ES2134925T3 - Procedimiento para la transformacion estable de trigo. - Google Patents

Procedimiento para la transformacion estable de trigo.

Info

Publication number
ES2134925T3
ES2134925T3 ES94903608T ES94903608T ES2134925T3 ES 2134925 T3 ES2134925 T3 ES 2134925T3 ES 94903608 T ES94903608 T ES 94903608T ES 94903608 T ES94903608 T ES 94903608T ES 2134925 T3 ES2134925 T3 ES 2134925T3
Authority
ES
Spain
Prior art keywords
wheat
procedure
transformed
stable transformation
fertile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94903608T
Other languages
English (en)
Other versions
ES2134925T5 (es
Inventor
Yin-Fu Chang
James Richard Wong
Andrea Itano
Stephen J Mejza
Leslie Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26844765&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2134925(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of ES2134925T3 publication Critical patent/ES2134925T3/es
Application granted granted Critical
Publication of ES2134925T5 publication Critical patent/ES2134925T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8206—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated
    • C12N15/8207—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cereal-Derived Products (AREA)
  • Noodles (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)

Abstract

Método para producir plantas de trigo fértiles transformadas de manera estable, comprendiendo dicho método: (a) escindir un embrión inmaduro de una planta de trigo; (b) preparar una placa Petri de dicho embrión inmaduro escindido en un medio de crecimiento; (c) bombardear dicho embrión inmaduro escindido y en la placa Petri con una secuencia de DNA de interés de 0 a 10 días después de la escisión; (d) mantener el embión o callus en desarrollo durante 1 a 10 semanas en la oscuridad en medio de crecimiento con o sin presión de selección; (e) regenerar a partir del mismo plantas transformadas fértiles en presencia de selección.
ES94903608T 1992-12-16 1993-12-13 Metodos para la transformacion estable de trigo. Expired - Lifetime ES2134925T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99239192A 1992-12-16 1992-12-16
US992391 1992-12-16
US08/147,261 US5610042A (en) 1991-10-07 1993-11-01 Methods for stable transformation of wheat
US147261 1993-11-01

Publications (2)

Publication Number Publication Date
ES2134925T3 true ES2134925T3 (es) 1999-10-16
ES2134925T5 ES2134925T5 (es) 2007-06-01

Family

ID=26844765

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94903608T Expired - Lifetime ES2134925T5 (es) 1992-12-16 1993-12-13 Metodos para la transformacion estable de trigo.

Country Status (10)

Country Link
US (2) US5610042A (es)
EP (1) EP0674715B2 (es)
AT (1) ATE181364T1 (es)
AU (1) AU688297B2 (es)
CA (1) CA2151127C (es)
DE (1) DE69325389T3 (es)
DK (1) DK0674715T4 (es)
ES (1) ES2134925T5 (es)
GR (1) GR3031054T3 (es)
WO (1) WO1994013822A2 (es)

