ES2133150T3 - Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. - Google Patents
Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo.Info
- Publication number
- ES2133150T3 ES2133150T3 ES94103244T ES94103244T ES2133150T3 ES 2133150 T3 ES2133150 T3 ES 2133150T3 ES 94103244 T ES94103244 T ES 94103244T ES 94103244 T ES94103244 T ES 94103244T ES 2133150 T3 ES2133150 T3 ES 2133150T3
- Authority
- ES
- Spain
- Prior art keywords
- liposoma
- phospholipid
- bile acid
- aqueous
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003904 phospholipids Chemical class 0.000 abstract 6
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 4
- 239000002502 liposome Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 239000003613 bile acid Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
SE DESCRIBE UN SISTEMA DE LIPOSOMAS ACUOSO QUE CONTIENE EVENTUALMENTE JUNTO A UN DISOLVENTE ORGANICO, NO TOXICO, AL MENOS UN FOSFOLIPIDO ASI COMO AL MENOS UNA OTRA SUSTANCIA NO FOSFOLIPIDICA. LA SUSTANCIA NO FOSFOLIPIDICA SE TRATA DE UN ACIDO BILIAR, UNA SAL DE ACIDO BILIAR, UN DERIVADO DE ACIDO BILIAR Y/O UNA SAL DE UN DERIVADO DE ACIDO BILIAR. LA RELACION DE MASA DEL FOSFOLIPIDO A LA OTRA SUSTANCIA NO FOSFOLIPIDICA VARIA ENTRE 1 : 0,001 HASTA 1 : 0,1. SE PREVE UN PROCESO PARA LA ELABORACION DEL SISTEMA DE LIPOSOMAS, DONDE SE DISUELVE PRIMERO EL FOSFOLIPIDO CON LA OTRA SUSTANCIA AL MENOS NO FOSFOLIPIDICA EN UNA RELACION DE MASAS DESDE 1 : 0,001 HASTA 1 : 0,1 EN UN DISOLVENTE ORGANICO O SE DISPERSA, A CONTINUACION LA SOLUCION O LA DISPERSION SE REDUCE EN CANTIDAD Y A PARTIR DE AQUI SE AÑADE AGUA BAJO LA FORMACION DEL SISTEMA DE LIPOSOMAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4308121A DE4308121A1 (de) | 1993-03-15 | 1993-03-15 | Wäßriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2133150T3 true ES2133150T3 (es) | 1999-09-01 |
Family
ID=6482793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94103244T Expired - Lifetime ES2133150T3 (es) | 1993-03-15 | 1994-03-04 | Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0615746B1 (es) |
| JP (1) | JPH06321772A (es) |
| AT (1) | ATE181826T1 (es) |
| CA (1) | CA2119057C (es) |
| DE (2) | DE4308121A1 (es) |
| DK (1) | DK0615746T3 (es) |
| ES (1) | ES2133150T3 (es) |
| GR (1) | GR3030726T3 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2196978A1 (es) * | 2001-10-26 | 2003-12-16 | Univ Barcelona Autonoma | Composicion farmaceutica. |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19522694A1 (de) * | 1995-06-22 | 1997-01-02 | Vinas Jose Maria De Moragas | Teerhaltige Zusammensetzung und diese enthaltende pharmazeutische und kosmetische Zubereitung |
| DE10349979B4 (de) * | 2003-10-24 | 2006-05-18 | Sanofi-Aventis Deutschland Gmbh | Medikamentöse gezielte lokale Lipolyse |
| JP2008517023A (ja) * | 2004-10-19 | 2008-05-22 | マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | アルキルホスホコリンを含有する新規の負電荷担体を使用した配合物 |
| DE102007015701A1 (de) | 2007-03-19 | 2008-09-25 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung |
| DE102010028365A1 (de) | 2010-04-29 | 2011-11-03 | Lichtblick Gmbh | Verwendung einer Phospholipid enthaltenden Zusammensetzung zur Entfernung von subkutanen Fettansammlungen |
| WO2013180253A1 (ja) * | 2012-05-31 | 2013-12-05 | テルモ株式会社 | ｐＨ感受性担体およびその製造方法、並びに該担体を含むｐＨ感受性医薬、ｐＨ感受性医薬組成物およびこれを用いた培養方法 |
| RU2725622C1 (ru) * | 2019-10-30 | 2020-07-03 | Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") | Фармацевтическая композиция для лечения и/или профилактики заболеваний печени |
| WO2023287261A1 (ko) * | 2021-07-16 | 2023-01-19 | 주식회사 스카이테라퓨틱스 | 담즙산 또는 담즙산 염의 분자 회합체를 포함하는 화장료 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE464743B (sv) * | 1989-06-21 | 1991-06-10 | Ytkemiska Inst | Foerfarande foer framstaellning av laekemedelspartiklar |
| JP3765579B2 (ja) * | 1990-08-24 | 2006-04-12 | イーデーエーアー アーゲー | 作用物質投与用超微小滴状調剤 |
