ES2122324T3 - Procedimiento, reactivo y equipo para la deteccion de sangre oculta en las heces. - Google Patents
Procedimiento, reactivo y equipo para la deteccion de sangre oculta en las heces.Info
- Publication number
- ES2122324T3 ES2122324T3 ES94927402T ES94927402T ES2122324T3 ES 2122324 T3 ES2122324 T3 ES 2122324T3 ES 94927402 T ES94927402 T ES 94927402T ES 94927402 T ES94927402 T ES 94927402T ES 2122324 T3 ES2122324 T3 ES 2122324T3
- Authority
- ES
- Spain
- Prior art keywords
- fecal sample
- peroxide
- faeces
- reagent
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 210000003608 fece Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 230000002550 fecal effect Effects 0.000 abstract 3
- 102000001554 Hemoglobins Human genes 0.000 abstract 2
- 108010054147 Hemoglobins Proteins 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 150000002978 peroxides Chemical class 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/725—Haemoglobin using peroxidative activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/904—Oxidation - reduction indicators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SE PUEDE ANALIZAR UNA MUESTRA FECAL PARA DETECTAR LA PRESENCIA DE SANGRE OCULTA MEDIANTE LA COMBINACION DE LA MUESTRA FECAL CON: (A) UN SUSTRATO OXIDABLE QUE FORME UN PRODUCTO COLOREADO EN PRESENCIA DE PEROXIDO Y HEMOGLOBINA; (B) PEROXIDO DE HIDROGENO O UNA FUENTE DE PEROXIDO; Y (C) UN INTENSIFICADOR SELECCIONADO PARA AUMENTAR LA SENSIBILIDAD DEL ENSAYO. LOS INTENSIFICADORES ADECUADOS SON COMPUESTOS HETEROCICLICOS AROMATICOS QUE CONTIENEN NITROGENO MONOCICLICO; COMPUESTOS DE AMONIO TERCIARIO O CUATERNARIO QUE TIENEN UN FENILO, ALQUILO DE HIDROXI O ALQUILO DE HIDROXI ESTERIFICADO ACOPLADO AL NITROGENO; O QUINOLINA O UN DERIVADO SUSTITUIDO DE LA MISMA. SI HAY HEMOGLOBINA EN LA MUESTRA FECAL, EL SUSTRATO OXIDABLE SE CONVIERTE EN EL PRODUCTO COLOREADO, VISIBLEMENTE DETECTABLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/121,072 US5447868A (en) | 1993-09-14 | 1993-09-14 | Method, reagent and kit for the detection of fecal occult blood |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2122324T3 true ES2122324T3 (es) | 1998-12-16 |
Family
ID=22394332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94927402T Expired - Lifetime ES2122324T3 (es) | 1993-09-14 | 1994-09-13 | Procedimiento, reactivo y equipo para la deteccion de sangre oculta en las heces. |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US5447868A (es) |
| EP (1) | EP0720746B1 (es) |
| AU (1) | AU7686094A (es) |
| CA (1) | CA2171872C (es) |
| DE (1) | DE69411928T2 (es) |
| DK (1) | DK0720746T3 (es) |
| ES (1) | ES2122324T3 (es) |
| WO (1) | WO1995008120A1 (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10361802B1 (en) | 1999-02-01 | 2019-07-23 | Blanding Hovenweep, Llc | Adaptive pattern recognition based control system and method |
| US5447868A (en) * | 1993-09-14 | 1995-09-05 | Propper Manufacturing Co. Inc. | Method, reagent and kit for the detection of fecal occult blood |
| US7268700B1 (en) | 1998-01-27 | 2007-09-11 | Hoffberg Steven M | Mobile communication device |
| EP1350103B1 (en) * | 2000-01-19 | 2010-01-06 | Given Imaging Ltd. | A system for detecting substances |
| IL142026A (en) * | 2000-03-14 | 2008-04-13 | Yissum Res Dev Co | IN VITRO DEVELOPMENT FACILITY AND METHOD |
| AU2002234234A1 (en) * | 2001-01-12 | 2002-07-24 | Helena Laboratories Corporation | Occult blood test enhancer |
| US6811549B2 (en) | 2001-02-16 | 2004-11-02 | William H. Fleming | Administration of therapeutic or diagnostic agents using interlabial pad |
| US7684840B2 (en) * | 2002-08-13 | 2010-03-23 | Given Imaging, Ltd. | System and method for in-vivo sampling and analysis |
| US7223604B1 (en) | 2002-09-27 | 2007-05-29 | Science & Technology Corporation @ Unm | Methods and kits for the detection of erythrocytes |
| US9818136B1 (en) | 2003-02-05 | 2017-11-14 | Steven M. Hoffberg | System and method for determining contingent relevance |
| CN2718561Y (zh) * | 2003-07-11 | 2005-08-17 | 艾康生物技术(杭州)有限公司 | 用于取样签的保护套 |
