ES2146232T3 - Ensayo no invasivo. - Google Patents
Ensayo no invasivo.Info
- Publication number
- ES2146232T3 ES2146232T3 ES93917056T ES93917056T ES2146232T3 ES 2146232 T3 ES2146232 T3 ES 2146232T3 ES 93917056 T ES93917056 T ES 93917056T ES 93917056 T ES93917056 T ES 93917056T ES 2146232 T3 ES2146232 T3 ES 2146232T3
- Authority
- ES
- Spain
- Prior art keywords
- perception
- methods
- infrared detection
- color
- invasive test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000001514 detection method Methods 0.000 abstract 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000013528 artificial neural network Methods 0.000 abstract 1
- 230000004456 color vision Effects 0.000 abstract 1
- 238000004737 colorimetric analysis Methods 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 238000012850 discrimination method Methods 0.000 abstract 1
- 230000004438 eyesight Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000008447 perception Effects 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N2021/3129—Determining multicomponents by multiwavelength light
- G01N2021/3137—Determining multicomponents by multiwavelength light with selection of wavelengths after the sample
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
HA SIDO DESARROLLADO UN NUEVO METODO DE DETECCION DE NO INVASION PARA LA GLUCOSA Y OTROS CONSTITUYENTES DE INTERES EN UNA MUESTRA. EL APARATO Y LOS METODOS DE LA INVENCION PROVEEN UN ANALOGO DE PERCEPCION DE COLOR DE LA VISION HUMANA, PREFERIBLEMENTE EN LA REGION INFRARROJA PROXIMA, REEMPLAZANDO LOS ESPECTROFOTOMETROS USADOS EN OTROS METODOS DE DETECCION DE INFRARROJOS PROXIMOS DE NO INVASION. UNA PLURALIDAD DE UNIDADES DETECTORAS SON USADOS, CADA UNA CUBRIENDO UNA REGION ANCHA DEL ESPECTRO DETECTADO, PERCEPCION DE COLOR PARALELA Y COLORIMETRIA. EN ALGUNAS CIRCUNSTANCIAS, UNA RED NEURAL ES USADA PARA EL ANALISIS, PERMITIENDO AL SISTEMA A APRENDER. ES TAMBIEN DESCRITO UN NUEVO METODO DE DISCRIMINACION DE FONDO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/914,265 US5321265A (en) | 1992-07-15 | 1992-07-15 | Non-invasive testing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2146232T3 true ES2146232T3 (es) | 2000-08-01 |
Family
ID=25434103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93917056T Expired - Lifetime ES2146232T3 (es) | 1992-07-15 | 1993-07-08 | Ensayo no invasivo. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5321265A (es) |
| EP (2) | EP0650591B1 (es) |
| JP (1) | JPH08502350A (es) |
| AU (1) | AU4670293A (es) |
| CA (1) | CA2140239C (es) |
| DE (1) | DE69328363T2 (es) |
| ES (1) | ES2146232T3 (es) |
| WO (1) | WO1994002837A1 (es) |
Families Citing this family (101)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434412A (en) * | 1992-07-15 | 1995-07-18 | Myron J. Block | Non-spectrophotometric measurement of analyte concentrations and optical properties of objects |
| US6420709B1 (en) | 1992-07-15 | 2002-07-16 | Optix Lp | Methods of minimizing scattering and improving tissue sampling in non-invasive testing and imaging |
| US6222189B1 (en) | 1992-07-15 | 2001-04-24 | Optix, Lp | Methods of enhancing optical signals by mechanical manipulation in non-invasive testing |
| US5818048A (en) * | 1992-07-15 | 1998-10-06 | Optix Lp | Rapid non-invasive optical analysis using broad bandpass spectral processing |
