ES2144844T3 - Derivados ureido biologicamente activos utiles en el tratamiento de la esclerosis en placas. - Google Patents
Derivados ureido biologicamente activos utiles en el tratamiento de la esclerosis en placas.Info
- Publication number
- ES2144844T3 ES2144844T3 ES97904356T ES97904356T ES2144844T3 ES 2144844 T3 ES2144844 T3 ES 2144844T3 ES 97904356 T ES97904356 T ES 97904356T ES 97904356 T ES97904356 T ES 97904356T ES 2144844 T3 ES2144844 T3 ES 2144844T3
- Authority
- ES
- Spain
- Prior art keywords
- ureid
- treatment
- sclerosis
- derivatives
- plates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000034189 Sclerosis Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
EL USO EN LA PREPARACION DE UN MEDICAMENTO PARA SU USO EN EL TRATAMIENTO DE LA ESCLEROSIS MULTIPLE DE UN COMPUESTO QUE ES UN DERIVADO DE UREIDO DE FORMULA (I) EN EL QUE CADA UNO DE M Y N, QUE SON IGUALES, ES UN ENTERO DE 1 A 3; Y CADA UNO DE LOS GRUPOS R, QUE SON IGUALES, ES UN GRUPO NAFTILO SUSTITUIDO CON DE 1 A 3 GRUPOS DE ACIDO SULFONICO, O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9602721.4A GB9602721D0 (en) | 1996-02-09 | 1996-02-09 | Biologically active ureido derivatives useful in the treatment of multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2144844T3 true ES2144844T3 (es) | 2000-06-16 |
Family
ID=10788461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97904356T Expired - Lifetime ES2144844T3 (es) | 1996-02-09 | 1997-01-24 | Derivados ureido biologicamente activos utiles en el tratamiento de la esclerosis en placas. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5859046A (es) |
| EP (1) | EP0820284B1 (es) |
| JP (1) | JPH11504041A (es) |
| KR (1) | KR19980703718A (es) |
| AR (1) | AR005724A1 (es) |
| AT (1) | ATE189388T1 (es) |
| AU (1) | AU1720097A (es) |
| BR (1) | BR9702075A (es) |
| CA (1) | CA2217008A1 (es) |
| DE (1) | DE69701243T2 (es) |
| DK (1) | DK0820284T3 (es) |
| EA (1) | EA000166B1 (es) |
| ES (1) | ES2144844T3 (es) |
| GB (1) | GB9602721D0 (es) |
| GR (1) | GR3033332T3 (es) |
| HU (1) | HUP9900796A2 (es) |
| IL (1) | IL121808A0 (es) |
| NO (1) | NO974651L (es) |
| PL (1) | PL322717A1 (es) |
| PT (1) | PT820284E (es) |
| WO (1) | WO1997028796A1 (es) |
| ZA (1) | ZA97902B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999027939A1 (en) * | 1997-12-04 | 1999-06-10 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Ureido derivatives of poly-4-amino-2-carboxy-1-methyl pyrrole compounds for inhibition of inflammation |
| GB9727524D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Synergistic antitumor composition containing a biologically active ureido compound |
| US6348464B1 (en) | 1999-11-12 | 2002-02-19 | Guilford Pharmaceuticals, Inc. | Pyrrolecarbonylimino derivatives as naaladase inhibitors |
| EP1599461B1 (en) | 2003-03-03 | 2009-06-10 | Eisai Corporation of North America | THIOLACTONES AS NAALADase INHIBITORS |
| EP3381897A1 (en) | 2017-03-27 | 2018-10-03 | Leadiant Biosciences SA | Derivatives of the disodium 2,2'-{carbonylbis[imino-3,1-phenylenecarbonylimino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino]}dinaphthalene-1,5-disulfonate salt and related compounds as heparanase inhibitors for the treatment of cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9304589D0 (en) * | 1993-03-05 | 1993-04-21 | Erba Carlo Spa | Biologically active ureido derivatives useful as antimetastic agents |
| GB9307948D0 (en) * | 1993-04-16 | 1993-06-02 | Erba Carlo Spa | Biologically active ureido derivatives useful in the treatment of lentivirus-induced disease |
-
1996
- 1996-02-09 GB GBGB9602721.4A patent/GB9602721D0/en active Pending
-
1997
- 1997-01-24 EA EA199700302A patent/EA000166B1/ru not_active IP Right Cessation
- 1997-01-24 WO PCT/EP1997/000412 patent/WO1997028796A1/en not_active Ceased
- 1997-01-24 KR KR1019970707118A patent/KR19980703718A/ko not_active Withdrawn
- 1997-01-24 CA CA002217008A patent/CA2217008A1/en not_active Abandoned
- 1997-01-24 DE DE69701243T patent/DE69701243T2/de not_active Expired - Fee Related
- 1997-01-24 PT PT97904356T patent/PT820284E/pt unknown
- 1997-01-24 AU AU17200/97A patent/AU1720097A/en not_active Abandoned
- 1997-01-24 IL IL12180897A patent/IL121808A0/xx unknown
- 1997-01-24 HU HU9900796A patent/HUP9900796A2/hu unknown
- 1997-01-24 DK DK97904356T patent/DK0820284T3/da active
- 1997-01-24 JP JP9528110A patent/JPH11504041A/ja active Pending
- 1997-01-24 BR BR9702075A patent/BR9702075A/pt not_active Application Discontinuation
- 1997-01-24 ES ES97904356T patent/ES2144844T3/es not_active Expired - Lifetime
- 1997-01-24 PL PL97322717A patent/PL322717A1/xx unknown
- 1997-01-24 US US08/930,598 patent/US5859046A/en not_active Expired - Fee Related
- 1997-01-24 EP EP97904356A patent/EP0820284B1/en not_active Expired - Lifetime
- 1997-01-24 AT AT97904356T patent/ATE189388T1/de not_active IP Right Cessation
- 1997-02-04 ZA ZA9700902A patent/ZA97902B/xx unknown
- 1997-02-06 AR ARP970100464A patent/AR005724A1/es unknown
- 1997-10-08 NO NO974651A patent/NO974651L/no unknown
-
2000
- 2000-04-26 GR GR20000401016T patent/GR3033332T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA97902B (en) | 1997-08-01 |
| DE69701243D1 (de) | 2000-03-09 |
| GB9602721D0 (en) | 1996-04-10 |
| HUP9900796A2 (hu) | 1999-07-28 |
| GR3033332T3 (en) | 2000-09-29 |
| BR9702075A (pt) | 1998-06-09 |
| WO1997028796A1 (en) | 1997-08-14 |
| DK0820284T3 (da) | 2000-07-24 |
| EP0820284A1 (en) | 1998-01-28 |
| AU1720097A (en) | 1997-08-28 |
| ATE189388T1 (de) | 2000-02-15 |
| EP0820284B1 (en) | 2000-02-02 |
| MX9707673A (es) | 1997-11-29 |
| PL322717A1 (en) | 1998-02-16 |
| PT820284E (pt) | 2000-07-31 |
| JPH11504041A (ja) | 1999-04-06 |
| US5859046A (en) | 1999-01-12 |
| EA199700302A1 (ru) | 1998-04-30 |
| AR005724A1 (es) | 1999-07-14 |
| DE69701243T2 (de) | 2000-09-07 |
| EA000166B1 (ru) | 1998-10-29 |
| KR19980703718A (ko) | 1998-12-05 |
| NO974651D0 (no) | 1997-10-08 |
| IL121808A0 (en) | 1998-02-22 |
| CA2217008A1 (en) | 1997-08-14 |
| NO974651L (no) | 1997-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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