ES2119992T3 - Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt). - Google Patents

Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt).

Info

Publication number
ES2119992T3
ES2119992T3 ES94900935T ES94900935T ES2119992T3 ES 2119992 T3 ES2119992 T3 ES 2119992T3 ES 94900935 T ES94900935 T ES 94900935T ES 94900935 T ES94900935 T ES 94900935T ES 2119992 T3 ES2119992 T3 ES 2119992T3
Authority
ES
Spain
Prior art keywords
pct
mgmt
hybridoma ecacc
nov
date jun
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900935T
Other languages
English (en)
Inventor
Benjamin Fuk Loi Li
Teck Choon Ayi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Molecular and Cell Biology
Original Assignee
Institute of Molecular and Cell Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Molecular and Cell Biology filed Critical Institute of Molecular and Cell Biology
Application granted granted Critical
Publication of ES2119992T3 publication Critical patent/ES2119992T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL PRESENTE INVENTO PROPORCIONA ANTICUERPOS CAPACES DE DISCRIMINAR ENTRE MGMT HUMANO Y UNA FORMA ALQUILATADA DE LUGAR ACTIVO DE ESTA ENZIMA EN UN PROCEDIMIENTO DE INMUNOPRECIPITACION. LOS ANTICUERPOS MONOCLONALES CON ESTA CAPACIDAD DE DISCRIMINACION SE OBTIENEN DE HIBRIDOMA ECACC 92112510 E HIBRIDOMA ECACC 93112514, QUE FUERON DEPOSITADOS EN LA COLECCION EUROPEA DE CULTIVOS DE CELULAS ANIMALES, REINO UNIDO BAJO EL TRATADO DE BUDAPEST EN 25 DE NOVIEMBRE DE 1992 Y 25 DE NOVIEMBRE DE 1993, RESPECTIVAMENTE. EL ANTICUERPO MONOCLONAL DE HIBRIDOMA ECACC 92112510 SE HA DENOMINADO MAB 5H7. EL ANTICUERPO MONOCLONAL DE HIBRIDOMA ECACC 93112514 SE HA LLAMADO MAB 3C7.
ES94900935T 1992-11-27 1993-11-29 Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt). Expired - Lifetime ES2119992T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929224888A GB9224888D0 (en) 1992-11-27 1992-11-27 Monoclonal antibody

Publications (1)

Publication Number Publication Date
ES2119992T3 true ES2119992T3 (es) 1998-10-16

Family

ID=10725777

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900935T Expired - Lifetime ES2119992T3 (es) 1992-11-27 1993-11-29 Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt).

Country Status (10)

Country Link
US (1) US5817514A (es)
EP (1) EP0670908B1 (es)
AT (1) ATE169680T1 (es)
AU (1) AU688289B2 (es)
CA (1) CA2149867A1 (es)
DE (1) DE69320364T2 (es)
ES (1) ES2119992T3 (es)
GB (1) GB9224888D0 (es)
SG (1) SG48841A1 (es)
WO (1) WO1994012660A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407804A (en) * 1992-05-22 1995-04-18 Applied Genetics Inc. Assays for O6 -methylguanine-DNA methyltransferase
US6773897B2 (en) * 2000-09-29 2004-08-10 The Johns Hopkins University School Of Medicine Method of predicting the clinical response to chemotherapeutic treatment with alkylating agents
DE60212642T2 (de) * 2001-04-10 2007-06-14 ECOLE POLYTECHNIQUE FéDéRALE DE LAUSANNE Verfahren zur verwendung von o6-alkylguanin-dna-alkyltransferasen
BRPI0706540A2 (pt) 2006-01-18 2011-03-29 Merck Patent Gmbh terapia especìfica usando ligantes de integrina para tratar cáncer
EP2441464B1 (en) 2007-01-18 2014-04-09 Merck Patent GmbH Integrin ligands for use in treating colon cancer
CA2686848A1 (en) 2007-05-08 2008-11-20 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
TR201820051T4 (tr) * 2008-06-19 2019-01-21 Prothix Bv Anti-faktör XI Antikorlarının Trombüs Oluşumunun Engellenmesi Veya Tedavisi İçin Kullanılması
CN102448497A (zh) 2009-05-25 2012-05-09 默克专利有限公司 在癌症治疗中的西仑吉肽的持续给药
CN103153328A (zh) 2010-07-16 2013-06-12 默克专利股份有限公司 肽在乳腺癌和/或骨转移灶的治疗中的用途
CN103974978B (zh) * 2011-11-25 2017-03-08 弗劳恩霍夫应用研究促进协会 用于检测snap/clip标记物的单克隆抗体
BR112014013745B1 (pt) 2011-12-09 2022-06-14 Institut Pasteur Método de teste in vitro, kit de detecção e seu uso, método in vitro de diagnóstico, método de fabricação de kit, e teste de imunosseleção multiplex

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407804A (en) * 1992-05-22 1995-04-18 Applied Genetics Inc. Assays for O6 -methylguanine-DNA methyltransferase

Also Published As

Publication number Publication date
GB9224888D0 (en) 1993-01-13
AU688289B2 (en) 1998-03-12
CA2149867A1 (en) 1994-06-09
WO1994012660A1 (en) 1994-06-09
DE69320364D1 (de) 1998-09-17
EP0670908A1 (en) 1995-09-13
AU5570594A (en) 1994-06-22
EP0670908B1 (en) 1998-08-12
US5817514A (en) 1998-10-06
DE69320364T2 (de) 1998-12-10
SG48841A1 (en) 1998-05-18
ATE169680T1 (de) 1998-08-15

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