ES2155802B1 - PROCEDURE FOR REINFORCING AND EVALUATING THE EFFECTIVENESS OF THE ANTITUMOR ACTIOVITY OF PHARMACOS IN GROSS. - Google Patents

PROCEDURE FOR REINFORCING AND EVALUATING THE EFFECTIVENESS OF THE ANTITUMOR ACTIOVITY OF PHARMACOS IN GROSS.

Info

Publication number
ES2155802B1
ES2155802B1 ES009902062A ES9902062A ES2155802B1 ES 2155802 B1 ES2155802 B1 ES 2155802B1 ES 009902062 A ES009902062 A ES 009902062A ES 9902062 A ES9902062 A ES 9902062A ES 2155802 B1 ES2155802 B1 ES 2155802B1
Authority
ES
Spain
Prior art keywords
procedure
antitumor
reinforcing
actiovity
pharmacos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES009902062A
Other languages
Spanish (es)
Other versions
ES2155802A1 (en
Inventor
Kozo Niwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2155802A1 publication Critical patent/ES2155802A1/en
Application granted granted Critical
Publication of ES2155802B1 publication Critical patent/ES2155802B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/071—Agaricus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Esta invención se refiere a un procedimiento para reforzar una actividad antitumoral mediante la tostadura de una seta que contiene {be}-glucano por rayos infrarrojos lejanos, después la fermentación mediante la adición de "koji", y además la obtención de un agente aceitoso, una composición que contiene un fármaco en bruto al que se aplica tal procedimiento, un procedimiento para evaluar y esperar que la actividad antitumoral en el momento de la administración interna sea mayor cuando aumenta la relación de la cantidad formada por peróxido de lípido, y un procedimiento para evaluar la eficacia antitumoral del tratamiento aplicado al fármaco en bruto mediante el uso de los procedimientos.This invention relates to a method for reinforcing an antitumor activity by roasting a mushroom containing {be} -glucan by far infrared rays, then fermentation by adding "koji", and also obtaining an oily agent, a composition containing a crude drug to which such a procedure is applied, a procedure to evaluate and expect the antitumor activity at the time of internal administration to be greater when the ratio of the amount formed by lipid peroxide increases, and a process to evaluate the antitumor efficacy of the treatment applied to the crude drug through the use of the procedures.

ES009902062A 1998-09-17 1999-09-16 PROCEDURE FOR REINFORCING AND EVALUATING THE EFFECTIVENESS OF THE ANTITUMOR ACTIOVITY OF PHARMACOS IN GROSS. Expired - Lifetime ES2155802B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26375398 1998-09-17
JP10323374A JP2000159682A (en) 1998-09-17 1998-11-13 Crude drug antitumor activity enhancing method, antitumor activity enhancing crude drug-containing composition, antitumor efficacy evaluating method of crude drug treatment, and antitumor efficacy evaluating method of crude drug

Publications (2)

Publication Number Publication Date
ES2155802A1 ES2155802A1 (en) 2001-05-16
ES2155802B1 true ES2155802B1 (en) 2001-12-01

Family

ID=26546176

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009902062A Expired - Lifetime ES2155802B1 (en) 1998-09-17 1999-09-16 PROCEDURE FOR REINFORCING AND EVALUATING THE EFFECTIVENESS OF THE ANTITUMOR ACTIOVITY OF PHARMACOS IN GROSS.

Country Status (19)

