ES2117640T3 - Composicion para mejorar la supervivencia de materiales biologicos. - Google Patents

Composicion para mejorar la supervivencia de materiales biologicos.

Info

Publication number
ES2117640T3
ES2117640T3 ES91904854T ES91904854T ES2117640T3 ES 2117640 T3 ES2117640 T3 ES 2117640T3 ES 91904854 T ES91904854 T ES 91904854T ES 91904854 T ES91904854 T ES 91904854T ES 2117640 T3 ES2117640 T3 ES 2117640T3
Authority
ES
Spain
Prior art keywords
alanine
antifreeze
invention describes
survival
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91904854T
Other languages
English (en)
Inventor
Boris Rubinsky
Arthur L Devries
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California, San Diego
Original Assignee
University of California Berkeley
University of California, San Diego
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California, San Diego filed Critical University of California Berkeley
Application granted granted Critical
Publication of ES2117640T3 publication Critical patent/ES2117640T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

EL PRESENTE INVENTO DESCRIBE COMPOSICIONES ACUOSAS DE SUBSTANCIAS, TALES COMO LAS MOLECULAS ORGANICAS, QUE SON UTILIES PARA PROTEGER Y PRESERVAR TEJIDOS Y MEMBRANAS DE CELULAS ANIMALES O VEGETALES EXPUESTOS A TEMPERATURAS HIPOTERMICAS E HIPERTERMICAS O CONDICIONES QUIMICAS NO FISIOLOGICAS Y PARA MODIFICAR EL PROCESO DE CONGELACION DE LOS LIQUIDOS EN TEJIDO O CELULAS ANIMALES O VEGETALES BIOLOGICOS. MAS ESPECIFICAMENTE, EL PRESENTE INVENTO DESCRIBE EL USO DE POLIPEPTIDO ANTICONGELANTE O GLICOPEPTIDO ANTICONGELANTE DERIVADO, POR EJEMPLO DEL FLUIDO O SUERO DE PECES ARTICOS Y ANTARTICOS. LOS COMPUESTOS ANTICONGELANTES IDONEOS ESTAN RELACIONADOS CON AQUELLOS POLIPEPTIDOS CON SEGMENTOS MULTIPLES ALANINA-ALANINA-TREONINA O ALANINA-ALANINA-ALANINA-.
ES91904854T 1990-01-17 1991-01-17 Composicion para mejorar la supervivencia de materiales biologicos. Expired - Lifetime ES2117640T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46605090A 1990-01-17 1990-01-17
US56246190A 1990-08-03 1990-08-03

Publications (1)

Publication Number Publication Date
ES2117640T3 true ES2117640T3 (es) 1998-08-16

Family

ID=27041515

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91904854T Expired - Lifetime ES2117640T3 (es) 1990-01-17 1991-01-17 Composicion para mejorar la supervivencia de materiales biologicos.

Country Status (9)

Country Link
EP (1) EP0511317B1 (es)
JP (1) JPH089521B2 (es)
AT (1) ATE165208T1 (es)
AU (1) AU659795B2 (es)
CA (1) CA2074162C (es)
DE (1) DE69129294T2 (es)
DK (1) DK0511317T3 (es)
ES (1) ES2117640T3 (es)
WO (2) WO1991010361A1 (es)

