ES2127188T3 - Procedimiento para almacenar globulos rojos con mantenimiento prolongado de las concentraciones celulares de atp y 2,3-dpg. - Google Patents

Procedimiento para almacenar globulos rojos con mantenimiento prolongado de las concentraciones celulares de atp y 2,3-dpg.

Info

Publication number
ES2127188T3
ES2127188T3 ES90915582T ES90915582T ES2127188T3 ES 2127188 T3 ES2127188 T3 ES 2127188T3 ES 90915582 T ES90915582 T ES 90915582T ES 90915582 T ES90915582 T ES 90915582T ES 2127188 T3 ES2127188 T3 ES 2127188T3
Authority
ES
Spain
Prior art keywords
dpg
atp
procedure
cell concentrations
prolonged maintenance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90915582T
Other languages
English (en)
Inventor
Harold T Meryman
Marne Hornblower
Ralph L Syring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Application granted granted Critical
Publication of ES2127188T3 publication Critical patent/ES2127188T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA INVENCION PROPORCIONA UN METODO MEJORADO PARA PROLONGAR LA VIDA ENCAPUSADA DE CELULAS SANGUINEAS DE TRANSFUSION DECRECIENDO LA OSMOLARIDAD DE LA SOLUCION EN SUSPENSO E INCREMENTANDO EL PH INTRACELULAR DE LAS CELULAS ANTES DE SU ALMACENAMIENTO. ESTA INVENCION PROPORCIONA TAMBIEN METODOS POR LOS QUE SE INCREMENTA EL PH INTRACELULAR. ESTOS METODOS INCLUYEN EL RECOLECTAR LAS CELULAS EN UN ANTICOAGULANTE EN UN PH DE 70 O MAYOR Y/O LAVAR, DILUIR O RESUSPENDER LAS CELULAS ANTES DE SU ALMACENAMIENTO EN UNA SOLUCION TAMPON BIOLOGICAMENTE COMPATIBLE QUE CONTIENE AL MENOS UN ANION NO PENETRANTE O SUSTANCIALMENTE NO PENETRANTE O NO ELECTROLITO Y SUSTANCIALMENTE LIBRE DE IONES DE CLORURO.
ES90915582T 1989-10-06 1990-10-09 Procedimiento para almacenar globulos rojos con mantenimiento prolongado de las concentraciones celulares de atp y 2,3-dpg. Expired - Lifetime ES2127188T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41776189A 1989-10-06 1989-10-06

Publications (1)

Publication Number Publication Date
ES2127188T3 true ES2127188T3 (es) 1999-04-16

Family

ID=23655307

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90915582T Expired - Lifetime ES2127188T3 (es) 1989-10-06 1990-10-09 Procedimiento para almacenar globulos rojos con mantenimiento prolongado de las concentraciones celulares de atp y 2,3-dpg.

Country Status (13)

