Sustratos poliarilicos activados y conjugados. Expired - Lifetime ES2111517T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/051,917 US5241012A (en) 1987-05-19 1987-05-19 Activated and conjugated polystyrene substrate

Publications (1)

Publication Number Publication Date
ES2111517T3 true ES2111517T3 (es) 1998-03-16

Family

ID=21974183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88304516T Expired - Lifetime ES2111517T3 (es) 1987-05-19 1988-05-18 Sustratos poliarilicos activados y conjugados.

Country Status (9)

Country Link
US (4) US5241012A (es)
EP (1) EP0294059B1 (es)
JP (1) JPH0814583B2 (es)
AT (1) ATE162810T1 (es)
CA (1) CA1320190C (es)
DE (1) DE3856122T2 (es)
ES (1) ES2111517T3 (es)
GR (1) GR3026426T3 (es)
SG (1) SG64319A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933410A (en) * 1989-03-29 1990-06-12 Applied Immunesciences, Inc. Covalent attachment of macromolecules on substrate surfaces
JPH0372496A (ja) * 1989-05-26 1991-03-27 Applied Immune Sci Inc 固相多重ペプチド合成
US5286789A (en) * 1989-05-26 1994-02-15 Applied Immune Sciences, Inc. Solid phase multiple peptide synthesis
US6143508A (en) * 1989-06-29 2000-11-07 Rhone-Poulenc Rorer Pharmaceuticals Inc. Device and process for cell capture and recovery
CA1340565C (en) 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
US5622826A (en) * 1994-12-22 1997-04-22 Houston Advanced Research Center Method for immobilization of molecules on platinum solid support surfaces
WO1997001584A1 (en) * 1995-06-27 1997-01-16 University Of Akron, The Chemical modification of thermoplastic elastomers
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US6229603B1 (en) 1997-06-02 2001-05-08 Aurora Biosciences Corporation Low background multi-well plates with greater than 864 wells for spectroscopic measurements
US6063338A (en) * 1997-06-02 2000-05-16 Aurora Biosciences Corporation Low background multi-well plates and platforms for spectroscopic measurements
US5910287A (en) * 1997-06-03 1999-06-08 Aurora Biosciences Corporation Low background multi-well plates with greater than 864 wells for fluorescence measurements of biological and biochemical samples
US6426050B1 (en) 1997-05-16 2002-07-30 Aurora Biosciences Corporation Multi-well platforms, caddies, lids and combinations thereof
US6171780B1 (en) 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6517781B1 (en) 1997-06-02 2003-02-11 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6306642B1 (en) * 1997-11-24 2001-10-23 Quidel Corporation Enzyme substrate delivery and product registration in one step enzyme immunoassays
US6861035B2 (en) 1998-02-24 2005-03-01 Aurora Discovery, Inc. Multi-well platforms, caddies, lids and combinations thereof
US6369188B1 (en) 1998-03-27 2002-04-09 Polymeright, Inc. Polyfunctional urethane- or urea-containing oligomers and polymers prepared therefrom
US6627396B1 (en) * 1999-10-28 2003-09-30 The Regents Of The University Of California Influenza sensor
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20040151627A1 (en) * 2001-08-30 2004-08-05 Nelson Mary Anne Methods for covalently attaching nucleic acids to substrates
JP2005506839A (ja) * 2001-10-02 2005-03-10 ベクトン・ディキンソン・アンド・カンパニー 細胞外マトリックスおよび他の分子を使用する幹細胞の増殖および分化
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US20040062882A1 (en) * 2002-09-30 2004-04-01 Andrea Liebmann-Vinson Cell adhesion resisting surfaces
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
AU2004286253A1 (en) * 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Gel-shell beads with adsorbed or bound biomolecules
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
CA2544202C (en) 2003-10-29 2012-07-24 Bioarray Solutions Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
EP2055727A1 (en) * 2007-10-30 2009-05-06 Corning Incorporated High-capacity nanoparticulate immobilization surface
US9139456B2 (en) 2008-04-16 2015-09-22 The Curators Of The University Of Missouri Chelating compounds and immobilized tethered chelators
US7932326B2 (en) * 2008-04-16 2011-04-26 The University Of Kentucky Research Foundation Chelating compounds and immobilized tethered chelators
US9259670B2 (en) 2008-04-16 2016-02-16 The University Of Kentucky Research Foundation Flow-through filter to remove aluminum from medical solutions
JP6749685B2 (ja) * 2016-04-28 2020-09-02 株式会社マンダム 被験物質の皮膚感作性の検定方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL75125C (es) * 1943-09-02
GB993961A (en) * 1960-03-29 1965-06-02 Secr Defence Improvements in or relating to immunochemical polymer preparations
US3761299A (en) * 1970-10-13 1973-09-25 Eastman Kodak Co Treating polymeric surfaces
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3956219A (en) 1973-02-01 1976-05-11 Eli Lilly And Company Crosslinked polystyrene and substituted polystyrene compositions
US3860486A (en) 1973-05-24 1975-01-14 Owens Illinois Inc Insolubilizing enzymes with polystyrene derivatives
IL43366A (en) 1973-10-04 1976-09-30 Yeda Res & Dev Production of organic reagents for the acylation of organic compounds
AU483290B2 (en) * 1974-01-18 1976-07-15 Unisearch Limited Surface- grafted inert core copolymers for the preparation of water-insoluble enzymes
US3995094A (en) 1975-09-12 1976-11-30 Dynapol Corporation Halomethylation of polystyrene
CA1083508A (fr) 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
DE2711270A1 (de) * 1976-03-16 1977-09-22 Ici Ltd Organische materialien mit spezifisch reaktiven gruppen
US4226958A (en) 1979-08-27 1980-10-07 The Upjohn Company Process for preparing organo-arsenic derivatives of polystyrene and related polymers
CA1242862A (en) * 1983-11-23 1988-10-11 Brian R. Clark Derivatized polystyrene and other supports for spectroscopic studies
FR2580666B1 (fr) * 1985-04-19 1988-01-15 Elf Aquitaine Perfectionnement a l'immobilisation d'enzymes
GB8516081D0 (en) * 1985-06-25 1985-07-31 Ciba Geigy Ag Assay & purification of amyloid components
US4933410A (en) * 1989-03-29 1990-06-12 Applied Immunesciences, Inc. Covalent attachment of macromolecules on substrate surfaces

Also Published As

Publication number Publication date
US5241012A (en) 1993-08-31
US6361936B1 (en) 2002-03-26
GR3026426T3 (en) 1998-06-30
JPS6465456A (en) 1989-03-10
DE3856122T2 (de) 1998-05-14
CA1320190C (en) 1993-07-13
SG64319A1 (en) 2000-06-20
DE3856122D1 (de) 1998-03-05
EP0294059A2 (en) 1988-12-07
EP0294059A3 (en) 1990-12-05
JPH0814583B2 (ja) 1996-02-14
ATE162810T1 (de) 1998-02-15
EP0294059B1 (en) 1998-01-28
US6391980B1 (en) 2002-05-21
US5484852A (en) 1996-01-16

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