ES2134844T3 - Proceso de produccion de hemoproteinas. - Google Patents

Proceso de produccion de hemoproteinas.

Info

Publication number
ES2134844T3
ES2134844T3 ES93907815T ES93907815T ES2134844T3 ES 2134844 T3 ES2134844 T3 ES 2134844T3 ES 93907815 T ES93907815 T ES 93907815T ES 93907815 T ES93907815 T ES 93907815T ES 2134844 T3 ES2134844 T3 ES 2134844T3
Authority
ES
Spain
Prior art keywords
heme
production process
production
hemoprotein
hemoprotein production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93907815T
Other languages
English (en)
Inventor
Ejner Bech Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2134844T3 publication Critical patent/ES2134844T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN PROCESO PARA LA PRODUCCION DE UNA PROTEINA HEME EXTRACELULAR EN GRANDES CANTIDADES, CUYO PROCESO CONSISTE EN CULTIVAR UN MICROORGANISMO QUE PRODUZCA APOPROTEINAS EN UN MEDIO DE FERMENTACION QUE CONTENGA HEME O UN MATERIAL QUE CONTENGA HEME BAJO CONDICIONES QUE PERMITAN LA PRODUCCION DE UNA PROTEINA HEME RECOMBINADA, ACTIVA Y SEPARAR LA PROTEINA HEME RESULTANTE DEL MEDIO DE CULTIVO.
ES93907815T 1992-03-20 1993-03-16 Proceso de produccion de hemoproteinas. Expired - Lifetime ES2134844T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92365A DK36592D0 (da) 1992-03-20 1992-03-20 Fremgangsmaade til fremstilling af proteiner

Publications (1)

Publication Number Publication Date
ES2134844T3 true ES2134844T3 (es) 1999-10-16

Family

ID=8092696

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93907815T Expired - Lifetime ES2134844T3 (es) 1992-03-20 1993-03-16 Proceso de produccion de hemoproteinas.

Country Status (9)

Country Link
US (1) US5681725A (es)
EP (1) EP0631631B1 (es)
JP (1) JP3330941B2 (es)
AT (1) ATE180837T1 (es)
CA (1) CA2132299A1 (es)
DE (1) DE69325169T2 (es)
DK (2) DK36592D0 (es)
ES (1) ES2134844T3 (es)
WO (1) WO1993019195A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO776697A0 (en) * 1997-07-08 1997-07-31 Commonwealth Scientific And Industrial Research Organisation Method of increasing the iron content of plant cells
JP2001523460A (ja) 1997-11-17 2001-11-27 ノボ ノルディスク バイオテック，インコーポレイティド ウロポルフィリノーゲンデカルボキシラーゼ活性を有するポリペプチド及びそれをコードする核酸
US6033892A (en) 1998-11-16 2000-03-07 Novo Nordis Biotech, Inc. Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same
CN1152136C (zh) * 1997-11-17 2004-06-02 诺沃奇梅兹生物技术有限公司 具有5-氨基酮戊酸合酶活性的多肽和编码该多肽的核酸
JP2001526037A (ja) * 1997-12-08 2001-12-18 ノボザイムス バイオテック，インコーポレイティド 真菌変異体においてヘムタンパク質生産を増加させるための方法
KR102168039B1 (ko) 2017-12-12 2020-10-21 한국과학기술원 대사공학적으로 조작된 미생물을 이용한 헴의 세포외 생산방법
WO2019117612A1 (ko) 2017-12-12 2019-06-20 한국과학기술원 대사공학적으로 조작된 미생물을 이용한 헴의 세포외 생산방법
CN108251441A (zh) * 2017-12-28 2018-07-06 广州天宝颂原生物科技开发有限公司 一种链亲和素融合光敏色素的荧光标记物的制备方法
KR102780646B1 (ko) 2021-05-10 2025-03-17 한국과학기술원 풍미, 영양 및 색감이 개선된 식품 및 이의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340668A (en) * 1979-06-04 1982-07-20 Miles Laboratories, Inc. Heme-labeled specific binding assay
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
NZ217373A (en) * 1985-08-29 1990-10-26 Genencor Inc Production of heterologous peptide in filamentous fungi, vectors and dna
NZ242074A (en) * 1991-03-22 1993-08-26 Novo Nordisk As Extracellular production of a heterologous heme protein in a filamentous fungus; dna construct therefor

Also Published As

Publication number Publication date
DK36592D0 (da) 1992-03-20
ATE180837T1 (de) 1999-06-15
DE69325169T2 (de) 1999-12-30
EP0631631A1 (en) 1995-01-04
JPH07504572A (ja) 1995-05-25
WO1993019195A1 (en) 1993-09-30
JP3330941B2 (ja) 2002-10-07
EP0631631B1 (en) 1999-06-02
DK0631631T3 (da) 1999-11-29
CA2132299A1 (en) 1993-09-30
US5681725A (en) 1997-10-28
DE69325169D1 (de) 1999-07-08

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