ES2111581T3 - Disoluciones estabilizadas de pvp-i. - Google Patents
Disoluciones estabilizadas de pvp-i.Info
- Publication number
- ES2111581T3 ES2111581T3 ES92106500T ES92106500T ES2111581T3 ES 2111581 T3 ES2111581 T3 ES 2111581T3 ES 92106500 T ES92106500 T ES 92106500T ES 92106500 T ES92106500 T ES 92106500T ES 2111581 T3 ES2111581 T3 ES 2111581T3
- Authority
- ES
- Spain
- Prior art keywords
- solution
- pvp
- dissolutions
- stabilized
- microbicidal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 title abstract 4
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- 239000011630 iodine Substances 0.000 abstract 2
- 230000003641 microbiacidal effect Effects 0.000 abstract 2
- 230000003113 alkalizing effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Hydrogenated Pyridines (AREA)
- Lubricants (AREA)
Abstract
SE DESCRIBEN SOLUCIONES DE POVIDONA-YODO (PVP-I) ESTABLES SEGUN LAS NORMAS U.S.P. Y UN METODO PARA PREPARARLAS. LA SOLUCION PVP-I INCLUYE UNA CANTIDAD EFICAZ MICROBICIDAL DE YODO DISPONIBLE Y UN AGENTE ALCALINIZANTE EN UNA CANTIDAD EFICAZ PARA MANTENER LA ESTABILIDAD DE LA SOLUCION SEGUN LAS NORMAS U.S.P. CUANDO SE ALMACENA DICHA SOLUCION EN UN CONTENEDOR DE CRISTAL, LA SOLUCION NO SE TAMPONA. EN REALIZACIONES PREFERIDAS, LA SOLUCION YODOFORA ES UNA SOLUCION PVP-I MICROBICIDAL PARA USO OFTALMICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/730,462 US5126127A (en) | 1991-07-16 | 1991-07-16 | Stabilized PVP-I solutions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2111581T3 true ES2111581T3 (es) | 1998-03-16 |
Family
ID=24935466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92106500T Expired - Lifetime ES2111581T3 (es) | 1991-07-16 | 1992-04-15 | Disoluciones estabilizadas de pvp-i. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5126127A (es) |
| EP (1) | EP0526695B1 (es) |
| JP (1) | JP3531945B2 (es) |
| KR (1) | KR100191873B1 (es) |
| AT (1) | ATE163130T1 (es) |
| AU (1) | AU646745B2 (es) |
| CA (1) | CA2062001C (es) |
| DE (1) | DE69224416T2 (es) |
| DK (1) | DK0526695T3 (es) |
| EG (1) | EG19995A (es) |
| ES (1) | ES2111581T3 (es) |
| FI (1) | FI114443B (es) |
| IE (1) | IE920796A1 (es) |
| IL (1) | IL101079A (es) |
| NO (1) | NO306379B1 (es) |
| ZA (1) | ZA921365B (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2685892A (en) * | 1991-10-08 | 1993-05-03 | Isp Investments Inc. | Method of treating blood |
| GB9306296D0 (en) * | 1993-03-26 | 1993-05-19 | Diversey Corp | Improved iodophors,production and use thereof |
| DE9312509U1 (de) * | 1993-08-20 | 1993-10-28 | Euro-Celtique S.A., Luxemburg/Luxembourg | Präparate zur äußeren Verabreichung von antiseptischen und/oder die Wundheilung fördernden Wirkstoffen |
| JP3108262B2 (ja) * | 1993-12-22 | 2000-11-13 | 明治製菓株式会社 | 研磨剤を含有しない口腔用半練状製剤 |
| US6605110B2 (en) | 2001-06-29 | 2003-08-12 | Advanced Cardiovascular Systems, Inc. | Stent with enhanced bendability and flexibility |
| EP1479379B1 (en) | 2003-05-19 | 2007-08-29 | Euro-Celtique S.A. | Dry liposomal PVP-iodine compositions |
| US20050262811A1 (en) * | 2004-05-27 | 2005-12-01 | Mahmood Mohiuddin | Sterilization process for iodine-containing antimicrobial topical solutions |