| US5672875A (en) * | 1992-07-15 | 1997-09-30 | Optix Lp | Methods of minimizing scattering and improving tissue sampling in non-invasive testing and imaging |
| US5424545A (en) * | 1992-07-15 | 1995-06-13 | Myron J. Block | Non-invasive non-spectrophotometric infrared measurement of blood analyte concentrations |
| US6411832B1 (en) | 1992-07-15 | 2002-06-25 | Optix Lp | Method of improving reproducibility of non-invasive measurements |
| DE4339067A1 (de) * | 1993-11-16 | 1995-05-18 | Jenoptik Jena Gmbh | Verfahren und Anordnung zur nichtinvasiven, transkutanen Bestimmung von Stoffkonzentrationen in Körperflüssigkeit oder Gewebe des Menschen |
| US5459317A (en) * | 1994-02-14 | 1995-10-17 | Ohio University | Method and apparatus for non-invasive detection of physiological chemicals, particularly glucose |
| US5477326A (en) * | 1994-06-30 | 1995-12-19 | Bayer Corporation | Spectrophotometer arrangement with multi-detector readhead |
| US5553613A (en) * | 1994-08-17 | 1996-09-10 | Pfizer Inc. | Non invasive blood analyte sensor |
| US5803909A (en) * | 1994-10-06 | 1998-09-08 | Hitachi, Ltd. | Optical system for measuring metabolism in a body and imaging method |
| SG38866A1 (en) * | 1995-07-31 | 1997-04-17 | Instrumentation Metrics Inc | Liquid correlation spectrometry |
| US6152876A (en) * | 1997-04-18 | 2000-11-28 | Rio Grande Medical Technologies, Inc. | Method for non-invasive blood analyte measurement with improved optical interface |
| US6212424B1 (en) | 1998-10-29 | 2001-04-03 | Rio Grande Medical Technologies, Inc. | Apparatus and method for determination of the adequacy of dialysis by non-invasive near-infrared spectroscopy |
| US6240306B1 (en) | 1995-08-09 | 2001-05-29 | Rio Grande Medical Technologies, Inc. | Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration |
| US5655530A (en) * | 1995-08-09 | 1997-08-12 | Rio Grande Medical Technologies, Inc. | Method for non-invasive blood analyte measurement with improved optical interface |
| US6240309B1 (en) * | 1995-10-06 | 2001-05-29 | Hitachi, Ltd. | Optical measurement instrument for living body |
| US20060184047A1 (en) * | 1995-11-17 | 2006-08-17 | Yuichi Yamashita | Optical measurement instrument for living body |
| US5748308A (en) * | 1996-02-02 | 1998-05-05 | Abbott Laboratories | Programmable standard for use in an apparatus and process for the noninvasive measurement of optically absorbing compounds |
| US5788632A (en) * | 1996-03-19 | 1998-08-04 | Abbott Laboratories | Apparatus and process for the non-invasive measurement of optically active compounds |
| US5961451A (en) * | 1997-04-07 | 1999-10-05 | Motorola, Inc. | Noninvasive apparatus having a retaining member to retain a removable biosensor |
| US7890158B2 (en) * | 2001-06-05 | 2011-02-15 | Lumidigm, Inc. | Apparatus and method of biometric determination using specialized optical spectroscopy systems |
| US6560352B2 (en) | 1999-10-08 | 2003-05-06 | Lumidigm, Inc. | Apparatus and method of biometric identification or verification of individuals using optical spectroscopy |
| US6628809B1 (en) | 1999-10-08 | 2003-09-30 | Lumidigm, Inc. | Apparatus and method for identification of individuals by near-infrared spectrum |