Families Citing this family (263)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605712B1 (en) * 1990-12-20 2003-08-12 Arch Development Corporation Gene transcription and ionizing radiation: methods and compositions
US5610042A (en) * 1991-10-07 1997-03-11 Ciba-Geigy Corporation Methods for stable transformation of wheat
US7262055B2 (en) 1998-08-25 2007-08-28 Gendaq Limited Regulated gene expression in plants
US7285416B2 (en) 2000-01-24 2007-10-23 Gendaq Limited Regulated gene expression in plants
US5631152A (en) * 1994-10-26 1997-05-20 Monsanto Company Rapid and efficient regeneration of transgenic plants
HUP9902123A3 (en) 1996-06-21 2002-01-28 Monsanto Technology Llc St Louis Methods for the production of stably-transformed, fertile wheat employing agrobacterium-mediated transformation
US5773269A (en) * 1996-07-26 1998-06-30 Regents Of The University Of Minnesota Fertile transgenic oat plants
US6002068A (en) * 1996-12-19 1999-12-14 Novartis Finance Corporation Methods for conferring insect resistance to a monocot using a perioxidase coding sequence
US6872871B2 (en) * 1998-02-02 2005-03-29 Odyssey Thera Inc. Mapping molecular interactions in plants with protein fragments complementation assays
US7102056B1 (en) 1997-04-29 2006-09-05 The Regents Of The University Of California Compositions and methods for plant transformation and regeneration
US6235529B1 (en) * 1997-04-29 2001-05-22 The Regents Of The University Of California Compositions and methods for plant transformation and regeneration
MX257801B (en) 1997-06-02 2008-06-10 Syngenta Participations Ag Plant transformation methods
EP1017268A1 (en) 1997-09-24 2000-07-12 The Regents Of The University Of California Methods and compositions for transformation of cereals using cultured shoot meristematic tissue
EP1019517B2 (en) 1997-09-30 2014-05-21 The Regents of The University of California Production of proteins in plant seeds
US6060315A (en) * 1997-12-01 2000-05-09 Lockheed Martin Energy Research Corporation Method for facilitating the introduction of material into cells
US6153811A (en) 1997-12-22 2000-11-28 Dekalb Genetics Corporation Method for reduction of transgene copy number
CN1206360C (zh) 1998-02-20 2005-06-15 辛甄塔有限公司 杂交种子生产
US5973227A (en) * 1998-05-06 1999-10-26 University Of Saskatchewan Flax transformation
US7897843B2 (en) 1999-03-23 2011-03-01 Mendel Biotechnology, Inc. Transcriptional regulation of plant biomass and abiotic stress tolerance
US20050086718A1 (en) 1999-03-23 2005-04-21 Mendel Biotechnology, Inc. Plant transcriptional regulators of abiotic stress
AU782918B2 (en) 1999-11-10 2005-09-08 University Of Washington Compositions and methods for modulation of plant cell division
EP1950306A1 (en) 1999-11-17 2008-07-30 Mendel Biotechnology, Inc. Environmental stress tolerance genes
MXPA02004878A (es) 1999-11-17 2004-04-05 Mendel Biotechnology Inc Genes relacionados con la bioquimica de la planta.
US6812028B1 (en) * 1999-12-10 2004-11-02 University Of Guelph Embryogenesis and plant regeneration from microspores
US6750379B2 (en) * 2000-03-09 2004-06-15 Dekalb Genetics Corporation Homologous recombination-mediated transgene alterations in plants
US6580019B1 (en) 2000-03-09 2003-06-17 Dekalb Genetics Corporation Non-reciprocal recombination-mediated transgene deletion in transgenic plants
US6806399B1 (en) * 2000-04-19 2004-10-19 Carmel-Haifa University Economic Corporation Ltd. Pollen-mediated method for transformation of maize, tomato or melon
US7468475B2 (en) 2000-06-16 2008-12-23 Schmuelling Thomas Method for modifying plant morphology, biochemistry and physiology
US6995016B2 (en) 2000-08-17 2006-02-07 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Process for inducing direct somatic embryogenesis in immature scutella cells of pooideae, and rapidly regenerating fertile plants
EP1406483A4 (en) 2000-08-22 2005-05-25 Mendel Biotechnology Inc GENE FOR CHANGING THE PROPERTIES OF PLANTS
FR2815969B1 (fr) 2000-10-30 2004-12-10 Aventis Cropscience Sa Plantes tolerantes aux herbicides par contournement de voie metabolique
AU2002236234B2 (en) 2001-03-06 2007-12-20 Phyton Holdings, LLC. Plant cell having animal-type sugar chain adding function
AU2002306764A1 (en) * 2001-03-19 2002-10-03 Cargill Incorporated Myo-inositol oxygenases
US20040242523A1 (en) * 2003-03-06 2004-12-02 Ana-Farber Cancer Institue And The Univiersity Of Chicago Chemo-inducible cancer gene therapy
ES2380007T3 (es) * 2001-04-06 2012-05-07 The University Of Chicago Inducción por agentes quimioterapéuticos de la actividad del promotor Egr-1 en la terapia génica
US8034791B2 (en) 2001-04-06 2011-10-11 The University Of Chicago Activation of Egr-1 promoter by DNA damaging chemotherapeutics
JP4338402B2 (ja) 2001-05-22 2009-10-07 ユニバーシティ オブ シカゴ Ｎ４ウイルス一本鎖ｄｎａ依存的ｒｎａポリメラーゼ
WO2002096923A1 (en) 2001-05-30 2002-12-05 Chromos Molecular Systems, Inc. Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes
AR037038A1 (es) * 2001-10-26 2004-10-20 Baylor College Medicine Una composicion y metodo para alterar la masa corporal magra y las propiedades oseas en un sujeto
AU2002357143B2 (en) * 2001-12-11 2009-07-30 Advisys, Inc. Growth hormone releasing hormone supplementation for treating chronically ill subjects
EP2213737B1 (en) * 2002-02-01 2012-11-07 Life Technologies Corporation Double-stranded oligonucleotides
US20030166282A1 (en) * 2002-02-01 2003-09-04 David Brown High potency siRNAS for reducing the expression of target genes
US20060009409A1 (en) * 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
US7622632B2 (en) 2002-05-22 2009-11-24 Monsanto Technology Llc Fatty acid desaturases from fungi
US20040248094A1 (en) * 2002-06-12 2004-12-09 Ford Lance P. Methods and compositions relating to labeled RNA molecules that reduce gene expression
AU2003247582A1 (en) 2002-06-20 2004-01-06 Board Of Trustees Operating Michigan State University Plastid division and related genes and proteins, and methods of use
US6916474B2 (en) 2002-07-15 2005-07-12 Board Of Regents, The University Of Texas System Antibodies with increased affinities for anthrax antigens
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
US20040029275A1 (en) * 2002-08-10 2004-02-12 David Brown Methods and compositions for reducing target gene expression using cocktails of siRNAs or constructs expressing siRNAs
EP2269619A1 (en) 2002-08-12 2011-01-05 Jennerex Biotherapeutics ULC Methods and compositions concerning poxviruses and cancer
