ES2119682A1 - Una composicion framaceutica que contiene delapril y manidiopino para el tratamiento de enfermedades cardiovasculares y renales. - Google Patents

Una composicion framaceutica que contiene delapril y manidiopino para el tratamiento de enfermedades cardiovasculares y renales.

Info

Publication number
ES2119682A1
ES2119682A1 ES09601015A ES9601015A ES2119682A1 ES 2119682 A1 ES2119682 A1 ES 2119682A1 ES 09601015 A ES09601015 A ES 09601015A ES 9601015 A ES9601015 A ES 9601015A ES 2119682 A1 ES2119682 A1 ES 2119682A1
Authority
ES
Spain
Prior art keywords
manidipine
delapril
compsn
renal diseases
contg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09601015A
Other languages
English (en)
Other versions
ES2119682B1 (es
Inventor
Yoshiyuki Inada
Paolo Chiesi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Takeda Pharmaceutical Co Ltd
Original Assignee
Chiesi Farmaceutici SpA
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA, Takeda Chemical Industries Ltd filed Critical Chiesi Farmaceutici SpA
Publication of ES2119682A1 publication Critical patent/ES2119682A1/es
Application granted granted Critical
Publication of ES2119682B1 publication Critical patent/ES2119682B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UNA COMPOSICION FARMACEUTICA QUE CONTIENE DELAPRIL Y MANIDIPINO PARA ENFERMEDADES CARDIOVASCULARES Y RENALES. UNA COMBINACION DE FARMACOS A BASE DE DELAPRIL O UNA DE SUS SALES COMO MANIDIPINO O UNA DE SUS SALES INTENSIFICA LOS EFECTOS DE CADA UNO POR SI SOLO, Y UNA MENOR DOSIS DE CADA FARMACO EN LA COMBINACION PUEDE RESULTAR SUFICIENTE PARA UTILIZARSE A FIN DE PREVENIR Y TRATAR ENFERMEDADES CARDIOVASCULARES Y RENALES. ADEMAS, LA INCIDENCIA DE EFECTOS DESFAVORABLES EN UNA ALTA DOSIS DE CADA FARMACO A SOLAS SE PUEDE REDUCIR EN LA COMBINACION DE ESTOS FARMACOS.
ES09601015A 1995-05-09 1996-05-07 Una composicion farmaceutica que contiene delapril y manidipino para el tratamiento de enfermedades cardiovasculares y renales. Expired - Fee Related ES2119682B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95830186 1995-05-09

Publications (2)

Publication Number Publication Date
ES2119682A1 true ES2119682A1 (es) 1998-10-01
ES2119682B1 ES2119682B1 (es) 1999-07-01

Family

ID=8221919

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09601015A Expired - Fee Related ES2119682B1 (es) 1995-05-09 1996-05-07 Una composicion farmaceutica que contiene delapril y manidipino para el tratamiento de enfermedades cardiovasculares y renales.

Country Status (4)

Country Link
BR (1) BR1101039A (es)
ES (1) ES2119682B1 (es)
FR (1) FR2733911B1 (es)
IT (1) IT1285093B1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107323A (en) 1996-04-05 2000-08-22 Takeda Chemical Industries, Ltd. Pharmaceutical composition
IT1398168B1 (it) * 2010-02-16 2013-02-14 Chiesi Farma Spa Uso di ingredienti attivi in combinazione per il trattamento delle complicanze del diabete.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0259838A2 (en) * 1986-09-09 1988-03-16 Syntex (U.S.A.) Inc. Pharmaceutical composition containing A 1,4-dihydropyridine derivative and an acylated 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
DE4308504A1 (de) * 1993-03-18 1994-09-22 Knoll Ag Neue Verwendung einer Kombination aus Verapamil und Trandolapril

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569789B2 (en) * 1984-05-03 1988-02-18 Brigham And Women's Hospital A.c.e. inhibitors to treat renal diseases
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
NL8702502A (nl) * 1986-11-03 1988-06-01 Sandoz Ag Farmaceutisch preparaat voor toepassing tegen hypertensie en congestieve cardiale insufficientie.
TW197945B (es) * 1990-11-27 1993-01-11 Hoechst Ag
IT1254314B (it) * 1992-03-27 1995-09-14 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
JPH06172220A (ja) * 1992-12-03 1994-06-21 Upjohn Co:The 虚血性疾患治療用医薬組成物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0259838A2 (en) * 1986-09-09 1988-03-16 Syntex (U.S.A.) Inc. Pharmaceutical composition containing A 1,4-dihydropyridine derivative and an acylated 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
DE4308504A1 (de) * 1993-03-18 1994-09-22 Knoll Ag Neue Verwendung einer Kombination aus Verapamil und Trandolapril

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KISO TO RINSHO. The Clinical Report, 1993, Vol. 27, N‘ 5, pßginas 1627-1646 * Todo el documento * *
MESSERLI, F.H. Combination therapy in hypertension. J. Human Hypertension, 1992, Vol. 6 (Supl. 2), pßginas S19-S21 * Todo el documento * *
SATO, KEIICHIRO et al. Thirteen-week oral toxicity study of manidipine hydrochloride ((CV-4093 (2HCl)) and delapril hydrochloride (CV-3317) by concurrent administration in rats. YAKURI TO CHIRYO, 1990, Vol. 18, pßginas 3283-99 * Todo el documento * *
SCALBERT, E. et al. Systemic and regional hemodynamic Interactions of perindopril and nitrendipine in the spontaneously hypertensive rat. J. Cardiovascular Pharmacol. 1990, Vol. 15, n‘ 4, pßginas 676-683 * Todo el documento * *
ZANCHETTI, A. Nitrendipine and ACE Inhibitors. J. Cardiovascular Pharmacol. 1988, Vol. 12, (Supl. 4), pßginas S80-S85 * Todo el documento * *

Also Published As

Publication number Publication date
FR2733911B1 (fr) 1998-05-29
BR1101039A (pt) 2002-04-02
ITTO960379A0 (it) 1996-05-08
FR2733911A1 (fr) 1996-11-15
IT1285093B1 (it) 1998-06-03
ITTO960379A1 (it) 1997-11-08
ES2119682B1 (es) 1999-07-01

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