ES2148694T3 - Asociacion de fenofibrato y vitamina e y su uso en terapeutica. - Google Patents

Asociacion de fenofibrato y vitamina e y su uso en terapeutica.

Info

Publication number
ES2148694T3
ES2148694T3 ES96400133T ES96400133T ES2148694T3 ES 2148694 T3 ES2148694 T3 ES 2148694T3 ES 96400133 T ES96400133 T ES 96400133T ES 96400133 T ES96400133 T ES 96400133T ES 2148694 T3 ES2148694 T3 ES 2148694T3
Authority
ES
Spain
Prior art keywords
micronisate
vitamin
phenofibrate
therapeutics
association
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96400133T
Other languages
English (en)
Inventor
Alan Dunlap Edgar
Francois Bellamy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Fournier SAS
Original Assignee
Laboratories Fournier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Fournier SAS filed Critical Laboratories Fournier SAS
Application granted granted Critical
Publication of ES2148694T3 publication Critical patent/ES2148694T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA NUEVA ASOCIACION DE FENOFIBRATO Y DE UNA SUSTANCIA VITAMINICA E, QUE SE CARACTERIZA POR QUE COMPRENDE: A) UN COMICRONIZADO DE Y FENOFIBRATO CON UN AGENTE TENSIOACTIVO SOLIDO, Y B) UNA SUSTANCIA VITAMINICA E ELEGIDA ENTRE EL CONJUNTO CONSTITUIDO POR LOS TOCOFEROLES, SUS ESTERES CON ACIDOS ORGANICOS Y SUS MEZCLAS, CON LAS DOS SIGUIENTES CONDICIONES: 1) DICHO CO-MICRONIZADO CONTIENE 33 A 200 MG DE FENOFIBRATO Y LA CANTIDAD DE DICHA SUSTANCIA VITAMINICA E REPRESENTA 100 A 600 IU, Y 2) LA RELACION RA) DE LA CANTIDAD DE FENOFIBRATO EXPRESADA EN MG A LA CANTIDAD DE DICHA SUSTANCIA VITAMINICA E EXPRESADA EN IU ESTA COMPRENDIDO ENTRE 0,33 Y 2 MG/IU. SE REFIERE TAMBIEN A LA UTILIZACION DE ESTA ASOCIACION EN USO TERAPEUTICO.
ES96400133T 1995-02-02 1996-01-19 Asociacion de fenofibrato y vitamina e y su uso en terapeutica. Expired - Lifetime ES2148694T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9501216A FR2730231B1 (fr) 1995-02-02 1995-02-02 Association de fenofibrate et de vitamine e, utilisation en therapeutique

Publications (1)

Publication Number Publication Date
ES2148694T3 true ES2148694T3 (es) 2000-10-16

Family

ID=9475777

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96400133T Expired - Lifetime ES2148694T3 (es) 1995-02-02 1996-01-19 Asociacion de fenofibrato y vitamina e y su uso en terapeutica.

Country Status (10)

Country Link
US (1) US5880148A (es)
EP (1) EP0724877B1 (es)
JP (1) JP4746726B2 (es)
AT (1) ATE194078T1 (es)
DE (1) DE69608974T2 (es)
DK (1) DK0724877T3 (es)
ES (1) ES2148694T3 (es)
FR (1) FR2730231B1 (es)
GR (1) GR3034147T3 (es)
PT (1) PT724877E (es)

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GB0114532D0 (en) * 2001-06-14 2001-08-08 Jagotec Ag Novel compositions
GB0119480D0 (en) * 2001-08-09 2001-10-03 Jagotec Ag Novel compositions
US20080145402A1 (en) * 2001-09-10 2008-06-19 Abbott Cardiovascular Systems Inc. Medical Devices Containing Rapamycin Analogs
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US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
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CA2481371A1 (en) * 2002-03-11 2003-09-18 Peter Zahradka Use of ppar alpha agonists for the treatment of vascular and renal diseases
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Also Published As

Publication number Publication date
JP4746726B2 (ja) 2011-08-10
PT724877E (pt) 2000-12-29
GR3034147T3 (en) 2000-11-30
DE69608974D1 (de) 2000-08-03
JPH08253416A (ja) 1996-10-01
US5880148A (en) 1999-03-09
EP0724877A1 (fr) 1996-08-07
FR2730231A1 (fr) 1996-08-09
DE69608974T2 (de) 2001-02-08
ATE194078T1 (de) 2000-07-15
DK0724877T3 (da) 2000-10-16
EP0724877B1 (fr) 2000-06-28
FR2730231B1 (fr) 1997-04-04

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