ES2152977T3 - Producto rehidratable y procedimiento para su preparacion. - Google Patents
Producto rehidratable y procedimiento para su preparacion.Info
- Publication number
- ES2152977T3 ES2152977T3 ES94912895T ES94912895T ES2152977T3 ES 2152977 T3 ES2152977 T3 ES 2152977T3 ES 94912895 T ES94912895 T ES 94912895T ES 94912895 T ES94912895 T ES 94912895T ES 2152977 T3 ES2152977 T3 ES 2152977T3
- Authority
- ES
- Spain
- Prior art keywords
- linked
- layer
- contact
- layers
- dry hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000017 hydrogel Substances 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 239000006096 absorbing agent Substances 0.000 abstract 1
- 230000007797 corrosion Effects 0.000 abstract 1
- 238000005260 corrosion Methods 0.000 abstract 1
- 230000036571 hydration Effects 0.000 abstract 1
- 238000006703 hydration reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Electrotherapy Devices (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Materials For Medical Uses (AREA)
- Laminated Bodies (AREA)
Abstract
SE PRESENTA UN BIOELECTRODO IONTOFORETICO HIDRATABLE QUE INCLUYE UNA PLURALIDAD DE CAPAS DE MATERIAL CAPAZ DE ABSORBER Y MANTENER UN FLUIDO IONIZADO CUANDO SE COLOCA EN CONTACTO CON EL FLUIDO. EN UNA CONFORMACION, SE UTILIZA UNA CAPA DE HIDROGEL SECO, ALTAMENTE ENLAZADO CON UNA SEGUNDA CAPA DE UN HIDROGEL SECO, MAS SUAVEMENTE ENLAZADO. CUANDO LA CAPA DE HIDROGEL SECO, SUAVEMENTE ENLAZADO SE COLOCA DE MANERA QUE ESTE EN CONTACTO CON LA PIEL DURANTE LA IONTOFORESIS, LOS IONES DEL MEDICAMENTO SE CONCENTRARAN CERCA DE LA PIEL. CUANDO LA CAPA ALTAMENTE ENLAZADA SE SITUA CERCA DEL MIEMBRO CONDUCTOR, SE REDUCEN LOS EFECTOS INDESEABLES DE LA HIDROLISIS Y LA CORROSION DEL MIEMBRO CONDUCTOR. EN OTRA CONFORMACION, LAS CAPAS ADYACENTES SE MANTIENEN AL MENOS PARCIALMENTE FUERA DE CONTACTO UNA DE LA OTRA DE MANERA QUE SE MEJORE LA PROPORCION DE HIDRATACION MEDIANTE LA DISPOSICION ENTRE LAS CAPAS DE ELEMENTOS SEPARADORES TALES COMO AZUCAR U OTRAS PARTICULAS QUE PUEDAN DISOLVERSE O CELULOSA O FORMANDO UNAESTRUCTURA TRIDIMENSIONAL SOBRE LAS MISMAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/038,798 US5328455A (en) | 1989-07-21 | 1993-03-29 | Rehydratable product and method of preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2152977T3 true ES2152977T3 (es) | 2001-02-16 |
Family
ID=21901962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94912895T Expired - Lifetime ES2152977T3 (es) | 1993-03-29 | 1994-03-29 | Producto rehidratable y procedimiento para su preparacion. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5328455A (es) |
| EP (1) | EP0693952B1 (es) |
| JP (1) | JP2800852B2 (es) |
| KR (2) | KR960701677A (es) |
| AU (1) | AU6526794A (es) |
| CA (1) | CA2158948C (es) |
| DE (1) | DE69426294T2 (es) |
| ES (1) | ES2152977T3 (es) |
| NO (1) | NO953710L (es) |
| WO (1) | WO1994022527A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050159699A1 (en) * | 1993-09-30 | 2005-07-21 | Vyteris, Inc. | Iontophoretic drug delivery device and reservoir and method of making same |
| US6377847B1 (en) * | 1993-09-30 | 2002-04-23 | Vyteris, Inc. | Iontophoretic drug delivery device and reservoir and method of making same |
| US5547677A (en) * | 1994-05-20 | 1996-08-20 | Novavax, Inc. | Antimicrobial oil-in-water emulsions |
