ES2140706T3 - Medicamentos. - Google Patents

Medicamentos.

Info

Publication number
ES2140706T3
ES2140706T3 ES95932166T ES95932166T ES2140706T3 ES 2140706 T3 ES2140706 T3 ES 2140706T3 ES 95932166 T ES95932166 T ES 95932166T ES 95932166 T ES95932166 T ES 95932166T ES 2140706 T3 ES2140706 T3 ES 2140706T3
Authority
ES
Spain
Prior art keywords
sup
hydrogen
medicines
integro
fluorocarbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95932166T
Other languages
English (en)
Inventor
Li Li-Bovet
Keith Arthur Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc
Application granted granted Critical
Publication of ES2140706T3 publication Critical patent/ES2140706T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

FORMULACION FARMACEUTICA EN AEROSOL QUE INCLUYE MEDICAMENTO PARTICULADO, UN FLUOROCARBONO DE UN PROPELENTE DE CLOROFLUOROCARBONO QUE CONTIENE HIDROGENO Y UN SURFACTANTE DE LA FORMULA GENERAL (I), DONDE N ES UN INTEGRO DE 1 A 18; M ES UN INTEGRO DE 0 A 17; Y R{SUP,1}, R{SUP,2}, Y R{SUP,3} SON CADA UNO DE FORMA INDEPENDIENTE UN ATOMO DE HIDROGENO O UN GRUPO C{SUB,1-4} ALQUIL.
ES95932166T 1994-09-28 1995-09-27 Medicamentos. Expired - Lifetime ES2140706T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9419536A GB9419536D0 (en) 1994-09-28 1994-09-28 Medicaments

Publications (1)

Publication Number Publication Date
ES2140706T3 true ES2140706T3 (es) 2000-03-01

Family

ID=10762008

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95932166T Expired - Lifetime ES2140706T3 (es) 1994-09-28 1995-09-27 Medicamentos.

Country Status (32)

Country Link
US (1) US5849265A (es)
EP (1) EP0783302B1 (es)
JP (1) JPH10506887A (es)
KR (1) KR100375469B1 (es)
CN (1) CN1084614C (es)
AP (1) AP742A (es)
AT (1) ATE187063T1 (es)
AU (1) AU707922B2 (es)
BG (1) BG62839B1 (es)
BR (1) BR9509108A (es)
CZ (1) CZ286356B6 (es)
DE (1) DE69513671T2 (es)
DK (1) DK0783302T3 (es)
EE (1) EE03380B1 (es)
ES (1) ES2140706T3 (es)
FI (1) FI971279L (es)
GB (1) GB9419536D0 (es)
GE (1) GEP20002140B (es)
GR (1) GR3032245T3 (es)
HU (1) HU221856B1 (es)
IS (1) IS1991B (es)
MD (1) MD1900C2 (es)
MX (1) MX9702149A (es)
NO (1) NO313658B1 (es)
NZ (1) NZ292995A (es)
OA (1) OA10603A (es)
PL (1) PL181453B1 (es)
RO (1) RO118564B1 (es)
RU (1) RU2157188C2 (es)
SK (1) SK281519B6 (es)
UA (1) UA47412C2 (es)
WO (1) WO1996009816A1 (es)

