ES2119535T3 - Procedimiento para procesar muestras organicas. - Google Patents
Procedimiento para procesar muestras organicas.Info
- Publication number
- ES2119535T3 ES2119535T3 ES96112571T ES96112571T ES2119535T3 ES 2119535 T3 ES2119535 T3 ES 2119535T3 ES 96112571 T ES96112571 T ES 96112571T ES 96112571 T ES96112571 T ES 96112571T ES 2119535 T3 ES2119535 T3 ES 2119535T3
- Authority
- ES
- Spain
- Prior art keywords
- sample
- procedure
- organic
- processing
- processing organic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000001493 electron microscopy Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000012744 immunostaining Methods 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 238000000386 microscopy Methods 0.000 abstract 1
- 238000010186 staining Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A LA ELABORACION DE TEJIDOS ORGANICOS, PARA PREPARARLOS PARA UNA POSTERIOR INVESTIGACION, COMO MICROSCOPIA OPTICA, MICROSCOPIA ELECTRONICA, TINCION PARA MICROONDAS, INMUNOTINCION, DESCALCIFICACION, HIBRIDACION, ETC. LA PRESENTE INVENCION DESCRIBE UN PROCEDIMIENTO DE ELABORACION DE TEJIDO ORGANICOS, QUE COMPRENDE LA FIJACION DE UNA MUESTRA ORGANICA, DESHIDRATACION Y PURIFICACION DE LA MUESTRA Y, POSTERIORMENTE, INFILTRACION Y EMBEBIMIENTO DE LA MUESTRA EN UN MEDIO DE SOPORTE, PARA PREPARARLA PARA POSTERIORES EXAMENES. LAS FASES DE DESHIDRATACION Y PURIFICACION SE LLEVAN A CABO SIMULTANEAMENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96112571A EP0822403B1 (en) | 1996-08-02 | 1996-08-02 | Process for processing organic specimens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2119535T3 true ES2119535T3 (es) | 1998-10-01 |
Family
ID=8223071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96112571T Expired - Lifetime ES2119535T3 (es) | 1996-08-02 | 1996-08-02 | Procedimiento para procesar muestras organicas. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6042874A (es) |
| EP (1) | EP0822403B1 (es) |
| JP (1) | JP3925664B2 (es) |
| AT (1) | ATE169112T1 (es) |
| AU (1) | AU4297597A (es) |
| DE (1) | DE69600484T2 (es) |
| ES (1) | ES2119535T3 (es) |
| WO (1) | WO1998005938A1 (es) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6793890B2 (en) | 1997-08-20 | 2004-09-21 | The University Of Miami | Rapid tissue processor |
| EP1005633B1 (en) * | 1997-08-20 | 2008-09-03 | The University Of Miami | A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method |
| DE60029129T2 (de) * | 1999-12-14 | 2006-11-09 | The University Of Miami, Miami | Schnelle gewebeaufbereitungsvorrichtung |
| JP3427268B2 (ja) * | 2001-06-04 | 2003-07-14 | 周 市原 | 立体的型枠を用いた生物組織標本作製法 |
| GB2377757B (en) * | 2001-07-19 | 2004-11-17 | Ann-Shyn Chiang | An aqueous tissue clearing solution |
| US6472216B1 (en) * | 2001-07-24 | 2002-10-29 | Ann-Shyn Chiang | Aqueous tissue clearing solution |
| CN100473990C (zh) | 2001-10-01 | 2009-04-01 | 徠卡生物体系墨尔本控股有限公司 | 组织处理器 |
| US6703242B1 (en) | 2002-01-02 | 2004-03-09 | Vladimir V. Senatorov | Dark-field microscopy visualization of unstained axonal pathways using oil of wintergreen |
| US7138226B2 (en) | 2002-05-10 | 2006-11-21 | The University Of Miami | Preservation of RNA and morphology in cells and tissues |
| US20040126837A1 (en) * | 2002-05-23 | 2004-07-01 | Matthew Baker | Pseudo-tissues and uses thereof |
| WO2003100384A1 (en) * | 2002-05-28 | 2003-12-04 | Diapath S.R.L. | Composition for the preparation of histological, autopsical, cytological samples |
| EP1367381A1 (en) * | 2002-05-28 | 2003-12-03 | Imberg S.r.l. | Composition for the preparation of histological, autopsical, cytological samples |
| US7541161B2 (en) * | 2002-10-31 | 2009-06-02 | University Of Massachusetts | Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins |
| US7618828B2 (en) | 2003-06-30 | 2009-11-17 | Academisch Ziekenhuis Groningen | Method for histoprocessing |
| EP1673608A4 (en) | 2003-09-29 | 2008-05-07 | Vision Biosystems Ltd | SYSTEM AND METHOD FOR PROCESSING HISTOLOGICAL TISSUE SPECIMENS |
| AU2004283291B2 (en) * | 2003-10-24 | 2010-08-12 | The University Of Miami | Simplified tissue processing |
