ES2132547T3 - Solucion acuosa concentrada de argatroban. - Google Patents

Solucion acuosa concentrada de argatroban.

Info

Publication number
ES2132547T3
ES2132547T3 ES95400214T ES95400214T ES2132547T3 ES 2132547 T3 ES2132547 T3 ES 2132547T3 ES 95400214 T ES95400214 T ES 95400214T ES 95400214 T ES95400214 T ES 95400214T ES 2132547 T3 ES2132547 T3 ES 2132547T3
Authority
ES
Spain
Prior art keywords
concentrated aqueous
argatroban
aqueous solution
argatrobane
micel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95400214T
Other languages
English (en)
Inventor
Frederic Andre
Veronique Avril
Jean Montel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of ES2132547T3 publication Critical patent/ES2132547T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SOLUCIONES ACUOSAS CONCENTRADAS DE ARGATROBANO QUE CONTIENE ARGATROBANO, UN AGENTE FORMADOR DE MICELAS Y UNA SUSTANCIA LIPOIDE.
ES95400214T 1994-02-03 1995-02-02 Solucion acuosa concentrada de argatroban. Expired - Lifetime ES2132547T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401195A FR2715566B1 (fr) 1994-02-03 1994-02-03 Solutions aqueuses concentrées d'argatroban.

Publications (1)

Publication Number Publication Date
ES2132547T3 true ES2132547T3 (es) 1999-08-16

Family

ID=9459714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95400214T Expired - Lifetime ES2132547T3 (es) 1994-02-03 1995-02-02 Solucion acuosa concentrada de argatroban.

Country Status (24)

Country Link
US (1) US5679690A (es)
EP (1) EP0669131B1 (es)
JP (1) JP3027103B2 (es)
KR (1) KR100257692B1 (es)
CN (1) CN1054743C (es)
AT (1) ATE179327T1 (es)
AU (1) AU687133B2 (es)
CA (1) CA2141704C (es)
CZ (1) CZ284611B6 (es)
DE (1) DE69509279T2 (es)
DK (1) DK0669131T3 (es)
ES (1) ES2132547T3 (es)
FI (1) FI950459L (es)
FR (1) FR2715566B1 (es)
GR (1) GR3030149T3 (es)
HU (1) HU218220B (es)
IL (1) IL112527A (es)
NO (1) NO307324B1 (es)
NZ (1) NZ270445A (es)
PL (1) PL178586B1 (es)
RU (1) RU2136282C1 (es)
SK (1) SK12795A3 (es)
TW (1) TW436295B (es)
ZA (1) ZA95837B (es)

