ES2152993T3 - Procedimiento de obtencion de un aerosol viral. - Google Patents

Procedimiento de obtencion de un aerosol viral.

Info

Publication number
ES2152993T3
ES2152993T3 ES94931633T ES94931633T ES2152993T3 ES 2152993 T3 ES2152993 T3 ES 2152993T3 ES 94931633 T ES94931633 T ES 94931633T ES 94931633 T ES94931633 T ES 94931633T ES 2152993 T3 ES2152993 T3 ES 2152993T3
Authority
ES
Spain
Prior art keywords
procedure
obtaining
viral
aerosol
viral aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94931633T
Other languages
English (en)
Inventor
Claude Sene
Didier Lamy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Application granted granted Critical
Publication of ES2152993T3 publication Critical patent/ES2152993T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO DE PREPARACION DE UN AEROSOL VIRAL A PARTIR DE UNA SUSPENSION VIRAL DILUIDA PREPARADA POR DILUCION DE UN VIRUS EN UNA SOLUCION ACUOSA QUE COMPRENDE DE 6 A 12 G/L DE UNA SAL DE UN CATION MONOVALENTE, O DE 50 A 100 G/L DE UNA HEXOSA, QUE SE NEBULIZA CON UNA PRESION GASEOSA DE 0,5 A 3,5 BARES, O UNA FRECUENCIA ULTRASONORA DE 2 A 5MHZ. LA INVENCION SE REFIERE TAMBIEN A LA COMPOSICION AEROSOL OBTENIDA.
ES94931633T 1993-10-26 1994-10-26 Procedimiento de obtencion de un aerosol viral. Expired - Lifetime ES2152993T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9312743A FR2711523B1 (fr) 1993-10-26 1993-10-26 Procédé de préparation d'un aérosol viral.

Publications (1)

Publication Number Publication Date
ES2152993T3 true ES2152993T3 (es) 2001-02-16

Family

ID=9452211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94931633T Expired - Lifetime ES2152993T3 (es) 1993-10-26 1994-10-26 Procedimiento de obtencion de un aerosol viral.

Country Status (13)