| US8409871B2 (en) * | 2004-05-25 | 2013-04-02 | Leica Biosystems Melbourne Pty Ltd | Method of treatment of tissue processing fluid and apparatus therefor |
| DE602004018112D1 (de) | 2004-06-07 | 2009-01-15 | Milestone Srl | Verfahren und Vorrichtung zur mikrowellen-unterstützten automatischen Gewebebehandlung |
| US7273587B1 (en) | 2004-12-02 | 2007-09-25 | Collaborative Laboratory Services, Llc | Rapid tissue processing method and apparatus |
| US7273720B1 (en) | 2004-12-02 | 2007-09-25 | Collaborative Laboratory Services, Llc | Rapid tissue processing method and apparatus |
| US20060228772A1 (en) * | 2005-04-11 | 2006-10-12 | Donndelinger Thomas M | Compositions and methods for preparing specimens for microscopic analysis |
| US7769962B2 (en) * | 2005-12-12 | 2010-08-03 | Jeda Technologies, Inc. | System and method for thread creation and memory management in an object-oriented programming environment |
| WO2008028236A1 (en) * | 2006-09-05 | 2008-03-13 | Leica Biosystems Melbourne Pty Ltd | Composition and method for handling tissue samples |
| US7666620B2 (en) * | 2006-11-08 | 2010-02-23 | Richard-Allan Scientific Company | Rapid tissue processing system |
| US7906076B2 (en) * | 2007-07-02 | 2011-03-15 | University Of Massachusetts | Method and apparatus for biopsy sample processing |
| US8158381B2 (en) * | 2008-03-27 | 2012-04-17 | Richard-Allan Scientific Company | Methods for integrated tissue processing and staining |
| US20090298172A1 (en) * | 2008-05-28 | 2009-12-03 | Steven Paul Wheeler | Histological specimen treatment apparatus and method |
| DE102009025574A1 (de) * | 2009-06-19 | 2010-12-23 | Leica Biosystems Nussloch Gmbh | Verfahren zum automatischen Bearbeiten von Gewebeproben in einem Gewebeprozessor |
| EP2278295A1 (en) * | 2009-07-24 | 2011-01-26 | Milestone S.r.l. | Single cavity tissue histology tissue-processor |
| US20110045565A1 (en) * | 2009-08-18 | 2011-02-24 | Leica Biosystems Nussloch Gmbh | Apparatus and method for accelerated tissue infiltration by means of microwave excitation |
| US10126216B2 (en) | 2011-02-17 | 2018-11-13 | Ventana Medical Systems, Inc. | Method for tissue sample fixation |
| US10267769B2 (en) | 2010-03-04 | 2019-04-23 | Ventana Medical Systems, Inc. | Processing system for processing specimens using acoustic energy |
| US10539487B2 (en) | 2010-03-04 | 2020-01-21 | Ventana Medical Systems, Inc. | Systems and methods for monitoring tissue sample processing |
| US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
| WO2013115476A1 (ko) * | 2012-01-31 | 2013-08-08 | 국립암센터 | 검체 시료의 응집용 조성물, 이를 이용한 파라핀 블록의 제작방법 및 상기 파라핀 블록을 이용한 세포 마이크로어레이용 세포군집 표본의 제조방법 |
| US8563234B2 (en) | 2012-02-23 | 2013-10-22 | Anastasios J. Tousimis | Critical point drying systems and methods for in situ tissue preservation |
| ITCA20120004A1 (it) | 2012-03-30 | 2012-06-29 | Abdelkrim Harchi | Unico reattivo disidratante e diafanizzante per istologia e citologia non nocivo e non tossico, biodegradabile 88%, a bassa volatilita' |
| CN104583754A (zh) | 2012-06-22 | 2015-04-29 | 莱卡生物系统努斯洛赫有限责任公司 | 组织样本容器和方法 |
| WO2013192606A1 (en) | 2012-06-22 | 2013-12-27 | Leica Biosystems Nussloch Gmbh | Biopsy tissue sample transport device and method of using thereof |
| US9389154B2 (en) | 2013-03-15 | 2016-07-12 | Leica Biosystems Nussloch Gmbh | Tissue cassette with biasing element |
| CA2845830C (en) | 2013-03-15 | 2020-10-27 | Leica Biosystems Nussloch Gmbh | Tissue cassette with retractable member |
| US9052256B2 (en) | 2013-03-15 | 2015-06-09 | Leica Biosystems Nussloch Gmbh | Method for processing and embedding tissue |
| JP6134932B2 (ja) * | 2013-06-18 | 2017-05-31 | サクラ精機株式会社 | 組織片処理装置および組織片処理装置の動作方法 |
| EP2927664A1 (de) * | 2014-04-04 | 2015-10-07 | Aurel Popa | Vorrichtung zur gleichzeitigen Präparation einer Mehrzahl von Frischgewebeschnitten sowie ein Durchführungsverfahren |
| CN106211762B (zh) | 2014-04-04 | 2020-08-14 | 麻省理工学院 | 向带电基质中、在带电基质中和/或从带电基质中主动转运带电分子 |
| US10365189B2 (en) | 2015-05-07 | 2019-07-30 | Steven Wheeler | Histological specimen treatment |
| WO2018228508A1 (en) * | 2017-06-15 | 2018-12-20 | Sunstone Scientific Limited. | Paraffin shield coating for microscope slide |