Country Link
EP (1) EP0494957B1 (es)
JP (1) JP3069613B2 (es)
KR (1) KR0185415B1 (es)
AT (1) ATE176126T1 (es)
AU (1) AU656718B2 (es)
DE (1) DE69032923T2 (es)
ES (1) ES2127188T3 (es)
FI (1) FI107703B (es)
HU (1) HU215185B (es)
IE (1) IE903603A1 (es)
IL (1) IL95912A (es)
WO (1) WO1991004659A1 (es)
ZA (1) ZA908043B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0509083B1 (en) * 1990-11-07 1997-07-16 Baxter International Inc. Red blood cell storage solution
DE69929691T2 (de) 1998-05-26 2006-09-07 Lifecell Corp. Cryokonservierung menschlicher roter blutzellen
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
US9314014B2 (en) 2004-02-18 2016-04-19 University Of Maryland, Baltimore Compositions and methods for the storage of red blood cells
US20090035289A1 (en) 2005-09-26 2009-02-05 Lifecell Corporation Dry platelet composition
DE602008005349D1 (de) 2008-12-29 2011-04-14 Fiat Ricerche Brennstoffeinspritzsystem mit hoher Betriebswiederholbarkeit und -stabilität für einen Verbrennungsmotor
WO2011046963A1 (en) 2009-10-12 2011-04-21 New Health Sciences, Inc. Oxygen depletion devices and methods for removing oxygen from red blood cells
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CA2781866C (en) 2009-10-12 2019-12-03 New Health Sciences, Inc. Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
JP5930483B2 (ja) 2010-08-25 2016-06-08 ニュー・ヘルス・サイエンシーズ・インコーポレイテッドＮｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 保存中の赤血球の品質及び生存を高める方法
ES2793484T3 (es) 2010-11-05 2020-11-16 Hemanext Inc Irradiación de glóbulos rojos y almacenamiento anaeróbico
US10130751B2 (en) * 2011-03-11 2018-11-20 Fenwal, Inc. Membrane separation and washing devices, systems and methods employing same, and data management systems and methods
CN103702557A (zh) 2011-03-16 2014-04-02 梅奥医学教育和研究基金会 用于延长红细胞制剂和血小板制剂的可用储存的方法和材料
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
ES2923571T3 (es) 2011-08-10 2022-09-28 Hemanext Inc Dispositivo integrado de filtrado de leucocitos, oxígeno y/o CO2 y separación de plasma
JP5568103B2 (ja) * 2012-02-20 2014-08-06 ユニバーシティ・オブ・シンシナティ 赤血球の保存のための組成物及び方法
US9877476B2 (en) 2013-02-28 2018-01-30 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
WO2014162435A1 (ja) 2013-04-01 2014-10-09 テルモ株式会社 赤血球保存液、保存液収納容器、赤血球保存液の製造方法および血液バッグシステム
MX2017011595A (es) 2015-03-10 2018-06-15 New Health Sciences Inc Kits, dispositivos descartables para reducir el oxígeno y métodos para usarlos.
AU2016253005B2 (en) 2015-04-23 2020-07-09 Hemanext Inc. Anaerobic blood storage containers
BR122021024421B1 (pt) 2015-05-18 2022-05-03 Hemanext Inc Usos de um produto de sangue total armazenado reduzido de oxigênio com plaquetas
WO2017205590A2 (en) 2016-05-27 2017-11-30 New Health Sciences, Inc. Anaerobic blood storage and pathogen inactivation method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD152719A1 (de) * 1980-09-02 1981-12-09 Klinke Birgit Verfahren zur konservierung von erythrozyten
US4585735A (en) * 1984-07-19 1986-04-29 American National Red Cross Prolonged storage of red blood cells
FR2581289A1 (fr) * 1985-05-06 1986-11-07 Rgl Transfusion Sanguine Centr Solution synthetique pour la conservation prolongee de concentres erythrocytaires
DE3722984A1 (de) * 1987-07-11 1989-01-19 Biotest Pharma Gmbh Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten

Also Published As

Publication number Publication date
HUT64440A (en) 1994-01-28
IE903603A1 (en) 1991-04-10
FI107703B (fi) 2001-09-28
HU215185B (hu) 1998-10-28
EP0494957B1 (en) 1999-01-27
ATE176126T1 (de) 1999-02-15
DE69032923T2 (de) 1999-08-19
FI921488A0 (fi) 1992-04-03
IL95912A0 (en) 1991-07-18
EP0494957A4 (en) 1993-03-10
EP0494957A1 (en) 1992-07-22
JPH05503075A (ja) 1993-05-27
HU9201160D0 (en) 1992-08-28
AU656718B2 (en) 1995-02-16
KR920702907A (ko) 1992-12-17
IL95912A (en) 1998-08-16
ZA908043B (en) 1991-07-31
FI921488L (fi) 1992-04-03
DE69032923D1 (de) 1999-03-11
WO1991004659A1 (en) 1991-04-18
AU6604090A (en) 1991-04-28
KR0185415B1 (en) 1999-04-01
JP3069613B2 (ja) 2000-07-24

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