| US6246893B1 (en) | 1997-06-12 | 2001-06-12 | Tecmed Incorporated | Method and device for glucose concentration measurement with special attention to blood glucose determinations |
| US6043492A (en) * | 1997-10-27 | 2000-03-28 | Industrial Technology Research Institute | Non-invasive blood glucose meter |
| US6070093A (en) | 1997-12-02 | 2000-05-30 | Abbott Laboratories | Multiplex sensor and method of use |
| US6002953A (en) * | 1998-05-06 | 1999-12-14 | Optix Lp | Non-invasive IR transmission measurement of analyte in the tympanic membrane |
| US6662031B1 (en) | 1998-05-18 | 2003-12-09 | Abbott Laboratoies | Method and device for the noninvasive determination of hemoglobin and hematocrit |
| US7043287B1 (en) | 1998-05-18 | 2006-05-09 | Abbott Laboratories | Method for modulating light penetration depth in tissue and diagnostic applications using same |
| US6241663B1 (en) | 1998-05-18 | 2001-06-05 | Abbott Laboratories | Method for improving non-invasive determination of the concentration of analytes in a biological sample |
| US6526298B1 (en) | 1998-05-18 | 2003-02-25 | Abbott Laboratories | Method for the non-invasive determination of analytes in a selected volume of tissue |
| US6662030B2 (en) | 1998-05-18 | 2003-12-09 | Abbott Laboratories | Non-invasive sensor having controllable temperature feature |
| SE512098C2 (sv) | 1998-05-19 | 2000-01-24 | Agrovision Ab | Koncentrationsbestämning av en komponent i en blandning av minst två komponenter |
| US6441388B1 (en) | 1998-10-13 | 2002-08-27 | Rio Grande Medical Technologies, Inc. | Methods and apparatus for spectroscopic calibration model transfer |
| US7098037B2 (en) | 1998-10-13 | 2006-08-29 | Inlight Solutions, Inc. | Accommodating subject and instrument variations in spectroscopic determinations |
| US6157041A (en) | 1998-10-13 | 2000-12-05 | Rio Grande Medical Technologies, Inc. | Methods and apparatus for tailoring spectroscopic calibration models |
| US6370407B1 (en) | 1999-07-27 | 2002-04-09 | Tecmed, Incorporated | System for improving the sensitivity and stability of optical polarimetric measurements |
| US6919566B1 (en) * | 1999-08-31 | 2005-07-19 | Nir Diagnostics Inc. | Method of calibrating a spectroscopic device |
| US6816605B2 (en) | 1999-10-08 | 2004-11-09 | Lumidigm, Inc. | Methods and systems for biometric identification of individuals using linear optical spectroscopy |
| US6452180B1 (en) | 2000-03-28 | 2002-09-17 | Advanced Micro Devices, Inc. | Infrared inspection for determining residual films on semiconductor devices |
| US6983176B2 (en) | 2001-04-11 | 2006-01-03 | Rio Grande Medical Technologies, Inc. | Optically similar reference samples and related methods for multivariate calibration models used in optical spectroscopy |
| US6862091B2 (en) | 2001-04-11 | 2005-03-01 | Inlight Solutions, Inc. | Illumination device and method for spectroscopic analysis |
| US6865408B1 (en) | 2001-04-11 | 2005-03-08 | Inlight Solutions, Inc. | System for non-invasive measurement of glucose in humans |
| US6574490B2 (en) | 2001-04-11 | 2003-06-03 | Rio Grande Medical Technologies, Inc. | System for non-invasive measurement of glucose in humans |
| US7126682B2 (en) * | 2001-04-11 | 2006-10-24 | Rio Grande Medical Technologies, Inc. | Encoded variable filter spectrometer |
