ES2116906B1 - Anticuerpo monocional pc2.27 asociado a tumores. - Google Patents

Anticuerpo monocional pc2.27 asociado a tumores.

Info

Publication number
ES2116906B1
ES2116906B1 ES9600750A ES9600750A ES2116906B1 ES 2116906 B1 ES2116906 B1 ES 2116906B1 ES 9600750 A ES9600750 A ES 9600750A ES 9600750 A ES9600750 A ES 9600750A ES 2116906 B1 ES2116906 B1 ES 2116906B1
Authority
ES
Spain
Prior art keywords
tumors
antibody
immunized
cells
monotional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9600750A
Other languages
English (en)
Other versions
ES2116906A1 (es
Inventor
Avila Miguel Quintanilla
Amat Carlos Gamallo
Solinis Alberto Gandarillas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Universidad Autonoma de Madrid
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Universidad Autonoma de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC, Universidad Autonoma de Madrid filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES9600750A priority Critical patent/ES2116906B1/es
Priority to PCT/ES1997/000078 priority patent/WO1997036930A1/es
Publication of ES2116906A1 publication Critical patent/ES2116906A1/es
Application granted granted Critical
Publication of ES2116906B1 publication Critical patent/ES2116906B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ANTICUERPO MONOCLONAL PC2.27 ASOCIADO A TUMORES. LA INVENCION ES, ESPECIFICAMENTE, UN LINEA CELULAR DE HIBRIDOMA, DENOMINADA COMO GQPC2.27, QUE PRODUCE UN ANTICUERPO IGM, DENOMINADO ABREVIADAMENTE PC2.97, QUE RECONOCE UN ANTIGENO LOCALIZADO EN EL CITOESQUELETO CELULAR DE PESO MOLECULAR APARENTE: 56 KDA (RATON) Y 51 KDA (HUMANO). EL HIDRODOMA FUE OBTENIDO POR LA FUSION DE CELULAS EXTRAIDAS DEL BRAZO DE RATAS WISTAR INMUNIZADAS Y DE CELULAS DE MIELOMA DE LA LINEA ESTABLECIDA P3X63-AG8653. LAS RATAS FUERON INMUNIZADAS CON CELULAS ENTERAS DE EPIDERMIS DE RATON TRANSFORMADAS IN VITRO POR EL CARCINOGENO DIMETILBENZANTRACENO (LINEA CELULAR PDV).
ES9600750A 1996-03-28 1996-03-28 Anticuerpo monocional pc2.27 asociado a tumores. Expired - Lifetime ES2116906B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES9600750A ES2116906B1 (es) 1996-03-28 1996-03-28 Anticuerpo monocional pc2.27 asociado a tumores.
PCT/ES1997/000078 WO1997036930A1 (es) 1996-03-28 1997-03-24 Anticuerpo monoclonal pc2.27 asociado a tumores

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9600750A ES2116906B1 (es) 1996-03-28 1996-03-28 Anticuerpo monocional pc2.27 asociado a tumores.

Publications (2)

Publication Number Publication Date
ES2116906A1 ES2116906A1 (es) 1998-07-16
ES2116906B1 true ES2116906B1 (es) 1999-03-01

Family

ID=8294356

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9600750A Expired - Lifetime ES2116906B1 (es) 1996-03-28 1996-03-28 Anticuerpo monocional pc2.27 asociado a tumores.

Country Status (2)

Country Link
ES (1) ES2116906B1 (es)
WO (1) WO1997036930A1 (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722895A (en) * 1984-09-25 1988-02-02 The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services Synthetic peptides for the production of specific keratin protein antibodies
US5158893A (en) * 1986-12-11 1992-10-27 Peralta Cancer Research Institute Methods and compositions for screening carcinomas
SE470273B (sv) * 1990-09-24 1993-12-20 Idl Immunodeveloplab Ab Cytokeratinfragment, deras framställning och användning, framställning av monoklonala antikroppar och testkit för epitelialcancer

Also Published As

Publication number Publication date
WO1997036930A1 (es) 1997-10-09
ES2116906A1 (es) 1998-07-16

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