| US7604589B2 (en) * | 2003-10-01 | 2009-10-20 | Given Imaging, Ltd. | Device, system and method for determining orientation of in-vivo devices |
| US20080241940A1 (en) * | 2004-07-22 | 2008-10-02 | Lastella Vincent P | Fecal sampling device and method |
| US8679420B2 (en) * | 2004-07-22 | 2014-03-25 | Immunostics, Inc. | Fecal sampling device and method |
| US7427505B2 (en) * | 2004-07-22 | 2008-09-23 | Immunostics, Inc. | Fecal occult blood testing device and method |
| EP2058661A1 (en) * | 2004-07-22 | 2009-05-13 | Immunostics, Inc. | Fecal occult blood testing device and method |
| US7687244B1 (en) * | 2004-11-17 | 2010-03-30 | John Fischer | Chromogenic composition for detecting spilled blood and associated methods |
| WO2007113839A2 (en) * | 2006-04-03 | 2007-10-11 | Given Imaging Ltd. | Device, system and method for in-vivo analysis |
| US8738106B2 (en) * | 2005-01-31 | 2014-05-27 | Given Imaging, Ltd | Device, system and method for in vivo analysis |
| IL174531A0 (en) * | 2005-04-06 | 2006-08-20 | Given Imaging Ltd | System and method for performing capsule endoscopy diagnosis in remote sites |
| US20090117660A1 (en) * | 2005-04-30 | 2009-05-07 | Oakville Hong Kong Co., Limited | Devices and methods for sample collection and analysis |
| US8062901B2 (en) | 2005-04-30 | 2011-11-22 | Alere Switzerland Gmbh | Devices and methods for sample collection and analysis |
| US7288413B2 (en) * | 2005-08-12 | 2007-10-30 | Beckman Coulter, Inc. | Combined chemical and immunochemical fecal occult blood test |
| US7577283B2 (en) * | 2005-09-30 | 2009-08-18 | Given Imaging Ltd. | System and method for detecting content in-vivo |
| US7567692B2 (en) * | 2005-09-30 | 2009-07-28 | Given Imaging Ltd. | System and method for detecting content in-vivo |
| US20070092401A1 (en) * | 2005-10-26 | 2007-04-26 | Feier Liao | Devices and methods for sample collection and analysis |
| CA2679725C (en) * | 2007-02-28 | 2015-07-07 | Quantrx Biomedical Corporation | Folded perineal pad |
| US8053203B2 (en) * | 2007-10-30 | 2011-11-08 | John Wan | Methods and device for the detection of occult blood |
| US8304596B2 (en) | 2008-04-11 | 2012-11-06 | Immunostics, Inc. | Fecal sampling device and method |
| US8515507B2 (en) * | 2008-06-16 | 2013-08-20 | Given Imaging Ltd. | Device and method for detecting in-vivo pathology |
| GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
| US20130202499A1 (en) * | 2012-01-31 | 2013-08-08 | Kimberly-Clark Worldwide, Inc. | Composition and Sensor for Detecting Occult Blood |
| US9091682B1 (en) | 2014-05-01 | 2015-07-28 | Steven M Hacker | Tissue specimen bottle with color indicator in lid verifying and confirming presence of human tissue or blood contained in specimen bottle |
| CN106124498A (zh) * | 2016-07-12 | 2016-11-16 | 北京珍草中医药技术开发中心 | 一种隐血检测试剂盒及其应用 |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL126365C (es) * | 1963-06-24 | |||
| US3933594A (en) * | 1974-08-16 | 1976-01-20 | Polaroid Corporation | Method and device for determining the concentration of a substance in a fluid |
| CS175782B1 (es) * | 1974-10-16 | 1977-05-31 | ||
| CS176664B1 (es) * | 1975-02-14 | 1977-06-30 | ||
| NL7608492A (nl) * | 1975-08-06 | 1977-02-08 | Riedel De Haen Ag | Diagnostisch middel voor het aantonen van bloed en andere peroxidasehoudende stoffen in lichaamsvloeistoffen. |
| US3986833A (en) * | 1975-09-08 | 1976-10-19 | Miles Laboratories, Inc. | Test composition, device, and method for the detection of peroxidatively active substances |
| JPS5263794A (en) * | 1975-11-21 | 1977-05-26 | Shionogi Seiyaku Kk | Test piece for latent blood |
| FR2353856A1 (fr) * | 1976-06-02 | 1977-12-30 | Chateau Guy | Ruban destine a servir de support a une reaction par exemple chimique ou biochimique, et procede d'analyse le mettant en oeuvre |
| US4071317A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances and process for preparing same |