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US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
CN1085076C (zh) * 1995-01-05 2002-05-22 加利福尼亚大学董事会 脂质体和生物细胞在向温性相变过程中防止渗漏的方法
US5620732A (en) * 1995-06-07 1997-04-15 The Pillsbury Company Method of making ice cream
WO1997002343A1 (en) 1995-07-05 1997-01-23 Unilever Plc Expression of ocean fish antifreeze peptide in a food grade organism and its application in food products
JPH0928722A (ja) * 1995-07-19 1997-02-04 Kajiwara Hiroshi 長期保存可能な肝補助体及びその製造方法
EP0788745A1 (fr) * 1996-02-09 1997-08-13 Societe Des Produits Nestle S.A. Agents d'inhibition de la croissance des cristaux de la glace
GB2315662A (en) * 1996-07-26 1998-02-11 Unilever Plc Antifreeze peptides in frozen foods
ATE240659T1 (de) * 1996-07-26 2003-06-15 Unilever Nv Gefrorene nahrungsmittel mit peptid gefrierschutzmitteln
GB2315661B (en) 1996-07-26 2000-05-03 Unilever Plc Frozen food product
EP0924990B1 (en) * 1996-07-26 2006-06-28 Unilever N.V. Frozen food with antifreeze peptides
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
DE69929071T2 (de) * 1998-09-21 2006-08-17 21St Century Medicine Inc., Cucamonga Verbesserte kälteschutzlösungen
US20020042131A1 (en) * 2000-06-09 2002-04-11 Organ Recovery Systems Cryopreservation method using cryoprotective composition of propanediol and a vehicle solution
US8580487B2 (en) 2001-05-29 2013-11-12 Core Dynamics Limited Methods of preserving functionality of an organ, preserving fertility of a patient undergoing a treatment expected to cause sterility and assuring a supply of viable gametes for future use
DE10141681A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Anti-Freezing Proteinen und/oder Anti-freezing Glycoproteinen
AU2002330726A1 (en) * 2002-08-28 2004-03-19 I.M.T. Interface Multigrad Technology Ltd Methods of preserving the functionality of an organ.
WO2004022081A1 (de) * 2002-09-07 2004-03-18 Beiersdorf Ag Kosmetische oder dermatologische zubereitungen mit einem gehalt an anti-freezing proteinen und/oder anti-freezing glycoproteinen
US7169321B2 (en) * 2002-10-28 2007-01-30 Battelle Memorial Institute Biobased deicing/anti-icing fluids
US7105105B2 (en) 2002-10-28 2006-09-12 Battelle Memorial Institute Deicing/anti-icing fluids
SI2656854T1 (sl) * 2003-02-04 2015-09-30 Cornell Research Foundation, Inc. Uporabe aromatsko-kationskega peptida
JP2004284983A (ja) * 2003-03-20 2004-10-14 National Institute Of Advanced Industrial & Technology 含水物中における物質の凍結濃縮を抑制する方法、生理活性物質の失活を抑制する方法、および成分が均質に拡散した凍結物又は凍結乾燥物を製造する方法
EP1725680B1 (en) * 2004-02-04 2009-12-23 QIAGEN North American Holdings, Inc. Dutp based compositions for reducing primer-aggregate formation during nucleic acid amplification
WO2005095586A1 (ja) * 2004-03-31 2005-10-13 Shionogi & Co., Ltd. 不凍糖タンパク質誘導体を含有する細胞凍結保存用組成物
US7604929B2 (en) 2005-04-21 2009-10-20 In Vitro Technologies, Inc. Cellular compositions and methods for their preparation
CN101918437B (zh) * 2007-11-21 2013-08-14 罗斯基勒大学 具有冰结合活性的多肽
EP2536800B1 (en) 2010-02-17 2018-05-09 Battelle Memorial Institute Compositions for deicing/anti-icing
US9243176B2 (en) 2010-02-17 2016-01-26 Battelle Memorial Institute Compositions for deicing/anti-icing
US9080092B2 (en) 2010-02-17 2015-07-14 Battelle Memorial Institute Compositions for deicing/anti-icing
CN102640745B (zh) * 2012-05-04 2014-05-21 南京林业大学 一种胚性材料的超低温冷冻保存复苏方法
WO2015140178A1 (en) 2014-03-17 2015-09-24 Tfchem Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms
WO2017034940A1 (en) * 2015-08-21 2017-03-02 Skone Rene Benson Coverslip removal systems and methods
WO2018191371A1 (en) 2017-04-12 2018-10-18 X-Therma, Inc. Novel supercooling methods for preservation of biological samples
CN107333751A (zh) * 2017-07-25 2017-11-10 昆明医科大学第二附属医院 一种含抗冻蛋白的细胞冻存液
CN108396054A (zh) * 2018-03-30 2018-08-14 山东诺贝肽生物科技有限公司 一种酶解南极冰鱼制备低聚肽的方法
US20200087612A1 (en) * 2018-09-19 2020-03-19 Liang Chih Yang Device for deriving antarctic chionodraco rastrospinosus skin antifreeze protein
US12453345B2 (en) 2019-04-09 2025-10-28 Institute Of Chemistry, Chinese Academic Of Sciences Serum-free cryopreservation solution and preparation method and application thereof
EP3939427A4 (en) * 2019-04-09 2022-07-13 Peking University Third Hospital DMSO-FREE CRYOPRESERVATION SOLUTION, ITS PREPARATION PROCESS AND ITS APPLICATION
CN111789105B (zh) * 2019-04-09 2022-10-18 北京大学第三医院（北京大学第三临床医学院） 一种氨基酸类冷冻保存液在干细胞冻存中的应用
AU2020256873B2 (en) * 2019-04-09 2023-08-17 Institute Of Chemistry, Chinese Academy Of Sciences Thawing fluid, preparation method therefor and use thereof
SG11202110868XA (en) * 2019-04-09 2021-11-29 Institute Of Chemistry Chinese Academy Of Sciences Biomimetic ice-inhibiting material and cryopreservation solution comprising same
EP4090157B1 (en) 2020-01-13 2025-04-23 The Regents of The University of California Devices and methods for high-stability supercooling of aqueous media and biological matter
KR102454226B1 (ko) * 2020-12-04 2022-10-14 고려대학교 산학협력단 Dna 나노구조체를 포함하는 동결 보호용 조성물 및 그 이용방법
CN117426369B (zh) * 2023-10-12 2026-07-28 四川农业大学 一种卵母细胞冷冻保存的抗氧化添加剂及应用
WO2026110084A1 (en) * 2024-11-20 2026-05-28 Cryobio, Inc. Systems and methods for utilization of ice proteins