| US5990179A (en) * | 1995-04-28 | 1999-11-23 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
| US5840056A (en) * | 1995-06-15 | 1998-11-24 | Empi, Inc. | Iontophoresis electrode |
| US5788666A (en) * | 1995-06-15 | 1998-08-04 | Empi, Inc. | Iontophoresis electrode |
| US5941843A (en) * | 1996-07-12 | 1999-08-24 | Empi, Inc. | Iontophoresis electrode |
| US5871461A (en) * | 1996-07-12 | 1999-02-16 | Empi, Inc. | Method of making an iontophoresis electrode |
| US5857993A (en) * | 1996-07-12 | 1999-01-12 | Empi, Inc. | Process of making an iontophoresis electrode |
| US6018679A (en) * | 1997-01-29 | 2000-01-25 | Novartis Finance Corp. | Iontophoretic transdermal delivery and control of adverse side-effects |
| US5846217A (en) * | 1997-07-29 | 1998-12-08 | Iomed, Inc. | Iontophoretic bioelectrode and method of using same |
| US6038464A (en) | 1998-02-09 | 2000-03-14 | Axelgaard Manufacturing Co., Ltd. | Medical electrode |
| US6112908A (en) * | 1998-02-11 | 2000-09-05 | Rentiers Machinery Pty, Ltd. | Membrane laminates and methods for their preparation |
| US6275728B1 (en) | 1998-12-22 | 2001-08-14 | Alza Corporation | Thin polymer film drug reservoirs |
| US6497887B1 (en) * | 2000-04-13 | 2002-12-24 | Color Access, Inc. | Membrane delivery system |
| US6629968B1 (en) * | 2000-06-30 | 2003-10-07 | Vyteris, Inc. | Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode |
| US6553255B1 (en) | 2000-10-27 | 2003-04-22 | Aciont Inc. | Use of background electrolytes to minimize flux variability during iontophoresis |
| US7171276B2 (en) * | 2001-06-29 | 2007-01-30 | Abbott Laboratories | Hydrogel and scrim assembly for use with electro-acupuncture device with stimulation electrodes |
| US20030065285A1 (en) * | 2001-07-23 | 2003-04-03 | Higuchi William I. | Method and apparatus for increasing flux during reverse iontophoresis |
| JP2006116086A (ja) * | 2004-10-21 | 2006-05-11 | Tokuyama Corp | イオントフォレーシス装置用作用極構造体及びイオントフォレーシス装置 |
| US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
| US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
| US20100072060A1 (en) * | 2008-09-25 | 2010-03-25 | Tyco Healthcare Group Lp | Biomedical Electrode and Method of Formation Thereof |
| US20100075532A1 (en) * | 2008-09-25 | 2010-03-25 | Tyco Healthcare Group Lp | Fluorescent Marker for Detecting Gel or Lack of Gel |
| EP2401027B1 (en) | 2009-02-26 | 2017-11-01 | The University of North Carolina At Chapel Hill | Interventional drug delivery system |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4362165A (en) * | 1980-01-08 | 1982-12-07 | Ipco Corporation | Stable gel electrode |
| US4383529A (en) * | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| US4416274A (en) * | 1981-02-23 | 1983-11-22 | Motion Control, Inc. | Ion mobility limiting iontophoretic bioelectrode |
| JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
| US4419092A (en) * | 1981-11-06 | 1983-12-06 | Motion Control, Inc. | Iontophoretic electrode structure |
| US4731926A (en) * | 1985-02-19 | 1988-03-22 | Drug Delivery Systems Inc. | Method of manufacturing disposable and/or replenishable transdermal drug applicators |
| US4921475A (en) * | 1983-08-18 | 1990-05-01 | Drug Delivery Systems Inc. | Transdermal drug patch with microtubes |