US7429691B2 (en) * 2002-09-03 2008-09-30 The Regents Of The University Of California Methods and compositions for transformation and regeneration of maize
DK1546336T3 (da) 2002-09-18 2012-04-10 Mendel Biotechnology Inc Polynukleotider og polypeptider i planter.
CA2516320C (en) 2003-02-18 2015-05-26 Kevin Slawin Induced activation in dendritic cells
TW200424214A (en) * 2003-04-21 2004-11-16 Advisys Inc Plasmid mediated GHRH supplementation for renal failures
US7655833B2 (en) 2003-05-29 2010-02-02 Brookhaven Science Associates, Llc ADS genes for reducing saturated fatty acid levels in seed oils
US7812221B2 (en) 2003-06-30 2010-10-12 Commonwealth Scientific And Industrial Research Organization Wheat with altered branching enzyme activity and starch and starch containing products derived therefrom
EP1788861B1 (en) 2004-08-24 2017-04-12 Monsanto Technology, LLC Adenylate translocator protein gene non-coding regulatory elements for use in plants
CN101107362A (zh) 2004-10-21 2008-01-16 文甘扎公司 用于赋予对植物病害生物和植物病原体抗性的方法和材料
CA2857881A1 (en) 2004-11-12 2006-12-28 Asuragen, Inc. Methods and compositions involving mirna and mirna inhibitor molecules
CN100362104C (zh) 2004-12-21 2008-01-16 华中农业大学 利用水稻转录因子基因OsNACx提高植物抗旱耐盐能力
AR053269A1 (es) 2005-05-16 2007-04-25 Monsanto Technology Llc Plantas y semillas de maiz con mejoramiento de asparagina y proteina
WO2006125065A2 (en) 2005-05-18 2006-11-23 The Board Of Trustees Operating Michigan State University Resistance to soybean aphid in early maturing soybean germplasm
RU2421462C2 (ru) 2005-07-29 2011-06-20 Таргитид Гроус, Инк. Защитное действие доминантно-негативного мутантного белка krp от ингибирования активного комплекса циклин-cdk krp дикого типа
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
KR101772375B1 (ko) * 2005-09-07 2017-08-29 신라젠(주) Ｇｍ-ｃｓｆ를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법
WO2007030674A2 (en) * 2005-09-07 2007-03-15 Maxcyte, Inc. Use of nucleases to improve viability and enhance transgene expression in transfected cells
RU2431249C2 (ru) 2005-12-15 2011-10-20 Таргитид Гроус, Инк. Способ увеличения размера семян и числа семян в растении в результате трансгенной сверхэкспрессии гена, связанного с ростом и/или развитием, в период раннего зародышевого развития
US7663020B2 (en) * 2006-01-11 2010-02-16 Agrinomics Llc Generation of plants with altered oil content
US20090317421A1 (en) 2006-01-18 2009-12-24 Dominique Missiakas Compositions and methods related to staphylococcal bacterium proteins
US7868228B2 (en) 2006-01-31 2011-01-11 Monsanto Technology Llc Phosphopantetheinyl transferases from bacteria
US7820883B2 (en) 2006-03-15 2010-10-26 Dow Agrosciences Llc Resistance to auxinic herbicides
US8304239B2 (en) 2006-03-31 2012-11-06 Reliance Life Sciences Pvt Ltd. Direct regeneration of plantlets in Jatropha curcas
US7977535B2 (en) 2006-07-12 2011-07-12 Board Of Trustees Of Michigan State University DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants
AU2007278864A1 (en) 2006-07-27 2008-01-31 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Cellular receptor for antiproliferative factor
CA2663034C (en) 2006-09-15 2016-05-03 Ottawa Health Research Institute Oncolytic rhabdovirus
CA2667396C (en) 2006-09-25 2017-03-28 Freie Universitaet Berlin Transcriptional repressors of cytokinin signaling and their use
CA2666667C (en) 2006-10-19 2023-06-20 Baylor College Of Medicine Generating an immune response by inducing cd40 and pattern recognition receptors
MX2009004221A (es) 2006-10-20 2009-09-10 Univ Arizona State Cianobacterias modificadas.
US8106253B2 (en) 2006-11-15 2012-01-31 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
US7763771B2 (en) * 2006-11-15 2010-07-27 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
US8034993B2 (en) * 2006-11-15 2011-10-11 Dow Agrosciences Llc Generation of plants with altered protein, fiber, or oil content
WO2008061156A2 (en) 2006-11-15 2008-05-22 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
CA2988382A1 (en) * 2006-11-15 2008-05-22 Agrigenetics, Inc. Generation of plants with altered protein, fiber, or oil content
WO2008067547A2 (en) 2006-11-30 2008-06-05 Research Development Foundation Improved immunoglobulin libraries
WO2008076834A2 (en) * 2006-12-15 2008-06-26 Agrinomics Llc Generation of plants with altered oil, protein, or fiber content
US7790954B2 (en) * 2006-12-15 2010-09-07 Agrigenetics, Inc. Generation of plants with altered oil, protein, or fiber content
EP2120531A4 (en) * 2006-12-15 2010-08-25 Agrinomics Llc GENERATION OF PLANTS WITH CHANGED OIL, PROTEIN OR FIBER CONTENT
MX2009006465A (es) * 2006-12-15 2009-08-21 Agrinomics Llc Generacion de plantas con contenido de aceite, proteina o fibra alterado.
EP2120532A4 (en) * 2006-12-15 2010-08-11 Agrinomics Llc PRODUCTION OF PLANTS WITH A CONTENT MODIFIED IN OIL, PROTEIN OR FIBER
KR20080084528A (ko) 2007-03-15 2008-09-19 제네렉스 바이오테라퓨틱스 인크. 종양살상형 백시니아 바이러스 암 치료
AU2008247819B2 (en) 2007-05-01 2013-02-14 Research Development Foundation Immunoglobulin Fc libraries
WO2008157559A2 (en) * 2007-06-18 2008-12-24 Agrinomics Llc Generation of plants with altered oil, protein or fiber content
EP2185190B1 (en) 2007-08-31 2015-06-24 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
CA2711499C (en) 2008-01-10 2018-09-25 Research Development Foundation Vaccines and diagnostics for the ehrlichioses
MX2010008168A (es) 2008-01-25 2011-02-24 P53 Inc Biomarcadores p53.
EP3279314A1 (en) 2008-06-04 2018-02-07 Cellular Dynamics International, Inc. Methods for the production of ips cells using non-viral approach
JP2012500005A (ja) 2008-08-12 2012-01-05 セルラー ダイナミクス インターナショナル， インコーポレイテッド ｉＰＳ細胞を生成するための方法
EP2328603A4 (en) 2008-08-18 2013-01-02 Univ Maryland APF DERIVATIVES AND USE METHOD
EP2331680B1 (en) * 2008-09-22 2017-05-03 Baylor College Of Medicine Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
EP2341929B1 (en) 2008-10-06 2017-01-25 University Of Chicago Compositions and methods related to bacterial emp proteins
WO2010045324A1 (en) 2008-10-14 2010-04-22 Monsanto Technology Llc Utilization of fatty acid desaturases from hemiselmis spp.
US9133475B2 (en) 2008-11-26 2015-09-15 Board Of Trustees Of Michigan State University Aphid resistant soybean plants
EP2370568B1 (en) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
