ES2117628T3 - Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este. - Google Patents
Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este.Info
- Publication number
- ES2117628T3 ES2117628T3 ES90310671T ES90310671T ES2117628T3 ES 2117628 T3 ES2117628 T3 ES 2117628T3 ES 90310671 T ES90310671 T ES 90310671T ES 90310671 T ES90310671 T ES 90310671T ES 2117628 T3 ES2117628 T3 ES 2117628T3
- Authority
- ES
- Spain
- Prior art keywords
- hydroxylamine
- reducing agent
- reagent containing
- narrow distribution
- seed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 3
- 239000000084 colloidal system Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 3
- 239000003638 chemical reducing agent Substances 0.000 abstract 3
- 239000002184 metal Substances 0.000 abstract 3
- 229910052751 metal Inorganic materials 0.000 abstract 3
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
- 229910052737 gold Inorganic materials 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/0004—Preparation of sols
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/0004—Preparation of sols
- B01J13/0043—Preparation of sols containing elemental metal
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Dispersion Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Manufacture Of Metal Powder And Suspensions Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Colloid Chemistry (AREA)
Abstract
UN METODO PARA PRODUCIR UN REACTIVO QUE CONTENGA UNA DISTRIBUCION ESTRECHA DE PARTICULAS DE SOL METALICAS DE TAMAÑO SELECCIONADO PARA SER UTILIZADO COMO REACTIVOS DE INMUNOENSAYOS O COMO MARCADORES DE ETIQUETAS O CELULAS PARA TECNICAS MICROSCOPICAS. EL NUEVO PROCESO DE SOL METALICO DE SEMBRADO COLOIDAL DE LOS APLICANTES DE LA PATENTE INCLUYE: LA PREPARACION DE NUCLEOS DE ORO O SIMIENTE UTILIZANDO UN AGENTE REDUCTOR FUERTE EN PRESENCIA DE UN AGENTE ESTABILIZADOR SELECCIONADO DE MODO QUE NINGUNO DE LOS AGENTES AFECTARA DE MANERA APRECIABLE EL CRECIMIENTO SUBSIGUIENTE DE LA SIMIENTE PRODUCIDA; LA PREPARACION DE PARTICULAS DE SOL METALICAS DE DIFERENTES TAMAÑOS UTILIZANDO LA SIMIENTE PREPARADA SEGUN EL METODO DE LOS APLICANTES DE LA PATENTE Y DE HIDROXILAMINA O CITRATO SODICO COMO AGENTE REDUCTOR; INACTIVANDO LA HIDROXALAMINA Y SUS DERIVADOS DE REACCION CUANDO LA HIDROXILAMINA ES EL AGENTE REDUCTOR; RECUBRIMIENTO DE LAS PARTICULAS CON UN MATERIAL SELECCIONADO; Y UTILIZACION DE LECHE DESNATADA COMO POSTRECUBRIDOR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41518489A | 1989-09-29 | 1989-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2117628T3 true ES2117628T3 (es) | 1998-08-16 |
Family
ID=23644702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90310671T Expired - Lifetime ES2117628T3 (es) | 1989-09-29 | 1990-09-28 | Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0426300B1 (es) |
| JP (1) | JPH03206959A (es) |
| AT (1) | ATE166975T1 (es) |
| CA (1) | CA2026409C (es) |
| DE (1) | DE69032363T2 (es) |
| DK (1) | DK0426300T3 (es) |
| ES (1) | ES2117628T3 (es) |
| GR (1) | GR1000722B (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2347034A1 (es) * | 2009-04-21 | 2010-10-22 | Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina | Procedimiento para la obtencion de nanoparticulas metalicas. |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW239881B (es) * | 1992-12-22 | 1995-02-01 | Sienna Biotech Inc | |
| US6200820B1 (en) | 1992-12-22 | 2001-03-13 | Sienna Biotech, Inc. | Light scatter-based immunoassay |
| US5851777A (en) * | 1996-02-05 | 1998-12-22 | Dade Behring Inc. | Homogeneous sol-sol assay |
| AU6016999A (en) * | 1998-04-20 | 1999-12-13 | University Of North Carolina At Chapel Hill, The | Nanometer sized particles containing a reactive monolayer adsorbed thereon and methods of making the same |
| IL126776A (en) | 1998-10-27 | 2001-04-30 | Technion Res & Dev Foundation | A method of investing gold |
| US7364920B2 (en) | 1999-10-27 | 2008-04-29 | Technion Research And Development Foundation Ltd. | Method for gold deposition |
| AU1945901A (en) | 1999-12-03 | 2001-06-12 | Surromed, Inc. | Hydroxylamine seeding of colloidal metal nanoparticles |
| CA2537199C (en) | 2003-08-28 | 2011-11-29 | Tama-Tlo, Ltd. | Precious metal colloid, precious metal microparticle, composition, and process for producing the precious metal microparticle |
