ES2121016T3 - Reactivos y procedimientos que permiten realizar analisis de fijacion con captura de iones en dos etapas. - Google Patents

Reactivos y procedimientos que permiten realizar analisis de fijacion con captura de iones en dos etapas.

Info

Publication number
ES2121016T3
ES2121016T3 ES92914861T ES92914861T ES2121016T3 ES 2121016 T3 ES2121016 T3 ES 2121016T3 ES 92914861 T ES92914861 T ES 92914861T ES 92914861 T ES92914861 T ES 92914861T ES 2121016 T3 ES2121016 T3 ES 2121016T3
Authority
ES
Spain
Prior art keywords
capture reagent
solid phase
substance
analyte
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92914861T
Other languages
English (en)
Inventor
Janina Adamczyk
Daniel S Berry
Rosario Fico
Yi-Her Jou
Stephen D Stroupe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2121016T3 publication Critical patent/ES2121016T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

ESTA INVENCION PRESENTA NUEVOS METODOS DE ENSAYO QUE EMPLEAN UN REACTIVO DE CAPTURA, INCLUYENDO UN PRIMER MIEMBRO DE LIGAZON TIPICAMENTE CONJUGADO A UNA SUSTANCIA ANIONICA POLIMERA Y UN MATERIAL DE FASE SOLIDA QUE CONTIENE UNA POSICION DE REACCION, QUE COMPRENDE UNA SUSTANCIA CATIONICA POLIMERA QUE TIENE UN CONTENIDO DE NITROGENO DE AL MENOS ALREDEDOR DEL DOS POR CIENTO. EN UNA INCORPORACION UNA MUESTRA PARA PRUEBAS SOSPECHOSA DE CONTENER EL ANALITICO DE INTERES SE PUEDE PONER EN CONTACTO CON EL REACTIVO DE CAPTURA PARA FORMAR UN COMPLEJO DE CAPTURA REACTIVO/ANALITICO CARGADO. EL COMPLEJO SE PONE ENTONCES EN CONTACTO CON LA FASE SOLIDA CARGADA OPUESTAMENTE PARA ATRAER, FIJAR, E INMOBILIZAR AL COMPLEJO DE CAPTURA REACTIVO/ANALITICO. EL USO DE UNA SUSTANCIA POLICATIONICA, QUE TIENE UN CONTENIDO DE NITROGENO DE AL MENOS DOS POR CIENTO (EXCLUIDOS LOS IONES OPUESTOS), PARA PREPARAR UNA FASE SOLIDA CARGADA ADECUADAMENTE PROVEE UNA FASE SOLIDA QUE PUEDE SER SOMETIDA A UNA MAYOR EXTENSION DE MANIPULACION, TAL COMO LAVADOS MULTIPLES, SIN REDUCIR LA CAPACIDAD PARA ATRAER Y RETENER AL REACTIVO DE CAPTURA.
ES92914861T 1991-05-30 1992-04-10 Reactivos y procedimientos que permiten realizar analisis de fijacion con captura de iones en dos etapas. Expired - Lifetime ES2121016T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70747891A 1991-05-30 1991-05-30

Publications (1)

Publication Number Publication Date
ES2121016T3 true ES2121016T3 (es) 1998-11-16

Family

ID=24841859

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92914861T Expired - Lifetime ES2121016T3 (es) 1991-05-30 1992-04-10 Reactivos y procedimientos que permiten realizar analisis de fijacion con captura de iones en dos etapas.

Country Status (7)

Country Link
EP (1) EP0586605B1 (es)
JP (1) JPH06508211A (es)
AT (1) ATE169340T1 (es)
CA (1) CA2109925C (es)
DE (1) DE69226526T2 (es)
ES (1) ES2121016T3 (es)
WO (1) WO1992021770A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
AU1997895A (en) * 1994-03-15 1995-10-03 Abbott Laboratories Ion-capture reagents and methods for performing binding assays
US5707799A (en) * 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
EP3925533B1 (en) 2009-04-30 2024-04-10 DexCom, Inc. Performance reports associated with continuous sensor data from multiple analysis time periods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4121975A (en) * 1976-08-20 1978-10-24 Syva Company Pretreatment of samples for polyiodothyronine assays
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
JPS60500548A (ja) * 1982-12-03 1985-04-18 イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− 発色性支持体免疫測定法
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
US4935147A (en) * 1985-12-20 1990-06-19 Syntex (U.S.A.) Inc. Particle separation method
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices
US5051356A (en) * 1988-06-13 1991-09-24 Eastman Kodak Company Specific binding composition comprising a low pI protein or carbohydrate and a diagnostic test kit and method of use
US5094962A (en) * 1988-06-13 1992-03-10 Eastman Kodak Company Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit
JPH0750110B2 (ja) * 1988-12-22 1995-05-31 積水化学工業株式会社 免疫測定法
CA1341592C (en) * 1989-07-07 2009-04-14 Abbott Laboratories Ion capture reagents and methods for performing binding assays

Also Published As

Publication number Publication date
EP0586605A1 (en) 1994-03-16
CA2109925C (en) 2004-11-09
ATE169340T1 (de) 1998-08-15
JPH06508211A (ja) 1994-09-14
CA2109925A1 (en) 1992-12-10
WO1992021770A1 (en) 1992-12-10
EP0586605A4 (en) 1996-01-17
EP0586605B1 (en) 1998-08-05
DE69226526T2 (de) 1999-03-18
DE69226526D1 (de) 1998-09-10

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