US8362318B2 (en) 2008-12-18 2013-01-29 Board Of Trustees Of Michigan State University Enzyme directed oil biosynthesis in microalgae
JP2012515532A (ja) 2009-01-20 2012-07-12 ラモット アット テル アビブ ユニバーシティ， リミテッド Ｍｉｒ−２１プロモーター駆動性標的がん治療
US20120058523A1 (en) 2009-02-17 2012-03-08 Edenspace Systems Corporation Tempering of cellulosic biomass
ES2784957T3 (es) 2009-04-03 2020-10-02 Univ Chicago Composiciones y métodos relacionados con variantes de la proteína A (SPA)
DK3061766T3 (da) 2009-04-28 2020-03-16 Univ Vanderbilt Sammensætninger og fremgangsmåder til behandlingen af sygdomme der involverer epitelcelleapoptose
US20120079627A1 (en) 2009-05-29 2012-03-29 Edenspace Systems Corporation Plant gene regulatory elements
DK2438160T3 (en) 2009-06-05 2016-01-11 Cellular Dynamics Int Inc Reprogramming of T cells and hematopoietic cells
CA2772298A1 (en) 2009-08-26 2011-03-03 Research Development Foundation Methods for creating antibody libraries
BR112012005774B8 (pt) 2009-09-14 2023-02-14 Jennerex Inc uso de um inibidor de quinase antiangiogênico no tratamento de câncer
WO2011050271A1 (en) 2009-10-23 2011-04-28 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
CA2836117C (en) 2009-12-10 2017-08-15 Ottawa Hospital Research Institute Oncolytic rhabdovirus
US9328335B2 (en) 2009-12-30 2016-05-03 Board Of Trustees Of Michigan State University Method to produce acetyldiacylglycerols (ac-TAGs) by expression of an acetyltransferase gene isolated from Euonymus alatus (burning bush)
US10080799B2 (en) 2010-02-12 2018-09-25 Arizona Board Of Regents On Behalf Of Arizona State University Methods and compositions related to glycoprotein-immunoglobulin fusions
EP3028699B1 (en) 2010-02-25 2018-03-21 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
ES2631458T3 (es) 2010-03-04 2017-08-31 Interna Technologies B.V. Molécula de ARNmi definida por su fuente y sus usos terapéuticos en el cáncer asociado a la EMT
JP2013523818A (ja) 2010-04-05 2013-06-17 ザ・ユニバーシティー・オブ・シカゴ 免疫反応のエンハンサーとしてのプロテインＡ（ＳｐＡ）抗体に関連する組成物および方法
WO2011126976A1 (en) 2010-04-07 2011-10-13 Vanderbilt University Reovirus vaccines and methods of use therefor
DK2560672T3 (en) 2010-04-19 2014-03-17 Res Dev Foundation RTEF-1 variants and their uses
CA2799614A1 (en) 2010-05-19 2011-11-24 The Samuel Roberts Noble Foundation, Inc. Altered leaf morphology and enhanced agronomic properties in plants
WO2011146862A1 (en) 2010-05-21 2011-11-24 Bellicum Pharmaceuticals, Inc. Methods for inducing selective apoptosis
JP5908466B2 (ja) 2010-06-09 2016-04-26 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｒａｆ及びｍｅｋ阻害剤に対する耐性を与えるｍｅｋ１変異
CA2802087A1 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
JP5984217B2 (ja) 2010-06-15 2016-09-06 セルラー ダイナミクス インターナショナル， インコーポレイテッド 少量の末梢血からの人工多能性幹細胞の作製
JP6002128B2 (ja) 2010-07-02 2016-10-05 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ プロテインＡ（ＳｐＡ）変種に関連する組成物および方法
NZ704322A (en) 2010-07-06 2016-07-29 Interna Technologies Bv Mirna and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated braf pathway
WO2012006440A2 (en) 2010-07-07 2012-01-12 Cellular Dynamics International, Inc. Endothelial cell production by programming
WO2012018933A2 (en) 2010-08-04 2012-02-09 Cellular Dynamics International, Inc. Reprogramming immortalized b cells
US9095540B2 (en) 2010-09-09 2015-08-04 The University Of Chicago Methods and compositions involving protective staphylococcal antigens
EP3536337A1 (en) 2010-09-22 2019-09-11 The Regents of the University of Colorado, a body corporate Therapeutic applications of smad7
US9045549B2 (en) 2010-11-03 2015-06-02 The Samuel Roberts Noble Foundation, Inc. Transcription factors for modification of lignin content in plants
KR101942237B1 (ko) 2011-01-04 2019-01-25 신라젠(주) 종양 항원에 대한 항체의 생산 및 종양용해 우두 바이러스의 투여에 의한 종양 특이적 보체 의존적 세포독성의 생산
EP2474617A1 (en) 2011-01-11 2012-07-11 InteRNA Technologies BV Mir for treating neo-angiogenesis
AU2012214643B2 (en) 2011-02-07 2016-12-15 Research Development Foundation Engineered immunoglobulin Fc polypeptides
WO2012109208A2 (en) 2011-02-08 2012-08-16 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
US9085631B2 (en) 2011-04-08 2015-07-21 Nov Vac APS Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
US8901371B2 (en) 2011-05-06 2014-12-02 The Samuel Roberts Noble Foundation, Inc. Compositions and methods for improved plant feedstock
WO2012170304A2 (en) 2011-06-02 2012-12-13 The Regents Of The University Of California Plants with elevated levels of glucan
CA2872045A1 (en) 2011-06-08 2012-12-13 Children's Hospital Of Eastern Ontario Research Institute Inc. Compositions and methods for glioblastoma treatment
WO2013005211A2 (en) 2011-07-05 2013-01-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Boron complexing plant materials and uses thereof cross-reference to related applications
WO2013009825A1 (en) 2011-07-11 2013-01-17 Cellular Dynamics International, Inc. Methods for cell reprogramming and genome engineering
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
WO2013026015A1 (en) 2011-08-18 2013-02-21 Dana-Farber Cancer Institute, Inc. Muc1 ligand traps for use in treating cancers
WO2013053899A1 (en) 2011-10-12 2013-04-18 Moeller Niels Iversen Peptides derived from campylobacter jejuni and their use in vaccination
ES2886147T3 (es) 2011-12-22 2021-12-16 Interna Tech B V MiARN para el tratamiento del cáncer de cabeza y de cuello
AU2013252883B2 (en) 2012-04-26 2018-05-17 University Of Chicago Staphylococcal coagulase antigens and methods of their use
EP2841101B1 (en) 2012-04-26 2019-08-07 University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease
PT2880167T (pt) 2012-07-31 2018-07-23 Univ Texas Métodos e composições para a indução in vivo da formação de células beta pancreáticas
ES2763413T3 (es) 2012-09-24 2020-05-28 Seminis Vegetable Seeds Inc Procedimientos y composiciones para prolongar la vida útil de productos vegetales
CA2887825A1 (en) 2012-10-23 2014-05-01 The Board Of Regents Of The University Of Texas System Engineered igg fc domains
US10201556B2 (en) 2012-11-06 2019-02-12 Interna Technologies B.V. Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated B-raf pathway
CA2836403A1 (en) 2013-01-04 2014-07-04 Board Of Trustees Of Michigan State University New sources of aphid resistance in soybean plants
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
CA2901501C (en) 2013-02-21 2023-03-07 Children's Hospital Of Eastern Ontario Research Institute Inc. Vaccine composition