| IT201700085124A1 (it) * | 2017-07-26 | 2019-01-26 | I R C C S Saverio De Bellis | Procedimento per la conservazione a lungo termine di pezzi anatomici di particolare interesse |
| WO2020194033A1 (en) * | 2019-03-27 | 2020-10-01 | Diapath S.P.A. | Method and apparatus for processing biological specimens |
| CN110771601B (zh) * | 2019-11-21 | 2022-02-18 | 钦州市中医药研究所 | 一种新鲜植物标本及其制备方法 |
| EP4164697A4 (en) * | 2020-06-15 | 2024-01-03 | Leica Biosystems Nussloch GmbH | FABRIC PROCESSOR AND FABRIC SAMPLE PROCESSING METHOD |
| IT202000025159A1 (it) | 2020-10-23 | 2022-04-23 | Diapath S P A | Composizione per il trattamento di campioni biologici, citologici, istologici e autoptici. |
| WO2022084907A1 (en) * | 2020-10-23 | 2022-04-28 | Diapath S.P.A. | Composition for the treatment of biological, cytological, histological and autopsical samples |
| JP7688706B2 (ja) * | 2020-12-01 | 2025-06-04 | パスロニクス コーポレイション | 可変電力冷マイクロ波組織処理装置 |
| IT202100027884A1 (it) * | 2021-10-29 | 2023-04-29 | Diapath S P A | Procedimento migliorato per la processazione di campioni biologici. |
| CN114088493B (zh) * | 2021-11-19 | 2023-06-16 | 四川大学华西医院 | 一种动物眼球病理切片制作方法 |
| IT202200014608A1 (it) | 2022-07-12 | 2024-01-12 | Diapath S P A | Composizione migliorata per il trattamento di campioni biologici, citologici, istologici e autoptici. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3889014A (en) * | 1972-02-22 | 1975-06-10 | Triangle Biomedical Equipment | Automatic electron microscopy tissue processor method |
| SE8501959L (sv) * | 1985-04-23 | 1986-10-24 | Henrik Gerhard Renvall | Framstellning av ett vevnadspreparat |
| US4839194A (en) * | 1985-07-05 | 1989-06-13 | Bone Diagnostic Center | Methods of preparing tissue samples |
| US4911915A (en) * | 1987-10-13 | 1990-03-27 | Richard-Allan Medical Industries | Method of processing tissue specimens and dehydrant solvent for use therein |
| DE3824936A1 (de) * | 1988-06-28 | 1990-03-22 | Schubert Werner | Schnellfixierung |
| CA1320539C (en) * | 1988-07-05 | 1993-07-20 | Kenneth W. Dudley | Method and apparatus for ultrafast microwave tissue fixation |
| US4891239A (en) * | 1988-07-05 | 1990-01-02 | Raytheon Company | Method and apparatus for ultrafast microwave tissue fixation |
| US5089288A (en) * | 1989-06-24 | 1992-02-18 | Berger Hermann J | Method for impregnating tissue samples in paraffin |
| WO1992019952A1 (en) * | 1991-05-07 | 1992-11-12 | Wescor, Inc. | Improved staining method for histology and cytology specimens |
| DE4400815A1 (de) * | 1994-01-13 | 1995-07-20 | Mls Gmbh | Verfahren und Vorrichtung zum Einbetten eines Gegenstandes, insbesondere eines Probematerials, in eine Einbettmasse |
| US5431952A (en) * | 1994-02-28 | 1995-07-11 | Board Of Trustees Operating Michigan State University | Method for preservation of biological tissue |
| WO1996018101A1 (en) * | 1994-12-09 | 1996-06-13 | Cellular Dimorphism Institute | Histologic method of tissue analysis |
-
1996
- 1996-08-02 ES ES96112571T patent/ES2119535T3/es not_active Expired - Lifetime
- 1996-08-02 DE DE69600484T patent/DE69600484T2/de not_active Expired - Fee Related
- 1996-08-02 EP EP96112571A patent/EP0822403B1/en not_active Expired - Lifetime
- 1996-08-02 AT AT96112571T patent/ATE169112T1/de not_active IP Right Cessation
-
1997
- 1997-08-01 US US09/051,031 patent/US6042874A/en not_active Expired - Fee Related
- 1997-08-01 JP JP50760298A patent/JP3925664B2/ja not_active Expired - Lifetime
- 1997-08-01 AU AU42975/97A patent/AU4297597A/en not_active Abandoned
- 1997-08-01 WO PCT/EP1997/004207 patent/WO1998005938A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69600484D1 (de) | 1998-09-03 |
| AU4297597A (en) | 1998-02-25 |
| EP0822403A1 (en) | 1998-02-04 |
| EP0822403B1 (en) | 1998-07-29 |
| DE69600484T2 (de) | 1999-04-01 |
| ATE169112T1 (de) | 1998-08-15 |
| WO1998005938A1 (en) | 1998-02-12 |
| US6042874A (en) | 2000-03-28 |
| JPH11513123A (ja) | 1999-11-09 |
| JP3925664B2 (ja) | 2007-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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