ES2149978T3 - Nuevo tiodepsipeptido aislado a partir de un actinomiceto marino. - Google Patents

Nuevo tiodepsipeptido aislado a partir de un actinomiceto marino.

Info

Publication number
ES2149978T3
ES2149978T3 ES95914502T ES95914502T ES2149978T3 ES 2149978 T3 ES2149978 T3 ES 2149978T3 ES 95914502 T ES95914502 T ES 95914502T ES 95914502 T ES95914502 T ES 95914502T ES 2149978 T3 ES2149978 T3 ES 2149978T3
Authority
ES
Spain
Prior art keywords
isolated
new
marine
tiodepsipeptide
actinomicet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95914502T
Other languages
English (en)
Inventor
Julia Perez Baz
Francisco Romero Millan
Quesada Theresa Garcia De
Dolores Garcia Gravalos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmamar SA
Original Assignee
Pharmamar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmamar SA filed Critical Pharmamar SA
Application granted granted Critical
Publication of ES2149978T3 publication Critical patent/ES2149978T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION ESTA DIRIGIDA A UN NUEVO DEPSIPEPTIDO QUE HA SIDO AISLADO DE UNA NUEVA CADENA MARINA L-13-ACM2-092 QUE PERTENECE A LA FAMILIA MICROMONOSPORACEAE. AQUI SE DESCRIBE SU PRODUCCION MEDIANTE FERMENTACION AEROBICA BAJO CONDICIONES CONTROLADAS DE LA CADENA, Y EL AISLAMIENTO Y PURIFICACION DE PM93135. EL COMPUESTO Y EL CALDO DE FERMENTACION DEMUESTRAN ACTIVIDAD SIGNIFICATIVA FRENTE A DIFERENTES LINEAS DE CELULAS DE CANCER. EL COMPUESTO TAMBIEN MUESTRA ACTIVIDAD CONTRA DIFERENTES BACTERIAS GRAM POSITIVAS.
ES95914502T 1994-04-06 1995-04-06 Nuevo tiodepsipeptido aislado a partir de un actinomiceto marino. Expired - Lifetime ES2149978T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/224,628 US5681813A (en) 1994-04-06 1994-04-06 Thiodepsipeptide isolated from a marine actinomycete

Publications (1)

Publication Number Publication Date
ES2149978T3 true ES2149978T3 (es) 2000-11-16

Family

ID=22841484

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95914502T Expired - Lifetime ES2149978T3 (es) 1994-04-06 1995-04-06 Nuevo tiodepsipeptido aislado a partir de un actinomiceto marino.

Country Status (10)

Country Link
US (3) US5681813A (es)
EP (1) EP0702691B1 (es)
JP (1) JP3830964B2 (es)
AT (1) ATE194359T1 (es)
DE (1) DE69517761T2 (es)
DK (1) DK0702691T3 (es)
ES (1) ES2149978T3 (es)
GR (1) GR3034347T3 (es)
PT (1) PT702691E (es)
WO (1) WO1995027730A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE331730T1 (de) * 1999-01-13 2006-07-15 Astellas Pharma Inc Neue depsipeptid-verbindung
MXPA03005625A (es) * 2000-12-21 2004-12-03 Scripps Research Inst Analogos de tiocoralina y be-22179.
ES2406107T3 (es) * 2007-12-14 2013-06-05 Pharma Mar S.A. Compuestos antitumorales
US11332480B2 (en) 2017-04-27 2022-05-17 Pharma Mar, S.A. Antitumoral compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366309A (en) * 1980-03-14 1982-12-28 Schering Corporation Derivatives of antibiotic AR-5 components

Also Published As

Publication number Publication date
US6214793B1 (en) 2001-04-10
DE69517761T2 (de) 2001-03-01
WO1995027730A1 (en) 1995-10-19
US5849540A (en) 1998-12-15
JPH08512330A (ja) 1996-12-24
EP0702691A1 (en) 1996-03-27
JP3830964B2 (ja) 2006-10-11
PT702691E (pt) 2000-11-30
ATE194359T1 (de) 2000-07-15
US5681813A (en) 1997-10-28
DK0702691T3 (da) 2000-10-16
GR3034347T3 (en) 2000-12-29
EP0702691B1 (en) 2000-07-05
DE69517761D1 (de) 2000-08-10

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