ES2120990T3 - Celda electrolitica y procedimiento para el marcado de proteinas y peptidos. - Google Patents

Celda electrolitica y procedimiento para el marcado de proteinas y peptidos.

Info

Publication number
ES2120990T3
ES2120990T3 ES92304395T ES92304395T ES2120990T3 ES 2120990 T3 ES2120990 T3 ES 2120990T3 ES 92304395 T ES92304395 T ES 92304395T ES 92304395 T ES92304395 T ES 92304395T ES 2120990 T3 ES2120990 T3 ES 2120990T3
Authority
ES
Spain
Prior art keywords
electrode
operating
cell
marking
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92304395T
Other languages
English (en)
Inventor
Carey Lee Scortichini
Janeth M Bartlett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of ES2120990T3 publication Critical patent/ES2120990T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
    • C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Metallurgy (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

SE MUESTRA UN CELDA ELECTROLITICA PARA MARCAR PROTEINAS, PEPTIDOS Y OTRAS MOLECULAS ORGANICAS QUE EMPLEA UNA MITAD DE CELDA CATODICA Y UNA MITAD DE CELDA ANODICA DONDE UN ELECTRODO POROSO SE LOCALIZA EN UNA MITAD DE CELDA Y UN ELECTRODO OPERATIVO SE LOCALIZA EN LA OTRA MITAD DE CELDA, ESTANDO AMBAS CELDAS DIVIDIDAS POR UN SEPARADOR. UN ELECTRODO DE REFERENCIA SE LOCALIZA EN LA MITAD DE CELDA QUE CONTIENE EL ELECTRODO OPERATIVO, Y SITUADO FUERA DE LA TRAYECTORIA DE CORRIENTE ENTRE EL ELECTRODO OPERATIVO Y EL ELECTRODO CONTADOR CONFIERE UN CONTROL PRECISO DEL POTENCIAL DEL ELECTRODO OPERATIVO, LO QUE PERMITE QUE SE ALCANCE EL MAXIMO NIVEL DE MARCACION A LA VEZ QUE SE MINIMIZA EL DAÑO OXIDATIVO A LAS MOLECULAS ORGANICAS, PEPTIDOS O PROTEINAS. LA SATURACION DEL ELECTRODO OPERATIVO CON MARCACION NO RADIOACTIVA ACOPLADA CON UNA RELACION ENTRE EL AREA DE SUPERFICIE DEL ELECTRODO OPERATIVO Y EL VOLUMEN DE LA MITAD DE CELDA QUE CONTIENE EL ELECTRODO OPERATIVO DE ENTRE 0,0001 A 10 CM-1 MINIMIZA EL PROBLEMA DE PERDIDA DE ACTIVIDAD DE MARCACION DE RADIO DEBIDA A LA ABSORCION EN EL ELECTRODO OPERATIVO.
ES92304395T 1991-05-15 1992-05-15 Celda electrolitica y procedimiento para el marcado de proteinas y peptidos. Expired - Lifetime ES2120990T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/701,438 US5230783A (en) 1991-05-15 1991-05-15 Electrolytic cell and process for the labeling of proteins and peptides

Publications (1)

Publication Number Publication Date
ES2120990T3 true ES2120990T3 (es) 1998-11-16

Family

ID=24817377

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92304395T Expired - Lifetime ES2120990T3 (es) 1991-05-15 1992-05-15 Celda electrolitica y procedimiento para el marcado de proteinas y peptidos.

Country Status (23)

Country Link
US (2) US5230783A (es)
EP (1) EP0514187B1 (es)
JP (1) JP2612145B2 (es)
KR (1) KR0164876B1 (es)
CN (1) CN1036866C (es)
AT (1) ATE171483T1 (es)
AU (1) AU650337B2 (es)
CA (1) CA2068804C (es)
DE (1) DE69227065T2 (es)
DK (1) DK0514187T3 (es)
ES (1) ES2120990T3 (es)
FI (1) FI108371B (es)
HU (1) HU216300B (es)
IE (1) IE921540A1 (es)
IL (1) IL101893A (es)
MX (1) MX9202260A (es)
NO (1) NO309497B1 (es)
SA (1) SA92130072B1 (es)
SG (1) SG45300A1 (es)
TW (1) TW225560B (es)
UA (1) UA27771C2 (es)
WO (1) WO1992021019A1 (es)
ZA (1) ZA923559B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5590264A (en) * 1991-04-10 1996-12-31 International Business Machines Corporation Method and apparatus for graphic association of user dialog displays with primary applications in a data processing system
GB9226840D0 (en) * 1992-12-23 1993-02-17 Unilever Plc Improvements in or relating to electrochemical reactions
US6482309B1 (en) 1999-10-20 2002-11-19 Oxibio, Inc. Electrolytic generation of nascent iodine as a method of treatment and for the prevention of infections associated with medical implant devices
CN109055968B (zh) * 2018-07-12 2020-07-24 芜湖职业技术学院 有机电合成电解装置
JP7166531B2 (ja) * 2018-12-21 2022-11-08 国立大学法人東京工業大学 電気化学的手法を用いたハロゲン化物の製造方法
DE102020122324A1 (de) 2020-08-26 2022-03-03 Gottfried Wilhelm Leibniz Universität Hannover, Körperschaft des öffentlichen Rechts Elektrolysezelle, Elektrolysetestsystem und Teststand zum Testen von dichtungsfreien Elektrolysezellen und/oder Elektrolysetestsystemen
EP4491612A4 (en) * 2022-03-08 2026-03-11 Univ Osaka PROCESS FOR PRODUCING A RADIOLABELLED ARYL COMPOUND BY ELECTROLYTIC OXIDATION REACTION