| AU2016253668B2 (en) * | 2006-03-14 | 2018-12-06 | Cls Pharmaceuticals, Inc. | Ophthalmic compositions comprising povidone-iodine |
| AU2013203462B2 (en) * | 2006-03-14 | 2016-08-04 | Cls Pharmaceuticals, Inc. | Ophthalmic compositions comprising povidone-iodine |
| US7767217B2 (en) | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| JP5083502B2 (ja) * | 2006-12-25 | 2012-11-28 | ライオン株式会社 | 眼科用組成物 |
| US20080172032A1 (en) * | 2007-01-11 | 2008-07-17 | James Pitzer Gills | Method for preventing tissue damage associated with irrigation of tissue with an antimicrobial solution |
| EP3777536A1 (en) * | 2008-06-12 | 2021-02-17 | Takeda Pharmaceutical Company Limited | Povidone iodine, a novel alternative preservative for ophthalmic compositions |
| TWI618539B (zh) * | 2009-12-15 | 2018-03-21 | 遠景生物製藥股份有限公司 | 無刺激性眼用聚乙烯吡咯啶酮-碘組成物 |
| JP5367597B2 (ja) | 2010-01-18 | 2013-12-11 | 株式会社オフテクス | コンタクトレンズ洗浄用有核錠及びそれを含むコンタクトレンズ洗浄用製剤、並びにコンタクトレンズ洗浄方法 |
| GB201114725D0 (en) | 2011-08-25 | 2011-10-12 | Altacor Ltd | Ophthalmic formulations |
| TW202023575A (zh) * | 2011-09-16 | 2020-07-01 | 美商遠景生物製藥股份有限公司 | 安定之普維酮—碘組成物 |
| CN113679697A (zh) | 2012-09-12 | 2021-11-23 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| DK3181119T3 (da) | 2012-09-12 | 2019-09-16 | Novaliq Gmbh | Semifluorerede alkansammensætninger til anvendelse ved behandling af keratoconjunctivitis sicca |
| US20180200289A1 (en) * | 2015-07-02 | 2018-07-19 | Veloce Biopharma, Llc | Novel ophthalmic composition and methods of use |
| US9770466B2 (en) | 2015-07-02 | 2017-09-26 | Veloce Biopharma, Llc | Ophthalmic composition and methods of use |
| CN108348777B (zh) | 2015-09-30 | 2020-04-28 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| CA3058097C (en) | 2017-04-21 | 2024-01-02 | Novaliq Gmbh | Iodine compositions |
| IT201700068170A1 (it) * | 2017-06-20 | 2018-12-20 | Iromed Group S R L | Composizione disinfettante per uso oftalmico |
| WO2019040051A1 (en) * | 2017-08-22 | 2019-02-28 | Veloce Biopharma, Llc | NOVEL OPHTHALMIC COMPOSITION AND METHODS OF USE |
| EP3512522B1 (en) | 2017-09-02 | 2025-11-12 | IVIEW Therapeutics, Inc. | In situ gel-forming pharmaceutical compositions and uses thereof for sinus diseases |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| JP2021522219A (ja) | 2018-04-27 | 2021-08-30 | ノバリック ゲーエムベーハー | 緑内障の治療のためのタフルプロストを含む眼科用組成物 |
| SG11202102820VA (en) | 2018-10-12 | 2021-04-29 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| KR20200081160A (ko) | 2018-12-27 | 2020-07-07 | 유한회사 플루켐 | 염화나트륨 함유 포비돈 요오드 안정 조성물 및 방법 |
| JP2022538711A (ja) | 2019-06-10 | 2022-09-06 | ファイアブリック・ファーマ・リミテッド | 粘膜へのポビドンヨードの局所適用を使用する高病原性ウイルスによる感染の予防 |
| CN114502205B (zh) * | 2019-08-18 | 2024-08-06 | 艾威药业公司 | 含稀聚维酮碘制剂的稳定药品 |
| IL298888A (en) * | 2020-06-10 | 2023-02-01 | Firebrick Pharma Ltd | Preparations for the treatment of the virus |
| AU2021203846B2 (en) * | 2021-06-10 | 2022-11-24 | Firebrick Pharma Limited | Virucidal formulations containing povidone-iodine |
| KR102434736B1 (ko) | 2021-11-04 | 2022-08-23 | (주)씨에스하이테크플러스 | 신재생에너지를 이용한 에너지자립형 냉난방 시스템 및 방법 |
| KR102917044B1 (ko) * | 2023-06-22 | 2026-01-23 | 주식회사 퍼슨헬스케어 | 세정용 포비돈요오드 조성물 및 그 제조방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4364929A (en) * | 1979-04-02 | 1982-12-21 | The Purdue Frederick Company | Germicidal colloidal lubricating gels and method of producing the same |