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GB9410222D0 (en) * 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
US6984404B1 (en) 1998-11-18 2006-01-10 University Of Florida Research Foundation, Inc. Methods for preparing coated drug particles and pharmaceutical formulations thereof
ES2193069T3 (es) * 1999-04-14 2003-11-01 Glaxo Group Ltd Formulacion farmaceutica en aerosol.
US6406745B1 (en) 1999-06-07 2002-06-18 Nanosphere, Inc. Methods for coating particles and particles produced thereby
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
US6451287B1 (en) 2000-05-26 2002-09-17 Smithkline Beecham Corporation Fluorinated copolymer surfactants and use thereof in aerosol compositions
GB0016876D0 (en) * 2000-07-11 2000-08-30 Astrazeneca Ab Novel formulation
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
EP2067784A3 (en) * 2000-08-05 2012-08-22 Glaxo Group Limited 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US7217409B2 (en) 2000-09-22 2007-05-15 Smithkline Beecham Corporation Alkanoic acid derivatives
GB0106046D0 (en) 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
WO2002088167A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
ATE399174T1 (de) * 2001-06-12 2008-07-15 Glaxo Group Ltd Neue anti inflammatorische 17.alpha.- heterozyklische ester von 17.beta.-carbothioat androstan derivativen
GB0118364D0 (en) * 2001-07-27 2001-09-19 Glaxo Group Ltd Compounds
JP2005501082A (ja) * 2001-08-03 2005-01-13 グラクソ　グループ　リミテッド 界面活性剤化合物およびその使用
GB0125127D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Compounds
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
EP1474376A1 (en) 2002-02-13 2004-11-10 Glaxo Group Limited Carboxylic acid compounds for use as surfactants
GB0205327D0 (en) * 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
JP4607112B2 (ja) 2003-08-11 2011-01-05 グラクソ グループ リミテッド 医薬定量噴霧式吸入器及び前記吸引器に関連する方法
EP1658105B1 (en) 2003-08-29 2018-03-14 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
US7030255B2 (en) * 2004-03-09 2006-04-18 Lyondell Chemical Technology, L.P. Oxidation process with in-situ H202 generation and polymer-encapsulated catalysts therefor
EP1811981B1 (en) * 2004-10-12 2008-08-13 Merck Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
EP1949891A1 (en) 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
DK2425820T3 (en) 2007-02-11 2015-07-13 Map Pharmaceuticals Inc A method for the therapeutic administration of DHE in order to enable quick relief of migraine, while minimizing the adverse event profile
GB0712454D0 (en) * 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5529524A (en) * 1978-08-21 1980-03-01 Toyo Aerosol Kogyo Kk Powdery aerosol composition
US4352789A (en) * 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US4965066A (en) * 1989-06-06 1990-10-23 E. I. Du Pont De Nemours And Company Intranasal administration of 3,3-disubstituted indolines
AU639008B2 (en) * 1989-06-22 1993-07-15 Alliance Pharmaceutical Corporation Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties
GB8921222D0 (en) * 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
IE67185B1 (en) * 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
DE4003272A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
CA2077354A1 (en) * 1990-03-23 1991-09-24 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
JPH05509085A (ja) * 1990-06-27 1993-12-16 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー 投与量が計測されたエーロゾル配合物の製造のための可溶性フルオロ界面活性剤の使用
US5126123A (en) * 1990-06-28 1992-06-30 Glaxo, Inc. Aerosol drug formulations

Also Published As

Publication number Publication date
PL319342A1 (en) 1997-08-04
US5849265A (en) 1998-12-15
ATE187063T1 (de) 1999-12-15
BR9509108A (pt) 1998-07-14
EE9700061A (et) 1997-08-15
MD1900C2 (ro) 2002-12-31
GR3032245T3 (en) 2000-04-27
NO971422D0 (no) 1997-03-25
NO313658B1 (no) 2002-11-11
FI971279A7 (fi) 1997-03-26
MD970134A (en) 1999-02-28
MX9702149A (es) 1998-04-30
FI971279A0 (fi) 1997-03-26
HUT77377A (hu) 1998-04-28
EP0783302A1 (en) 1997-07-16
SK281519B6 (sk) 2001-04-09
DE69513671T2 (de) 2000-04-06
CZ93697A3 (en) 1997-08-13
RO118564B1 (ro) 2003-07-30
AU3532195A (en) 1996-04-19
DK0783302T3 (da) 2000-05-29
NO971422L (no) 1997-05-23
JPH10506887A (ja) 1998-07-07
UA47412C2 (uk) 2002-07-15
NZ292995A (en) 1998-10-28
MD1900B2 (en) 2002-04-30
PL181453B1 (pl) 2001-07-31
EE03380B1 (et) 2001-04-16
CN1168630A (zh) 1997-12-24
EP0783302B1 (en) 1999-12-01
IS4438A (is) 1997-03-10
AU707922B2 (en) 1999-07-22
AP9700951A0 (en) 1997-04-30
KR970705981A (ko) 1997-11-03
WO1996009816A1 (en) 1996-04-04
DE69513671D1 (de) 2000-01-05
FI971279L (fi) 1997-03-26
CN1084614C (zh) 2002-05-15
SK39397A3 (en) 1997-10-08
AP742A (en) 1999-04-26
CZ286356B6 (cs) 2000-03-15
HU221856B1 (hu) 2003-02-28
GB9419536D0 (en) 1994-11-16
OA10603A (en) 2002-08-30
IS1991B (is) 2005-02-15
BG62839B1 (bg) 2000-09-29
KR100375469B1 (ko) 2003-10-17
BG101347A (en) 1997-12-30
RU2157188C2 (ru) 2000-10-10
GEP20002140B (en) 2000-06-25

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