| US4071318A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| US4071321A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| DE2716060C3 (de) * | 1977-04-09 | 1980-06-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierte Schnelldiagnostica mit Oxydationsindikatoren |
| DE2716061C2 (de) * | 1977-04-09 | 1982-03-25 | Boehringer Mannheim Gmbh, 6800 Mannheim | Guajaconsäure A, Verfahren zu ihrer Herstellung und die Verwendung dieser Substanz als diagnostische Mittel |
| US4247631A (en) * | 1979-01-31 | 1981-01-27 | Millipore Corporation | Reagent and method for the analytic determination of hydrogen peroxide |
| DE2906732C2 (de) * | 1979-02-21 | 1981-10-01 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Reagenz zur Bestimmung der Peroxidase |
| US4290773A (en) * | 1979-11-13 | 1981-09-22 | Miles Laboratories, Inc. | Stabilization of benzidine-type indicators with various enhancers |
| US4279993A (en) * | 1979-11-13 | 1981-07-21 | Magers Thomas A | Indicator composition and test device containing amine oxide, and method of use |
| US4333734A (en) * | 1980-01-18 | 1982-06-08 | Sloan-Kettering Institute For Cancer Research | Diagnostic device for fecal occult blood and method of use |
| US4486536A (en) * | 1982-05-28 | 1984-12-04 | Smithkline Diagnostics, Inc. | Specimen slide for occult blood testing |
| US4460684A (en) * | 1982-08-02 | 1984-07-17 | Miles Laboratories, Inc. | Ascorbate-resistant broad range glucose test composition, test device and method |
| US4493892A (en) * | 1982-12-20 | 1985-01-15 | Memorial Hospital For Cancer & Allied Diseases | Solvent system for peroxidase inhibitor reagent for fecal occult blood determinations |
| US4587220A (en) * | 1983-03-28 | 1986-05-06 | Miles Laboratories, Inc. | Ascorbate interference-resistant composition, device and method for the determination of peroxidatively active substances |
| US4543338A (en) * | 1983-06-03 | 1985-09-24 | Miles Laboratories, Inc. | Wipe-off test device |
| US4556640A (en) * | 1983-06-29 | 1985-12-03 | Miles Laboratories, Inc. | Stabilized test composition, device and method for the determination of peroxidatively active substances |
| US4562043A (en) * | 1983-09-09 | 1985-12-31 | Mennen Frederick C | Self-contained swab cartridge apparatus for detecting occult blood |
| US4742002A (en) * | 1984-01-16 | 1988-05-03 | Helena Laboratories Corporation | Test kit and method for determining the presence of blood in a specimen and for testing the effectiveness of peroxidase inactivating solution |
| EP0355864A3 (en) * | 1984-03-15 | 1991-09-18 | Wako Pure Chemical Industries, Ltd. | Method of quantitatively measuring an oxidative substance by using triphenyl methane type leuco compounds as coloring matter |
| DE3433946A1 (de) * | 1984-09-15 | 1986-03-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Mittel und verfahren zum nachweis von wasserstoffperoxid |
| US4820646A (en) * | 1984-12-11 | 1989-04-11 | Litmus Concepts, Inc. | Fecal occult blood test method |
| US4942132A (en) * | 1984-12-11 | 1990-07-17 | Litmus Concepts, Inc. | Reagent composition for fecal occult blood tests |
| US5068197A (en) * | 1984-12-11 | 1991-11-26 | Litmus Concepts, Inc. | Fecal occult blood test methods |
| US4937197A (en) * | 1984-12-11 | 1990-06-26 | Litmus Concepts, Inc. | Fecal occult blood test method |
| US4939097A (en) * | 1986-06-02 | 1990-07-03 | Litmus Concepts, Inc. | Fecal occult blood test methods |
| US4615982A (en) * | 1984-12-11 | 1986-10-07 | Lawrence Paul J | Fecal occult blood test |
| US4971914A (en) * | 1984-12-11 | 1990-11-20 | Litmus Concepts, Inc. | Developer for fecal occult blood tests |
| DE3541979A1 (de) * | 1985-11-28 | 1987-06-04 | Behringwerke Ag | Mittel zur bestimmung von peroxidase-aktivitaet mit stabilisator, verfahren zur herstellung und seine verwendung |
| US4719181A (en) * | 1985-12-20 | 1988-01-12 | Warner-Lambert Company | Free flowing granular indicator material for peroxidase-like activity |
| US4645743A (en) * | 1986-03-11 | 1987-02-24 | Smithkline Diagnostics, Inc. | Method and device for collecting and testing for fecal occult blood |