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| DE602004003414T2 (de) * | 2003-04-03 | 2007-09-27 | Matsushita Electric Industrial Co., Ltd., Kadoma | Methode und Gerät zur Konzentrationmessung einer spezifischen Komponente |
| US7394919B2 (en) | 2004-06-01 | 2008-07-01 | Lumidigm, Inc. | Multispectral biometric imaging |
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| US7627151B2 (en) * | 2003-04-04 | 2009-12-01 | Lumidigm, Inc. | Systems and methods for improved biometric feature definition |
| US7539330B2 (en) | 2004-06-01 | 2009-05-26 | Lumidigm, Inc. | Multispectral liveness determination |
| US7347365B2 (en) * | 2003-04-04 | 2008-03-25 | Lumidigm, Inc. | Combined total-internal-reflectance and tissue imaging systems and methods |
| US7545963B2 (en) | 2003-04-04 | 2009-06-09 | Lumidigm, Inc. | Texture-biometrics sensor |
| WO2004090786A2 (en) | 2003-04-04 | 2004-10-21 | Lumidigm, Inc. | Multispectral biometric sensor |
| US7751594B2 (en) | 2003-04-04 | 2010-07-06 | Lumidigm, Inc. | White-light spectral biometric sensors |
| US7668350B2 (en) | 2003-04-04 | 2010-02-23 | Lumidigm, Inc. | Comparative texture analysis of tissue for biometric spoof detection |
| US7092101B2 (en) * | 2003-04-16 | 2006-08-15 | Duke University | Methods and systems for static multimode multiplex spectroscopy |
| US6975892B2 (en) * | 2003-10-21 | 2005-12-13 | Oculir, Inc. | Methods for non-invasive analyte measurement from the conjunctiva |
| US6958039B2 (en) * | 2003-05-02 | 2005-10-25 | Oculir, Inc. | Method and instruments for non-invasive analyte measurement |
| US6968222B2 (en) | 2003-05-02 | 2005-11-22 | Oculir, Inc. | Methods and device for non-invasive analyte measurement |
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| US7263213B2 (en) | 2003-12-11 | 2007-08-28 | Lumidigm, Inc. | Methods and systems for estimation of personal characteristics from biometric measurements |
| US20080009688A1 (en) * | 2004-04-14 | 2008-01-10 | Oculir, Inc. | Methods for non-invasive analyte measurement |
| US20060258919A1 (en) * | 2004-04-14 | 2006-11-16 | Oculir, Inc. | Non-Invasive Analyte Measurement Device for Measuring Tears and Other Ocular Elements Using Electromagnetic Radiation and Method of Using the Same |
| US8229185B2 (en) | 2004-06-01 | 2012-07-24 | Lumidigm, Inc. | Hygienic biometric sensors |
| US7508965B2 (en) | 2004-06-01 | 2009-03-24 | Lumidigm, Inc. | System and method for robust fingerprint acquisition |
| US20110163163A1 (en) * | 2004-06-01 | 2011-07-07 | Lumidigm, Inc. | Multispectral barcode imaging |
| US8787630B2 (en) | 2004-08-11 | 2014-07-22 | Lumidigm, Inc. | Multispectral barcode imaging |
| WO2006100685A2 (en) * | 2005-03-25 | 2006-09-28 | Cnoga Holdings Ltd | Optical sensor device and image processing unit for measuring chemical concentrations, chemical saturations and biophysical parameters |
| US7801338B2 (en) | 2005-04-27 | 2010-09-21 | Lumidigm, Inc. | Multispectral biometric sensors |
| DE102006002500B4 (de) * | 2006-01-13 | 2008-02-28 | Hottinger Baldwin Messtechnik Gmbh | Optisches Spektrometer |
| US8355545B2 (en) | 2007-04-10 | 2013-01-15 | Lumidigm, Inc. | Biometric detection using spatial, temporal, and/or spectral techniques |
| US7995808B2 (en) | 2006-07-19 | 2011-08-09 | Lumidigm, Inc. | Contactless multispectral biometric capture |
