ES2126262T3 - Cassette de expresion que comprende una region promotora salida del gen pho4 de schizosaccharomyces pombe. - Google Patents

Cassette de expresion que comprende una region promotora salida del gen pho4 de schizosaccharomyces pombe.

Info

Publication number
ES2126262T3
ES2126262T3 ES95911383T ES95911383T ES2126262T3 ES 2126262 T3 ES2126262 T3 ES 2126262T3 ES 95911383 T ES95911383 T ES 95911383T ES 95911383 T ES95911383 T ES 95911383T ES 2126262 T3 ES2126262 T3 ES 2126262T3
Authority
ES
Spain
Prior art keywords
pct
schizosaccharomyces pombe
expression cassette
gene
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95911383T
Other languages
English (en)
Inventor
Eric Jacobs
Nathalie Silvestre
Ernst Schweingruber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Application granted granted Critical
Publication of ES2126262T3 publication Critical patent/ES2126262T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO COMBINADO DE DOS CASILLAS DE EXPRESION, PERMITIENDO UNA LA EXPRESION DE UN FRAGMENTO DE ADN DE INTERES BAJO EL CONTROL DE UNA REGION PROMOTORA REGULABLE POR LA TIANINA Y PERMITIENDO LA OTRA LA EXPRESION DE UN GEN ACTIVADOR, ASI COMO LAS CELULAS HUESPEDES EN LAS QUE SE PONE EN PRACTICA TAL USO. LA PRESENTE INVENCION SE REFIERE TAMBIEN A UNA CASILLA DE EXPRESION EN LA QUE EL FRAGMENTO DE ADN DE INTERES Y BAJO EL CONTROL DE UNA REGION PROMOTORA OBTENIDA DEL GEN PHO-4 DE SCHIZOSACCHAROMYCES POMBE Y LOS VECTORES Y CELULAS QUE COMPRENDEN TAL CASILLA DE EXPRESION. POR FIN, LA INVENCION COMPRENDE UN NUEVO PROCEDIMIENTO DE PRODUCCION DE UNA PROTEINA DE INTERES.
ES95911383T 1994-03-10 1995-03-09 Cassette de expresion que comprende una region promotora salida del gen pho4 de schizosaccharomyces pombe. Expired - Lifetime ES2126262T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9402767A FR2717187B1 (fr) 1994-03-10 1994-03-10 Usage combiné de deux cassettes d'expression pour la production d'une protéine d'intérêt.

Publications (1)

Publication Number Publication Date
ES2126262T3 true ES2126262T3 (es) 1999-03-16

Family

ID=9460880

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95911383T Expired - Lifetime ES2126262T3 (es) 1994-03-10 1995-03-09 Cassette de expresion que comprende una region promotora salida del gen pho4 de schizosaccharomyces pombe.

Country Status (12)

Country Link
US (1) US5834237A (es)
EP (1) EP0749489B1 (es)
JP (1) JPH09509843A (es)
AT (1) ATE174630T1 (es)
AU (1) AU700159B2 (es)
CA (1) CA2185103A1 (es)
DE (1) DE69506691T2 (es)
DK (1) DK0749489T3 (es)
ES (1) ES2126262T3 (es)
FR (1) FR2717187B1 (es)
GR (1) GR3029565T3 (es)
WO (1) WO1995024491A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709858B1 (en) 1997-11-03 2004-03-23 The Arizona Board Of Regents On Behalf Of The University Of Arizona Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
US7098191B2 (en) 1997-11-03 2006-08-29 The Arizona Board Of Reagents Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
AU1377299A (en) * 1997-11-03 1999-05-24 Arizona Board Of Regents On Behalf Of The University Of Arizona, The Hyperthermic inducible expression vectors for gene therapy and methods of use thereof
EP2159288A3 (en) * 2000-02-11 2014-02-12 Metabolix, Inc. Multi-gene expression constructs containing modified inteins
US7300792B2 (en) * 2002-04-04 2007-11-27 University Of Tennessee Research Foundation Lux expression in eukaryotic cells
EP2314629B2 (en) 2002-07-18 2022-11-16 Merus N.V. Recombinant production of mixtures of antibodies
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
WO2004106375A1 (en) 2003-05-30 2004-12-09 Merus Biopharmaceuticals B.V. I.O. Fab library for the preparation of anti vegf and anti rabies virus fabs
AU2005205412B2 (en) * 2004-01-20 2011-08-11 Merus N.V. Mixtures of binding proteins
DK2838918T3 (da) 2012-04-20 2019-08-12 Merus Nv Fremgangsmåder og midler til fremstilling af heterodimere ig-lignende molekyler
US11180572B2 (en) 2012-07-06 2021-11-23 Genmab B.V. Dimeric protein with triple mutations
EP3976116A4 (en) 2019-05-30 2023-08-23 490 Biotech, Inc. EXPRESSION OF BIOLUMINESCENCE IN CELLS AND METHODS OF USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1236844B (it) * 1989-10-19 1993-04-22 Mini Ricerca Scient Tecnolog Clonaggio del gene regolabile nmt1 di schizosaccharomyces pombe e impiego delle sequenze di controllo della regolazione della trascrizione di tale gene per l'espressione regolabile di geni eterologhi

Also Published As

Publication number Publication date
EP0749489A1 (fr) 1996-12-27
DK0749489T3 (da) 1999-08-23
GR3029565T3 (en) 1999-06-30
FR2717187B1 (fr) 1996-05-31
AU700159B2 (en) 1998-12-24
JPH09509843A (ja) 1997-10-07
WO1995024491A1 (fr) 1995-09-14
US5834237A (en) 1998-11-10
DE69506691D1 (de) 1999-01-28
AU1896895A (en) 1995-09-25
FR2717187A1 (fr) 1995-09-15
DE69506691T2 (de) 1999-06-10
ATE174630T1 (de) 1999-01-15
EP0749489B1 (fr) 1998-12-16
CA2185103A1 (fr) 1995-09-14

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