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US341490A (en) * 1886-05-11 billings
DE1187308B (de) * 1961-10-25 1965-02-18 Licentia Gmbh Anordnung zur Entregung von Synchronmaschinen
US3441490A (en) * 1964-11-13 1969-04-29 Jungner Instrument Ab Coulometric titration apparatus
US3784453A (en) * 1970-12-16 1974-01-08 H Dworkin Process and apparatus for making radioactive labeled protein material
BE795902A (fr) * 1972-02-25 1973-08-23 Rhone Poulenc Sa Procede de preparation du diiodo-3,5 hydroxy-4benzonitrile et de l'iodo-3 hydroxy-4 nitro-5benzonitrile
SU535271A1 (ru) * 1974-10-22 1976-11-15 Предприятие П/Я В-8046 Способ получени иодбензола
SU517222A1 (ru) * 1974-10-25 1977-06-25 Институт Биофизики Министерства Здравохранения Ссср Способ получени препарата бенгальска роза, меченного радиоизотопами йода
SU597744A2 (ru) * 1976-01-09 1978-03-15 Химико-Металлургический Институт Академии Наук Казахской Сср Электрод с активным слоем
SU601925A1 (ru) * 1976-04-19 1979-07-15 Институт биофизики АН СССР Способ получени пептидов, меченных изотопами йода
US4126034A (en) * 1978-01-30 1978-11-21 Rheem Manufacturing Company Method and apparatus for container pressure testing
HU179001B (en) * 1978-05-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 5-halo-6,9alpha-oxido-prostaglandin derivatives
US4184937A (en) * 1978-12-26 1980-01-22 Catalyst Research Corporation Electrochemical cell for the detection of chlorine
GB2081307A (en) * 1980-07-08 1982-02-17 Engelhard Min & Chem Use of electrocatalytic anodes in photolysis
US4464236A (en) * 1982-05-10 1984-08-07 The Dow Chemical Company Selective electrochemical oxidation of organic compounds
DE3234665A1 (de) * 1982-09-18 1984-03-22 Hoechst Ag Verfahren zur markierung von organselektiven substanzen aus blutbestandteilen mit technetium-99m
DE3313655C2 (de) * 1983-03-02 1995-03-23 Euro Celtique Sa Pharmazeutisches Jodophor-Präparat
EP0135638B1 (fr) * 1983-06-16 1986-11-12 Rhone-Poulenc Sante Procédé électrochimique de préparation de sulfoxydes de dérivés de thioformamides utiles comme médicaments
AU569918B2 (en) * 1983-10-13 1988-02-25 Ici Australia Operations Proprietary Limited Redox potential or ph electrode
US4859305A (en) * 1984-08-30 1989-08-22 Mine Safety Appliances Company Electrochemical cell
JPS61257490A (ja) * 1985-05-09 1986-11-14 Asahi Chem Ind Co Ltd 芳香族ジアミンの製造方法
US4666570A (en) * 1984-10-30 1987-05-19 Asahi Kasei Kogyo Kabushiki Kaisha Process for producing aromatic compound with functional groups
JPS61106786A (ja) * 1984-10-30 1986-05-24 Asahi Chem Ind Co Ltd ｐ−ヨ−ドアニリンの製造方法
US4644237A (en) * 1985-10-17 1987-02-17 International Business Machines Corp. Collision avoidance system
JPH01257490A (ja) * 1988-04-08 1989-10-13 Shiro Nagai コバルトフリーコリノイドの製造法
GB8817421D0 (en) * 1988-07-21 1988-08-24 Medisense Inc Bioelectrochemical electrodes

Also Published As

Publication number Publication date
FI935023A7 (fi) 1993-11-12
CA2068804A1 (en) 1992-11-16
HU9302925D0 (en) 1993-12-28
NO933704L (no) 1993-11-12
US5230783A (en) 1993-07-27
CA2068804C (en) 2002-07-16
EP0514187A1 (en) 1992-11-19
IL101893A0 (en) 1992-12-30
JPH06508206A (ja) 1994-09-14
FI935023A0 (fi) 1993-11-12
FI108371B (fi) 2002-01-15
IL101893A (en) 1994-11-28
WO1992021019A1 (en) 1992-11-26
SG45300A1 (en) 1998-01-16
SA92130072B1 (ar) 2004-05-24
HUT67029A (en) 1995-01-30
IE921540A1 (en) 1992-11-18
MX9202260A (es) 1993-08-01
HK1016021A1 (en) 1999-10-22
CN1036866C (zh) 1997-12-31
DK0514187T3 (da) 1999-06-14
JP2612145B2 (ja) 1997-05-21
NO933704D0 (no) 1993-10-14
AU650337B2 (en) 1994-06-16
US5246561A (en) 1993-09-21
AU1633592A (en) 1992-11-19
UA27771C2 (uk) 2000-10-16
HU216300B (hu) 1999-06-28
CN1069339A (zh) 1993-02-24
TW225560B (es) 1994-06-21
DE69227065D1 (de) 1998-10-29
NO309497B1 (no) 2001-02-05
ZA923559B (en) 1993-11-15
KR0164876B1 (ko) 1999-03-30
ATE171483T1 (de) 1998-10-15
DE69227065T2 (de) 1999-02-11
EP0514187B1 (en) 1998-09-23

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