ES2117628T3 - Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este. - Google Patents

Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este.

Info

Publication number
ES2117628T3
ES2117628T3 ES90310671T ES90310671T ES2117628T3 ES 2117628 T3 ES2117628 T3 ES 2117628T3 ES 90310671 T ES90310671 T ES 90310671T ES 90310671 T ES90310671 T ES 90310671T ES 2117628 T3 ES2117628 T3 ES 2117628T3
Authority
ES
Spain
Prior art keywords
hydroxylamine
reducing agent
reagent containing
narrow distribution
seed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90310671T
Other languages
English (en)
Inventor
Ernest G Schutt
Anh V Le
Michael J Cennerazzo
Robert E Nemore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Diagnostic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Diagnostic Systems Inc filed Critical Ortho Diagnostic Systems Inc
Application granted granted Critical
Publication of ES2117628T3 publication Critical patent/ES2117628T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0004—Preparation of sols
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0004—Preparation of sols
    • B01J13/0043—Preparation of sols containing elemental metal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Manufacture Of Metal Powder And Suspensions Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Colloid Chemistry (AREA)

Abstract

UN METODO PARA PRODUCIR UN REACTIVO QUE CONTENGA UNA DISTRIBUCION ESTRECHA DE PARTICULAS DE SOL METALICAS DE TAMAÑO SELECCIONADO PARA SER UTILIZADO COMO REACTIVOS DE INMUNOENSAYOS O COMO MARCADORES DE ETIQUETAS O CELULAS PARA TECNICAS MICROSCOPICAS. EL NUEVO PROCESO DE SOL METALICO DE SEMBRADO COLOIDAL DE LOS APLICANTES DE LA PATENTE INCLUYE: LA PREPARACION DE NUCLEOS DE ORO O SIMIENTE UTILIZANDO UN AGENTE REDUCTOR FUERTE EN PRESENCIA DE UN AGENTE ESTABILIZADOR SELECCIONADO DE MODO QUE NINGUNO DE LOS AGENTES AFECTARA DE MANERA APRECIABLE EL CRECIMIENTO SUBSIGUIENTE DE LA SIMIENTE PRODUCIDA; LA PREPARACION DE PARTICULAS DE SOL METALICAS DE DIFERENTES TAMAÑOS UTILIZANDO LA SIMIENTE PREPARADA SEGUN EL METODO DE LOS APLICANTES DE LA PATENTE Y DE HIDROXILAMINA O CITRATO SODICO COMO AGENTE REDUCTOR; INACTIVANDO LA HIDROXALAMINA Y SUS DERIVADOS DE REACCION CUANDO LA HIDROXILAMINA ES EL AGENTE REDUCTOR; RECUBRIMIENTO DE LAS PARTICULAS CON UN MATERIAL SELECCIONADO; Y UTILIZACION DE LECHE DESNATADA COMO POSTRECUBRIDOR.
ES90310671T 1989-09-29 1990-09-28 Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este. Expired - Lifetime ES2117628T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41518489A 1989-09-29 1989-09-29

Publications (1)

Publication Number Publication Date
ES2117628T3 true ES2117628T3 (es) 1998-08-16

Family

ID=23644702

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90310671T Expired - Lifetime ES2117628T3 (es) 1989-09-29 1990-09-28 Metodo de produccion de un reactivo que contiene una distribucion estrecha de particulas coloidales de tamaño seleccionado y utilizacion de este.

Country Status (8)

Country Link
EP (1) EP0426300B1 (es)
JP (1) JPH03206959A (es)
AT (1) ATE166975T1 (es)
CA (1) CA2026409C (es)
DE (1) DE69032363T2 (es)
DK (1) DK0426300T3 (es)
ES (1) ES2117628T3 (es)
GR (1) GR1000722B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2347034A1 (es) * 2009-04-21 2010-10-22 Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina Procedimiento para la obtencion de nanoparticulas metalicas.

