IT1204826B - Composizioni farmaceutiche per inalazione - Google Patents

Composizioni farmaceutiche per inalazione

Info

Publication number
IT1204826B
IT1204826B IT19625/86A IT1962586A IT1204826B IT 1204826 B IT1204826 B IT 1204826B IT 19625/86 A IT19625/86 A IT 19625/86A IT 1962586 A IT1962586 A IT 1962586A IT 1204826 B IT1204826 B IT 1204826B
Authority
IT
Italy
Prior art keywords
pharmaceutical compositions
inhalation pharmaceutical
inhalation
microgranules
conglomerate
Prior art date
Application number
IT19625/86A
Other languages
English (en)
Other versions
IT8619625A0 (it
Inventor
Paolo Chiesi
Luciana Pavesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of IT8619625A0 publication Critical patent/IT8619625A0/it
Priority to IT19625/86A priority Critical patent/IT1204826B/it
Priority to PCT/EP1987/000118 priority patent/WO1987005213A1/en
Priority to JP62501911A priority patent/JPS63502895A/ja
Priority to AT87901468T priority patent/ATE94755T1/de
Priority to AU71645/87A priority patent/AU597964B2/en
Priority to KR1019870701005A priority patent/KR940000099B1/ko
Priority to DE198787901468T priority patent/DE258356T1/de
Priority to ES198787102816T priority patent/ES2031839T3/es
Priority to DE87901468T priority patent/DE3787502T2/de
Priority to EP87102816A priority patent/EP0239798B1/en
Priority to HU871760A priority patent/HU202748B/hu
Priority to EP87901468A priority patent/EP0258356B1/en
Priority to ZA871523A priority patent/ZA871523B/xx
Priority to CA000531054A priority patent/CA1297012C/en
Priority to NZ219484A priority patent/NZ219484A/xx
Priority to MYPI87002294A priority patent/MY102928A/en
Priority to FI874710A priority patent/FI90015C/fi
Priority to NO874590A priority patent/NO874590L/no
Priority to GR88300017T priority patent/GR880300017T1/el
Application granted granted Critical
Publication of IT1204826B publication Critical patent/IT1204826B/it
Priority to GR90400695T priority patent/GR3000879T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT19625/86A 1986-03-04 1986-03-04 Composizioni farmaceutiche per inalazione IT1204826B (it)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IT19625/86A IT1204826B (it) 1986-03-04 1986-03-04 Composizioni farmaceutiche per inalazione
HU871760A HU202748B (en) 1986-03-04 1987-02-27 Process for producing filling material usable in inhalation pharmaceutical compositions
JP62501911A JPS63502895A (ja) 1986-03-04 1987-02-27 新規な吸入用製薬組成物
AT87901468T ATE94755T1 (de) 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen.
AU71645/87A AU597964B2 (en) 1986-03-04 1987-02-27 New pharmaceutical compositions for inhalation
KR1019870701005A KR940000099B1 (ko) 1986-03-04 1987-02-27 신규 흡입용 제약 조성물
DE198787901468T DE258356T1 (de) 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen.
ES198787102816T ES2031839T3 (es) 1986-03-04 1987-02-27 Nuevas composiciones farmaceuticas para inhalacion.
DE87901468T DE3787502T2 (de) 1986-03-04 1987-02-27 Pharmazeutische zusammensetzungen zum einatmen.
EP87102816A EP0239798B1 (en) 1986-03-04 1987-02-27 New pharmaceutical compositions for inhalation
PCT/EP1987/000118 WO1987005213A1 (en) 1986-03-04 1987-02-27 New pharmaceutical compositions for inhalation
EP87901468A EP0258356B1 (en) 1986-03-04 1987-02-27 New pharmaceutical compositions for inhalation
ZA871523A ZA871523B (en) 1986-03-04 1987-03-03 Pharmaceutical compositions for inhalation
CA000531054A CA1297012C (en) 1986-03-04 1987-03-03 Pharmaceutical compositions for inhalation
NZ219484A NZ219484A (en) 1986-03-04 1987-03-03 Microgranular excipient for inhalation
MYPI87002294A MY102928A (en) 1986-03-04 1987-09-29 New pharmaceutical compositions for inhalation
FI874710A FI90015C (fi) 1986-03-04 1987-10-26 Fyllnadsaemne och dess anvaendning i farmaceutiska sammansaettningar foer inhalation
NO874590A NO874590L (no) 1986-03-04 1987-11-03 BŸrer fra farmaceutiske blandinger.
GR88300017T GR880300017T1 (en) 1986-03-04 1988-05-20 New pharmaceutical compositions for inhalation
GR90400695T GR3000879T3 (en) 1986-03-04 1990-09-27 New pharmaceutical compositions for inhalation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19625/86A IT1204826B (it) 1986-03-04 1986-03-04 Composizioni farmaceutiche per inalazione

