ES2143453T3 - Uso de derivados de dihidropiridina para la profilaxis o el tratamiento de trastornos de la circulacion cerebral. - Google Patents

Uso de derivados de dihidropiridina para la profilaxis o el tratamiento de trastornos de la circulacion cerebral.

Info

Publication number
ES2143453T3
ES2143453T3 ES89108729T ES89108729T ES2143453T3 ES 2143453 T3 ES2143453 T3 ES 2143453T3 ES 89108729 T ES89108729 T ES 89108729T ES 89108729 T ES89108729 T ES 89108729T ES 2143453 T3 ES2143453 T3 ES 2143453T3
Authority
ES
Spain
Prior art keywords
prophylaxis
treatment
alkyl
dihydropyridine derivatives
circulation disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108729T
Other languages
English (en)
Inventor
Takeshi Uchida
Yutaka Ohtaki
Masahiro Watanabe
Atsuyuki Ashimori
Chikara Fukaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Yoshitomi Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical Industries Ltd filed Critical Yoshitomi Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of ES2143453T3 publication Critical patent/ES2143453T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

UNA COMPOSICION CEREBRAL HIPERQUINERICA QUE CONTIENE COMO INGREDIENTE EFECTIVO AL MENOS UN DERIVADO DE DIHIDROPIRIDINA DE LA FORMULA(I), DONDE R1, R2 Y R3 IGUALES O NO SON INDEPENDIENTMENTE UN ALQUILO, CICLOALQUILO O UN ALCOXIALQUILO, R4 Y R5 IGUALES O NO , SON INDEPENDIENTEMENTE UN H UN HALOGENO, NITRO UN ALQUILO HALOGENADO, UN ALQUILSULFONILO, UN ALCOXI HALOGENADO, UN ALQUILSULFINILO, CIANO; X ES VINILENO Y AR ES UN FENILO, QUE PUEDE SER SUSTITUIDO O UNA SAL DE ADICION ACIDA EN CANTIDAD EFECTIVA.
ES89108729T 1988-05-19 1989-05-12 Uso de derivados de dihidropiridina para la profilaxis o el tratamiento de trastornos de la circulacion cerebral. Expired - Lifetime ES2143453T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12261288 1988-05-19

Publications (1)

Publication Number Publication Date
ES2143453T3 true ES2143453T3 (es) 2000-05-16

Family

ID=14840258

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108729T Expired - Lifetime ES2143453T3 (es) 1988-05-19 1989-05-12 Uso de derivados de dihidropiridina para la profilaxis o el tratamiento de trastornos de la circulacion cerebral.

Country Status (6)

Country Link
EP (1) EP0342577B1 (es)
JP (1) JP2577994B2 (es)
KR (1) KR0137141B1 (es)
CA (1) CA1328076C (es)
DE (1) DE68929177T2 (es)
ES (1) ES2143453T3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2838282B2 (ja) * 1988-12-29 1998-12-16 吉富製薬株式会社 血管攣縮治療剤
EP0463407B1 (en) * 1990-06-25 2002-02-13 Mitsubishi Pharma Corporation Use of dihydropyridins in cardiotonic pharmaceutical compositions
US5691339A (en) * 1993-08-25 1997-11-25 The Green Cross Corporation Circulatory disorder improving agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
JPH0686429B2 (ja) * 1986-08-27 1994-11-02 株式会社ミドリ十字 ジヒドロピリジン誘導体
JP2838282B2 (ja) * 1988-12-29 1998-12-16 吉富製薬株式会社 血管攣縮治療剤

Also Published As

Publication number Publication date
JPH0262824A (ja) 1990-03-02
JP2577994B2 (ja) 1997-02-05
DE68929177D1 (de) 2000-04-20
EP0342577B1 (en) 2000-03-15
EP0342577A3 (en) 1991-12-04
CA1328076C (en) 1994-03-29
KR890016970A (ko) 1989-12-14
EP0342577A2 (en) 1989-11-23
DE68929177T2 (de) 2000-10-19
KR0137141B1 (ko) 1998-04-25

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