| US4818702A (en) * | 1986-06-02 | 1989-04-04 | Litmus Concepts, Inc. | Fecal occult blood test reagent |
| US4828983A (en) * | 1986-07-10 | 1989-05-09 | Eastman Kodak Company | Use of phenols and anilines to increase the rate of peroxidase catalyzed oxidation of leuco dyes |
| IL82840A0 (en) * | 1986-07-15 | 1987-12-20 | Savyon Diagnostics Ltd | Method and compositions for the determination of occult blood |
| US5178831A (en) * | 1986-10-08 | 1993-01-12 | Dai Nippon Insatsu Kab Ushiki Kaisha | Device for testing body fluids |
| US4789629A (en) * | 1986-11-24 | 1988-12-06 | Smithkline Beckman Corporation | Method and device for collecting and testing for fecal occult blood |
| EP0281251A3 (en) * | 1987-02-04 | 1988-09-28 | International Immunoassay Laboratories, Inc. | A method for preparing a fecal sample composition for immunoassay testing |
| JPH0684970B2 (ja) * | 1987-03-31 | 1994-10-26 | 株式会社京都医科学研究所 | 糞便中の潜血検出方法 |
| US5081040A (en) * | 1987-06-29 | 1992-01-14 | Helena Laboratories Corporation | Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes |
| JP2645429B2 (ja) * | 1987-09-16 | 1997-08-25 | スミスクライン・ダイアグノスティクス・インコーポレイテッド | 改良された糞便潜血用テスト |
| US5310680A (en) * | 1987-09-16 | 1994-05-10 | Smithkline Diagnostics, Inc. | Test for fecal occult blood |
| US4895798A (en) * | 1987-11-13 | 1990-01-23 | Miles, Inc. | Test devices for determination of occult blood |
| JP2610460B2 (ja) * | 1987-12-03 | 1997-05-14 | 大日本印刷株式会社 | 潜血検出用組成物およびそれを用いた検査体 |
| DE3883189T2 (de) * | 1987-12-18 | 1994-01-05 | Fuji Photo Film Co Ltd | Trocken-flüssiges analytisches Element. |
| US5053342A (en) * | 1987-12-24 | 1991-10-01 | Litmus Concepts, Inc. | Fecal occult blood test reagents |
| US5084395A (en) * | 1988-05-25 | 1992-01-28 | Boehringer Mannheim Gmbh | Reducible indicator compositions containing pyrogallol derivatives |
| US5013669A (en) * | 1988-06-01 | 1991-05-07 | Smithkline Diagnostics, Inc. | Mass producible biologically active solid phase devices |
| US5196167A (en) * | 1989-04-04 | 1993-03-23 | Helena Laboratories Corporation | Fecal occult blood test product with positive and negative controls |
| US5064766A (en) * | 1989-10-18 | 1991-11-12 | Wardlaw Stephen C | Method for differentiating the source of occult gastrointestinal bleeding |
| US5089420A (en) * | 1990-01-30 | 1992-02-18 | Miles Inc. | Composition, device and method of assaying for a peroxidatively active substance utilizing amine borate compounds |
| US5182213A (en) * | 1991-03-18 | 1993-01-26 | Miles Inc. | Method for detecting the presence of peroxidatively active substance in basic media |
| US5447868A (en) * | 1993-09-14 | 1995-09-05 | Propper Manufacturing Co. Inc. | Method, reagent and kit for the detection of fecal occult blood |
-
1993
- 1993-09-14 US US08/121,072 patent/US5447868A/en not_active Expired - Lifetime
-
1994
- 1994-09-13 AU AU76860/94A patent/AU7686094A/en not_active Abandoned
- 1994-09-13 DE DE69411928T patent/DE69411928T2/de not_active Expired - Lifetime
- 1994-09-13 WO PCT/US1994/010267 patent/WO1995008120A1/en not_active Ceased
- 1994-09-13 EP EP94927402A patent/EP0720746B1/en not_active Expired - Lifetime
- 1994-09-13 ES ES94927402T patent/ES2122324T3/es not_active Expired - Lifetime
- 1994-09-13 CA CA002171872A patent/CA2171872C/en not_active Expired - Lifetime
- 1994-09-13 DK DK94927402T patent/DK0720746T3/da active
-
1995
- 1995-05-12 US US08/439,603 patent/US5563071A/en not_active Expired - Lifetime
- 1995-05-12 US US08/439,602 patent/US6410336B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69411928T2 (de) | 1999-02-18 |
| AU7686094A (en) | 1995-04-03 |
| US5447868A (en) | 1995-09-05 |
| US6410336B1 (en) | 2002-06-25 |
| DE69411928D1 (de) | 1998-08-27 |
| EP0720746A1 (en) | 1996-07-10 |
| EP0720746B1 (en) | 1998-07-22 |
| CA2171872C (en) | 2004-11-30 |
| DK0720746T3 (da) | 1999-02-22 |
| WO1995008120A1 (en) | 1995-03-23 |
| US5563071A (en) | 1996-10-08 |
| CA2171872A1 (en) | 1995-03-23 |
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