| WO2008103824A1 (en) * | 2007-02-23 | 2008-08-28 | Chinese Academy Of Inspection And Quarantine (Caiq) | Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection |
| GB0724870D0 (en) * | 2007-12-21 | 2008-01-30 | Univ Lincoln The | Preparation of metal colloids |
| JP5035622B2 (ja) * | 2008-01-11 | 2012-09-26 | 積水化学工業株式会社 | 着色ラテックス |
| CN102539773B (zh) * | 2011-12-31 | 2014-07-16 | 上海凯创生物技术有限公司 | 氯胺酮胶体金检测试剂盒及其制备方法 |
| DE102013108664A1 (de) | 2013-08-09 | 2015-02-12 | Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh | Oberflächenmodifizierte Metallkolloide und ihre Herstellung |
| EP2835402B1 (en) | 2013-08-09 | 2020-07-08 | Leibniz-Institut für Neue Materialien gemeinnützige GmbH | Formation of surface modified metal colloids |
| EP3165923B1 (en) | 2014-07-01 | 2020-02-05 | NIPPON STEEL Chemical & Material Co., Ltd. | Marker, immunoassay method, immunoassay reagent, method for assaying analyte, analyte measurement kit, and lateral- flow chromatographic test strip |
| WO2016002742A1 (ja) | 2014-07-01 | 2016-01-07 | 新日鉄住金化学株式会社 | 樹脂-金属複合体、標識物質、免疫学的測定法、免疫学的測定用試薬、アナライトの測定方法、アナライト測定用キット、及び、ラテラルフロー型クロマト用テストストリップ |
| CN105067807B (zh) * | 2015-04-30 | 2018-01-09 | 珠海丽珠试剂股份有限公司 | 一种免疫检测用纳米胶体金的制备方法 |
| US11215611B2 (en) | 2015-07-11 | 2022-01-04 | Nippon Steel Chemical & Material Co., Ltd. | Resin-platinum composite and usage thereof |
| CN105436516B (zh) * | 2015-12-03 | 2018-06-08 | 南昌大学 | 可控粒径高吸光强度多枝状胶体金纳米粒子的制备方法 |
| KR102640613B1 (ko) | 2016-12-28 | 2024-02-26 | 닛테츠 케미컬 앤드 머티리얼 가부시키가이샤 | 금속-수지 복합체 및 그 이용 |
| CN111229321A (zh) * | 2020-01-16 | 2020-06-05 | 吉林大学 | 一种具有强催化功能的谷胱甘肽保护的铂金合金纳米簇、制备方法及其应用 |
| CN112094699B (zh) * | 2020-09-27 | 2023-03-28 | 广西壮族自治区林业科学研究院 | 一种樟树纯露的提取方法 |
| CN115575623B (zh) * | 2022-12-06 | 2023-03-28 | 深圳市卓润生物科技有限公司 | 胶体金及其制备方法和应用 |
| CN116217991B (zh) * | 2023-03-09 | 2024-02-27 | 四川大学 | 一种圆偏振发光薄膜制备方法和应用 |
| CN116930482B (zh) * | 2023-07-31 | 2025-05-09 | 山东康华生物医疗科技股份有限公司 | 一种胃幽门螺旋杆菌抗原检测试纸条用的胶体金制备方法及试纸条的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7807532A (nl) * | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
| JPS63307208A (ja) * | 1987-06-08 | 1988-12-14 | Chiyoda Chem Eng & Constr Co Ltd | 貴金属微粉末の製造方法 |
| US4859612A (en) * | 1987-10-07 | 1989-08-22 | Hygeia Sciences, Inc. | Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite |
| NL8702769A (nl) * | 1987-11-19 | 1989-06-16 | Holland Biotechnology | Werkwijze voor het bepalen in een testmonster van componenten van de reactie tussen een specifiek bindend eiwit en de bijbehorende bindbare stof onder toepassing van ten minste een gemerkte component, werkwijze voor het bereiden van de gemerkte component, en testkit voor de bepaling van immunocomponenten. |
-
1990
- 1990-09-27 CA CA002026409A patent/CA2026409C/en not_active Expired - Lifetime
- 1990-09-28 DK DK90310671T patent/DK0426300T3/da active
- 1990-09-28 AT AT90310671T patent/ATE166975T1/de not_active IP Right Cessation
- 1990-09-28 GR GR900100722A patent/GR1000722B/el not_active IP Right Cessation
- 1990-09-28 ES ES90310671T patent/ES2117628T3/es not_active Expired - Lifetime
- 1990-09-28 EP EP90310671A patent/EP0426300B1/en not_active Expired - Lifetime
- 1990-09-28 DE DE69032363T patent/DE69032363T2/de not_active Expired - Lifetime
- 1990-09-29 JP JP2262922A patent/JPH03206959A/ja active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2347034A1 (es) * | 2009-04-21 | 2010-10-22 | Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina | Procedimiento para la obtencion de nanoparticulas metalicas. |
| WO2010122194A1 (es) * | 2009-04-21 | 2010-10-28 | Centro De Investigación Biomédica En Red En Bioingeniería, Biomateriales Y Nanomedicina | Procedimiento para la obtención de nanopartículas metálicas |
| ES2347034B1 (es) * | 2009-04-21 | 2011-09-08 | Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina | Procedimiento para la obtencion de nanoparticulas metalicas. |
Also Published As
| Publication number | Publication date |
|---|---|
| GR900100722A (en) | 1992-01-20 |
| CA2026409A1 (en) | 1991-03-30 |
| DK0426300T3 (da) | 1999-02-01 |
| DE69032363D1 (de) | 1998-07-09 |
| EP0426300B1 (en) | 1998-06-03 |
| ATE166975T1 (de) | 1998-06-15 |
| JPH03206959A (ja) | 1991-09-10 |
| DE69032363T2 (de) | 1998-10-22 |
| CA2026409C (en) | 2004-11-09 |
| GR1000722B (el) | 1992-11-23 |
| EP0426300A1 (en) | 1991-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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