ES2170100T3 - Procedimiento y sistema analitico mejorados para la realizacion de ensayos de fibrinogeno con precision, rapidez y sencillez. - Google Patents

Procedimiento y sistema analitico mejorados para la realizacion de ensayos de fibrinogeno con precision, rapidez y sencillez.

Info

Publication number
ES2170100T3
ES2170100T3 ES94918100T ES94918100T ES2170100T3 ES 2170100 T3 ES2170100 T3 ES 2170100T3 ES 94918100 T ES94918100 T ES 94918100T ES 94918100 T ES94918100 T ES 94918100T ES 2170100 T3 ES2170100 T3 ES 2170100T3
Authority
ES
Spain
Prior art keywords
rapidity
simplicity
precision
procedure
performance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94918100T
Other languages
English (en)
Inventor
Bruce J Oberhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiovascular Diagnostics Inc
Original Assignee
Cardiovascular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiovascular Diagnostics Inc filed Critical Cardiovascular Diagnostics Inc
Application granted granted Critical
Publication of ES2170100T3 publication Critical patent/ES2170100T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

SE PRESENTA UN METODO PARA LLEVAR A CABO UN ENSAYO CUANTITATIVO DE FIBRINOGENOS QUE HACE USO DE UNA QUIMICA DE REACTIVOS SECOS EN COMBINACION CON UN CAMPO MAGNETICO ROTATIVO Y QUE TIENE UNA CORRELACION EXCELENTE CON EL FIBROMETRO, EL ESTANDAR DE ORO EN LA INDUSTRIA. ADICIONALMENTE, SE PRESENTAN UN APARATO PARA LLEVAR A CABO EL ENSAYO, UN ENSAYO CUANTITATIVO DE FIBRINOGENOS Y UN METODO PARA LA PREPARACION DE UNA CURVA DE CALIBRACION A UTILIZAR CON EL ENSAYO CUANTITATIVO DE FIBRINOGENOS.
ES94918100T 1993-05-28 1994-05-27 Procedimiento y sistema analitico mejorados para la realizacion de ensayos de fibrinogeno con precision, rapidez y sencillez. Expired - Lifetime ES2170100T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/068,855 US5670329A (en) 1993-05-28 1993-05-28 Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field

Publications (1)

Publication Number Publication Date
ES2170100T3 true ES2170100T3 (es) 2002-08-01

Family

ID=22085142

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94918100T Expired - Lifetime ES2170100T3 (es) 1993-05-28 1994-05-27 Procedimiento y sistema analitico mejorados para la realizacion de ensayos de fibrinogeno con precision, rapidez y sencillez.

Country Status (11)

