ES2151480T3 - Procedimiento para preparar productos intermedios de nizatidina y compuestos relacionados. - Google Patents
Procedimiento para preparar productos intermedios de nizatidina y compuestos relacionados.Info
- Publication number
- ES2151480T3 ES2151480T3 ES92304475T ES92304475T ES2151480T3 ES 2151480 T3 ES2151480 T3 ES 2151480T3 ES 92304475 T ES92304475 T ES 92304475T ES 92304475 T ES92304475 T ES 92304475T ES 2151480 T3 ES2151480 T3 ES 2151480T3
- Authority
- ES
- Spain
- Prior art keywords
- nizatidine
- prepare
- procedure
- related compounds
- intermediate products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- SGXXNSQHWDMGGP-IZZDOVSWSA-N nizatidine Chemical compound [O-][N+](=O)\C=C(/NC)NCCSCC1=CSC(CN(C)C)=N1 SGXXNSQHWDMGGP-IZZDOVSWSA-N 0.000 title abstract 2
- 229960004872 nizatidine Drugs 0.000 title abstract 2
- 239000013067 intermediate product Substances 0.000 title 1
- YFTNQZCRJPNJTG-UHFFFAOYSA-N [2-(aminomethyl)-1,3-thiazol-4-yl]methanol Chemical compound NCC1=NC(CO)=CS1 YFTNQZCRJPNJTG-UHFFFAOYSA-N 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Saccharide Compounds (AREA)
Abstract
LA PRESENTE INVENCION PROPORCIONA UN NUEVO PROCESO PARA LA PREPARACION DE UN 2-(AMINOMETIL)-4-TIAZOLEMETANOL Y NUEVOS PRODUCTOS INTERMEDIOS UTILES EN ESTE PROCESO. LOS COMPUESTOS PRODUCIDOS POR EL PROCESO DE LA PRESENTE INVENCION SON UTILES PARA LA SINTETIZACION DE COMPUESTOS ANTI-ULCERA COMO NIZATIDINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70352691A | 1991-05-21 | 1991-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2151480T3 true ES2151480T3 (es) | 2001-01-01 |
Family
ID=24825733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92304475T Expired - Lifetime ES2151480T3 (es) | 1991-05-21 | 1992-05-18 | Procedimiento para preparar productos intermedios de nizatidina y compuestos relacionados. |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP0960880A1 (es) |
| JP (2) | JP3504280B2 (es) |
| KR (1) | KR100214184B1 (es) |
| AT (1) | ATE197296T1 (es) |
| BR (1) | BR9201895A (es) |
| CA (3) | CA2343023C (es) |
| DE (1) | DE69231541T2 (es) |
| DK (1) | DK0515121T3 (es) |
| ES (1) | ES2151480T3 (es) |
| GR (1) | GR3035263T3 (es) |
| HU (1) | HU219459B (es) |
| IE (1) | IE921623A1 (es) |
| IL (1) | IL101915A (es) |
| MX (1) | MX9202347A (es) |
| PT (1) | PT515121E (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK160611C (da) * | 1979-09-04 | 1991-09-16 | Bristol Myers Squibb Co | Analogifremgangsmaade til fremstilling af 3,4-disubstituerede 1,2,5-thiadiazol-1-oxider og -1,1-dioxider |
| US4375547A (en) * | 1980-10-02 | 1983-03-01 | Eli Lilly And Company | N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine |
| US4468517A (en) * | 1983-05-12 | 1984-08-28 | Eli Lilly And Company | Synthesis of thiazoles |
-
1992
- 1992-05-18 EP EP99202448A patent/EP0960880A1/en not_active Withdrawn
- 1992-05-18 EP EP92304475A patent/EP0515121B1/en not_active Expired - Lifetime
- 1992-05-18 IL IL10191592A patent/IL101915A/en active IP Right Grant
- 1992-05-18 PT PT92304475T patent/PT515121E/pt unknown
- 1992-05-18 AT AT92304475T patent/ATE197296T1/de not_active IP Right Cessation
- 1992-05-18 ES ES92304475T patent/ES2151480T3/es not_active Expired - Lifetime
- 1992-05-18 DK DK92304475T patent/DK0515121T3/da active
- 1992-05-18 DE DE69231541T patent/DE69231541T2/de not_active Expired - Fee Related
- 1992-05-19 MX MX9202347A patent/MX9202347A/es not_active IP Right Cessation
- 1992-05-19 KR KR1019920008444A patent/KR100214184B1/ko not_active Expired - Fee Related
- 1992-05-19 HU HU9201664A patent/HU219459B/hu not_active IP Right Cessation
- 1992-05-20 CA CA002343023A patent/CA2343023C/en not_active Expired - Lifetime
- 1992-05-20 CA CA002343336A patent/CA2343336C/en not_active Expired - Lifetime
- 1992-05-20 CA CA002069055A patent/CA2069055C/en not_active Expired - Lifetime
- 1992-05-20 BR BR929201895A patent/BR9201895A/pt not_active Application Discontinuation
- 1992-05-20 JP JP12726292A patent/JP3504280B2/ja not_active Expired - Fee Related
- 1992-07-01 IE IE162392A patent/IE921623A1/en not_active Application Discontinuation
-
2001
- 2001-01-17 GR GR20010400083T patent/GR3035263T3/el not_active IP Right Cessation
-
2002
- 2002-07-22 JP JP2002212664A patent/JP2003040876A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX9202347A (es) | 1994-06-30 |
| DK0515121T3 (da) | 2000-11-27 |
| CA2069055C (en) | 2001-08-07 |
| JP2003040876A (ja) | 2003-02-13 |
| IL101915A0 (en) | 1992-12-30 |
| PT515121E (pt) | 2001-04-30 |
| KR100214184B1 (ko) | 1999-08-02 |
| CA2343336C (en) | 2004-10-19 |
| EP0960880A1 (en) | 1999-12-01 |
| JP3504280B2 (ja) | 2004-03-08 |
| EP0515121A1 (en) | 1992-11-25 |
| IL101915A (en) | 1996-12-05 |
| CA2343336A1 (en) | 1992-11-22 |
| EP0515121B1 (en) | 2000-11-02 |
| DE69231541T2 (de) | 2001-06-07 |
| HU219459B (hu) | 2001-04-28 |
| HU9201664D0 (en) | 1992-08-28 |
| ATE197296T1 (de) | 2000-11-15 |
| CA2069055A1 (en) | 1992-11-22 |
| CA2343023C (en) | 2002-02-05 |
| DE69231541D1 (de) | 2000-12-07 |
| IE921623A1 (en) | 1992-12-02 |
| GR3035263T3 (en) | 2001-04-30 |
| BR9201895A (pt) | 1993-01-05 |
| JPH05155889A (ja) | 1993-06-22 |
| HUT62870A (en) | 1993-06-28 |
| KR920021563A (ko) | 1992-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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