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JPS6061503A (ja) * 1983-09-14 1985-04-09 Hoxan Corp 臓器の保存方法
JPS60226588A (ja) * 1984-04-24 1985-11-11 Kanegafuchi Chem Ind Co Ltd 酵素修飾蛋白質系不凍剤
US4688387A (en) * 1985-11-12 1987-08-25 Vital Force, Inc. Method for preservation and storage of viable biological materials at cryogenic temperatures
US4980277A (en) * 1987-10-16 1990-12-25 Cultor Ltd. Cryoprotectant solution and method
FR2632820B1 (fr) * 1988-06-22 1990-11-16 Inst Kriobiologii Procede de conservation a basse temperature du sperme
US4965185A (en) * 1988-06-22 1990-10-23 Grischenko Valentin I Method for low-temperature preservation of embryos
US5001047A (en) * 1988-07-14 1991-03-19 Barnet L. Liberman Method of preserving organs
US4931361A (en) * 1988-11-18 1990-06-05 California Institute Of Technology Cryoprotective reagents in freeze-drying membranes
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US5131850A (en) * 1989-11-03 1992-07-21 Cryolife, Inc. Method for cryopreserving musculoskeletal tissues

Also Published As

Publication number Publication date
WO1992012722A1 (en) 1992-08-06
DK0511317T3 (da) 1999-01-25
AU7335491A (en) 1991-08-05
DE69129294T2 (de) 1998-10-01
EP0511317A1 (en) 1992-11-04
CA2074162C (en) 1999-05-11
JPH089521B2 (ja) 1996-01-31
WO1991010361A1 (en) 1991-07-25
DE69129294D1 (de) 1998-05-28
AU659795B2 (en) 1995-06-01
ATE165208T1 (de) 1998-05-15
JPH05503706A (ja) 1993-06-17
CA2074162A1 (en) 1991-07-18
EP0511317A4 (en) 1993-09-22
EP0511317B1 (en) 1998-04-22

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