CN105229144A (zh) 2013-02-22 2016-01-06 细胞动力学国际有限公司 通过组合的遗传工程和化学工程经由正向编程产生肝细胞
US10086093B2 (en) 2013-02-28 2018-10-02 The General Hospital Corporation miRNA profiling compositions and methods of use
WO2014132137A2 (en) 2013-03-01 2014-09-04 Université De Genève Transgenic cell selection
CN105358704B (zh) 2013-03-08 2020-01-03 科罗拉多大学董事会 Ptd-smad7治疗剂
US9434935B2 (en) 2013-03-10 2016-09-06 Bellicum Pharmaceuticals, Inc. Modified caspase polypeptides and uses thereof
WO2014151960A2 (en) 2013-03-14 2014-09-25 Bellicum Pharmaceuticals, Inc. Methods for controlling t cell proliferation
CA2912172A1 (en) 2013-06-05 2014-12-11 Bellicum Pharmaceuticals, Inc. Methods for inducing partial apoptosis using caspase polypeptides
EP3043825A4 (en) 2013-09-09 2017-05-03 Figene, LLC Gene therapy for the regeneration of chondrocytes or cartilage type cells
EP3065706A4 (en) 2013-11-08 2017-11-29 Baylor Research Institute Nuclear localization of glp-1 stimulates myocardial regeneration and reverses heart failure
CA2965327C (en) 2013-11-08 2023-05-09 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
ES3012932T3 (en) 2013-12-03 2025-04-10 Evaxion Biotech As Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
US10392629B2 (en) 2014-01-17 2019-08-27 Board Of Trustees Of Michigan State University Increased caloric and nutritional content of plant biomass
US10059775B2 (en) 2014-01-29 2018-08-28 Dana-Farber Cancer Institute, Inc. Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
US10214741B2 (en) 2014-02-14 2019-02-26 University Of Utah Research Foundation Methods and compositions for inhibiting retinopathy of prematurity
US10934346B2 (en) 2014-02-14 2021-03-02 Bellicum Pharmaceuticals, Inc. Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
WO2015130783A1 (en) 2014-02-25 2015-09-03 Research Development Foundation Sty peptides for inhibition of angiogenesis
US9307708B2 (en) 2014-03-07 2016-04-12 Pioneer Hi-Bred International Inc Systems for extracting monocot embryos
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
AR100874A1 (es) 2014-06-16 2016-11-09 Consejo Nac De Investig Científicas Y Técnicas (Conicet) Genes quiméricos y proteínas de resistencia oxidativa, y plantas transgénicas que incluyen los mismos
US10888608B2 (en) 2014-09-02 2021-01-12 Bellicum Pharmaceuticals, Inc. Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides
WO2016039961A1 (en) 2014-09-11 2016-03-17 Marrone Bio Innovations, Inc Chromobacterium subtsugae genome
ES2904301T3 (es) 2014-11-03 2022-04-04 Academisch Ziekenhuis Leiden H O D N Leids Univ Medisch Centrum Receptores de células T dirigidos contra Bob1 y usos de los mismos
WO2016077624A1 (en) 2014-11-12 2016-05-19 Nmc, Inc. Transgenic plants with engineered redox sensitive modulation of photosynthetic antenna complex pigments and methods for making the same
US20180169211A1 (en) 2014-11-13 2018-06-21 Evaxion Biotech Aps Peptides derived from acinetobacter baumannii and their use in vaccination
HK1245827B (en) 2014-12-15 2020-06-19 Board Of Regents Of The University Of Texas System Methods for controlled activation or elimination of therapeutic cells
WO2016113252A2 (en) 2015-01-12 2016-07-21 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting klebsiella pneumoniae
EP3250675A1 (en) 2015-01-28 2017-12-06 SABIC Global Technologies B.V. Methods and compositions for high-efficiency production of biofuel and/or biomass
JP6724023B2 (ja) 2015-02-09 2020-07-15 リサーチ ディベロップメント ファウンデーション 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド
EP3259346B1 (en) 2015-02-20 2024-08-07 Baylor College of Medicine P63 inactivation for the treatment of heart failure
JP2018510627A (ja) 2015-03-10 2018-04-19 レイデン ユニバーシティ メディカル センター メラノーマ優先発現抗原に対して向けられたｔ細胞レセプターおよびその使用
EP3317295B1 (en) 2015-07-04 2022-05-18 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
CN108431211B (zh) 2015-10-20 2026-03-24 富士胶片细胞动力公司 通过遗传编程的多谱系造血前体细胞产生
MX2018005274A (es) 2015-10-30 2019-09-19 The Regents Of The Universtiy Of California Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
EP3370733B1 (en) 2015-11-02 2021-07-14 Board of Regents, The University of Texas System Methods of cd40 activation and immune checkpoint blockade
US20190038713A1 (en) 2015-11-07 2019-02-07 Multivir Inc. Compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
JP6987068B2 (ja) 2015-11-09 2021-12-22 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia 癌マーカーおよび治療標的としてのグリピカン２
EP3419654B1 (en) 2016-02-22 2022-04-27 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
WO2017168348A1 (en) 2016-03-31 2017-10-05 Baylor Research Institute Angiopoietin-like protein 8 (angptl8)
WO2017216384A1 (en) 2016-06-17 2017-12-21 Evaxion Biotech Aps Vaccination targeting ichthyophthirius multifiliis
WO2017220787A1 (en) 2016-06-24 2017-12-28 Evaxion Biotech Aps Vaccines against aearomonas salmonicida infection
EP3478325B1 (en) 2016-07-01 2024-07-17 Research Development Foundation Elimination of proliferating cells from stem cell-derived grafts
US11414464B2 (en) 2016-07-22 2022-08-16 Evaxion Biotech A/S Chimeric proteins for inducing immunity towards infection with S. aureus
US9963498B2 (en) 2016-08-18 2018-05-08 Wisconsin Alumni Research Foundation Peptides that inhibit syndecan-1 activation of VLA-4 and IGF-1R
CA3034739A1 (en) 2016-08-22 2018-03-01 Biolumic Limited System, device and methods of seed treatment
JP2019530440A (ja) 2016-09-02 2019-10-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インターロイキン６受容体α結合単鎖可変断片を含む方法および組成物
EP3523422B1 (en) 2016-10-05 2024-12-25 FUJIFILM Cellular Dynamics, Inc. Generating mature lineages from induced pluripotent stem cells with mecp2 disruption
JP7212615B2 (ja) 2016-10-05 2023-01-25 フジフィルム セルラー ダイナミクス，インコーポレイテッド 多能性幹細胞からｈｌａホモ接合免疫細胞への指向分化方法
RU2646108C1 (ru) * 2016-12-07 2018-03-01 Федеральное государственное бюджетное учреждение науки Институт биологии развития им. Н.К. Кольцова РАН Способ получения трансгенных растений пшеницы с использованием биобаллистики
WO2018111902A1 (en) 2016-12-12 2018-06-21 Multivir Inc. Methods and compositions comprising viral gene therapy and an immune checkpoint inhibitor for treatment and prevention of cancer and infectious diseases
US11718648B2 (en) 2017-01-05 2023-08-08 Evaxion Biotech A/S Vaccines targeting Pseudomonas aeruginosa
CA3055389A1 (en) 2017-03-07 2018-09-13 BASF Agricultural Solutions Seed US LLC Hppd variants and methods of use
