ES2121808T3 - Microorganismos para la estabilizacion de plasmidos. - Google Patents

Microorganismos para la estabilizacion de plasmidos.

Info

Publication number
ES2121808T3
ES2121808T3 ES92119635T ES92119635T ES2121808T3 ES 2121808 T3 ES2121808 T3 ES 2121808T3 ES 92119635 T ES92119635 T ES 92119635T ES 92119635 T ES92119635 T ES 92119635T ES 2121808 T3 ES2121808 T3 ES 2121808T3
Authority
ES
Spain
Prior art keywords
plasmids
utilisation
microorganisms
stabilization
betaine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92119635T
Other languages
English (en)
Inventor
Thomas Dr Zimmerman
Cristiana Boraschi
Knut Burgdorf
Catherine Caubere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2121808T3 publication Critical patent/ES2121808T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/41—Rhizobium

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE DESCRIBEN NUEVOS MICROORGANISMOS CON PLASMIDAS ESTABLES, EN RELACION AL APROVECHAMIENTO DE LA BETAINA. ESTOS NUEVOS MICROORGANISMOS CONTIENEN A) UNA PLASMIDA HIBRIDA CON UN FRAGMENTO DE DNA, QUE CONTIENE UNA SECUENCIA GENETICA, QUE SE CODIFICA PARA EL APROVECHAMIENTO DE LAS BETAINAS, Y B) UNA MUTACION EN EL GEN CROMOSOMAL, CODIFICADO PARA EL APROVECHAMIENTO DE LA BETAINA.
ES92119635T 1991-11-21 1992-11-17 Microorganismos para la estabilizacion de plasmidos. Expired - Lifetime ES2121808T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH341291 1991-11-21

Publications (1)

Publication Number Publication Date
ES2121808T3 true ES2121808T3 (es) 1998-12-16

Family

ID=4255432

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92119635T Expired - Lifetime ES2121808T3 (es) 1991-11-21 1992-11-17 Microorganismos para la estabilizacion de plasmidos.

Country Status (14)

Country Link
US (2) US5891710A (es)
EP (1) EP0543344B1 (es)
JP (1) JP3399993B2 (es)
AT (1) ATE170563T1 (es)
CA (1) CA2083407C (es)
CZ (1) CZ281078B6 (es)
DE (1) DE59209482D1 (es)
DK (1) DK0543344T3 (es)
ES (1) ES2121808T3 (es)
HU (1) HU218739B (es)
IL (1) IL103811A (es)
MX (1) MX9206630A (es)
RU (1) RU2099418C1 (es)
SK (1) SK279052B6 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698879B1 (fr) * 1992-12-09 1995-01-13 Rhone Poulenc Biochimie gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes.
RU2133773C1 (ru) * 1993-10-08 1999-07-27 Лонца Аг Гены бутиробетаин/кротонобетаин-l-карнитин-метаболизма и их применение для микробиологического получения l-карнитина
ATE356214T1 (de) * 2001-01-31 2007-03-15 Lonza Ag Mikrobiologisches verfahren zur herstellung von l-carnitin
US7229792B2 (en) * 2004-05-03 2007-06-12 Vinod Pandiripally Method of producing recombinant proteins
WO2011121301A1 (en) * 2010-03-31 2011-10-06 Stabilitech Ltd Excipients for stabilising viral particles, polypeptides or biological material
ES2757591T3 (es) 2010-03-31 2020-04-29 Stabilitech Biopharma Ltd Estabilización de partículas virales
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55156591A (en) * 1979-05-23 1980-12-05 Ajinomoto Co Inc Method for stabilizing property of bacteria containing plasmid
US4650761A (en) * 1981-11-27 1987-03-17 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cell
EP0178764A1 (en) * 1984-08-28 1986-04-23 Genex Corporation Method of stabilizing a host microorganism/expression vector system for large scale production of proteins
DK594084A (da) * 1984-12-12 1986-06-13 Novo Industri As Fremgangsmaade til stabilisering af extra-chromosomale elementer i bakterier under dyrkning
US5198343A (en) * 1986-08-05 1993-03-30 Transgene, S.A. Method for expressing a heterologous protein in a dapD- mutant of E. coli and the strain obtained
CZ279464B6 (cs) * 1990-09-24 1995-05-17 Lonza A.G. Způsob hydroxylace methylových skupin v aromatických heterocyklech, hybridní plasmidy pL05 a p L04 uložené v mikroorganismech Pseudomonas putida a Escherichia coli