| EP0648114B1 (de) * | 1992-07-08 | 1997-09-17 | DIANORM G. Maierhofer GmbH | Liposomen, verfahren zu ihrer herstellung und ihre verwendung zur herstellung eines arzneimittels |
-
1993
- 1993-03-15 DE DE4308121A patent/DE4308121A1/de not_active Withdrawn
-
1994
- 1994-03-04 ES ES94103244T patent/ES2133150T3/es not_active Expired - Lifetime
- 1994-03-04 AT AT94103244T patent/ATE181826T1/de active
- 1994-03-04 DK DK94103244T patent/DK0615746T3/da active
- 1994-03-04 EP EP94103244A patent/EP0615746B1/de not_active Expired - Lifetime
- 1994-03-04 DE DE59408450T patent/DE59408450D1/de not_active Expired - Lifetime
- 1994-03-11 JP JP6067947A patent/JPH06321772A/ja active Pending
- 1994-03-14 CA CA002119057A patent/CA2119057C/en not_active Expired - Lifetime
-
1999
- 1999-07-08 GR GR990401646T patent/GR3030726T3/el unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2196978A1 (es) * | 2001-10-26 | 2003-12-16 | Univ Barcelona Autonoma | Composicion farmaceutica. |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2119057A1 (en) | 1994-09-16 |
| EP0615746A1 (de) | 1994-09-21 |
| DE59408450D1 (de) | 1999-08-12 |
| ATE181826T1 (de) | 1999-07-15 |
| DE4308121A1 (de) | 1994-09-22 |
| DK0615746T3 (da) | 1999-11-22 |
| JPH06321772A (ja) | 1994-11-22 |
| CA2119057C (en) | 2004-01-20 |
| GR3030726T3 (en) | 1999-11-30 |
| EP0615746B1 (de) | 1999-07-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59307395D1 (de) | Liposomen, verfahren zu ihrer herstellung und ihre verwendung zur herstellung eines arzneimittels | |
| DE3751258D1 (de) | Mikrokristalle, die eine aktive Substanz mit phospholipidischer Affinität enthalten und mindestens ein Phospholipid, Verfahren zur Herstellung. | |
| DE3779183D1 (de) | Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung. | |
| ES2133150T3 (es) | Sistema de liposomas acuoso, asi como procedimiento para la preparacion de un sistema de liposomas de este tipo. | |
| Skou et al. | Investigations on the effect of some local anaesthetics and other amines on the active transport of sodium through the isolated short-circuited frog skin | |
| ES2061920T3 (es) | Suspension acuosa de carboximetilcelulosa. | |
| KR860003249A (ko) | 피록시캄 1수화물의 제조 방법 | |
| IL72829A0 (en) | Stable,aqueous,acidic solution of cis-platinum,suitable for injection | |
| WO1989011522A2 (en) | Liquid aqueous laundry-conditioning agent | |
| DK0592880T3 (da) | Vandigt dispersionskoncentrat indeholdende linuron som aktivt stof. | |
| ES2072209A1 (es) | Composiciones para inducir resistencia a traqueomicosis en plantas. | |
| ES2163038T3 (es) | Procedimiento para la preparacion de clavulanato de potasio. | |
| JPS5632548A (en) | Preparation of stable type dioxazine violet pigment | |
| DE69631602D1 (de) | Wässrige dispersionen von polyamiden | |
| TW255822B (es) | ||
| ATE12257T1 (de) | Waessrige cholesterin-standardloesung und verfahren zu ihrer herstellung. | |
| JPS645460A (en) | Production of delaying gelatinous material | |
| Michels et al. | The Mechanism of Uncoupling by Picrate in Escherichia coli K‐12 Membrane Systems | |
| JPS6440453A (en) | Racemization of optically active serine | |
| ATE222887T1 (de) | Verfahren zur herstellung von inorganischen salzen von optisch aktiven phenylglycin-derivaten | |
| LOBACHEVA et al. | Investigation of toxic properties of preservatives to be used in water recycling systems | |
| TH13796A (th) | ขบวนการเตรียมอนุพันธ์ไตรฟลูออโรเบนซิน | |
| JPS5564845A (en) | Treating method for cation exchange membrane | |
| King et al. | Choline transport across a carbon tetrachloride phase containing a chloroform-methanol extract of brain | |
| ES2046182T3 (es) | Procedimiento para la preparacion de colorantes de 2-nitro-4-sulfamil-di-fenil-amina. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 615746 Country of ref document: ES |