Country Link
US (3) US5952220A (es)
EP (1) EP0680315B1 (es)
JP (1) JP4110329B2 (es)
AT (1) ATE198704T1 (es)
AU (1) AU683954B2 (es)
CA (1) CA2152505C (es)
DE (1) DE69426596T2 (es)
DK (1) DK0680315T3 (es)
ES (1) ES2152993T3 (es)
FR (1) FR2711523B1 (es)
GR (1) GR3035541T3 (es)
PT (1) PT680315E (es)
WO (1) WO1995011664A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751343B1 (fr) * 1996-07-16 1998-12-18 Transgene Sa Procede de conservation de virus recombinants infectieux, suspension aqueuse virale et utilisation comme medicament
DE60040147D1 (de) * 1999-05-28 2008-10-16 Targeted Genetics Corp Methoden und zusammensetzungen zur reduktion des tumor-nekrosis-faktor-spiegels (tnf) bei tnf-assoziierten erkrankungen
JP2003505518A (ja) * 1999-07-29 2003-02-12 ケース ウェスタン リザーブ ユニバーシティ セルピン酵素複合体受容体を介する増強された送達
EP1250447B1 (en) * 1999-11-29 2011-12-21 Midwest Oilseeds, Inc. Methods, media and apparatus for the introduction of molecules into plant cells and bacteria using aerosol beams
US20020198139A1 (en) * 2001-05-17 2002-12-26 Deutschman Clifford S. Method of preventing acute pulmonary cell injury
EP1575976A4 (en) 2001-11-02 2006-08-23 Insert Therapeutics Inc METHODS AND COMPOSITIONS FOR THE THERAPEUTIC USE OF RNA INTERFERENCE
US6845929B2 (en) * 2002-03-22 2005-01-25 Ali Dolatabadi High efficiency nozzle for thermal spray of high quality, low oxide content coatings
DK1648931T3 (da) 2003-07-21 2011-03-07 Transgene Sa Multifunktionelle cytokiner
EP1866414B9 (en) 2005-03-31 2012-10-03 Calando Pharmaceuticals, Inc. Inhibitors of ribonucleotide reductase subunit 2 and uses thereof
EP2202239A1 (en) 2005-11-01 2010-06-30 Alnylam Pharmaceuticals Inc. RNAI inhibition of influenza virus replication
US8229398B2 (en) * 2006-01-30 2012-07-24 Qualcomm Incorporated GSM authentication in a CDMA network
US7846908B2 (en) * 2006-03-16 2010-12-07 Alnylam Pharmaceuticals, Inc. RNAi modulation of TGF-beta and therapeutic uses thereof
EP2392583A1 (en) * 2006-05-19 2011-12-07 Alnylam Europe AG. RNAi modulation of Aha and therapeutic uses thereof
DE102007020578A1 (de) * 2007-05-02 2008-11-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Wässrige Aerosolzubereitungen enthaltend therapeutisch wirksame Mikroorganismen oder Teile von Mikroorganismen und Verfahren zur Erzeugung entsprechender Aerosole
CN102037123A (zh) 2008-04-04 2011-04-27 卡兰多制药股份有限公司 Epas1抑制剂的组合物和用途
WO2012078425A1 (en) * 2010-12-07 2012-06-14 University Of Florida Research Foundation, Inc. Spraying system and methods of use thereof
JP6430949B2 (ja) 2012-10-23 2018-11-28 エモリー ユニバーシティ Ｇｍ−ｃｓｆとｉｌ−４のコンジュゲート、組成物、ならびにそれに関連する方法
US10253071B2 (en) 2013-06-03 2019-04-09 Beth Israel Deaconess Medical Center, Inc. Selectin inhibitors, composition, and uses related thereto
CN106794243A (zh) 2014-08-26 2017-05-31 哈斯福制药公司 新型免疫剂及其使用方法
US20210401968A1 (en) 2018-03-08 2021-12-30 Hsf Pharmaceuticals Sa Localized activation of virus replicatio boosts herpesvirus-vectored vaccines
CA3113648A1 (en) 2018-09-21 2020-03-26 University Of Connecticut Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome
EP3653716A1 (en) 2018-11-19 2020-05-20 HSF Pharmaceuticals Replication-competent controlled alpha-herpesvirus virus vectors and uses therefore
WO2020163703A1 (en) * 2019-02-08 2020-08-13 Krystal Biotech, Inc. Compositions and methods for delivering cftr polypeptides
WO2021214279A1 (en) 2020-04-24 2021-10-28 Hsf Pharmaceuticals Replication-competent controlled herpesviruses expressing a sars cov-2 antigen
EP4291306A1 (en) 2021-02-09 2023-12-20 University of Georgia Research Foundation, Inc. Human monoclonal antibodies against pneumococcal antigens
WO2023198757A1 (en) 2022-04-14 2023-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Alpha-1-antitrypsin for treating paramyxoviridae or orthomyxoviridae infections
WO2025214935A1 (en) 2024-04-11 2025-10-16 Hsf Pharmaceuticals Sa Recombinant alphaherpesvirus vectors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039656A (en) * 1971-12-10 1977-08-02 Bayer Aktiengesellschaft Production of attenuated viruses
FR2423217A2 (fr) * 1978-03-10 1979-11-16 Anvar Procede de vaccination contre la myxomatose
US4554158A (en) * 1983-04-07 1985-11-19 Simonsen Laboratories, Inc. Modified live sendai virus vaccine for administering through an aerosol and method of producing the same
US4649911A (en) * 1983-09-08 1987-03-17 Baylor College Of Medicine Small particle aerosol generator for treatment of respiratory disease including the lungs
JP2656944B2 (ja) * 1987-04-30 1997-09-24 クーパー ラボラトリーズ タンパク質性治療剤のエアロゾール化
US5240846A (en) 1989-08-22 1993-08-31 The Regents Of The University Of Michigan Gene therapy vector for cystic fibrosis
US6013638A (en) * 1991-10-02 2000-01-11 The United States Of America As Represented By The Department Of Health And Human Services Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung
US5858784A (en) * 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
WO1993012240A1 (en) * 1991-12-17 1993-06-24 The Regents Of The University Of California Gene therapy for cystic fibrosis transmembrane conductance regulator activity (cftr)
US7769623B2 (en) * 2002-12-17 2010-08-03 International Business Machines Corporation Method and system for conducting online marketing research in a controlled manner

Also Published As

Publication number Publication date
US20020106349A1 (en) 2002-08-08
EP0680315A1 (fr) 1995-11-08
DE69426596D1 (de) 2001-02-22
AU8063994A (en) 1995-05-22
EP0680315B1 (fr) 2001-01-17
AU683954B2 (en) 1997-11-27
DK0680315T3 (da) 2001-02-26
CA2152505C (fr) 2005-04-26
GR3035541T3 (en) 2001-06-29
FR2711523A1 (fr) 1995-05-05
ATE198704T1 (de) 2001-02-15
DE69426596T2 (de) 2001-05-31
CA2152505A1 (fr) 1995-05-04
WO1995011664A1 (fr) 1995-05-04
US5952220A (en) 1999-09-14
PT680315E (pt) 2001-05-31
JP4110329B2 (ja) 2008-07-02
JPH08505405A (ja) 1996-06-11
US6582694B2 (en) 2003-06-24
US6344194B1 (en) 2002-02-05
FR2711523B1 (fr) 1996-02-16

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