BR112019018059A2 (pt) 2017-03-07 2020-08-04 BASF Agricultural Solutions Seed US LLC molécula de ácido nucleico recombinante, célula hospedeira, plantas, sementes transgênicas, polipeptídeo recombinante, método para produzir um polipeptídeo, método de controle de ervas daninhas, uso do ácido nucleico e produto de utilidade
WO2018195175A1 (en) 2017-04-18 2018-10-25 FUJIFILM Cellular Dynamics, Inc. Antigen-specific immune effector cells
WO2018208849A1 (en) 2017-05-09 2018-11-15 Bellicum Pharmaceuticals, Inc. Methods to augment or alter signal transduction
WO2018213679A1 (en) 2017-05-19 2018-11-22 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
WO2019002946A1 (en) 2017-06-29 2019-01-03 Biolumic Limited METHOD OF ENHANCING YIELD AND / OR CULTURE QUALITY
WO2019038594A2 (en) 2017-08-21 2019-02-28 Biolumic Limited TRANSGENIC PLANTS WITH HIGH GROWTH AND HIGH RUSTICITY
US11497762B2 (en) 2017-11-03 2022-11-15 Interna Technologies B.V. MiRNA molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation
WO2019090261A1 (en) 2017-11-03 2019-05-09 University Of Florida Research Foundation, Inc. Methods and compositions for plant pathogen resistance in plants
EP3710014A1 (en) 2017-11-14 2020-09-23 Henry Ford Health System Compositions for use in the treatment and prevention of cardiovascular disorders resulting from cerebrovascular injury
BR112020013715A2 (pt) 2018-01-05 2020-12-01 Ottawa Hospital Research Institute vetores de vaccinia modificados
WO2019145399A1 (en) 2018-01-24 2019-08-01 Evaxion Biotech Aps Vaccines for prophylaxis of s. aureus infections
EP3768698B1 (en) 2018-03-19 2025-02-12 MultiVir Inc. Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer
SG11202009697RA (en) 2018-03-30 2020-10-29 Univ Geneve Micro rna expression constructs and uses thereof
WO2020069313A2 (en) 2018-09-28 2020-04-02 Henry Ford Health System Use of extracellular vesicles in combination with tissue plasminogen activator and/or thrombectomy to treat stroke
EP3870207A1 (en) 2018-10-22 2021-09-01 Evaxion Biotech ApS Vaccines targeting m. catharrhalis
WO2020171889A1 (en) 2019-02-19 2020-08-27 University Of Rochester Blocking lipid accumulation or inflammation in thyroid eye disease
WO2020174044A1 (en) 2019-02-27 2020-09-03 Evaxion Biotech Aps Vaccines targeting h. influenzae
WO2020212756A2 (en) 2019-04-18 2020-10-22 Genkin Dmitry Dmitrievich Reprogramming of polymorphonuclear leukocytes
MX2021013833A (es) 2019-05-14 2022-03-17 Univ Chicago Metodos y composiciones que comprenden variantes de la proteina a de estafilococos (spa).
CN120484131A (zh) 2019-07-19 2025-08-15 费城儿童医院 包含磷脂酰肌醇蛋白聚糖2结合结构域的嵌合抗原受体
TW202128160A (zh) 2019-10-18 2021-08-01 美國加利福尼亞大學董事會 用於治療病原性血管病症之方法及組合物
WO2021113644A1 (en) 2019-12-05 2021-06-10 Multivir Inc. Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
EP4087593A1 (en) 2020-01-06 2022-11-16 Evaxion Biotech A/S Vaccines targeting neisseria gonorrhoeae
IL298558A (en) 2020-05-27 2023-01-01 Antion Biosciences Sa Adapter molecules redirect CAR T cells to the antigen of interest
CA3180561A1 (en) 2020-05-29 2021-12-02 Andrew DIAS Bilayer of retinal pigmented epithelium and photoreceptors and use thereof
BR112022024031A2 (pt) 2020-05-29 2023-01-31 Fujifilm Cellular Dynamics Inc Agregados de células duplas de epitélio pigmentado da retina e fotorreceptor, e métodos de uso dos mesmos
WO2022053130A1 (en) 2020-09-09 2022-03-17 Sid Alex Group, S.R.O. Antago-mir-155 for treatment of v-src, c-src-tyrosine kinase-induced cancers
JP2023548556A (ja) 2020-11-05 2023-11-17 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム Ｅｇｆｒ抗原を標的とする操作されたｔ細胞受容体および使用方法
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
US20240123004A1 (en) 2021-02-09 2024-04-18 University Of Houston System Oncolytic virus for systemic delivery and enhanced anti-tumor activities
WO2022175815A1 (en) 2021-02-19 2022-08-25 Pfizer Inc. Methods of protecting rna
KR20230167397A (ko) 2021-04-08 2023-12-08 얀센 바이오테크 인코포레이티드 향상된 줄기 세포 유사 기억 t 세포 조작을 위한 물질 및 방법
US20240368541A1 (en) 2021-05-03 2024-11-07 Astellas Institute For Regenerative Medicine Methods of generating mature corneal endothelial cells
WO2022235869A1 (en) 2021-05-07 2022-11-10 Astellas Institute For Regenerative Medicine Methods of generating mature hepatocytes
KR20240011831A (ko) 2021-05-26 2024-01-26 후지필름 셀룰러 다이내믹스, 인코포레이티드 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법
WO2023280807A1 (en) 2021-07-05 2023-01-12 Evaxion Biotech A/S Vaccines targeting neisseria gonorrhoeae
WO2023081813A1 (en) 2021-11-05 2023-05-11 St. Jude Children's Research Hospital, Inc. Zip cytokine receptors
US20250257388A2 (en) 2021-11-08 2025-08-14 St. Jude Children's Research Hospital, Inc. Pre-effector car-t cell gene signatures
WO2023089556A1 (en) 2021-11-22 2023-05-25 Pfizer Inc. Reducing risk of antigen mimicry in immunogenic medicaments
GB2614309A (en) 2021-12-24 2023-07-05 Stratosvir Ltd Improved vaccinia virus vectors
EP4469079A1 (en) 2022-01-28 2024-12-04 Pfizer Inc. Coronavirus antigen variants
EP4493213A1 (en) 2022-03-16 2025-01-22 University of Houston System Persistent hsv gene delivery system
GB202206507D0 (en) 2022-05-04 2022-06-15 Antion Biosciences Sa Expression construct
JP2025516318A (ja) 2022-05-04 2025-05-27 エヴァクシオン・バイオテック・アクティエセルスカブ ブドウ球菌タンパク質変異体およびトランケート
KR20250035053A (ko) 2022-06-07 2025-03-11 리제너론 파아마슈티컬스, 인크. T 세포 활성을 조절하기 위한 다중특이적 분자 및 이의 용도
EP4536687A1 (en) 2022-06-08 2025-04-16 St. Jude Children's Research Hospital, Inc. Disruption of kdm4a in t cells to enhance immunotherapy
WO2023239940A1 (en) 2022-06-10 2023-12-14 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof
CN119452078A (zh) 2022-06-29 2025-02-14 富士胶片控股美国公司 Ipsc来源的星形胶质细胞及其使用方法
WO2024059787A1 (en) 2022-09-16 2024-03-21 St. Jude Children's Research Hospital, Inc. Disruption of asxl1 in t cells to enhance immunotherapy
WO2024130212A1 (en) 2022-12-16 2024-06-20 Turnstone Biologics Corp. Recombinant vaccinia virus encoding one or more natural killer cell and t lymphocyte inhibitors
WO2024186630A1 (en) 2023-03-03 2024-09-12 Henry Ford Health System Use of extracellular vesicles for the treatment of cancer
GB202306619D0 (en) 2023-05-04 2023-06-21 Antion Biosciences Sa Cell
WO2025050009A2 (en) 2023-09-01 2025-03-06 Children's Hospital Medical Center Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
GB202402745D0 (en) 2024-02-27 2024-04-10 Antion Biosciences Sa Cell

