ES2138536B1 - Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. - Google Patents

Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir.

Info

Publication number: ES2138536B1
Authority: ES; Spain
Prior art keywords: penciclovir; famciclovir; procedure; preparation; side chain
Prior art date: 1996-07-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

ES9701614A

Other languages

English (en)

Spanish (es)

Other versions

ES2138536A1 (es

Inventor

Victor Witold Jacewicz

David Alan Jones

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Ltd

Original Assignee

SmithKline Beecham Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-20

Filing date

1997-07-18

Publication date

2000-11-16

1997-07-18 Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd

2000-01-01 Publication of ES2138536A1 publication Critical patent/ES2138536A1/es

2000-11-16 Application granted granted Critical

2000-11-16 Publication of ES2138536B1 publication Critical patent/ES2138536B1/es

2017-07-18 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 4
JNTOCHDNEULJHD-UHFFFAOYSA-N Penciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(CCC(CO)CO)C=N2 JNTOCHDNEULJHD-UHFFFAOYSA-N 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 title abstract 3
229960004396 famciclovir Drugs 0.000 title abstract 3
GGXKWVWZWMLJEH-UHFFFAOYSA-N famcyclovir Chemical compound N1=C(N)N=C2N(CCC(COC(=O)C)COC(C)=O)C=NC2=C1 GGXKWVWZWMLJEH-UHFFFAOYSA-N 0.000 title abstract 3
229960001179 penciclovir Drugs 0.000 title abstract 3
230000000840 anti-viral effect Effects 0.000 title abstract 2
KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 6
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
-1 4-hydroxy-3-hydroxymethylbut-l-yl Chemical group 0.000 abstract 2
UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
MWBWWFOAEOYUST-UHFFFAOYSA-N 2-aminopurine Chemical compound NC1=NC=C2N=CNC2=N1 MWBWWFOAEOYUST-UHFFFAOYSA-N 0.000 abstract 1
239000003638 chemical reducing agent Substances 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
125000000714 pyrimidinyl group Chemical group 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

ES9701614A 1996-07-20 1997-07-18 Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir. Expired - Fee Related ES2138536B1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9615275.6A GB9615275D0 (en)	1996-07-20	1996-07-20	Pharmaceuticals

Publications (2)

Publication Number	Publication Date
ES2138536A1 ES2138536A1 (es)	2000-01-01
ES2138536B1 true ES2138536B1 (es)	2000-11-16

Family

ID=10797240

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES9701614A Expired - Fee Related ES2138536B1 (es)	1996-07-20	1997-07-18	Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir.

Country Status (5)

Country	Link
AT (1)	AT412645B (de)
ES (1)	ES2138536B1 (de)
GB (1)	GB9615275D0 (de)
GR (1)	GR1002943B (de)
PT (1)	PT102028B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0141927B1 (de) *	1983-08-18	1991-10-30	Beecham Group Plc	Antivirale Guanin-Derivate
SE8406538D0 (sv) *	1984-12-21	1984-12-21	Astra Laekemedel Ab	Novel derivatives of purine
GB8817270D0 (en) *	1988-07-20	1988-08-24	Beecham Group Plc	Novel process
GB8817607D0 (en) *	1988-07-23	1988-09-01	Beecham Group Plc	Novel process
GB8822236D0 (en) *	1988-09-21	1988-10-26	Beecham Group Plc	Chemical process
GB8922076D0 (en) *	1989-09-28	1989-11-15	Beecham Group Plc	Novel process
JP3906488B2 (ja) *	1995-02-21	2007-04-18	味の素株式会社	プリン誘導体の製造方法

1996
- 1996-07-20 GB GBGB9615275.6A patent/GB9615275D0/en active Pending
1997
- 1997-07-18 GR GR970100282A patent/GR1002943B/el not_active IP Right Cessation
- 1997-07-18 PT PT10202897A patent/PT102028B/pt not_active IP Right Cessation
- 1997-07-18 ES ES9701614A patent/ES2138536B1/es not_active Expired - Fee Related
- 1997-07-18 AT AT122597A patent/AT412645B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB9615275D0 (en)	1996-09-04
GR1002943B (el)	1998-07-21
MX9705480A (es)	1998-08-30
PT102028B (pt)	1999-04-30
AT412645B (de)	2005-05-25
ES2138536A1 (es)	2000-01-01
ATA122597A (de)	2004-10-15
PT102028A (pt)	1998-01-30

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