ES2137920T3 - Procedimiento para la identificacion de antigenos asociados a tumores. - Google Patents

Procedimiento para la identificacion de antigenos asociados a tumores.

Info

Publication number
ES2137920T3
ES2137920T3 ES91102608T ES91102608T ES2137920T3 ES 2137920 T3 ES2137920 T3 ES 2137920T3 ES 91102608 T ES91102608 T ES 91102608T ES 91102608 T ES91102608 T ES 91102608T ES 2137920 T3 ES2137920 T3 ES 2137920T3
Authority
ES
Spain
Prior art keywords
kda
sclc
cell lines
tumors
identification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91102608T
Other languages
English (en)
Inventor
Klaus Dr Bosslet
Bernhard Dr Auerbach
Helmut Dr Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of ES2137920T3 publication Critical patent/ES2137920T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL DESCUBRIMIENTO SE REFIERE A ANTICUERPOS MONOCLONALES (MAK) Y SUS FRAGMENTOS, QUE LIGAN EL ORIGEN DE DEFINIDOS ANTIGENOS ASOCIADOS A TUMORES PARTICULARMENTE DE PEQUEÑAS CELULAS DEL CARCINOMA DE PULMON (SCLC=SMALL CELL LUNG CARCINOMA) DE MELANOMA, DE NEUROBLASTOMA Y OTROS TUMORES NEUROECTODERMALES. EL PROCESO DESCRIBE TAMBIEN LAS CELULAS HIBRIDAS, SU FORMACION Y COMO CON LA AYUDA DE ESTE ANTICUERPO O FRAGMENTO DE ANTICUERPO, DEFINIR Y/O AISLAR EL ANTIGENO. LOS ANTICUERPOS, FRAGMENTOS DE ANTICUERPO Y ANTIGENOS PUEDEN SER USADO COMO DIAGNOSTICO, SUSTANCIA ACTIVA O PORTADORES DE SUSTANCIA ACTIVA.
ES91102608T 1990-02-22 1991-02-22 Procedimiento para la identificacion de antigenos asociados a tumores. Expired - Lifetime ES2137920T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4005630A DE4005630A1 (de) 1990-02-22 1990-02-22 Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung sowie ihre verwendung

Publications (1)

Publication Number Publication Date
ES2137920T3 true ES2137920T3 (es) 2000-01-01

Family

ID=6400763

Family Applications (2)

Application Number Title Priority Date Filing Date
ES99103484T Expired - Lifetime ES2255202T3 (es) 1990-02-22 1991-02-22 Anticuerpos monoclonales contra antigenos asociados a tumores, procedimiento para su preparacion, asi como su uso.
ES91102608T Expired - Lifetime ES2137920T3 (es) 1990-02-22 1991-02-22 Procedimiento para la identificacion de antigenos asociados a tumores.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES99103484T Expired - Lifetime ES2255202T3 (es) 1990-02-22 1991-02-22 Anticuerpos monoclonales contra antigenos asociados a tumores, procedimiento para su preparacion, asi como su uso.

Country Status (8)

Country Link
US (2) US5639622A (es)
EP (2) EP0955361B1 (es)
JP (2) JP3074193B2 (es)
AT (2) ATE185196T1 (es)
AU (2) AU661653B2 (es)
CA (1) CA2036814C (es)
DE (3) DE4005630A1 (es)
ES (2) ES2255202T3 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4005630A1 (de) * 1990-02-22 1991-09-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung sowie ihre verwendung
DE4133791A1 (de) * 1991-10-11 1993-04-15 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung und ihre verwendung
DE4212706A1 (de) * 1992-04-16 1993-10-21 Behringwerke Ag Diagnostisches Verfahren zur immunologischen Bestimmung eines oder mehrerer Analyten
EP0662147B1 (en) * 1992-09-17 1996-12-18 MERCK PATENT GmbH Small cell lung carcinoma specific antibody and antigen
US6030797A (en) * 1992-10-08 2000-02-29 Dade Behring Marburg Gmbh Monoclonal antibodies against tumor-associated antigens, processes for the preparation thereof and the use thereof
US5790761A (en) * 1992-12-11 1998-08-04 Heseltine; Gary L. Method and apparatus for the diagnosis of colorectal cancer
GB9415492D0 (en) * 1994-08-01 1994-09-21 Celltech Ltd Biological products
US5985822A (en) * 1994-12-09 1999-11-16 The Scripps Research Institute Inhibition of glial cell proliferation with N-CAM homophilic peptides
US6172474B1 (en) 1997-05-21 2001-01-09 Matsushita Electric Industrial Co., Ltd. Motor with electronic distributing configuration
US20030082188A1 (en) * 2001-10-11 2003-05-01 Tso J. Yun Treatment of prostate cancer by inhibitors of NCAM2
US7560095B2 (en) * 2003-04-22 2009-07-14 A & G Pharmaceutical, Inc. Cancer specific monoclonal antibodies
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4503143A (en) * 1982-08-20 1985-03-05 Btc Diagnostics Limited Partnership Enzyme immunoassay with two-part solution of tetramethylbenzidine as chromogen
US5284931A (en) * 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
EP0323802A3 (en) * 1987-12-24 1989-07-26 Sandoz Ag Monoclonal antibodies against, and cell surface antigen of, lung carcinoma
IL95999A0 (en) * 1989-10-20 1991-07-18 Hybritech Inc Tumor-associated antigen
DE4005630A1 (de) * 1990-02-22 1991-09-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung sowie ihre verwendung