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW239881B (es) * 1992-12-22 1995-02-01 Sienna Biotech Inc
US6200820B1 (en) 1992-12-22 2001-03-13 Sienna Biotech, Inc. Light scatter-based immunoassay
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
AU6016999A (en) * 1998-04-20 1999-12-13 University Of North Carolina At Chapel Hill, The Nanometer sized particles containing a reactive monolayer adsorbed thereon and methods of making the same
IL126776A (en) 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold
US7364920B2 (en) 1999-10-27 2008-04-29 Technion Research And Development Foundation Ltd. Method for gold deposition
AU1945901A (en) 1999-12-03 2001-06-12 Surromed, Inc. Hydroxylamine seeding of colloidal metal nanoparticles
CA2537199C (en) 2003-08-28 2011-11-29 Tama-Tlo, Ltd. Precious metal colloid, precious metal microparticle, composition, and process for producing the precious metal microparticle
WO2008103824A1 (en) * 2007-02-23 2008-08-28 Chinese Academy Of Inspection And Quarantine (Caiq) Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection
GB0724870D0 (en) * 2007-12-21 2008-01-30 Univ Lincoln The Preparation of metal colloids
JP5035622B2 (ja) * 2008-01-11 2012-09-26 積水化学工業株式会社 着色ラテックス
CN102539773B (zh) * 2011-12-31 2014-07-16 上海凯创生物技术有限公司 氯胺酮胶体金检测试剂盒及其制备方法
DE102013108664A1 (de) 2013-08-09 2015-02-12 Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh Oberflächenmodifizierte Metallkolloide und ihre Herstellung
EP2835402B1 (en) 2013-08-09 2020-07-08 Leibniz-Institut für Neue Materialien gemeinnützige GmbH Formation of surface modified metal colloids
EP3165923B1 (en) 2014-07-01 2020-02-05 NIPPON STEEL Chemical & Material Co., Ltd. Marker, immunoassay method, immunoassay reagent, method for assaying analyte, analyte measurement kit, and lateral- flow chromatographic test strip
WO2016002742A1 (ja) 2014-07-01 2016-01-07 新日鉄住金化学株式会社 樹脂-金属複合体、標識物質、免疫学的測定法、免疫学的測定用試薬、アナライトの測定方法、アナライト測定用キット、及び、ラテラルフロー型クロマト用テストストリップ
CN105067807B (zh) * 2015-04-30 2018-01-09 珠海丽珠试剂股份有限公司 一种免疫检测用纳米胶体金的制备方法
US11215611B2 (en) 2015-07-11 2022-01-04 Nippon Steel Chemical & Material Co., Ltd. Resin-platinum composite and usage thereof
CN105436516B (zh) * 2015-12-03 2018-06-08 南昌大学 可控粒径高吸光强度多枝状胶体金纳米粒子的制备方法
KR102640613B1 (ko) 2016-12-28 2024-02-26 닛테츠 케미컬 앤드 머티리얼 가부시키가이샤 금속-수지 복합체 및 그 이용
CN111229321A (zh) * 2020-01-16 2020-06-05 吉林大学 一种具有强催化功能的谷胱甘肽保护的铂金合金纳米簇、制备方法及其应用
CN112094699B (zh) * 2020-09-27 2023-03-28 广西壮族自治区林业科学研究院 一种樟树纯露的提取方法
CN115575623B (zh) * 2022-12-06 2023-03-28 深圳市卓润生物科技有限公司 胶体金及其制备方法和应用
CN116217991B (zh) * 2023-03-09 2024-02-27 四川大学 一种圆偏振发光薄膜制备方法和应用
CN116930482B (zh) * 2023-07-31 2025-05-09 山东康华生物医疗科技股份有限公司 一种胃幽门螺旋杆菌抗原检测试纸条用的胶体金制备方法及试纸条的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
JPS63307208A (ja) * 1987-06-08 1988-12-14 Chiyoda Chem Eng & Constr Co Ltd 貴金属微粉末の製造方法
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
NL8702769A (nl) * 1987-11-19 1989-06-16 Holland Biotechnology Werkwijze voor het bepalen in een testmonster van componenten van de reactie tussen een specifiek bindend eiwit en de bijbehorende bindbare stof onder toepassing van ten minste een gemerkte component, werkwijze voor het bereiden van de gemerkte component, en testkit voor de bepaling van immunocomponenten.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2347034A1 (es) * 2009-04-21 2010-10-22 Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina Procedimiento para la obtencion de nanoparticulas metalicas.
WO2010122194A1 (es) * 2009-04-21 2010-10-28 Centro De Investigación Biomédica En Red En Bioingeniería, Biomateriales Y Nanomedicina Procedimiento para la obtención de nanopartículas metálicas
ES2347034B1 (es) * 2009-04-21 2011-09-08 Centro De Investigacion Biomedica En Red En Bioingenieria. Biomateriales Y Nanomedicina Procedimiento para la obtencion de nanoparticulas metalicas.

Also Published As

Publication number Publication date
GR900100722A (en) 1992-01-20
CA2026409A1 (en) 1991-03-30
DK0426300T3 (da) 1999-02-01
DE69032363D1 (de) 1998-07-09
EP0426300B1 (en) 1998-06-03
ATE166975T1 (de) 1998-06-15
JPH03206959A (ja) 1991-09-10
DE69032363T2 (de) 1998-10-22
CA2026409C (en) 2004-11-09
GR1000722B (el) 1992-11-23
EP0426300A1 (en) 1991-05-08

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