ES2133150T3 - Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. - Google Patents
Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo.Info
- Publication number
- ES2133150T3 ES2133150T3 ES94103244T ES94103244T ES2133150T3 ES 2133150 T3 ES2133150 T3 ES 2133150T3 ES 94103244 T ES94103244 T ES 94103244T ES 94103244 T ES94103244 T ES 94103244T ES 2133150 T3 ES2133150 T3 ES 2133150T3
- Authority
- ES
- Spain
- Prior art keywords
- liposoma
- phospholipid
- bile acid
- aqueous
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003904 phospholipids Chemical class 0.000 abstract 6
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 4
- 239000002502 liposome Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 239000003613 bile acid Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
SE DESCRIBE UN SISTEMA DE LIPOSOMAS ACUOSO QUE CONTIENE EVENTUALMENTE JUNTO A UN DISOLVENTE ORGANICO, NO TOXICO, AL MENOS UN FOSFOLIPIDO ASI COMO AL MENOS UNA OTRA SUSTANCIA NO FOSFOLIPIDICA. LA SUSTANCIA NO FOSFOLIPIDICA SE TRATA DE UN ACIDO BILIAR, UNA SAL DE ACIDO BILIAR, UN DERIVADO DE ACIDO BILIAR Y/O UNA SAL DE UN DERIVADO DE ACIDO BILIAR. LA RELACION DE MASA DEL FOSFOLIPIDO A LA OTRA SUSTANCIA NO FOSFOLIPIDICA VARIA ENTRE 1 : 0,001 HASTA 1 : 0,1. SE PREVE UN PROCESO PARA LA ELABORACION DEL SISTEMA DE LIPOSOMAS, DONDE SE DISUELVE PRIMERO EL FOSFOLIPIDO CON LA OTRA SUSTANCIA AL MENOS NO FOSFOLIPIDICA EN UNA RELACION DE MASAS DESDE 1 : 0,001 HASTA 1 : 0,1 EN UN DISOLVENTE ORGANICO O SE DISPERSA, A CONTINUACION LA SOLUCION O LA DISPERSION SE REDUCE EN CANTIDAD Y A PARTIR DE AQUI SE AÑADE AGUA BAJO LA FORMACION DEL SISTEMA DE LIPOSOMAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4308121A DE4308121A1 (de) | 1993-03-15 | 1993-03-15 | Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2133150T3 true ES2133150T3 (es) | 1999-09-01 |
Family
ID=6482793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94103244T Expired - Lifetime ES2133150T3 (es) | 1993-03-15 | 1994-03-04 | Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0615746B1 (es) |
| JP (1) | JPH06321772A (es) |
| AT (1) | ATE181826T1 (es) |
| CA (1) | CA2119057C (es) |
| DE (2) | DE4308121A1 (es) |
| DK (1) | DK0615746T3 (es) |
| ES (1) | ES2133150T3 (es) |
| GR (1) | GR3030726T3 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2196978A1 (es) * | 2001-10-26 | 2003-12-16 | Univ Barcelona Autonoma | Composicion farmaceutica. |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19522694A1 (de) * | 1995-06-22 | 1997-01-02 | Vinas Jose Maria De Moragas | Teerhaltige Zusammensetzung und diese enthaltende pharmazeutische und kosmetische Zubereitung |
| DE10349979B4 (de) * | 2003-10-24 | 2006-05-18 | Sanofi-Aventis Deutschland Gmbh | Medikamentöse gezielte lokale Lipolyse |
| BRPI0516937A (pt) * | 2004-10-19 | 2008-09-23 | Max Planck Gesellschaft | formulações com alquilfosfocolinas na utilização de partìculas portadoras de carga negativa |
| DE102007015701A1 (de) | 2007-03-19 | 2008-09-25 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung |
| DE102010028365A1 (de) | 2010-04-29 | 2011-11-03 | Lichtblick Gmbh | Verwendung einer Phospholipid enthaltenden Zusammensetzung zur Entfernung von subkutanen Fettansammlungen |
| EP2857043B1 (en) * | 2012-05-31 | 2019-01-23 | Terumo Kabushiki Kaisha | pH-SENSITIVE CARRIER AND METHOD FOR PRODUCTION THEREOF, pH-SENSITIVE MEDICINE AND pH-SENSITIVE PHARMACEUTICAL COMPOSITION EACH CONTAINING SAID CARRIER, AND CULTURE METHOD USING SAID pH-SENSITIVE MEDICINE OR SAID pH-SENSITIVE PHARMACEUTICAL COMPOSITION |
| RU2725622C1 (ru) * | 2019-10-30 | 2020-07-03 | Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") | Фармацевтическая композиция для лечения и/или профилактики заболеваний печени |
| JP2024525832A (ja) * | 2021-07-16 | 2024-07-12 | スカイ・セラピューティクス・カンパニー・リミテッド | 胆汁酸又は胆汁酸塩の分子会合体を含む化粧料組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE464743B (sv) * | 1989-06-21 | 1991-06-10 | Ytkemiska Inst | Foerfarande foer framstaellning av laekemedelspartiklar |
| CA2067754C (en) * | 1990-08-24 | 2002-06-04 | Gregor Cevc | Preparation for the application of agents in mini-droplets |
| DE59307395D1 (de) * | 1992-07-08 | 1997-10-23 | Dianorm G Maierhofer Gmbh | Liposomen, verfahren zu ihrer herstellung und ihre verwendung zur herstellung eines arzneimittels |
-
1993
- 1993-03-15 DE DE4308121A patent/DE4308121A1/de not_active Withdrawn
-
1994
- 1994-03-04 EP EP94103244A patent/EP0615746B1/de not_active Expired - Lifetime
- 1994-03-04 ES ES94103244T patent/ES2133150T3/es not_active Expired - Lifetime
- 1994-03-04 DE DE59408450T patent/DE59408450D1/de not_active Expired - Lifetime
- 1994-03-04 AT AT94103244T patent/ATE181826T1/de active
- 1994-03-04 DK DK94103244T patent/DK0615746T3/da active
- 1994-03-11 JP JP6067947A patent/JPH06321772A/ja active Pending
- 1994-03-14 CA CA002119057A patent/CA2119057C/en not_active Expired - Lifetime
-
1999
- 1999-07-08 GR GR990401646T patent/GR3030726T3/el unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2196978A1 (es) * | 2001-10-26 | 2003-12-16 | Univ Barcelona Autonoma | Composicion farmaceutica. |
Also Published As
| Publication number | Publication date |
|---|---|
| GR3030726T3 (en) | 1999-11-30 |
| ATE181826T1 (de) | 1999-07-15 |
| CA2119057A1 (en) | 1994-09-16 |
| DE4308121A1 (de) | 1994-09-22 |
| CA2119057C (en) | 2004-01-20 |
| DE59408450D1 (de) | 1999-08-12 |
| JPH06321772A (ja) | 1994-11-22 |
| DK0615746T3 (da) | 1999-11-22 |
| EP0615746A1 (de) | 1994-09-21 |
| EP0615746B1 (de) | 1999-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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