ES2119992T3 - Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt). - Google Patents

Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt).

Info

Publication number
ES2119992T3
ES2119992T3 ES94900935T ES94900935T ES2119992T3 ES 2119992 T3 ES2119992 T3 ES 2119992T3 ES 94900935 T ES94900935 T ES 94900935T ES 94900935 T ES94900935 T ES 94900935T ES 2119992 T3 ES2119992 T3 ES 2119992T3
Authority
ES
Spain
Prior art keywords
pct
mgmt
hybridoma ecacc
nov
date jun
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900935T
Other languages
English (en)
Inventor
Benjamin Fuk Loi Li
Teck Choon Ayi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Molecular and Cell Biology
Original Assignee
Institute of Molecular and Cell Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Molecular and Cell Biology filed Critical Institute of Molecular and Cell Biology
Application granted granted Critical
Publication of ES2119992T3 publication Critical patent/ES2119992T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL PRESENTE INVENTO PROPORCIONA ANTICUERPOS CAPACES DE DISCRIMINAR ENTRE MGMT HUMANO Y UNA FORMA ALQUILATADA DE LUGAR ACTIVO DE ESTA ENZIMA EN UN PROCEDIMIENTO DE INMUNOPRECIPITACION. LOS ANTICUERPOS MONOCLONALES CON ESTA CAPACIDAD DE DISCRIMINACION SE OBTIENEN DE HIBRIDOMA ECACC 92112510 E HIBRIDOMA ECACC 93112514, QUE FUERON DEPOSITADOS EN LA COLECCION EUROPEA DE CULTIVOS DE CELULAS ANIMALES, REINO UNIDO BAJO EL TRATADO DE BUDAPEST EN 25 DE NOVIEMBRE DE 1992 Y 25 DE NOVIEMBRE DE 1993, RESPECTIVAMENTE. EL ANTICUERPO MONOCLONAL DE HIBRIDOMA ECACC 92112510 SE HA DENOMINADO MAB 5H7. EL ANTICUERPO MONOCLONAL DE HIBRIDOMA ECACC 93112514 SE HA LLAMADO MAB 3C7.
ES94900935T 1992-11-27 1993-11-29 Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt). Expired - Lifetime ES2119992T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929224888A GB9224888D0 (en) 1992-11-27 1992-11-27 Monoclonal antibody

Publications (1)

Publication Number Publication Date
ES2119992T3 true ES2119992T3 (es) 1998-10-16

Family

ID=10725777

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900935T Expired - Lifetime ES2119992T3 (es) 1992-11-27 1993-11-29 Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt).

Country Status (10)

Country Link
US (1) US5817514A (es)
EP (1) EP0670908B1 (es)
AT (1) ATE169680T1 (es)
AU (1) AU688289B2 (es)
CA (1) CA2149867A1 (es)
DE (1) DE69320364T2 (es)
ES (1) ES2119992T3 (es)
GB (1) GB9224888D0 (es)
SG (1) SG48841A1 (es)
WO (1) WO1994012660A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407804A (en) * 1992-05-22 1995-04-18 Applied Genetics Inc. Assays for O6 -methylguanine-DNA methyltransferase
JP2004509643A (ja) * 2000-09-29 2004-04-02 ザ　ジョンズ　ホプキンス　ユニバーシティー　スクール　オブ　メディシン アルキル化剤を用いた化学療法による治療に対する臨床反応を予測する方法
NZ537939A (en) * 2001-04-10 2005-08-26 Ecole Polytech Methods using O6-alkylguanine-DNA alkyltransferases for labelling a protein of interest which is fused to the AGT
EP1973569B1 (en) 2006-01-18 2013-05-22 Merck Patent GmbH Specific therapy using integrin ligands for treating cancer
JP2010516645A (ja) 2007-01-18 2010-05-20 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌を治療するためのインテグリンリガンドを用いる特異的療法および薬剤
EP2409700A1 (en) 2007-05-08 2012-01-25 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
US20110159006A1 (en) * 2008-06-19 2011-06-30 Erik Hack Use of anti-factor xi antibodies for prevention of thrombus formation
US20120130146A1 (en) 2009-05-25 2012-05-24 Merck Patent Gmbh Continuous administration of cilengitide in cancer treatments
MX2013000521A (es) 2010-07-16 2013-03-05 Merck Patent Gmbh Partido para usarse en tratamiento de cancer de mama y/o metastasis osea.
WO2013076304A1 (en) * 2011-11-25 2013-05-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Monoclonal antibody for the detection of snap/clip tag
ES2648899T3 (es) 2011-12-09 2018-01-08 Institut Pasteur Inmunoensayo de cribado múltiplex