Country Link
US (1) US5670329A (es)
EP (1) EP0700448B1 (es)
JP (1) JP3497862B2 (es)
KR (1) KR100351602B1 (es)
AT (1) ATE212674T1 (es)
CA (1) CA2163858C (es)
DE (1) DE69429770T2 (es)
ES (1) ES2170100T3 (es)
IL (1) IL109817A (es)
TW (1) TW326075B (es)
WO (1) WO1994028168A1 (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6429017B1 (en) * 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US6898532B1 (en) 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6321164B1 (en) * 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
EP1712921A2 (en) * 1997-09-29 2006-10-18 F.Hoffmann-La Roche Ag Apparatus for separating magnetic particles
DE69839294T2 (de) 1997-09-29 2009-04-09 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
SE9800590D0 (sv) 1998-02-26 1998-02-26 Global Hemostasis Inst Mgr Ab Determination of polymerization/coagulation in a fluid
US6165795A (en) * 1998-06-25 2000-12-26 Cardiovascular Diagnostics, Inc. Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles
US6562299B1 (en) * 1998-09-18 2003-05-13 Cytyc Corporation Method and apparatus for preparing cytological specimens
US20030059347A1 (en) 1998-09-18 2003-03-27 Roy A. Ostgaard Sample vial for use in preparing cytological specimen
US6572824B1 (en) * 1998-09-18 2003-06-03 Cytyc Corporation Method and apparatus for preparing cytological specimens
ATE282208T1 (de) * 1999-02-04 2004-11-15 Bio Merieux Inc Verfahren und vorrichtung zum vorhersagen von haemostatischer funktionsstörung in patientenproben
NZ513390A (en) 1999-03-19 2003-01-31 Genencor Int Multi-through hole testing plate for high throughput screening
US6417004B1 (en) * 1999-04-29 2002-07-09 Helena Laboratories Corporation Enhancing clot detection in activated clotting time and other fibrin endpoint based tests
US6586259B1 (en) * 1999-11-15 2003-07-01 Pharmanetics Incorporated Platelet/leukocyte interaction assay and reagent therefor
US20020151040A1 (en) 2000-02-18 2002-10-17 Matthew O' Keefe Apparatus and methods for parallel processing of microvolume liquid reactions
JP3581306B2 (ja) * 2000-03-31 2004-10-27 株式会社イソワ インキ粘度測定装置並びにインキ粘度調整方法及びその装置
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
WO2002001081A2 (en) * 2000-06-23 2002-01-03 Micronics, Inc. Valve for use in microfluidic structures
US6902904B2 (en) * 2001-08-27 2005-06-07 Pharmanetics Incorporated Coagulation assay reagents containing lanthanides
US6680177B2 (en) * 2001-12-07 2004-01-20 Cardiovascular Diagnostics, Inc. Low molecular weight heparin assay, system and reagent therefor
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
US20060094108A1 (en) * 2002-12-20 2006-05-04 Karl Yoder Thermal cycler for microfluidic array assays
WO2004074818A2 (en) * 2002-12-20 2004-09-02 Biotrove, Inc. Assay apparatus and method using microfluidic arrays
CA2559171A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US8512219B2 (en) 2004-04-19 2013-08-20 The Invention Science Fund I, Llc Bioelectromagnetic interface system
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
DE102005028018A1 (de) * 2005-06-16 2006-12-21 Dade Behring Marburg Gmbh Verfahren zur Standardisierung von Gerinnungstesten
MX2009000544A (es) * 2006-07-17 2009-05-28 Universal Biosensors Pty Ltd Deteccion electroquimica de movilidad de particulas magneticas.
CN101983338B (zh) * 2008-03-31 2015-03-04 希森美康株式会社 凝血分析仪、凝血分析方法及计算机程序
JP5312835B2 (ja) * 2008-03-31 2013-10-09 シスメックス株式会社 血液凝固分析装置、血液凝固分析方法、及びコンピュータプログラム
JP5312834B2 (ja) * 2008-03-31 2013-10-09 シスメックス株式会社 血液凝固分析装置、血液凝固分析方法、及び、コンピュータプログラム
JP2011069718A (ja) * 2009-09-25 2011-04-07 Sekisui Medical Co Ltd 血液凝固反応における血液凝固時間延長剤
CN107389932B (zh) * 2010-09-15 2019-11-22 德比奥法姆国际股份有限公司 用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法
TWI499779B (zh) 2013-07-04 2015-09-11 Ind Tech Res Inst 檢測晶片及其使用方法
CN107003328A (zh) * 2014-12-18 2017-08-01 皇家飞利浦有限公司 用于确定生物样本中纤维蛋白原浓度的方法
KR102252259B1 (ko) * 2015-12-31 2021-05-14 주식회사 필로시스 혈액 응고 측정장치
JP6799245B2 (ja) * 2016-02-25 2020-12-16 国立研究開発法人産業技術総合研究所 血液のフィブリン量変化の計測方法
JP7191613B2 (ja) * 2018-09-26 2022-12-19 キヤノンメディカルシステムズ株式会社 血液凝固分析装置
JP7359538B2 (ja) * 2018-12-07 2023-10-11 株式会社エイアンドティー フィブリノゲン測定試薬
WO2020116556A1 (ja) * 2018-12-07 2020-06-11 株式会社エイアンドティー フィブリノゲン測定試薬
JP7410652B2 (ja) * 2019-04-12 2024-01-10 株式会社エイアンドティー フィブリノゲンの定量方法
GB201911527D0 (en) * 2019-08-12 2019-09-25 Univ Dublin City Method for the determination of plasma fibrinogen concentration in whole blood samples
CN111307915B (zh) * 2020-02-24 2022-04-12 河南工业大学 一种检测血液中纤维蛋白原浓度的检测装置及检测方法
JP7529446B2 (ja) * 2020-06-05 2024-08-06 株式会社エイアンドティー フィブリノゲン測定方法
CN113736624A (zh) * 2021-09-13 2021-12-03 上海知楚实业有限公司 一种新型单电机驱动的涂均摇床

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792113A (fr) * 1971-12-13 1973-05-30 Technicon Instr Melangeur de liquides contenant des particules magnetiques
US3861197A (en) * 1973-06-29 1975-01-21 Technicon Instr Method and apparatus for determining the viscosity of a liquid sample
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
US5156974A (en) * 1988-05-27 1992-10-20 Biodata Corporation Method for determining the fibrinogen level of a blood sample
US5120834A (en) * 1988-06-13 1992-06-09 American Biogenetic Sciences, Inc. Fibrin-specific monoclonal antibody
TW221493B (es) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
EP0587398B1 (en) * 1992-09-09 1998-01-14 Tokuyama Corporation Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof

Also Published As

Publication number Publication date
EP0700448A4 (en) 1998-10-07
DE69429770D1 (de) 2002-03-14
EP0700448A1 (en) 1996-03-13
IL109817A (en) 1998-02-08
DE69429770T2 (de) 2002-09-19
CA2163858C (en) 2004-07-13
EP0700448B1 (en) 2002-01-30
JP3497862B2 (ja) 2004-02-16
TW326075B (en) 1998-02-01
IL109817A0 (en) 1994-08-26
CA2163858A1 (en) 1994-12-08
WO1994028168A1 (en) 1994-12-08
ATE212674T1 (de) 2002-02-15
JPH08510908A (ja) 1996-11-19
US5670329A (en) 1997-09-23
KR100351602B1 (ko) 2002-12-31
KR960702528A (ko) 1996-04-27

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