ES2147621T3 - Deteccion no-invasiva de la integracion de un transgenico en mamiferos. - Google Patents

Deteccion no-invasiva de la integracion de un transgenico en mamiferos.

Info

Publication number
ES2147621T3
ES2147621T3 ES95941424T ES95941424T ES2147621T3 ES 2147621 T3 ES2147621 T3 ES 2147621T3 ES 95941424 T ES95941424 T ES 95941424T ES 95941424 T ES95941424 T ES 95941424T ES 2147621 T3 ES2147621 T3 ES 2147621T3
Authority
ES
Spain
Prior art keywords
methods
transgenic
mammals
integration
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95941424T
Other languages
English (en)
Inventor
Christopher H Contag
Pamela R Contag
David A Benaron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27170688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2147621(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Application granted granted Critical
Publication of ES2147621T3 publication Critical patent/ES2147621T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Eye Examination Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Push-Button Switches (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

SE REVELAN METODOS Y COMPOSICIONES PARA DETECTAR Y LOCALIZAR LUZ ORIGINADA A PARTIR DE UN MAMIFERO. TAMBIEN SE REVELAN METODOS PARA DIRIGIR LA EMISION DE LUZ A REGIONES SELECCIONADAS, ASI COMO PARA EL SEGUIMIENTO DE ENTIDADES DENTRO DEL MAMIFERO. ADEMAS, SE REVELAN MODELOS ANIMALES PARA ESTADOS MORBOSOS, ASI COMO METODOS PARA LOCALIZAR Y SEGUIR LA PROGRESION DE LA ENFERMEDAD O DE UN PATOGENO DENTRO DEL ANIMAL, Y PARA DETECTAR SELECTIVAMENTE COMPUESTOS SUPUESTAMENTE TERAPEUTICOS EFICACES EN LA INHIBICION DE LA ENFERMEDAD O EL PATOGENO.
ES95941424T 1994-07-01 1995-11-17 Deteccion no-invasiva de la integracion de un transgenico en mamiferos. Expired - Lifetime ES2147621T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/270,631 US5650135A (en) 1994-07-01 1994-07-01 Non-invasive localization of a light-emitting conjugate in a mammal
PCT/US1995/015040 WO1997018841A1 (en) 1994-07-01 1995-11-17 Non-invasive localization of a light-emitting conjugate in a mammal
CA002237983A CA2237983C (en) 1994-07-01 1995-11-17 Non-invasive localization of a light-emitting conjugate in a mammal

Publications (1)

Publication Number Publication Date
ES2147621T3 true ES2147621T3 (es) 2000-09-16

Family

ID=27170688

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95941424T Expired - Lifetime ES2147621T3 (es) 1994-07-01 1995-11-17 Deteccion no-invasiva de la integracion de un transgenico en mamiferos.
ES99124640T Pending ES2152198T1 (es) 1994-07-01 1995-11-17 Localizacion no invasora de un conjugado emisor de luz en mamiferos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES99124640T Pending ES2152198T1 (es) 1994-07-01 1995-11-17 Localizacion no invasora de un conjugado emisor de luz en mamiferos.

Country Status (12)

Country Link
US (1) US5650135A (es)
EP (2) EP0861093B1 (es)
JP (1) JP3786704B2 (es)
AT (1) ATE193453T1 (es)
AU (1) AU4285096A (es)
BR (1) BR9510664A (es)
CA (1) CA2237983C (es)
DE (2) DE1016419T1 (es)
DK (1) DK0861093T3 (es)
ES (2) ES2147621T3 (es)
GR (1) GR3034110T3 (es)
WO (1) WO1997018841A1 (es)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
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US5650135A (en) 1997-07-22

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