Publications (2)

Publication Number Publication Date
IT8619625A0 IT8619625A0 (it) 1986-03-04
IT1204826B true IT1204826B (it) 1989-03-10

Family

ID=11159814

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19625/86A IT1204826B (it) 1986-03-04 1986-03-04 Composizioni farmaceutiche per inalazione

Country Status (17)

Country Link
EP (2) EP0258356B1 (it)
JP (1) JPS63502895A (it)
KR (1) KR940000099B1 (it)
AT (1) ATE94755T1 (it)
AU (1) AU597964B2 (it)
CA (1) CA1297012C (it)
DE (2) DE3787502T2 (it)
ES (1) ES2031839T3 (it)
FI (1) FI90015C (it)
GR (2) GR880300017T1 (it)
HU (1) HU202748B (it)
IT (1) IT1204826B (it)
MY (1) MY102928A (it)
NO (1) NO874590L (it)
NZ (1) NZ219484A (it)
WO (1) WO1987005213A1 (it)
ZA (1) ZA871523B (it)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
US5376386A (en) * 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
SE9101090D0 (sv) * 1991-04-11 1991-04-11 Astra Ab Process for conditioning of water-soluble substances
JPH0558911A (ja) * 1991-08-27 1993-03-09 N D Shinyaku Kaihatsu Kenkyusho:Kk 鎮咳去痰剤
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
GB9404945D0 (en) 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
WO1996019198A1 (en) 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol drug formulations
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
US6503537B2 (en) * 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6599883B1 (en) * 1998-10-30 2003-07-29 Nastech Pharmaceutical Company, Inc. Nasal delivery of xylitol
DK1283036T3 (da) * 1998-11-13 2008-03-25 Jagotec Ag Törpulver til inhalation
PL196951B1 (pl) 1999-03-05 2008-02-29 Chiesi Farma Spa Proszek do stosowania w inhalatorze suchego proszku, cząsteczki nośnika i sposób wytwarzania nośnika
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
AU6926101A (en) * 2000-06-27 2002-01-08 Vectura Ltd Method of making particles for use in a pharmaceutical composition
PT1913939T (pt) * 2000-06-27 2017-07-19 Vectura Ltd Formulações para utilização em dispositivos inalatórios
PT2283817T (pt) † 2000-11-30 2016-08-22 Vectura Ltd Método de fabrico de partículas para utilização numa composição farmacêutica
AU2002220857A1 (en) 2000-11-30 2002-06-11 Vectura Limited Particles for use in a pharmaceutical composition
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
US8337816B2 (en) 2001-09-17 2012-12-25 Glaxo Group Limited Dry powder medicament formulations
JP2005508220A (ja) * 2001-10-24 2005-03-31 パーリ・ゲーエムベーハー 薬用組成物調製用具
EP1417961A1 (en) * 2002-11-08 2004-05-12 Boehringer Ingelheim International GmbH New pharmaceutical compositions containing a combination of ambroxol or bromhexine and isopropamide iodide
WO2005004845A1 (en) 2003-07-11 2005-01-20 Glaxo Group Limited Pharmaceutical formulations comprising magnesium stearate
AR045914A1 (es) 2003-07-17 2005-11-16 Glaxo Group Ltd Compuesto alcoholico terciario del 8-azoniabiciclo [3.2.1] octano, composicion farmaceutica que lo comprende y su uso para preparar esta ultima
SI1677795T1 (sl) 2003-10-14 2011-04-29 Glaxo Group Ltd Antagonisti muskarinskega acetilholinskega receptorja
EP1677796A4 (en) 2003-10-17 2006-12-27 Glaxo Group Ltd MUSCARIN ACETYLCHOLIN RECEPTOR ANTAGONISTS
PE20050489A1 (es) 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
GB0326632D0 (en) 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
US7384946B2 (en) 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
UY28871A1 (es) 2004-04-27 2005-11-30 Glaxo Group Ltd Antagonistas del receptor de acetilcolina muscarinico
EP1747219A4 (en) 2004-05-13 2010-05-26 Glaxo Group Ltd Antagonists of muscarinic acetylcholine receptor
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
NZ563417A (en) 2005-05-18 2012-01-12 Mpex Pharmaceuticals Inc Aerosolized fluoroquinolones and uses thereof
WO2007022351A2 (en) 2005-08-18 2007-02-22 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
GB0525254D0 (en) 2005-12-12 2006-01-18 Jagotec Ag Powder compositions for inhalation
US7832397B2 (en) 2005-12-28 2010-11-16 Philip Morris Usa Inc. Aerosol powder delivery device
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
CA2739897C (en) 2008-10-07 2017-10-03 Mpex Pharmaceuticals, Inc. Aerosol fluoroquinolone formulations for improved pharmacokinetics
JP5809985B2 (ja) 2009-02-26 2015-11-11 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ ４−｛（１ｒ）−２−［（６−｛２−［（２，６−ジクロロベンジル）オキシ］エトキシ｝ヘキシル）アミノ］−１−ヒドロキシエチル｝−２−（ヒドロキシメチル）フェノールを含む医薬製剤
DK2473170T3 (da) 2009-09-04 2019-08-12 Horizon Orphan Llc Anvendelse af aerosoliseret levofloxacin til behandling af cystisk fibrose
GB0918249D0 (en) 2009-10-19 2009-12-02 Respivert Ltd Compounds
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
HUE038555T2 (hu) * 2010-04-21 2018-10-29 Chiesi Farm Spa Eljárás csökkentett elektrosztatikus töltéssel rendelkezõ részecskék elõállítására
TR201007250A2 (tr) 2010-09-01 2012-03-21 Bi̇lgi̇ç Mahmut Selobioz içeren formülasyon.
UY33337A (es) 2010-10-18 2011-10-31 Respivert Ltd DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
ES2913095T3 (es) 2011-01-31 2022-05-31 Avalyn Pharma Inc Compuestos de pirfenidona y análogos de piridona en aerosol y usos de los mismos
JP6189874B2 (ja) 2012-03-13 2017-08-30 レスピバート・リミテツド 新規製薬学的製剤
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
NZ703866A (en) 2012-07-19 2016-05-27 Adamis Pharmaceuticals Corp Powder feeding apparatus
GB201305825D0 (en) * 2013-03-28 2013-05-15 Vectura Ltd New use
JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク． エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
EP4491180A1 (en) 2014-01-10 2025-01-15 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
DE102016218604A1 (de) 2016-09-27 2018-03-29 Constantin Adams Partikuläres Stoffgemisch, vorzugsweise zur Verwendung bei der Prophylaxe und/oder Behandlung einer Atemwegsstörung
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2023128916A1 (en) * 2021-12-31 2023-07-06 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi An apparatus with a grid (10) for the preparation of dry powder compositions for inhalation