Also Published As

Publication number Publication date
USRE37596E1 (en) 2002-03-19
CA2036814C (en) 2002-06-25
JPH0530990A (ja) 1993-02-09
EP0955361B1 (de) 2006-01-18
EP0443599A2 (de) 1991-08-28
JP3174778B2 (ja) 2001-06-11
AU7125491A (en) 1991-08-29
ATE185196T1 (de) 1999-10-15
CA2036814A1 (en) 1991-08-23
DE59109270D1 (de) 2006-04-06
DE4005630A1 (de) 1991-09-05
JP2000249710A (ja) 2000-09-14
US5639622A (en) 1997-06-17
ES2255202T3 (es) 2006-06-16
DE59109156D1 (de) 1999-11-04
EP0443599A3 (en) 1991-11-21
EP0443599B1 (de) 1999-09-29
JP3074193B2 (ja) 2000-08-07
ATE316135T1 (de) 2006-02-15
AU661653B2 (en) 1995-08-03
EP0955361A1 (de) 1999-11-10
AU677120B2 (en) 1997-04-10
AU2029295A (en) 1995-11-30

Similar Documents

Publication Publication Date Title
DE59109156D1 (de) Nachweisverfahren von tumorassoziierten Antigenen
NO874796L (no) Hybridomcellelinjer som produserer monoklonale antistoffer som reagerer med mucinepitoper.
ATE333895T1 (de) Humanisierte antikörper gegen das leukozytenadhäsionsmolekül vla-4
WO1999004265A3 (en) Cancer associated nucleic acids and polypeptides
DK0586002T3 (da) Monoklonale antistoffer, som genkender epidermisvækstfaktor-receptoren, celler og fremgangsmåder heraf og præparater indeho
WO2005062972A3 (en) Treatment of cancer with novel anti-il 13 monoclonal antibodies
DK0673255T3 (da) Monoklonale antistoffer, som specifikt binder til vaskulært tumorendotel, og anvendelser deraf
DE69924826D1 (de) Verwendung vom krebs-assoziierten antigen 5t4 zur immuntherapie
MX25027A (es) Procedimiento para preparar un vector bacteriano, vector obtenido, huesped transformado por medio del vector, moleculas de adn y metodo para preparar un polipeptido
ZA971403B (en) Tumor rejection antigens presented by HLA-B44 molecules, and uses thereof.
UY26266A1 (es) Antigeno asociado con tumores (r11) ley 17164
ATE145727T1 (de) Hybridoma ct43, das ein antikörper gegen ein mucinepitop von darmkrebs erzeugt
ATE139541T1 (de) Kollagen-bindendes protein sowie dessen herstellung
DE59209776D1 (de) Monoklonale Antikörper gegen tumorassoziierte Antigene, Verfahren zu ihrer Herstellung und ihre Verwendung
ATE208403T1 (de) Antiidiotypische antikörper die eine immunantwort gegen den rezeptor für epidermalen wachstumsfaktor induzieren
DE69942637D1 (de) Zusammensetzungen und verfahren für die therapie und diagnose von ovariumkrebs
WO1997013858A3 (en) Baboon mage-3 homologs, dna encoding the homologs, and a process for their use
ATE248914T1 (de) Allogenes vakzin und synthesemethode für selbiges
CY2524B1 (en) P75 tnf receptor promoters
NO930990D0 (no) Monoklonale anti-gangliosid antistoffer, fremstilling og anvendelse derav som tumorterapeutikum
AU653332B2 (en) Synthetic peptides which contain sequences from factor VIIa, and the use thereof
Horiot et al. New radiotherapy fractionation schemes in head and neck cancers. The EORTC trials: a benchmark
Pabst New dues rates set for 1996.
Kaiser Bastille Day bombshell over science campus.
Predy Characterization of novel antigens, detected using monoclonal antibodies raised against tissue from the central nervous system of multiple sclerosis patients

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 443599

Country of ref document: ES