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801545A (en) * 1983-05-19 1989-01-31 Plant Genetics, Inc. Enhanced somatic embryogenesis using maltose
US5036006A (en) * 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
GB8611818D0 (en) * 1986-05-15 1986-06-25 Shell Int Research Plant generation method
EP0331083A3 (de) * 1988-03-02 1990-11-28 Schweizerische Eidgenossenschaft Eidgenössische Technische Hochschule (Eth) Verfahren zur Herstellung transgener Pflanzen
ES2050369T3 (es) * 1989-05-12 1994-05-16 Pioneer Hi Bred Int Pistola de particulas mejorada.
WO1991002071A2 (en) * 1989-08-09 1991-02-21 Dekalb Plant Genetics Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
EP0442174A1 (en) * 1990-02-13 1991-08-21 Pioneer Hi-Bred International, Inc. Stable transformation of plant cells
DE69133512T2 (de) * 1990-11-23 2006-09-28 Bayer Bioscience N.V. Verfahren zur Transformation monokotyler Pflanzen
AU2515592A (en) * 1991-08-23 1993-03-16 University Of Florida A novel method for the production of transgenic plants
US5610042A (en) * 1991-10-07 1997-03-11 Ciba-Geigy Corporation Methods for stable transformation of wheat
AU2781892A (en) * 1991-10-07 1993-05-03 Ciba-Geigy Ag Particle gun for introducing dna into intact cells
IL101119A0 (en) * 1992-03-03 1992-11-15 Univ Ramot Transgenic wheat