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407804A (en) * 1992-05-22 1995-04-18 Applied Genetics Inc. Assays for O6 -methylguanine-DNA methyltransferase

Also Published As

Publication number Publication date
GB9224888D0 (en) 1993-01-13
DE69320364T2 (de) 1998-12-10
EP0670908B1 (en) 1998-08-12
SG48841A1 (en) 1998-05-18
AU5570594A (en) 1994-06-22
US5817514A (en) 1998-10-06
EP0670908A1 (en) 1995-09-13
ATE169680T1 (de) 1998-08-15
CA2149867A1 (en) 1994-06-09
WO1994012660A1 (en) 1994-06-09
DE69320364D1 (de) 1998-09-17
AU688289B2 (en) 1998-03-12

Similar Documents

Publication Publication Date Title
TR200002405T2 (tr) İnsan CD40' a karşı antikorlar
DE69429095D1 (de) Humanisierte antikoerper
FR12C0004I2 (fr) Anticorps contre l'antigene ctla-4 humain et utilisation
DE69840383D1 (de) Ctl epitope des epstein-barr virus
ES2119992T3 (es) Anticuerpos especificos de 6-o-metilguanina-adn-metiltransferasa (mgmt).
AR248044A1 (es) Una secuencia de adn que codifica anticuerpos monoclonales humanizados contra interleuquinas humanas, metodo de obtencion y de seleccion de dichos anticuerpos, vector recombinante y celula huesped.
DE69709632D1 (de) Humanisierte monoklonale anti-cd40 antikörper und fragmente zur hemmung der b-zellaktivierung
ATE316137T1 (de) Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor
DK0626447T3 (da) Monoklonale antistoffer og Fv, som er specifikke for CD2-antigen
AU3045497A (en) Human monoclonal antibody against hepatitis b virus surface antigen (hbvsag)
DE69128273D1 (de) Für toxin b von clostridium difficile spezifische monoklonale antikörper
Thomas et al. Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous‐cell carcinoma
DE69322783D1 (de) Monoklonale Antikörper gegen Glykoprotein P
GR3029483T3 (en) Antibodies against t-cells as therapeutics
ATE206621T1 (de) Il-8 antagonisten zur behandlung von asthma
NO972522L (no) Monoklonale antistoffer med immunoundertrykkende aktivitet
DE59812529D1 (de) Monoklonaler Antikörper 4G8B4B12 gegen humanes FLT3/FLK2
ATE40216T1 (de) Monoklonaler antikoerper.
DE69533504D1 (de) Monoklonale antikörper gegen antigene, die durch hämatopoietische helferzellen exprimiert werden
GB2284608A (en) 06-Methylguanine-DNA-methyltransferase (mgmt) specific antibodies
Leanderson et al. Effects of μ‐specific antibodies on B cell growth and maturation
ATE293685T1 (de) Monoklonaler antikörper gegen ratte beta-2- integrin alpha d untereinheit und entsprechendes hybridoma
ATE251643T1 (de) Antikörper 67d2 gegen cd164
RU98104739A (ru) Штамм культивируемых клеток мышиной гибридомы, используемый для получения моноклональных антител к ядрышковому антигену, ассоциированному с клеточной пролиферацией
NO172549C (no) Monoklonalt humanurokinase-antistoff, immunoabsorberende middel for rensing av humanurokinase samt anvendelse av antistoffet for detektering av humanurokinase

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 670908

Country of ref document: ES