DK0910642T3 - Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi - Google Patents
Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungiInfo
- Publication number
- DK0910642T3 DK0910642T3 DK97928925T DK97928925T DK0910642T3 DK 0910642 T3 DK0910642 T3 DK 0910642T3 DK 97928925 T DK97928925 T DK 97928925T DK 97928925 T DK97928925 T DK 97928925T DK 0910642 T3 DK0910642 T3 DK 0910642T3
- Authority
- DK
- Denmark
- Prior art keywords
- hemoprotein
- fungal cell
- filamentous fungal
- nucleic acid
- increasing
- Prior art date
Links
- 241000233866 Fungi Species 0.000 title 1
- 230000002538 fungal effect Effects 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 230000001851 biosynthetic effect Effects 0.000 abstract 3
- 150000003278 haem Chemical class 0.000 abstract 3
- 150000007523 nucleic acids Chemical group 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
- C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66275296A | 1996-06-10 | 1996-06-10 | |
| US4115897P | 1997-03-17 | 1997-03-17 | |
| PCT/US1997/010003 WO1997047746A1 (en) | 1996-06-10 | 1997-06-09 | A method for increasing hemoprotein production in filamentous fungi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0910642T3 true DK0910642T3 (da) | 2004-08-09 |
Family
ID=26717857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97928925T DK0910642T3 (da) | 1996-06-10 | 1997-06-09 | Fremgangsmåde til at öge hæmoproteinproduktionen i filamentöse fungi |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6100057A (da) |
| EP (1) | EP0910642B1 (da) |
| JP (1) | JP3462218B2 (da) |
| CN (1) | CN1267556C (da) |
| AT (1) | ATE265534T1 (da) |
| AU (1) | AU3307797A (da) |
| DE (1) | DE69728878T2 (da) |
| DK (1) | DK0910642T3 (da) |
| WO (1) | WO1997047746A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1267556C (zh) * | 1996-06-10 | 2006-08-02 | 诺沃奇梅兹有限公司 | 提高丝状真菌中血红素蛋白产量的方法 |
| WO1997047753A1 (en) * | 1996-06-10 | 1997-12-18 | Novo Nordisk Biotech, Inc. | Aspergillus porphobilinogen synthases and nucleic acids encoding same |
| DK1032683T3 (da) * | 1997-11-17 | 2005-06-06 | Novozymes Inc | Polypeptider med 5-aminolevulinsyre-syntase-aktivitet og nukleinsyrer, der koder for disse |
| CN1279719A (zh) * | 1997-11-17 | 2001-01-10 | 诺沃诺尔迪斯克生物技术有限公司 | 具有尿卟啉原脱羧酶活性的多肽和编码该多肽的核酸 |
| US6033892A (en) * | 1998-11-16 | 2000-03-07 | Novo Nordis Biotech, Inc. | Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same |
| CN1281510A (zh) * | 1997-12-08 | 2001-01-24 | 诺沃诺尔迪斯克生物技术有限公司 | 提高真菌突变体中血红素蛋白产量的方法 |
| EP2287296A1 (en) | 2000-06-26 | 2011-02-23 | Novozymes A/S | Lipolytic enzyme |
| AU2003231028A1 (en) | 2002-04-22 | 2003-11-03 | Novozymes Biotech, Inc. | Methods for increasing homologous recombination of a nucleic acid sequence |
| EP1499733B1 (en) | 2002-04-22 | 2010-03-10 | Novozymes, Inc. | Methods for preparing variants of a dna sequence in filamentous fungi |
| US7183091B2 (en) * | 2003-02-19 | 2007-02-27 | Nugen Bioscience (Taiwan) Co., Ltd. | Sulfite reductase, the process for producing the same and the use thereof |
| US20050089972A1 (en) * | 2003-08-01 | 2005-04-28 | Claudia Schmidt-Dannert | Production of porphyrins |
