ES2132384T3 - Heteroaril alquil tiopiridina sustituida para la lucha contra bacterias helicobacter. - Google Patents

Heteroaril alquil tiopiridina sustituida para la lucha contra bacterias helicobacter.

Info

Publication number
ES2132384T3
ES2132384T3 ES94907547T ES94907547T ES2132384T3 ES 2132384 T3 ES2132384 T3 ES 2132384T3 ES 94907547 T ES94907547 T ES 94907547T ES 94907547 T ES94907547 T ES 94907547T ES 2132384 T3 ES2132384 T3 ES 2132384T3
Authority
ES
Spain
Prior art keywords
thiopiridina
heteroaril
substituted
alkyl
fight against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94907547T
Other languages
English (en)
Inventor
Bernhard Kohl
Jorg Senn-Bilfinger
Gerhard Grundler
Wolfgang Opferkuch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of ES2132384T3 publication Critical patent/ES2132384T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), DONDE R SUP.1 , R SUP.2 , R{SUP.3}, R{SUP.4}, R{SUP.5}, R{SUP.6}, R{SUP.7}, M, N Y P TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION, SIENDO ADECUADOS PARA LA LUCHA CONTRA BACTERIAS HELICOBACTER.
ES94907547T 1993-02-17 1994-02-11 Heteroaril alquil tiopiridina sustituida para la lucha contra bacterias helicobacter. Expired - Lifetime ES2132384T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH50793 1993-02-17

Publications (1)

Publication Number Publication Date
ES2132384T3 true ES2132384T3 (es) 1999-08-16

Family

ID=4188595

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94907547T Expired - Lifetime ES2132384T3 (es) 1993-02-17 1994-02-11 Heteroaril alquil tiopiridina sustituida para la lucha contra bacterias helicobacter.

Country Status (11)

Country Link
US (1) US5587389A (es)
EP (1) EP0683776B1 (es)
JP (1) JPH08507054A (es)
AT (1) ATE178603T1 (es)
AU (1) AU674058B2 (es)
CA (1) CA2156258A1 (es)
DE (1) DE59408087D1 (es)
DK (1) DK0683776T3 (es)
ES (1) ES2132384T3 (es)
GR (1) GR3030288T3 (es)
WO (1) WO1994019346A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI964909A0 (fi) * 1994-06-10 1996-12-09 Byk Gulden Lomberg Chem Fab Substituoidut aryylialkyylitioalkyylipyridiinit Helicobacter-bakteerien torjumiseksi
CA2192206A1 (en) * 1994-06-10 1995-12-21 Bernhard Kohl Thiopyridines for use in the control of helicobacter bacteria
WO1996000224A1 (de) * 1994-06-23 1996-01-04 Byk Gulden Lomberg Chemische Fabrik Gmbh 4-s- und n-substituierte 6-alkylpyridine zur bekämpfung von helicobacter-bakterien
US6051570A (en) * 1997-05-30 2000-04-18 Dr. Reddy's Research Foundation Benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
DE19745692A1 (de) * 1997-07-24 1999-01-28 Bayer Ag Verfahren zur Herstellung von 2-Chlor-benzimidazol-Derivaten
RU2449805C1 (ru) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
ATE209914T1 (de) * 1990-09-14 2001-12-15 Byk Gulden Lomberg Chem Fab Verwendung von pyridylmethylsulfinyl-1h- benzimidazol derivaten zur behandlung durch helicobacter verursachter erkrankungen
WO1992012976A1 (fr) * 1991-01-16 1992-08-06 Yoshitomi Pharmaceutical Industries, Ltd. Compose de pyridine utilise comme medicament selectif et nouveau compose de pyridine
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions

Also Published As

Publication number Publication date
JPH08507054A (ja) 1996-07-30
US5587389A (en) 1996-12-24
EP0683776A1 (de) 1995-11-29
AU674058B2 (en) 1996-12-05
WO1994019346A1 (de) 1994-09-01
GR3030288T3 (en) 1999-09-30
DE59408087D1 (de) 1999-05-12
EP0683776B1 (de) 1999-04-07
ATE178603T1 (de) 1999-04-15
AU6108794A (en) 1994-09-14
DK0683776T3 (da) 1999-10-18
CA2156258A1 (en) 1994-09-01

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