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US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
FR2793412B1 (fr) * 1999-05-11 2001-07-27 Synthelabo Formulations galeniques d'argatroban pour administration sous-cutanee
KR100399373B1 (ko) * 2000-12-20 2003-09-26 주식회사 아이센스 콜란산 고리를 포함하는 디글라이콜릭 디아마이드 유도체,그의 제조방법 및 용도
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
AU2002309528A1 (en) 2001-04-02 2002-10-15 Therasense, Inc. Blood glucose tracking apparatus and methods
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US8771183B2 (en) 2004-02-17 2014-07-08 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
WO2004083201A1 (ja) * 2003-03-20 2004-09-30 Mitsubishi Pharma Corporation アルギニンアミド類を含有する医薬製剤
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
EP1948133B1 (en) * 2005-09-01 2011-06-29 BAXTER INTERNATIONAL INC. (a Delaware corporation) Argatroban formulation comprising an acid as solubilizer
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US20080071158A1 (en) 2006-06-07 2008-03-20 Abbott Diabetes Care, Inc. Analyte monitoring system and method
WO2008027958A2 (en) * 2006-08-31 2008-03-06 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CA2669727C (en) * 2006-09-27 2014-10-28 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US7687516B2 (en) * 2006-09-27 2010-03-30 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US20100076019A1 (en) * 2006-10-11 2010-03-25 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
EP2231169B1 (en) 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
US7915290B2 (en) * 2008-02-29 2011-03-29 Baxter International Inc. Argatroban formulations and methods for making and using same
US20090221637A1 (en) * 2008-02-29 2009-09-03 Baxter International Inc. Solid-state salt argatroban formulations and methods for producing and using the same
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP2473099A4 (en) 2009-08-31 2015-01-14 Abbott Diabetes Care Inc ANALYTICAL MONITORING SYSTEM AND METHOD FOR POWERFUL AND NOISE MANAGEMENT
WO2011026147A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte signal processing device and methods
EP2482720A4 (en) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc METHOD AND APPARATUS FOR PROVIDING NOTIFICATION FUNCTION IN SUBSTANCE MONITORING SYSTEMS
CN102366410B (zh) * 2011-09-14 2013-05-29 海南灵康制药有限公司 一种阿加曲班脂质体注射剂
EP2775918B1 (en) 2011-11-07 2020-02-12 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US20150034098A1 (en) 2013-07-11 2015-02-05 Aqua Turf International, Inc. Air filtration mask with opening front cover
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
US20220218608A1 (en) * 2019-05-10 2022-07-14 Fordoz Pharma Corp. Injectable polymer nanoparticle compositions of antithrombotic agents and methods thereof
CN110478471B (zh) * 2019-09-17 2020-04-10 鲁南制药集团股份有限公司 一种阿加曲班注射液及其制备方法
US12176752B2 (en) 2020-07-03 2024-12-24 Tmeic Corporation Uninterruptible power supply system
EP4070658A1 (de) 2021-04-06 2022-10-12 BIORoxx GmbH Verwendung von blutgerinnungshemmenden verbindungen als rodentizide
CN113855635A (zh) * 2021-10-20 2021-12-31 陇南市第一人民医院 一种阿加曲班注射液脂质体及其制备方法

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Also Published As

Publication number Publication date
FR2715566A1 (fr) 1995-08-04
CA2141704C (fr) 2001-07-03
NO950377D0 (no) 1995-02-02
GR3030149T3 (en) 1999-08-31
JP3027103B2 (ja) 2000-03-27
ZA95837B (en) 1996-03-29
IL112527A0 (en) 1995-05-26
FI950459A0 (fi) 1995-02-02
SK12795A3 (en) 1995-08-09
HK1013623A1 (en) 1999-09-03
HU218220B (hu) 2000-06-28
AU1154395A (en) 1995-08-10
FR2715566B1 (fr) 1996-03-08
HUT71524A (en) 1995-12-28
CZ284611B6 (cs) 1999-01-13
CN1109754A (zh) 1995-10-11
RU95101387A (ru) 1997-02-27
PL178586B1 (pl) 2000-05-31
AU687133B2 (en) 1998-02-19
ATE179327T1 (de) 1999-05-15
KR950031042A (ko) 1995-12-18
DE69509279D1 (de) 1999-06-02
DK0669131T3 (da) 1999-11-01
EP0669131B1 (fr) 1999-04-28
EP0669131A1 (fr) 1995-08-30
RU2136282C1 (ru) 1999-09-10
NO950377L (no) 1995-08-04
CA2141704A1 (fr) 1995-08-04
DE69509279T2 (de) 1999-11-25
NZ270445A (en) 1995-07-26
US5679690A (en) 1997-10-21
NO307324B1 (no) 2000-03-20
CZ27195A3 (en) 1995-09-13
TW436295B (en) 2001-05-28
CN1054743C (zh) 2000-07-26
IL112527A (en) 1999-04-11
JPH07277980A (ja) 1995-10-24
PL307041A1 (en) 1995-08-07
FI950459A7 (fi) 1995-08-04
KR100257692B1 (ko) 2000-08-01
FI950459L (fi) 1995-08-04

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