| SE7902893L (sv) * | 1979-04-02 | 1980-10-03 | Astra Chem Prod Ab | Desinfektionsmedel |
| US4401651A (en) * | 1979-04-18 | 1983-08-30 | Knutson Richard A | Wound-healing compositions containing povidone-iodine |
| US4526751A (en) * | 1983-12-09 | 1985-07-02 | Gartner William J | Germicidal solutions effective for solid surface disinfection |
| WO1989000044A1 (fr) * | 1987-07-07 | 1989-01-12 | Santen Pharmaceutical Co., Ltd. | Larme artificielle |
| CA1303503C (en) * | 1987-11-10 | 1992-06-16 | Marc Plamondon | Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex |
| JPH0662417B2 (ja) * | 1987-12-25 | 1994-08-17 | 参天製薬株式会社 | 抗アレルギー点眼液 |
| US4939272A (en) * | 1989-05-05 | 1990-07-03 | Gaf Chemicals Corporation | Water soluble complexes of polyvinylpyrrolidone, hydrogen chloride and iodine and process for making the same |
| NL9002049A (nl) * | 1990-09-18 | 1992-04-16 | Dagra Pharma Bv | Oogheelkundig preparaat dat een povidon-joodoplossing bevat. |
-
1991
- 1991-07-16 US US07/730,462 patent/US5126127A/en not_active Expired - Lifetime
-
1992
- 1992-02-25 ZA ZA921365A patent/ZA921365B/xx unknown
- 1992-02-27 CA CA002062001A patent/CA2062001C/en not_active Expired - Fee Related
- 1992-02-27 IL IL10107992A patent/IL101079A/xx not_active IP Right Cessation
- 1992-03-12 IE IE079692A patent/IE920796A1/en not_active IP Right Cessation
- 1992-03-23 JP JP06448592A patent/JP3531945B2/ja not_active Expired - Fee Related
- 1992-04-15 DE DE69224416T patent/DE69224416T2/de not_active Expired - Fee Related
- 1992-04-15 EP EP92106500A patent/EP0526695B1/en not_active Expired - Lifetime
- 1992-04-15 AT AT92106500T patent/ATE163130T1/de not_active IP Right Cessation
- 1992-04-15 ES ES92106500T patent/ES2111581T3/es not_active Expired - Lifetime
- 1992-04-15 DK DK92106500T patent/DK0526695T3/da active
- 1992-06-15 KR KR1019920010355A patent/KR100191873B1/ko not_active Expired - Fee Related
- 1992-06-22 FI FI922906A patent/FI114443B/fi not_active IP Right Cessation
- 1992-07-02 AU AU19427/92A patent/AU646745B2/en not_active Ceased
- 1992-07-14 EG EG39192A patent/EG19995A/xx active
- 1992-07-15 NO NO922793A patent/NO306379B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0526695A1 (en) | 1993-02-10 |
| AU1942792A (en) | 1994-01-13 |
| DE69224416T2 (de) | 1998-07-30 |
| ATE163130T1 (de) | 1998-02-15 |
| DK0526695T3 (da) | 1998-09-23 |
| NO306379B1 (no) | 1999-11-01 |
| NO922793L (no) | 1993-01-18 |
| IL101079A0 (en) | 1992-11-15 |
| EG19995A (en) | 1997-01-30 |
| CA2062001A1 (en) | 1993-01-17 |
| NO922793D0 (no) | 1992-07-15 |
| FI114443B (fi) | 2004-10-29 |
| JP3531945B2 (ja) | 2004-05-31 |
| CA2062001C (en) | 1999-03-02 |
| US5126127A (en) | 1992-06-30 |
| KR930001914A (ko) | 1993-02-22 |
| IE920796A1 (en) | 1993-01-27 |
| IL101079A (en) | 1997-01-10 |
| DE69224416D1 (de) | 1998-03-19 |
| EP0526695B1 (en) | 1998-02-11 |
| FI922906A0 (fi) | 1992-06-22 |
| FI922906L (fi) | 1993-01-17 |
| AU646745B2 (en) | 1994-03-03 |
| KR100191873B1 (ko) | 1999-06-15 |
| ZA921365B (en) | 1992-11-25 |
| JPH0570356A (ja) | 1993-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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