ES2114576T3 - Procedimiento para la preparacion de 5-cloroimidazol-4-carbaldehidos sustituidos en posicion 2. - Google Patents
Procedimiento para la preparacion de 5-cloroimidazol-4-carbaldehidos sustituidos en posicion 2.Info
- Publication number
- ES2114576T3 ES2114576T3 ES93111315T ES93111315T ES2114576T3 ES 2114576 T3 ES2114576 T3 ES 2114576T3 ES 93111315 T ES93111315 T ES 93111315T ES 93111315 T ES93111315 T ES 93111315T ES 2114576 T3 ES2114576 T3 ES 2114576T3
- Authority
- ES
- Spain
- Prior art keywords
- carbaldehydes
- chloroimidazole
- procedure
- preparation
- pocl3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 7
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 4
- 229910019213 POCl3 Inorganic materials 0.000 abstract 2
- BNNOTXZTUYAFBL-UHFFFAOYSA-N 2-butyl-1,4-dihydroimidazol-5-one Chemical compound CCCCC1=NCC(=O)N1 BNNOTXZTUYAFBL-UHFFFAOYSA-N 0.000 abstract 1
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 abstract 1
- OHVWCRAXBOZMMG-UHFFFAOYSA-N 5-chloro-1h-imidazole-4-carbaldehyde Chemical class ClC=1N=CNC=1C=O OHVWCRAXBOZMMG-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO NUEVO PARA LA FABRICACION DE 5-CLOROIMIDAZOL-4CARBALDEHIDO SUSTITUIDOS EN POSICION 2 DE FORMULA (I). ESTOS COMPUESTOS SON PRODUCTOS INTERMEDIOS VALIOSOS PARA LA OBTENCION DE PRODUCTOS FARMACEUTICOS REDUCTORES DE LA PRESION SANGUINEA O DE COMPUESTOS CON ACCION HERBICIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH223992 | 1992-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2114576T3 true ES2114576T3 (es) | 1998-06-01 |
Family
ID=4229109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93111315T Expired - Lifetime ES2114576T3 (es) | 1992-07-16 | 1993-07-14 | Procedimiento para la preparacion de 5-cloroimidazol-4-carbaldehidos sustituidos en posicion 2. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5442076A (es) |
| EP (1) | EP0579212B1 (es) |
| JP (1) | JP3500660B2 (es) |
| KR (1) | KR100286578B1 (es) |
| AT (1) | ATE165090T1 (es) |
| CA (1) | CA2100637C (es) |
| DE (1) | DE59308400D1 (es) |
| DK (1) | DK0579212T3 (es) |
| ES (1) | ES2114576T3 (es) |
| HU (1) | HU217189B (es) |
| RU (1) | RU2103262C1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565577A (en) * | 1992-09-23 | 1996-10-15 | Smithkline Beecham Corporation | Process for preparing 1-alkyaryl-2-alkyl-5-formylimidazole |
| ES2108894T3 (es) * | 1993-03-12 | 1998-01-01 | Lonza Ag | Procedimiento para la preparacion de 5-cloroimidazoles eventualmente sustituidos en posicion 2. |
| US5484939A (en) * | 1993-03-12 | 1996-01-16 | Lonza Ltd. | 2-substituted 5-chlorimidazoles |
| CA2175420C (en) * | 1995-05-17 | 2007-04-10 | Gareth Griffiths | Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes |
| JP4103149B2 (ja) * | 1996-01-05 | 2008-06-18 | ロンザ リミテッド | 2−置換5−クロロイミダゾール−4−カルブアルデヒドの製造方法 |
| JP2008535911A (ja) * | 2005-04-15 | 2008-09-04 | ディシュマン・ファーマシューティカルズ・アンド・ケミカルズ・リミテッド | 2−置換4−クロロ−5−ホルミルイミダゾール及び5−ホルミルイミダゾールの調製 |
| CN101838242B (zh) * | 2010-05-16 | 2015-07-15 | 浙江工业大学 | 2-正丁基-4-氯-5-甲酰基咪唑的合成方法 |
| CN103214420B (zh) * | 2013-04-26 | 2015-04-08 | 台州职业技术学院 | 一种2-丁基-4-氯-5-甲酰基咪唑的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU525676A1 (ru) * | 1975-04-15 | 1976-08-25 | Ленинградский Ордена Трудового Красного Знамени Технологический Институт Им.Ленсовета | Способ получени -алкил/арил/4-формил-5-хлоримидазолов |
| IL53783A (en) * | 1977-02-03 | 1982-08-31 | American Cyanamid Co | Imidazo(1,5-d)-as-triazine-4 (3h)-(thi)one derivatives,their preparation and pharmaceutical compositions containing them |
| JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
| US5120854A (en) * | 1987-08-17 | 1992-06-09 | American Cyanamid Company | Benzenesulfonyl carboxamide compounds and intermediate compounds |
| JPH03223281A (ja) * | 1989-12-01 | 1991-10-02 | Glaxo Group Ltd | ベンゾチオフェン誘導体 |
| DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
-
1993
- 1993-07-06 RU RU93047797A patent/RU2103262C1/ru active
- 1993-07-13 JP JP17339293A patent/JP3500660B2/ja not_active Expired - Fee Related
- 1993-07-14 DK DK93111315.3T patent/DK0579212T3/da active
- 1993-07-14 AT AT93111315T patent/ATE165090T1/de active
- 1993-07-14 EP EP93111315A patent/EP0579212B1/de not_active Expired - Lifetime
- 1993-07-14 DE DE59308400T patent/DE59308400D1/de not_active Expired - Lifetime
- 1993-07-14 ES ES93111315T patent/ES2114576T3/es not_active Expired - Lifetime
- 1993-07-15 US US08/092,052 patent/US5442076A/en not_active Expired - Lifetime
- 1993-07-15 CA CA002100637A patent/CA2100637C/en not_active Expired - Lifetime
- 1993-07-15 KR KR1019930013310A patent/KR100286578B1/ko not_active Expired - Fee Related
- 1993-07-16 HU HU9302056A patent/HU217189B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100286578B1 (ko) | 2001-04-16 |
| HUT65120A (en) | 1994-04-28 |
| RU2103262C1 (ru) | 1998-01-27 |
| DE59308400D1 (de) | 1998-05-20 |
| HU9302056D0 (en) | 1993-11-29 |
| CA2100637C (en) | 2003-12-09 |
| ATE165090T1 (de) | 1998-05-15 |
| EP0579212B1 (de) | 1998-04-15 |
| US5442076A (en) | 1995-08-15 |
| JP3500660B2 (ja) | 2004-02-23 |
| EP0579212A1 (de) | 1994-01-19 |
| CA2100637A1 (en) | 1994-01-17 |
| DK0579212T3 (da) | 1998-05-11 |
| KR940002230A (ko) | 1994-02-16 |
| JPH06157473A (ja) | 1994-06-03 |
| HU217189B (hu) | 1999-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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