| US4747819A (en) * | 1984-10-29 | 1988-05-31 | Medtronic, Inc. | Iontophoretic drug delivery |
| US4702732A (en) * | 1984-12-24 | 1987-10-27 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands |
| US4708149A (en) * | 1985-06-14 | 1987-11-24 | Jens Axelgaard | Electrical stimulation electrode |
| US4867166A (en) * | 1985-06-14 | 1989-09-19 | Jens Axelgaard | Electrical stimulation electrode |
| US4710191A (en) * | 1985-12-16 | 1987-12-01 | Jonergin, Inc. | Therapeutic device for the administration of medicaments |
| US4915685A (en) * | 1986-03-19 | 1990-04-10 | Petelenz Tomasz J | Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange |
| US4777954A (en) * | 1986-06-30 | 1988-10-18 | Nepera Inc. | Conductive adhesive medical electrode assemblies |
| US4684558A (en) * | 1986-06-30 | 1987-08-04 | Nepera Inc. | Adhesive polyethylene oxide hydrogel sheet and its production |
| JPS63102768A (ja) * | 1986-10-20 | 1988-05-07 | 山之内製薬株式会社 | イオントフオレ−シス用の新規プラスタ−構造体 |
| US4989607A (en) * | 1989-03-30 | 1991-02-05 | Preston Keusch | Highly conductive non-stringy adhesive hydrophilic gels and medical electrode assemblies manufactured therefrom |
| US5087242A (en) * | 1989-07-21 | 1992-02-11 | Iomed, Inc. | Hydratable bioelectrode |
| US5236412A (en) * | 1989-07-21 | 1993-08-17 | Iomed, Inc. | Rehydratable product and method of preparation thereof |
| US5084006A (en) * | 1990-03-30 | 1992-01-28 | Alza Corporation | Iontopheretic delivery device |
| US5087241A (en) * | 1990-07-24 | 1992-02-11 | Empi, Inc. | Iontophoresis electrode with reservoir and injection site |
| US5158537A (en) * | 1990-10-29 | 1992-10-27 | Alza Corporation | Iontophoretic delivery device and method of hydrating same |
| JPH0611308B2 (ja) * | 1991-04-19 | 1994-02-16 | 克弥 高須 | 脂肪吸引装置およびその器具 |
-
1993
- 1993-03-29 US US08/038,798 patent/US5328455A/en not_active Expired - Fee Related
-
1994
- 1994-03-29 ES ES94912895T patent/ES2152977T3/es not_active Expired - Lifetime
- 1994-03-29 KR KR1019950704210A patent/KR960701677A/ko active Granted
- 1994-03-29 AU AU65267/94A patent/AU6526794A/en not_active Abandoned
- 1994-03-29 WO PCT/US1994/003396 patent/WO1994022527A1/en not_active Ceased
- 1994-03-29 DE DE69426294T patent/DE69426294T2/de not_active Expired - Fee Related
- 1994-03-29 JP JP6522288A patent/JP2800852B2/ja not_active Expired - Lifetime
- 1994-03-29 CA CA002158948A patent/CA2158948C/en not_active Expired - Fee Related
- 1994-03-29 KR KR1019950704210A patent/KR0151926B1/ko not_active Expired - Fee Related
- 1994-03-29 EP EP94912895A patent/EP0693952B1/en not_active Expired - Lifetime
-
1995
- 1995-09-20 NO NO953710A patent/NO953710L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2800852B2 (ja) | 1998-09-21 |
| DE69426294D1 (de) | 2000-12-21 |
| EP0693952A4 (en) | 1996-04-17 |
| EP0693952A1 (en) | 1996-01-31 |
| NO953710D0 (no) | 1995-09-20 |
| AU6526794A (en) | 1994-10-24 |
| JPH08504644A (ja) | 1996-05-21 |
| CA2158948C (en) | 2000-12-12 |
| NO953710L (no) | 1995-09-20 |
| CA2158948A1 (en) | 1994-10-13 |
| KR960701677A (ko) | 1996-03-28 |
| WO1994022527A1 (en) | 1994-10-13 |
| EP0693952B1 (en) | 2000-11-15 |
| US5328455A (en) | 1994-07-12 |
| DE69426294T2 (de) | 2001-05-23 |
| KR0151926B1 (ko) | 1998-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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