ES2153864T3 - Mejoras introducidas en particulas soportes para uso en inhaladores de polvo seco. - Google Patents

Mejoras introducidas en particulas soportes para uso en inhaladores de polvo seco.

Info

Publication number
ES2153864T3
ES2153864T3 ES94931098T ES94931098T ES2153864T3 ES 2153864 T3 ES2153864 T3 ES 2153864T3 ES 94931098 T ES94931098 T ES 94931098T ES 94931098 T ES94931098 T ES 94931098T ES 2153864 T3 ES2153864 T3 ES 2153864T3
Authority
ES
Spain
Prior art keywords
particles
dry powder
powder inhalers
improvements introduced
particles supports
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94931098T
Other languages
English (en)
Inventor
John Nicholas Staniforth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectura Ltd
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectura Ltd filed Critical Vectura Ltd
Application granted granted Critical
Publication of ES2153864T3 publication Critical patent/ES2153864T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)

Abstract

EN UN METODO PARA PRODUCIR PARTICULAS ADECUADAS COMO PARTICULAS PORTADORAS EN INHALADORES DE POLVO SECO, LAS PARTICULAS (I) DE UN TAMAÑO ADECUADO PARA SU USO EN INHALADORES DE POLVO SECO SE TRATAN DE MANERA QUE DESHALOJEN LOS GRANOS PEQUEÑOS DE LA SUPERFICIE DE LAS PARTICULAS, SIN CAMBIAR SUBSTANCIALMENTE EL TAMAÑO DE LAS PARTICULAS DURANTE EL TRATAMIENTO. EL TRATAMIENTO OTORGA UNA EFICIENCIA MEJORADA DE REDISPERSION DE LAS PARTICULAS ACTIVAS DESDE LA SUPERFICIE DE LAS PARTICULAS PORTADORAS.
ES94931098T 1993-10-26 1994-10-26 Mejoras introducidas en particulas soportes para uso en inhaladores de polvo seco. Expired - Lifetime ES2153864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939322014A GB9322014D0 (en) 1993-10-26 1993-10-26 Improvements in and relating to carrier particles for use in dry powder inhalers

Publications (1)

Publication Number Publication Date
ES2153864T3 true ES2153864T3 (es) 2001-03-16

Family

ID=10744106

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94931098T Expired - Lifetime ES2153864T3 (es) 1993-10-26 1994-10-26 Mejoras introducidas en particulas soportes para uso en inhaladores de polvo seco.

Country Status (9)

Country Link
US (3) US6221338B1 (es)
EP (1) EP0725624B1 (es)
JP (1) JPH09507049A (es)
AU (1) AU706986B2 (es)
CA (1) CA2174767A1 (es)
DE (1) DE69426459T2 (es)
ES (1) ES2153864T3 (es)
GB (1) GB9322014D0 (es)
WO (1) WO1995011666A1 (es)

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IS1796B (is) 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
TW402506B (en) 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
WO1996023405A1 (en) 1995-02-02 1996-08-08 Akira Kojima Artificial seaweed farm

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AU7998194A (en) 1995-05-22
AU706986B2 (en) 1999-07-01
US8137657B2 (en) 2012-03-20
DE69426459T2 (de) 2001-08-23
GB9322014D0 (en) 1993-12-15
US20020028180A1 (en) 2002-03-07
US20030202944A1 (en) 2003-10-30
JPH09507049A (ja) 1997-07-15
US6582678B2 (en) 2003-06-24
WO1995011666A1 (en) 1995-05-04
EP0725624B1 (en) 2000-12-20
CA2174767A1 (en) 1995-05-04
DE69426459D1 (de) 2001-01-25
US6221338B1 (en) 2001-04-24
EP0725624A1 (en) 1996-08-14

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