| KR102381965B1 (ko) † | 2013-01-11 | 2022-04-04 | 임파서블 푸즈 인크. | 소비재를 위한 방법 및 조성물 |
| JP6759103B2 (ja) | 2014-03-31 | 2020-09-23 | インポッシブル フーズ インコーポレイテッド | ひき肉レプリカ |
| EP3294762B1 (en) | 2015-05-11 | 2022-01-19 | Impossible Foods Inc. | Expression constructs and methods of genetically engineering methylotrophic yeast |
| JP6615525B2 (ja) * | 2015-07-30 | 2019-12-04 | シスメックス株式会社 | ヘムタンパク質の生産方法 |
| CN105483147B (zh) * | 2016-01-22 | 2019-05-03 | 吉林大学 | 一种与致病力相关的灰霉病菌基因BcUdc1及其应用 |
| CN108251441A (zh) * | 2017-12-28 | 2018-07-06 | 广州天宝颂原生物科技开发有限公司 | 一种链亲和素融合光敏色素的荧光标记物的制备方法 |
| KR20210153106A (ko) | 2019-04-17 | 2021-12-16 | 임파서블 푸즈 인크. | 단백질 생산을 위한 물질 및 방법 |
| PH12021552674A1 (en) | 2019-04-25 | 2022-07-04 | Impossible Foods Inc | Strains and methods for production of heme-containing proteins |
| WO2023039012A1 (en) * | 2021-09-07 | 2023-03-16 | The Regents Of The University Of California | Expression of heme biosynthesis and heme proteins in edible filamentous fungi |
| US20230340077A1 (en) * | 2021-12-01 | 2023-10-26 | Luyef Biotechnologies Inc. | Production of myoglobin from trichoderma using a feeding media |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902620A (en) | 1985-04-25 | 1990-02-20 | Eli Lilly And Company | Novel DNA for expression of delta-aminolevulinic acid synthetase and related method |
| IL88095A0 (en) * | 1987-10-23 | 1989-06-30 | California Inst Of Techn | Dna sequences,proteins and gene preparations |
| CA2106485A1 (en) * | 1991-03-22 | 1992-09-23 | Henrik Dalboge | Process for producing heme proteins |
| WO1993025697A1 (en) * | 1992-06-15 | 1993-12-23 | California Institute Of Technology | Enhancement of cell growth by expression of cloned oxygen-binding proteins |
| US5824511A (en) * | 1995-08-01 | 1998-10-20 | University Technology Corporation | Method for enhancing the production of hemoproteins |
| CN1267556C (zh) * | 1996-06-10 | 2006-08-02 | 诺沃奇梅兹有限公司 | 提高丝状真菌中血红素蛋白产量的方法 |
-
1997
- 1997-06-09 CN CNB971953732A patent/CN1267556C/zh not_active Expired - Lifetime
- 1997-06-09 AT AT97928925T patent/ATE265534T1/de not_active IP Right Cessation
- 1997-06-09 WO PCT/US1997/010003 patent/WO1997047746A1/en not_active Ceased
- 1997-06-09 EP EP97928925A patent/EP0910642B1/en not_active Expired - Lifetime
- 1997-06-09 DK DK97928925T patent/DK0910642T3/da active
- 1997-06-09 DE DE69728878T patent/DE69728878T2/de not_active Expired - Lifetime
- 1997-06-09 JP JP50176198A patent/JP3462218B2/ja not_active Expired - Lifetime
- 1997-06-09 AU AU33077/97A patent/AU3307797A/en not_active Abandoned
- 1997-06-09 US US08/871,267 patent/US6100057A/en not_active Expired - Lifetime
-
2000
- 2000-07-18 US US09/618,419 patent/US6261827B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997047746A1 (en) | 1997-12-18 |
| US6261827B1 (en) | 2001-07-17 |
| CN1267556C (zh) | 2006-08-02 |
| AU3307797A (en) | 1998-01-07 |
| ATE265534T1 (de) | 2004-05-15 |
| DE69728878D1 (de) | 2004-06-03 |
| JP3462218B2 (ja) | 2003-11-05 |
| DE69728878T2 (de) | 2005-04-07 |
| CN1221453A (zh) | 1999-06-30 |
| EP0910642A1 (en) | 1999-04-28 |
| JP2000512151A (ja) | 2000-09-19 |
| EP0910642B1 (en) | 2004-04-28 |
| US6100057A (en) | 2000-08-08 |
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