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US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
DE3012136C2 (de) * 1980-03-28 1984-02-16 Bauer, Kurt Heinz, Prof. Dr., 7800 Freiburg Verfahren zur Herstellung eines Granulats

Also Published As

Publication number Publication date
AU7164587A (en) 1987-09-28
JPS63502895A (ja) 1988-10-27
ATE94755T1 (de) 1993-10-15
KR940000099B1 (ko) 1994-01-05
WO1987005213A1 (en) 1987-09-11
FI90015C (fi) 1993-12-27
ZA871523B (en) 1987-08-24
MY102928A (en) 1993-03-31
CA1297012C (en) 1992-03-10
FI874710L (fi) 1987-10-26
IT8619625A0 (it) 1986-03-04
HU202748B (en) 1991-04-29
DE3787502D1 (de) 1993-10-28
EP0258356B1 (en) 1993-09-22
GR3000879T3 (en) 1991-11-15
FI90015B (fi) 1993-09-15
NZ219484A (en) 1989-10-27
FI874710A0 (fi) 1987-10-26
EP0239798B1 (en) 1990-09-26
GR880300017T1 (en) 1988-10-18
DE3787502T2 (de) 1994-01-20
EP0258356A1 (en) 1988-03-09
DE258356T1 (de) 1988-09-01
NO874590L (no) 1987-12-30
AU597964B2 (en) 1990-06-14
EP0239798A1 (en) 1987-10-07
NO874590D0 (no) 1987-11-03
KR880700666A (ko) 1988-04-11
ES2031839T3 (es) 1993-01-01
HUT46533A (en) 1988-11-28

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