| KR101349892B1 (ko) | 2006-07-19 | 2014-01-13 | 루미다임 인크. | 다중 생체인식 다중 스펙트럼 이미저 |
| US8175346B2 (en) | 2006-07-19 | 2012-05-08 | Lumidigm, Inc. | Whole-hand multispectral biometric imaging |
| US7801339B2 (en) | 2006-07-31 | 2010-09-21 | Lumidigm, Inc. | Biometrics with spatiospectral spoof detection |
| US7804984B2 (en) | 2006-07-31 | 2010-09-28 | Lumidigm, Inc. | Spatial-spectral fingerprint spoof detection |
| WO2008077007A1 (en) * | 2006-12-19 | 2008-06-26 | Cytyc Corporation | Method for analyzing blood content of cytological specimens |
| KR101484566B1 (ko) | 2007-03-21 | 2015-01-20 | 루미다임 인크. | 국소적으로 일관된 피처를 기초로 하는 생체인식 |
| US20090155919A1 (en) * | 2007-12-17 | 2009-06-18 | Optix, Llp | High throughput drug screening method |
| US8274565B2 (en) * | 2008-12-31 | 2012-09-25 | Iscon Video Imaging, Inc. | Systems and methods for concealed object detection |
| JP5572210B2 (ja) | 2009-05-22 | 2014-08-13 | スリーエム イノベイティブ プロパティズ カンパニー | 多層比色センサアレイ |
| US8872908B2 (en) | 2009-08-26 | 2014-10-28 | Lumidigm, Inc | Dual-imager biometric sensor |
| US8570149B2 (en) | 2010-03-16 | 2013-10-29 | Lumidigm, Inc. | Biometric imaging using an optical adaptive interface |
| US8694067B2 (en) * | 2011-02-15 | 2014-04-08 | General Electric Company | Sensor, apparatus and method for non-invasively monitoring blood characteristics of a subject |
| WO2016054079A1 (en) | 2014-09-29 | 2016-04-07 | Zyomed Corp. | Systems and methods for blood glucose and other analyte detection and measurement using collision computing |
| US9554738B1 (en) | 2016-03-30 | 2017-01-31 | Zyomed Corp. | Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing |
| US20180098733A1 (en) * | 2016-08-31 | 2018-04-12 | Medika Healthcare Co., Ltd. | Non-invasive glucose monitoring system |
| CN110680341B (zh) * | 2019-10-25 | 2021-05-18 | 北京理工大学 | 一种基于可见光图像的非侵入式血糖检测装置 |
| TWI758891B (zh) * | 2020-09-30 | 2022-03-21 | 國立成功大學 | 濃度感測系統與方法 |
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|---|---|---|---|---|
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-
1992
- 1992-07-15 US US07/914,265 patent/US5321265A/en not_active Expired - Lifetime
-
1993
- 1993-07-08 EP EP93917056A patent/EP0650591B1/en not_active Expired - Lifetime
- 1993-07-08 EP EP99202777A patent/EP0967478A1/en not_active Withdrawn
- 1993-07-08 DE DE69328363T patent/DE69328363T2/de not_active Expired - Fee Related
- 1993-07-08 ES ES93917056T patent/ES2146232T3/es not_active Expired - Lifetime
- 1993-07-08 AU AU46702/93A patent/AU4670293A/en not_active Abandoned
- 1993-07-08 CA CA002140239A patent/CA2140239C/en not_active Expired - Fee Related
- 1993-07-08 JP JP6504507A patent/JPH08502350A/ja active Pending
- 1993-07-08 WO PCT/US1993/006461 patent/WO1994002837A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0967478A1 (en) | 1999-12-29 |
| WO1994002837A1 (en) | 1994-02-03 |
| CA2140239C (en) | 2005-06-28 |
| EP0650591B1 (en) | 2000-04-12 |
| DE69328363D1 (de) | 2000-05-18 |
| DE69328363T2 (de) | 2000-08-10 |
| JPH08502350A (ja) | 1996-03-12 |
| US5321265A (en) | 1994-06-14 |
| EP0650591A4 (en) | 1995-11-08 |
| EP0650591A1 (en) | 1995-05-03 |
| CA2140239A1 (en) | 1994-02-03 |
| AU4670293A (en) | 1994-02-14 |
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