Also Published As

Publication number Publication date
DE69325389T3 (de) 2007-02-08
DK0674715T3 (da) 1999-11-29
US5955362A (en) 1999-09-21
ES2134925T5 (es) 2007-06-01
US5610042A (en) 1997-03-11
EP0674715B2 (en) 2006-10-11
GR3031054T3 (en) 1999-12-31
DE69325389T2 (de) 1999-11-25
CA2151127A1 (en) 1994-06-23
EP0674715B1 (en) 1999-06-16
WO1994013822A2 (en) 1994-06-23
DE69325389D1 (de) 1999-07-22
AU5749394A (en) 1994-07-04
WO1994013822A3 (en) 1994-09-15
ATE181364T1 (de) 1999-07-15
EP0674715A1 (en) 1995-10-04
AU688297B2 (en) 1998-03-12
CA2151127C (en) 2008-03-25
DK0674715T4 (da) 2007-02-19

Similar Documents

Publication Publication Date Title
ES2134925T3 (es) Procedimiento para la transformacion estable de trigo.
PT87394A (pt) Process for plant tissue transformation
ES2124373T3 (es) Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico.
FI930377A0 (fi) Reducering kvaeveoxider under anvaendning av ureahydrolysat
YU47023B (sh) Postupak za proizvodnju izomerizovanog ekstrakta hmelja
AR002358A1 (es) Composición de enzima de celulasa de bajo remanchado, metodo para su producción y método de uso de la misma
BR9406988A (pt) Acido nucleico isolado e recombinante célula de planta,planta,fruta e processo para produzir uma planta
ES2159296T3 (es) Procedimiento para preparar 2,2-difluorocetena silil acetales y esteres de acido alfa,alfa-difluoro-beta-sililoxi-1,3-dioxolano-4-propanoico.
FR2565677B1 (fr) Lithium enrobe, procede d'enrobage de lithium metallique et source d'energie utilisant du lithium enrobe.
AU5169790A (en) New concentrated aqueous emulsions, process for preparing them and their use in the field of pesticides
ES2134184T3 (es) Empleo de etisterona para el tratamiento topico del acne o de la alopecia androgenetica.
ES2107852T3 (es) Procedimiento para la obtencion de 1,4-butanodiol.
AR000393A1 (es) Procedimiento para la preparación de un producto que contiene isobutano/isohexano
KR100256319B1 (en) Stem cell proliferation factor
TW332205B (en) A process for making a clinically efficacious HIV protease inhibitor eliminates one step in its synthesis, by an alternative convergent synthesis using 2(S)-4-picolyl-2-piperazine-t-butyl-carboxamide as an intermediate.
MX9701764A (es) Derivados de imidoacidos.
JPS6474987A (en) Novel proline acylase and its production
JPS53124693A (en) Preparation of soy malt
JPS6463374A (en) Human monoclonal antibody, antibody-forming cell, antibody-forming hybridoma and production of antibody
JPS53122692A (en) Process for sulfurizing hydrogenated catalyst
ATE207885T1 (de) Verfahren zur herstellung von ethylenisch ungesättigten isocyanaten
IT1270660B (it) Procedimento microbiologico per la preparazione di 3-oxo-4-azasteroidi-17beta-carbossi sostituiti e uso dei prodotti come inibitori dell'enzima 5alfa-riduttasi
NO981594L (no) Behandling av infeksjoner forÕrsaket av Helicobacter pylori
GB1501491A (en) Treatment of soil with biopolymers exhibiting flocculating activity produced by algae
MD244C2 (ro) Procedeu de obţinere a esterului alcoolului (S)- -cian-3-fenoxibenzilic şi a acidului 1R, cis-2,2-dimetil-3-(2,2'-dibromvinil)-ciclopropan-1-carbonic

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 674715

Country of ref document: ES