Also Published As

Publication number Publication date
CZ345092A3 (en) 1993-07-14
JP3399993B2 (ja) 2003-04-28
SK279052B6 (sk) 1998-06-03
EP0543344B1 (de) 1998-09-02
HUT63651A (en) 1993-09-28
CA2083407A1 (en) 1993-05-22
HU218739B (hu) 2000-11-28
SK345092A3 (en) 1995-11-08
IL103811A0 (en) 1993-04-04
MX9206630A (es) 1993-07-01
IL103811A (en) 2004-05-12
DK0543344T3 (da) 1998-11-09
HU9203644D0 (en) 1993-01-28
RU2099418C1 (ru) 1997-12-20
US5891710A (en) 1999-04-06
US6057146A (en) 2000-05-02
JPH06153926A (ja) 1994-06-03
EP0543344A1 (de) 1993-05-26
CA2083407C (en) 2002-07-30
ATE170563T1 (de) 1998-09-15
DE59209482D1 (de) 1998-10-08
CZ281078B6 (cs) 1996-06-12

Similar Documents

Publication Publication Date Title
ATE466948T1 (de) Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
ES2121808T3 (es) Microorganismos para la estabilizacion de plasmidos.
CA2153068A1 (en) Enhancer sequence for modulating expression in epithelial cells
DE69738586D1 (de) Hohe expressionsrate von proteinen
GR81947B (es)
ATE196164T1 (de) Gereinigte scytalidium lacassen und nukleinsäuren dafür kodierend
DE69535125D1 (de) Impstoff gegen felines immunodefizienz-virus
ATE42114T1 (de) Mikrobiologisch hergestelltes interferon alpha2(arg), dna-sequenz, die fuer dieses interferon codiert, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung.
DK224185D0 (da) Vektor til inkorporering i gaercellers chromosomer
ATE45767T1 (de) Dns molekuele enthaltend die gene fuer preprochymosin und dessen reifungsformen und dadurch transformierte mikroorganismen.
GR851866B (es)
ES2079348T3 (es) Procedimiento de estabilizacion de un plasmido contenido en una cepa bacteriana y cepa obtenida.
GB9215232D0 (en) Vaccines
CA2131719A1 (en) Nucleic acid sequences coding for or complementary to nucleic acid sequences coding for interleukin 9 receptor
EP0533153A3 (en) Pichia pastoris linear plasmids and dna fragments thereof
CO4790114A1 (es) Plasmidos bacterianos
DE69231145D1 (de) Für eine Esterase kodierendes Gen und dieses Gen enthaltender Mikroorganismus
AU1705097A (en) Bacterial donor cell useful in conjugation
ES8802075A1 (es) Procedimiento para la multiplicacion de un adn heterologo
ATE63759T1 (de) Streptomycinsensitives gen mit einer vielzahl von klonierungsstellen, dieses gen enthaltender plasmidvektor und diesen vektor enthaltender mikroorganismus.
SU1380209A1 (ru) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ
FR2696191B1 (fr) Acide nucléique codant pour une alpha-acétolactate décarboxylase et ses applications.
ATE96171T1 (de) Fuer flagellin kodierende dns und dieses enthaltender vektor.
ATE45759T1 (de) Latente primaere aminogruppen enthaltende, wasserverduennbare bindemittel fuer kationische elektrotauchlacke und verfahren zu ihrer herstellung.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 543344

Country of ref document: ES