Country Link
JP (1) JP2000159682A (en)
KR (1) KR20000023206A (en)
CN (1) CN1255376A (en)
AU (1) AU4486299A (en)
BE (1) BE1012725A5 (en)
CA (1) CA2282234A1 (en)
DE (1) DE19944695A1 (en)
DK (1) DK199901235A (en)
ES (1) ES2155802B1 (en)
FR (2) FR2783426A1 (en)
GB (2) GB9920710D0 (en)
ID (1) ID23150A (en)
IL (1) IL131722A0 (en)
IS (1) IS5183A (en)
IT (1) IT1307267B1 (en)
NL (2) NL1013049C2 (en)
NO (1) NO994463L (en)
SE (2) SE9903307L (en)
SG (1) SG76631A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087603A1 (en) * 2001-04-27 2002-11-07 Ajinomoto Co., Inc. Immunopotentiators
CA2445713A1 (en) * 2001-05-07 2002-11-14 Gab-Gyun Shin A method for preparing lactic acid fermented solution of mushroom and lactic acid fermented solution of mushroom produced thereby
JP4499979B2 (en) * 2001-05-21 2010-07-14 コンビ株式会社 Composition for controlling pathogen infection
EP1393738A4 (en) * 2001-06-01 2004-11-17 Ajinomoto Kk ANTIDIABETIC TREATMENT
JP4826696B2 (en) * 2003-04-07 2011-11-30 ビーエイチエヌ株式会社 Angiogenesis inhibitors
JP4681801B2 (en) * 2002-05-15 2011-05-11 ビーエイチエヌ株式会社 Angiogenesis inhibitor and method for producing the same
TWI330533B (en) 2002-05-15 2010-09-21 Bhn Co Ltd Composition for angiogenesis inhibition, neoplasm inhibition,or immunostimulation
JP2005089417A (en) * 2003-09-19 2005-04-07 Noevir Co Ltd Composition for prevention/treatment of diabetes
JP4587441B2 (en) * 2004-02-12 2010-11-24 株式会社クレハ Novel diabetes treatment and food
JP5034071B2 (en) * 2004-09-17 2012-09-26 株式会社Ｓ・Ｓ・Ｉ Kawariharatake extract that suppresses breast cancer
JP2006273835A (en) * 2005-03-04 2006-10-12 Michishi Tani Malignant tumor therapeutic agent and food and drink containing the same
US20120128856A1 (en) * 2009-07-31 2012-05-24 Ming East-West, Llc Maitake mushroom coffee
JPWO2011081024A1 (en) * 2009-12-29 2013-05-09 株式会社富士見養蜂園 Umami food and production method thereof
CN106309511A (en) * 2016-08-30 2017-01-11 青海民族大学 Effective part of agaricus gennadii for inhibiting CDC25 enzyme as well as preparation method and application of effective part
CN106333969A (en) * 2016-08-30 2017-01-18 青海民族大学 Agaricus gennadii HDAC1 enzyme inhibition effective part and preparation method and application
US20200397817A1 (en) * 2017-11-30 2020-12-24 SHIEH, Darbin Method for predicting and modulating susceptibility of cancer cell to programmed cell death
KR102646421B1 (en) * 2020-12-16 2024-03-12 대한민국 Method for increasing the content of physiologically active ingredients and nutrients in Grifola frondosa
KR102602787B1 (en) * 2020-12-16 2023-11-17 대한민국 Method for increasing the content of physiologically active ingredients and nutrients in Sparassis crispa
KR102584680B1 (en) * 2020-12-17 2023-10-06 대한민국 Method for manufacturing tea of Lentinula edodes tea improved physiological activities and nutrition components

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5276413A (en) * 1975-12-18 1977-06-27 Kureha Chem Ind Co Ltd Production of oncostatic substances
US4177108A (en) * 1977-03-02 1979-12-04 Tetsuro Ikekawa Process for producing emitanin
DE2842691A1 (en) * 1978-09-30 1980-04-10 Karl Dr Med Theurer Activation of pharmaceuticals by irradiation - using wavelengths corresp. to absorption maxima of the substance, opt. with the simultaneous application of magnetic field
JPS57206618A (en) * 1981-06-12 1982-12-18 Noda Shiyokukin Kogyo Kk Preparation of antitumor substance
JPH02203765A (en) * 1989-02-02 1990-08-13 Nippon Beet Sugar Mfg Co Ltd Food having antitumor function and production thereof
JP3357383B2 (en) * 1991-08-14 2002-12-16 昌宏 黒田 Low molecular weight plant composition
JP2955126B2 (en) * 1992-06-22 1999-10-04 笑代 丹羽 Pharmaceutical oleaginous preparation, food oleaginous preparation and production method thereof
US6015913A (en) * 1996-09-06 2000-01-18 Mars, Incorporated Method for producing fat and/or solids from cocoa beans

Also Published As

Publication number Publication date
NL1013049A1 (en) 2000-03-21
ES2155802A1 (en) 2001-05-16
SG76631A1 (en) 2000-11-21
GB9921387D0 (en) 1999-11-10
BE1012725A5 (en) 2001-02-06
DE19944695A1 (en) 2000-03-30
IT1307267B1 (en) 2001-10-30
SE9903307L (en) 2000-03-18
IL131722A0 (en) 2001-03-19
SE9903307D0 (en) 1999-09-16
SE0100195D0 (en) 2001-01-24
CN1255376A (en) 2000-06-07
ITTO990784A1 (en) 2001-03-14
NL1019705C2 (en) 2002-03-26
IS5183A (en) 2000-03-17
GB2341800A (en) 2000-03-29
NL1013049C2 (en) 2002-01-11
FR2788697A1 (en) 2000-07-28
ID23150A (en) 2000-03-23
JP2000159682A (en) 2000-06-13
GB9920710D0 (en) 1999-11-03
SE0100195L (en) 2001-01-24
DK199901235A (en) 2000-03-18
AU4486299A (en) 2000-03-30
NL1019705A1 (en) 2002-01-29
NO994463D0 (en) 1999-09-15
KR20000023206A (en) 2000-04-25
NO994463L (en) 2000-03-20
ITTO990784A0 (en) 1999-09-14
FR2783426A1 (en) 2000-03-24
CA2282234A1 (en) 2000-03-17

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